Cardiology Research and Reports最新文献

{"title":"Study of Global Longitudinal Strain And N-Terminal Pro Brain Natriuretic Peptide as Predictors of Outcome in Acute St-Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Interventions","authors":"Gehan Magdy","doi":"10.31579/2692-9759/107","DOIUrl":"https://doi.org/10.31579/2692-9759/107","url":null,"abstract":"Objective: Acute ST-segment elevation myocardial infarction (STEMI) patients should be risk-stratified in order to enhance the outcome. Our study was designed to assess the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and global longitudinal strain (GLS) of the left ventricle in patients presenting with acute STEMI and treated by primary percutaneous coronary interventions (PPCI). Methods: the study included 100 STEMI patients treated by PPCI, their age was 55.69 ±8.70 years, all patients were subjected to analysis of NT-proBNP plasma level, and calculation of the GLS, and follow up was done for 6 months for major adverse cardiac events (MACE) occurrence. Results: patients were divided into two groups according to MACE, group I (20 patients who had MACE), group II (80patients without MACE), the NT-proBNP was significantly higher and the GLS was significantly lower in group I, and by multivariate regression analysis GLS was shown to be the most significant predictor of MACE (p value=0.003). Conclusions: Our study concluded that both GLS and NT-proBNP are significantly related to MACE, with GLS being the single most significant predictor for MACE in patients with acute STEMI treated by PPCI.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139310053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of risk factors and complications in patients with myocardial infarction of two types, STEMI and NSTEMI, between the age groups greater than 40 years and less than 40 years","authors":"Maamoun AL- Fawares","doi":"10.31579/2692-9759/101","DOIUrl":"https://doi.org/10.31579/2692-9759/101","url":null,"abstract":"Background: AMI, commonly referred to in general terms as a heart attack, is often caused by reduced or interrupted blood flow to a part of the heart, leading to myocardial necrosis. This is generally the result of a blood clot in the coronary artery that supplies that area of the heart muscle. Methods: An observational study of the type of cross-sectional study. This study targeted the patients of Damascus Hospital. Where the sample was randomly selected, about (200) patients were selected who met specific acceptance criteria, the most important of which is the presence of adequate information in the file, while all patients were excluded according to specific exclusion criteria. - Admission Criteria: Patients admitted to the ambulance or internal department at Al-Mujtahid Hospital, who were treated within the hospital and were not referred to other hospitals. - Exclusion criteria: Patients whose information important for conducting the research was not explicitly documented in the files or who had a lack of basic study information. - Place of study: Damascus Hospital (Al-Mujtahid). - Study time: between 1/12/2023 and 4/15/2023. Results: The most important factors and determinants associated with a higher risk of developing myocardial infarction in a certain age group (under 40 years) than the corresponding ones (over 40 years) according to the conducted statistical analysis: - Under 40 years of age: alcoholism and a family history of death from heart disease. - Over 40 years: BMI, low physical and physical activity, unhealthy diet, atherosclerosis, and high blood pressure. Conclusion: Through our study that compared the risk factors for myocardial infarction, we recommend avoiding all risk factors for myocardial infarction, especially before the age of 40 years, as these factors accelerate the risk of myocardial infarction and the risk of life-threatening complications or even death. Therefore, we recommend the following: - Avoid excessive alcohol consumption at a young age because of its current and cumulative effect on the risk of myocardial infarction. - We recommend that all patients under the age of 40 and those with a family history of myocardial infarction visit a cardiologist regularly for examinations and reassurance. - Maintain low-effort exercise on a daily basis, such as walking. And moderate-intensity sports twice a week for all age groups, especially for those under 40 years old. Many of the risk factors for myocardial infarction do not often exist suddenly or without warning, but rather they are cumulative with age, so paying attention to heart and physical health before the age of 40 has the greatest impact in preventing or avoiding the risks of infection in the future.