World Journal of OtorhinolaryngologyHead and Neck Surgery最新文献

Author Guidelines. 作者指南。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2024-09-03 eCollection Date: 2024-09-01 DOI: 10.1002/wjo2.206

引用次数: 0

Author Guidelines. 作者指南。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2024-06-06 eCollection Date: 2024-06-01 DOI: 10.1002/wjo2.195

引用次数: 0

Long COVID: From olfactory dysfunctions to viral Parkinsonism. Long COVID：从嗅觉功能障碍到病毒性帕金森病。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2024-04-08 eCollection Date: 2024-06-01 DOI: 10.1002/wjo2.175

Sanyukta Pandey, Vibha Bapat, Jancy Nixon Abraham, Nixon M Abraham

{"title":"Long COVID: From olfactory dysfunctions to viral Parkinsonism.","authors":"Sanyukta Pandey, Vibha Bapat, Jancy Nixon Abraham, Nixon M Abraham","doi":"10.1002/wjo2.175","DOIUrl":"10.1002/wjo2.175","url":null,"abstract":"Neurological and psychiatric complications continue to be a public health concern in long coronavirus disease 2019 (COVID-19). This varies from olfactory dysfunctions such as parosmia to cognitive and emotional challenges. Historically, the surge of neurological disorders followed the viral pandemics, for example, the emergence of Encephalitis Lethargica after the outbreak of Spanish Influenza. During and after COVID-19 infection, the problems associated with the sense of smell and the reports of affected olfactory and limbic brain areas are leading to a growing concern about the similarity with the symptoms and the pattern of degeneration observed at the onset of Parkinson's disease and Alzheimer's disease. These reports reveal the essentiality of long-term studies of olfactory and cognitive functions in the post-COVID era and the experiments using animal models to dissect the neural basis of these complications. In this manuscript, we summarize the research reporting the potential correlation between neurological disorders and viral pandemic outbreaks with a historical perspective. Further, we discuss the studies providing evidence of neurodegeneration due to severe acute respiratory syndrome coronavirus 2 infection by focusing on viral Parkinsonism.","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 2","pages":"137-147"},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Author Guidelines. 作者指南。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2024-03-28 eCollection Date: 2024-03-01 DOI: 10.1002/wjo2.170

引用次数: 0

Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center. 突尼斯一家医疗中心甲状腺癌的流行病学和组织病理学特征。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2023-12-27 eCollection Date: 2024-03-01 DOI: 10.1002/wjo2.147

Maissa Ben Thayer, Fatma Khanchel, Imen Helal, Dorra Chiboub, Hedhli Raoueh, Ehsen Ben Brahim, Raja Jouini, Aschraf Chadli-Debbiche

{"title":"Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center.","authors":"Maissa Ben Thayer, Fatma Khanchel, Imen Helal, Dorra Chiboub, Hedhli Raoueh, Ehsen Ben Brahim, Raja Jouini, Aschraf Chadli-Debbiche","doi":"10.1002/wjo2.147","DOIUrl":"10.1002/wjo2.147","url":null,"abstract":"Background: Thyroid carcinoma (TC) accounts for almost 0.5%-1% of total malignancies. Its incidence is increasing rapidly worldwide. Several studies have drawn up the epidemiological profile of TC and its clinical and pathological features. However, to date, no similar studies have been conducted in Tunisia.Aims: To establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our institute.Materials and methods: We present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4-year period.Results: We collected a sample of 192 cases of TC. It consisted of 31 males and 161 females (83.8%) with a sex-ratio M/F of 0.19. The mean age was 46.4 years. Papillary thyroid carcinoma was the most frequent histological subtype. The multifocality rate was 33.8%. The mean size of TC was 2.2 ± 1.9 cm. 60.9% of TC were staged pT1 and 20.3% had nodal involvement. Papillary thyroid microcarcinomas were noted in 37.5% of cases.Conclusion: Our results were consistent with those of the literature. A high proportion of pT1 and pN0 tumors were noted in our series, suggesting that TC's diagnosis and management was performed at an early stage of the disease in our institution. In addition, our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our institution. Further studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 1","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10979045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Author Guidelines. 作者指导方针。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2023-12-04 eCollection Date: 2023-12-01 DOI: 10.1002/wjo2.144

