World Journal of OtorhinolaryngologyHead and Neck Surgery最新文献

{"title":"Author Guidelines.","authors":"","doi":"10.1002/wjo2.235","DOIUrl":"https://doi.org/10.1002/wjo2.235","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"11 1","pages":"163-170"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Table of Contents.","authors":"","doi":"10.1002/wjo2.189","DOIUrl":"https://doi.org/10.1002/wjo2.189","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"11 1","pages":"i-ii"},"PeriodicalIF":0.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Guidelines.","authors":"","doi":"10.1002/wjo2.224","DOIUrl":"10.1002/wjo2.224","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 4","pages":"357-364"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Table of Contents.","authors":"","doi":"10.1002/wjo2.231","DOIUrl":"https://doi.org/10.1002/wjo2.231","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 4","pages":"i-ii"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Guidelines.","authors":"","doi":"10.1002/wjo2.206","DOIUrl":"https://doi.org/10.1002/wjo2.206","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 3","pages":"244-251"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11369789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to concerns on \"Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China\".","authors":"Meng-Fan Liu, Rui-Xia Ma, Xian-Bao Cao, Jian-Feng Liu, Lei Cheng, Yu-Cheng Yang","doi":"10.1002/wjo2.210","DOIUrl":"10.1002/wjo2.210","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 4","pages":"355-356"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China: Correspondence.","authors":"Hinpetch Daungsupawongm, Viroj Wiwanitkit","doi":"10.1002/wjo2.209","DOIUrl":"10.1002/wjo2.209","url":null,"abstract":"","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 4","pages":"353-354"},"PeriodicalIF":0.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sirt5 affects the metabolic remodeling of eosinophils by negatively regulating the level of succinylation modification of Pkm2 in eosinophilic chronic rhinosinusitis.","authors":"Shun-Yu Wu, Bo-Yu Cai, Zhi-Wen Cao, Tian-Yu Wang, Cai-Quan Liang, En-Hong Xu, Hu Peng, Jianchun-Liao, Huan-Hai Liu","doi":"10.1002/wjo2.186","DOIUrl":"10.1002/wjo2.186","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the role of Sirt5 in regulating eosinophil maturation and activation, specifically focusing on primary eosinophils in mice at the genetic level. Additionally, the study aims to elucidate the underlying mechanism of Sirt5 in eosinophilic inflammation metabolism and identify potential drug targets for the treatment of chronic sinusitis. The findings of this study will provide new insights and a solid theoretical basis for the development of novel therapeutic strategies for eosinophilic chronic rhinosinusitis (eCRS).</p><p><strong>Methods: </strong>Our study investigated the role of Sirt5 gene expression in both non-eCRS and eCRS. We examined the correlation between Sirt5 gene expression and disease severity as well as eosinophil infiltration. Additionally, we utilized a mouse model of eCRS to assess the impact of Sirt5 gene deletion on the disease. To further understand the underlying mechanisms, we conducted experiments at the single-cell level using bone marrow-derived eosinophils. We validated our findings through in vitro culture of eosinophils and intervention experiments. Through these experiments, we aimed to elucidate how Sirt5 regulates target proteins and reshapes their related metabolic pathways.</p><p><strong>Results: </strong>There is a positive correlation between the severity of eCRS and the expression level of Sirt5 in nasal mucosa. Inhibiting Sirt5 expression can effectively alleviate the abnormal activation of eosinophils and the resulting inflammatory response in eCRS-affected nasal mucosa. Sirt5 exerts its influence on eosinophil metabolism by negatively regulating the succinylation level of pkm2, a critical gene in the amino acid biosynthesis pathway.</p><p><strong>Conclusions: </strong>The severity of eCRS is closely associated with the expression level of Sirt5. Sirt5 plays a negative regulatory role in the succinylation level of Pkm2 in eosinophils, thereby influencing metabolic remodeling and functional activation in eCRS. Investigating Sirt5 and its downstream metabolic pathways could offer valuable insights into the disease's pathogenesis and facilitate the development of targeted therapeutic strategies. This research holds significant implications for clinical practitioners involved in the diagnosis and treatment of patients with eCRS.</p>","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"11 1","pages":"86-101"},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agent Orange and head and neck cancer: A systematic review and meta-analysis.","authors":"Neil P Monaghan, Kelsey A Duckett, Shaun A Nguyen, Jason G Newman, Alexandra E Kejner, W Greer Albergotti","doi":"10.1002/wjo2.198","DOIUrl":"10.1002/wjo2.198","url":null,"abstract":"<p><strong>Objective: </strong>To assess the incidence of head and neck cancer in patients exposed to Agent Orange and related dioxins.</p><p><strong>Methods: </strong>Studies were identified through CINAHL, PubMed, and Scopus. Primary studies were identified through April 2023. Articles were included reporting incidence of head and neck cancer and/or deaths due to head and neck cancer in participants exposed to Agent Orange. Meta-analysis of proportions was conducted to calculate incidence and mortality by primary site in those who were exposed to Agent Orange and for control groups. A comparison of proportions was used to compare rates in exposed and control groups.</p><p><strong>Results: </strong>Of 1530 unique abstracts screened, 13 studies were included in the systematic review. Of the exposed patients with reported subsites, oral cavity (31.2%), and larynx (14%) were the most common. Of the exposed patients with reported deaths and subsites, oropharynx (0.25%) was the most common primary site in patients who died. The most common subsites of those who were not exposed, oropharynx (0.13%), and larynx (0.16%). Head and neck cancer of all subsites was more common in those exposed to Agent Orange than in unexposed controls (difference 0.061%; 95% confidence interval: 0.04%-0.08%, <i>p</i> < 0.0001).</p><p><strong>Conclusions: </strong>Our findings suggest that head and neck cancer is more common in those who were exposed to Agent Orange than those who were not. Additionally, individuals exposed to Agent Orange were more likely to die from head and neck cancer. Further investigation is warranted to evaluate subsite-specific outcomes given the limitations of our study design.</p>","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"11 1","pages":"138-146"},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-assisted resection of lateral neck cysts using a postauricular approach.","authors":"Ping Han, Fa-Ya Liang, Pan Song, Ying Li, Pei-Liang Lin, Ren-Hui Chen, Jian-Ming Fan, Xiao-Ming Huang","doi":"10.1002/wjo2.199","DOIUrl":"10.1002/wjo2.199","url":null,"abstract":"<p><strong>Objectives: </strong>The Da Vinci robotic surgical system was used for head and neck surgery. This study aimed to investigate the feasibility, safety, and effect of postauricular approach on the resection of lateral neck cysts.</p><p><strong>Methods: </strong>Eleven patients with lateral neck cysts were enrolled in this retrospective study and accepted robot-assisted surgery via a postauricular approach. Data on volume of cervical cysts, length of incision, bleeding volume, mean operating time, and hospitalization time were analyzed. The postoperative esthetic satisfaction of patients was investigated.</p><p><strong>Results: </strong>In this case series, the average length of the incision was 6.67 cm. Bleeding volumes ranged from 10 to 20 mL. Average operation time was 55 min. Four patients developed postauricular numbness after the operation, and all recovered over 3 months. No other serious adverse events occurred after the operation. Postoperative cosmetic outcomes were satisfactory. During the follow-up median period of 38.2 months, there was no evidence of recurrence or long-term complications.</p><p><strong>Conclusion: </strong>Robot-assisted resection for lateral neck cysts via a postauricular approach is feasible and safe and yields excellent cosmetic outcomes.</p>","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"11 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}