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"301 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139356783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linum Usitatissimum Oil Fraction Reverse Cardiac Remodeling at Molecular Level: Suppressing Mirna-29b And Mirna 1 Genes in Isoproterenol in Vivo Model","authors":"Jilan A. Nazeam","doi":"10.31579/2692-9759/100","DOIUrl":"https://doi.org/10.31579/2692-9759/100","url":null,"abstract":"Linum usitatissimum (flaxseed) produce one of the oldest commercial oils which use traditionally as a functional food for lowering cholesterol level. Nevertheless, to date, there is no scientific evidence to assess the role of flaxseed oil in cardiac remodeling management. The study aimed to clarifying the underlying mechanism of standardized oil to restore cardiac remodeling in a heart toxicity rat model induced by isoproterenol (ISO). Oil fraction was purified, and major components were identified by gas-chromatography-mass spectrometry (GC-MS). The in vivo tests were conducted by ISO (85 mg/kg/ twice subcutaneously) with 24 hours between each dose. The rats were treated with flaxseed oil fraction (100 mg/kg orally) and the same dose was used for omega 3 as a positive control group. GC- MS revealed that α-linolenic acid (24.6%), oleic acid (10.5%), 6-octadecenoic acid (Z), 2,3 dihydroxypropyl ester (9.0%), 2,3-dihydroxypropyl elaidate (7.0%), n-propyl 9,12,15-octadecatrienoate (6.0%) are the major components. After 4 weeks of oil uptake, the results revealed an improvement in cardiac function, a decrease in apoptosis, and simultaneous prevention of myocardial fibrosis. The levels of BNP, NT-pro-BNP, endothelin-1, Lp-PLA2, and MMP2, and cTnI and cTn were significantly decreased, and a higher plasma level of Topo 2B was observed, moreover, miRNA − 1 and 29b were downregulated. Current evidence provide insight into the mechanism of flaxseed oil to restore cardiac remodeling, which supports its future application as cardioprotective against heart diseases.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139356672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why Haven't We Been Able to Reduce the Prevalence of Obesity?","authors":"F. A. Palacios","doi":"10.31579/2692-9759/102","DOIUrl":"https://doi.org/10.31579/2692-9759/102","url":null,"abstract":"This editorial is dedicated to the doctors, collaborators, and the educational unit Liceo Panamericano de Guayaquil from the IN.PE.TU program, who have trusted in an academic concern that is relevant, significant, and opens possibilities for research, analysis, and resolution.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139356709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management Of Therapy of Anticoagulants and Antiplatelets in Acute Gastrointestinal Bleeding and In the Periendoscopic Period","authors":"N. Tsonev, D. Vandeva, K. Toncheva, D. Zvezdov","doi":"10.31579/2692-9759/076","DOIUrl":"https://doi.org/10.31579/2692-9759/076","url":null,"abstract":"Management of anticoagulant and antiplatelet therapy is a common clinical problem in case of urgent or elective gastrointestinal endoscopic procedures. Anticoagulants and antiplatelet agents are widely used drugs for cardiovascular prevention and reducing the risk of thromboembolic events. Gastrointestinal bleeding represents a serious complication of their use. It’s recommended temporary interruption of anticoagulants in clinically significant gastrointestinal bleeding. For the antiplatelet therapy the decision is when to stop and restart the therapy, depending on whether it’s for primary or secondary cardiovascular prevention. Treatment with antithrombotic drugs in the periprocedural endoscopic period is based on balancing the bleeding risk against the thromboembolic risk. It’s recommended temporary discontinuation of antithrombotic treatment in high-risk endoscopic procedures with high risk for bleeding and to consider the use of “bridging” therapy with LWMH for patients on vitamin K antagonists who are at high thrombotic risk. Antithrombotic agents in endoscopic procedures with lower bleeding risk are not needed to be withheld. Evaluating cardiovascular risk and management of antithrombotic therapy could be a challenge for gastrointestinal endoscopists, therefore collaboration with a cardiologist is of great importance, at least for some patients.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116325213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial Infarction: Risk Factors, Pathophysiology, Classification, Assessment and Management","authors":"Abdelmonem Awad Hegazy","doi":"10.31579/2692-9759/056","DOIUrl":"https://doi.org/10.31579/2692-9759/056","url":null,"abstract":"Myocardial infarction is a serious health problem affecting populations worldwide. Proper and prompt diagnosis and management is critical to achieving good prognosis and avoiding or reducing morbidity and mortality. It is essential for clinicians to be aware of the risks, diagnosis and treatment. In this review we aim to update and discuss knowledge of myocardial infarction with respect to risk factors, pathophysiology, types or classification, clinical manifestations, diagnosis and treatment in a concise and simplified manner in order to define a simple comprehensive guide for clinicians. The available literature has been searched, reviewed, studied, analyzed, written in a simple understanding method, discussed and concluded. For prophylaxis, it has been found that moderate muscular exercise, regular consumption of fresh vegetables and fruits, avoidance of smoking and stress, and low consumption of fat are associated with reduced risk of coronary heart disease in populations of all age groups worldwide. The diagnosis of myocardial infarction is based primarily on evaluations of clinical features, typical abnormalities in ST-segment and T wave of ECG findings and rise in cardiac enzymes or biomarkers such as plasma troponin. At the same time, the key to treatment is reperfusion of the myocardium and restoration of coronary blood flow.