引用次数: 0

Three cases of uncommon medication-associated osteonecrosis of temporal bone. 三例罕见的药物相关性颞骨骨坏死病例。

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2023-12-03 eCollection Date: 2024-09-01 DOI: 10.1002/wjo2.146

Hunter VanDolah, Jason R Crossley, H Jeffrey Kim

{"title":"Three cases of uncommon medication-associated osteonecrosis of temporal bone.","authors":"Hunter VanDolah, Jason R Crossley, H Jeffrey Kim","doi":"10.1002/wjo2.146","DOIUrl":"10.1002/wjo2.146","url":null,"abstract":"Introduction: Medication-related osteonecrosis of the temporal bone is rare and has been reported to be associated with the use of anti-resorptive and biologic agents. Here, we present the first case of tyrosine-kinase inhibitor-related external auditory canal (EAC) osteonecrosis as well as two cases related to anti-resorptive therapies.Methods: A retrospective case series.Results: Case one: an 84-year-old female presented with chronic otitis externa and osteonecrosis of EACs bilaterally. She had a history of osteoporosis treated with denosumab and risedronic acid. She successfully underwent left EAC reconstruction using an inferiorly-based pedicle periosteal flap while the right ear canal was managed conservatively. Case two: a 69-year-old male presented with osteonecrosis of the right EAC. He had a history of osteoporosis treated with alendronic acid and zoledronic acid. His osteonecrosis is conservatively managed with local debridement and antibiotic application. Case three: a 60-year-old male presented with osteonecrosis of the right inferior EAC. He had a history of chronic myelogenous leukemia treated with a tyrosine-kinase inhibitor, imatinib. After failing conservative therapy, he underwent right ear canal reconstruction using a periosteal vascular pedicle flap without complication and experienced complete resolution to his symptoms.Conclusion: Anti-resorptive agents and/or tyrosine kinase inhibitors may lead to dysregulation of bone remodeling and result in rare cases of temporal bone osteonecrosis. When a local debridement and antibiotic therapy fail, definitive surgical excision of necrotic bone with subsequent reconstruction of the EAC may offer patients a possible resolution in symptoms.","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"10 3","pages":"237-240"},"PeriodicalIF":0.0,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11369790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eosinophil extracellular traps in respiratory ailment: Pathogenic mechanisms and clinical translation 呼吸系统疾病中的嗜酸性粒细胞胞外陷阱:致病机制和临床翻译

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2023-11-01 DOI: 10.1002/wjo2.138

Shun‐Yu Wu, Bo‐Yu Cai, Tian‐Yu Wang, Zhi‐Wen Cao, Hu Peng, Huan‐Hai Liu

{"title":"Eosinophil extracellular traps in respiratory ailment: Pathogenic mechanisms and clinical translation","authors":"Shun‐Yu Wu, Bo‐Yu Cai, Tian‐Yu Wang, Zhi‐Wen Cao, Hu Peng, Huan‐Hai Liu","doi":"10.1002/wjo2.138","DOIUrl":"https://doi.org/10.1002/wjo2.138","url":null,"abstract":"Abstract Background Eosinophilic extracellular traps (EETs) are reticular complexes comprising deoxyribonucleic‐Acid (DNA) fibers and granule proteins. Aims EETs play a crucial role in antimicrobial host responses and are pathogenic when overproduced or under degraded. EETs created by eosinophils appear to enable vital immune responses against extra‐cellular pathogens, nevertheless, trap overproduction is evident in pathology. Materials & Methods As considerably research is performed, new data affirmed that EETs can alter the outcome of respiratory ailment. Results We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic, unresolved inflammation. Discussion Whether EETs can be used as a prospective brand‐new target for the diagnosis, treatment and prognosis of respiratory ailments is a scientific theme worth studying. Conclusion We probe into the disclosure and specificity of EETs produced in reaction to various stimuli and propose a role for those frameworks in ailment pathogenesis and the establishment of chronic, unresolved inflammation.","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"185 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135371673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nasopharyngeal masses in adults—A retrospective analysis of 255 patients to evaluate symptoms, clinical findings, and histological results 成人鼻咽肿块:回顾性分析255例患者的症状、临床表现和组织学结果

