基于智能agent的癌症相关基因生物医学文献挖掘系统

Shih-Nung Chen, J. Tsai, Wei-Hao Chen
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引用次数: 5

摘要

癌症已经成为威胁人们健康的主要疾病。这就是为什么对致癌因素的研究变得重要的原因。生物医学研究人员虽然可以通过搜索引擎获得大量相关的生物医学文献,但也面临着信息过载的问题。针对生物医学文献的数据挖掘,我们提出了一种智能代理系统,希望能提供帮助。根据用户输入的癌症类型,系统会自动将其与LOH (loss of杂合性)或CGH (comparative genomic hybridization)结合,然后在PubMed中搜索相关的生物医学文献。然后利用决策树对检索到的文献进行分类,同时对癌症相关基因进行挖掘。该方法可以帮助从生物医学文献中挖掘重要信息,从而帮助用户快速方便地获取重要信息。同样,这种方法也可以应用于其他疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An intelligent agent-based biomedical literature mining system for cancer-related genes
Cancer has now become the major disease threatening people's health. That is why research on the factor causing cancer has become significant. Although biomedical researchers can obtain a lot of related biomedical literature through a search engine, they also have to face the problem of information overload as well. We propose an intelligent agent system regarding the data mining of biomedical literature, hoping to provide assistance. According to the type of cancer user enter, the system will automatically combine it with LOH (loss of heterozygosity) or CGH (comparative genomic hybridization), and then search for related biomedical literatures from the PubMed. And then the retrieved literatures will be categorized using the decision tree, with which the cancer-related genes can be mined at the same time. The method can help mine important information from biomedical literatures and thus helps users to gain quick and easy access to important information. Also, this method can be applied to other diseases.
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