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126058501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Bicuspid Aortic Valve – Various Phenotypic Expressions","authors":"Timothy E Paterick","doi":"10.31579/2692-9759/055","DOIUrl":"https://doi.org/10.31579/2692-9759/055","url":null,"abstract":"The phenotypic expressions of the bicuspid aortic valve (BAV) are unpredictable, and difficult to compartmentalize. In current times the BAV is noted to represent approximately 50% of isolated severe aortic stenosis cases requiring surgery, and has been associated with aortic regurgitation, bacterial endocarditis and aortic dissection. Echocardiography is the diagnostic test to identify BAV. The clinical associations coupled with the high prevalence of BAV have made this an important area of clinical inquiry. We will explore the vast horizons and multifaceted challenges of the bicuspid aortic valve and our current understanding of this complex entity.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120847448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Hypogonadism on Quality of Life in Men with Coronary Artery Disease","authors":"O. Khaniukov","doi":"10.31579/2692-9759/064","DOIUrl":"https://doi.org/10.31579/2692-9759/064","url":null,"abstract":"Today, the issue of improving care for patients with cardiovascular diseases is particularly acute, because despite all the achievements of modern medicine, they remain one of the leading causes of disability and mortality in Europe and the world. Despite the fact that many factors have been established that affect the prognosis and course of cardiovascular diseases, such as arterial hypertension, smoking, gender, obesity, age, diabetes mellitus, obesity, metabolic disorders, etc.,[1] their search continues. So, the factor influencing the course of cardiovascular diseases is the presence of androgen deficiency in men. According to studies [2],[3],[4],[5],[6] conducted in world practice, there is evidence that androgen deficiency has a negative impact on the course of cardiovascular diseases, in particular coronary artery disease. However, this issue requires further study. The aim of the study was to study the possible impact of androgen deficiency on the quality of life in men with coronary heart disease.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129663682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Correction of Tricuspid Component of Patients with Multi-Vessel Heartdefect.","authors":"A. Kh","doi":"10.31579/2692-9759/062","DOIUrl":"https://doi.org/10.31579/2692-9759/062","url":null,"abstract":"The analysis of results of surgical correction of 326 (8%) patients with tricuspid pathology in rheumatic multi-valve heart defects. The age of our patients ranged from 12 to 74 years (mean 36.7 + 9.4). Women were 220 (67.5%), while men - 106 (32.5%). According to the degree of circulatory disorders, patients were divided according to the classification of chronic heart failure (CHF) in NYHA, where in functional class III were assigned 24 (7.4%), and to IY functional class NYHA - 302 (92.6%) patients. The clinic is the most commonly used plastic fibrous ring by De Vega. Of the 262 (80.5%) operated by the method of De Vega, at 26.9% after correction of regurgitation on tricuspid valve (TC) virtually disappeared, at 62.8% - regurgitation decreased from a low of 1 degree, and the remaining 10.3% were operated last was reduced to 2 (moderate) degree. In 8 (2.46%) cases of infective endocarditis was made \"open\" correction - prosthetics TC biological prosthesis. Known methods of creating a bicuspid tricuspid valve - Kay Reed Kay Boyd used in 13.4% of cases, but in recent years because of the low efficiency of data communication techniques greater preference for annuloplasty by De Vega.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"157 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122136054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic Valve Endocarditis Post Ventricular Septal Defect Device Closure: Case Report","authors":"Y. Mubarak","doi":"10.31579/2692-9759/063","DOIUrl":"https://doi.org/10.31579/2692-9759/063","url":null,"abstract":"Ventricular septal defect (VSD) is a common congenital heart disease (CHD) in childhood, and its incidence is about 20% of CHD. Surgical closure or repair is safe with acceptable results. Transcatheter VSD closure offers excellent results. Coil system is developed for transcatheter VSD occlusion. Infective endocarditis (IE) post device implantation is very rare; however, it is possible. IE represents a surgical challenge associated with perioperative mortality","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132213069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}