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2023-10-30 DOI: 10.1002/wjo2.139

Melanie M. von Witzleben, Adrian von Witzleben, Thomas K. Hoffmann, Janina Hahn

{"title":"Nasopharyngeal masses in adults—A retrospective analysis of 255 patients to evaluate symptoms, clinical findings, and histological results","authors":"Melanie M. von Witzleben, Adrian von Witzleben, Thomas K. Hoffmann, Janina Hahn","doi":"10.1002/wjo2.139","DOIUrl":"https://doi.org/10.1002/wjo2.139","url":null,"abstract":"Abstract Background Nasopharyngeal tissue hyperplasia is generally associated with adenoids in childhood. In adults, nasopharyngeal masses are occasionally found, but data on symptoms, clinical findings, and histologic results are limited. Material and Methods A 10‐year retrospective study was conducted, analyzing data from adult patients who underwent nasopharyngeal biopsies. The study included information on case history, preoperative suspected diagnosis, and histology type. Statistical analysis was performed. Results Two hundred and fifty‐five patients were included, most of them complaining of nasal obstruction, ear pressure, and hearing loss. Biopsy revealed adenoid tissue (64.7%), solid malignancies (15.7%; dominant undifferentiated carcinoma), lymphomas (9.0%), cysts (7.8%), and other benign tumors (2.7%). Malignant neoplasms were predominantly found in male and in elderly patients ( P < 0.0001). If a malignant tumor was suspected initially, histological examination confirmed this in 75% of the cases. 45% of patients with a malignant nasopharyngeal mass had a unilateral seromucous tympanum. Conclusions Persistent nasopharyngeal masses in adults—particularly in elderly men, smokers and those with simultaneous unilateral seromucous tympanum—should undergo a histological examination.","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136069433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is posterior nasal neurectomy the definitive treatment for intractable allergic rhinitis: A prospective study 鼻后神经切除术是顽固性变应性鼻炎的最终治疗方法吗:一项前瞻性研究

World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2023-10-10 DOI: 10.1002/wjo2.133

Saivi Rajdev, Khushboo Goel, Sanjeev Bhagat, Dimple Sahni, Dinesh K. Sharma, Vishav Yadav

{"title":"Is posterior nasal neurectomy the definitive treatment for intractable allergic rhinitis: A prospective study","authors":"Saivi Rajdev, Khushboo Goel, Sanjeev Bhagat, Dimple Sahni, Dinesh K. Sharma, Vishav Yadav","doi":"10.1002/wjo2.133","DOIUrl":"https://doi.org/10.1002/wjo2.133","url":null,"abstract":"Abstract Objectives Allergic rhinitis (AR) has a significant effect on the quality of life and accounts for unproductive times at work and school, causes disturbed sleep patterns and can lead to daytime somnolence. It is fairly prevalent in the world with medical management still being the mainstay of treatment. Patients suffer for a significant number of years before they undergo surgical management for their intractable rhinitis. Thus, this prospective observational study was conducted to reinforce the proficiency of posterior nasal neurectomy in being an effective method for ending this suffering. Methods Thirty patients with troublesome intractable rhinitis underwent posterior nasal neurectomy. Pre‐ and postoperative Visual Analogue Scale (VAS) and Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) scores were compared to study the improvement in nasal and ocular symptoms. Each domain of these scores was studied separately. Results The mean reduction in the VAS was from 6.76 ± 0.884 preoperatively to a mean of 5.33 ± 0.675 at 1 month, 3.81 ± 0.462 at 3 months and 2.53 ± 0.405 at 6 months postoperatively. The mean RQLQ score was reduced from preoperative 4.22 ± 1.091 to a mean of 3.82 ± 1.072 at 1 month, 3.55 ± 1.063 at 3 months and 3.18 ± 1.173 at 6 months postoperatively. Thus, a statistically significant improvement was seen in both mean VAS and RQLQ scores ( P < 0.001), and also when each domain was compared separately. Conclusion Endoscopic posterior nasal neurectomy may be an effective way of improving symptoms in patients with intractable AR and freeing them from long‐term medical regimes, thereby improving their quality of life.","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"149 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136359832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0