Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.最新文献_第3页

In silico discovery of cancer-related genes by functional domain analysis 通过功能域分析在计算机上发现癌症相关基因

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254458

H. Hsiao, J. Tsai, Peixuan Wu, Rouh-Mei Hu

{"title":"In silico discovery of cancer-related genes by functional domain analysis","authors":"H. Hsiao, J. Tsai, Peixuan Wu, Rouh-Mei Hu","doi":"10.1109/MMSE.2003.1254458","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254458","url":null,"abstract":"Clinically, cancer is a complex family of diseases. From the viewpoint of molecular biology, cancer is a genetic disease resulting from abnormal gene expression due to DNA instability, such as translocation, amplification, deletion or point mutations. The purpose was first to perform functional analysis of a set of cancerous genes, and to discover or predict the other human genes that are hypothetically cancer-related. To achieve this goal, an approach consisting of three major components was proposed. Firstly, an automatic system has been developed to collect different data sets from the Internet, like human genes, proteins, and functional domains. Secondly, the functional domain compositions extracted from proteins were adopted for grouping the cancerous genes into a number of clusters by hierarchical clustering and association rule methods. The functional domains commonly existing in a cluster of genes represented the characteristic of that cluster. A second set of hypothetically cancerous genes predicted by single nucleotide polymorphism (SNP) was utilized for testing purpose. The experimental result indicated that a total accuracy of 81.45% was reached. It is anticipates that the proposed approach can be applied to other genetic diseases with minor modification.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129992117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimal resource allocation and sensitivity analysis for modular software testing 模块化软件测试的资源优化分配与灵敏度分析

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254446

Chin-Yu Huang, J. Lo, Jenn-Wei Lin, C. Sue, Chu-Ti Lin

引用次数: 4

A new detection method of halftone images based on crisscross checking technique 一种基于交叉检测技术的半色调图像检测新方法

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254427

Tung-Shou Chen, Jeanne Chen, Yu-Mei Pan

引用次数: 3

Expediting protein structural analysis with an efficient kernel density estimation algorithm 用高效核密度估计算法加速蛋白质结构分析

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254455

Yen-Jen Oyang, Darby Tien-Hao Chang, Chien-Yu Chen, Shien-Ching Hwang

{"title":"Expediting protein structural analysis with an efficient kernel density estimation algorithm","authors":"Yen-Jen Oyang, Darby Tien-Hao Chang, Chien-Yu Chen, Shien-Ching Hwang","doi":"10.1109/MMSE.2003.1254455","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254455","url":null,"abstract":"We describe a kernel density estimation based mechanism aimed at expediting protein structural analysis. We have been motivated by the observation that many protein structural analysis algorithms suffer high time complexity, while only the residues and atoms on the contour of a protein are essential for determining the functions of the protein and how it could interact with the other proteins. Accordingly, for some protein structural analysis problems, it is desirable to invoke a mechanism that can extract the residues and atoms on the contour of a protein in order to expedite the analysis process. The conventional approach to carry out this task is to invoke the /spl alpha/-hull algorithm from computer graphics, which features O(n/sup 2/) time complexity, where n is the number of residues or atoms in the protein. A kernel density estimation based expediting mechanism with an average time complexity of O(nlogn) is proposed. We also report the experiment conducted to evaluate the effects of applying the proposed expediting mechanism to a real protein structural analysis problem. Experimental results reveal that a speedup of 4.8 to 10.3 times can be achieved with minimum impact on the analysis accuracy.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"29 18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121204743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Automated support for data exchange via XML 通过XML自动支持数据交换

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254424

T. Tourwé, L. Stoops, S. Decneut

引用次数: 3

Accelerated migration to collaborative intellectual activities-bioinformatics and knowledge societies 加速向协同智力活动的迁移——生物信息学和知识社会

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254448

H. Yamaguchi

{"title":"Accelerated migration to collaborative intellectual activities-bioinformatics and knowledge societies","authors":"H. Yamaguchi","doi":"10.1109/MMSE.2003.1254448","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254448","url":null,"abstract":"Bioinformatics and computational biology apply mathematical and computer science methods to solve biological problems that involve large amounts of data, computation, and analysis. They are currently receiving a considerable amount of attention. Information technologies play an important role in heterogeneous data management, data modeling, and data analysis. More importantly biological data, and any information that may be derived from such data, need to be accessed and managed easily by biologists. To solve these problems, improved intellectual mobility has been evolving and accelerating bioinformatics and computational biology toward knowledge intensive activities. The desired properties of such acceleration and evolution will be introduced in this talk. These properties include humanization, personalization, and various forms of other IT requirements, especially privacy preservation. This talk also aims at introducing collaborative intellectual activities, which are built on top of a semantic object-relational database, and knowledge societies, which employ some feedback mechanism to achieve the desired properties.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131069229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MMM: a stochastic mechanism for image database queries 一个随机机制的图像数据库查询

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254441

M. Shyu, Shu‐Ching Chen, Min Chen, Chengcui Zhang, C. Shu

引用次数: 18

Robust object detection using cascade filter in MPEG videos 级联滤波器在MPEG视频中的鲁棒目标检测

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254442

Ashraf M. A. Ahmad, Duan-Yu Chen, Suh-Yin Lee

引用次数: 13

A component-based design of a fault-tolerant multimedia communication protocol 基于组件的容错多媒体通信协议设计

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254438

Anil Hanumantharaya, Purnendu Sinha, A. Agarwal

引用次数: 1

Applying combinatorial method to test browser compatibility 应用组合方法测试浏览器兼容性

Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings. Pub Date : 1900-01-01 DOI: 10.1109/MMSE.2003.1254437

Baowen Xu, Lei Xu, Changhai Nie, W. Chu, Chih-Hung Chang

引用次数: 5