Myocardial Infarction: Risk Factors, Pathophysiology, Classification, Assessment and Management

Abdelmonem Awad Hegazy
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Abstract

Myocardial infarction is a serious health problem affecting populations worldwide. Proper and prompt diagnosis and management is critical to achieving good prognosis and avoiding or reducing morbidity and mortality. It is essential for clinicians to be aware of the risks, diagnosis and treatment. In this review we aim to update and discuss knowledge of myocardial infarction with respect to risk factors, pathophysiology, types or classification, clinical manifestations, diagnosis and treatment in a concise and simplified manner in order to define a simple comprehensive guide for clinicians. The available literature has been searched, reviewed, studied, analyzed, written in a simple understanding method, discussed and concluded. For prophylaxis, it has been found that moderate muscular exercise, regular consumption of fresh vegetables and fruits, avoidance of smoking and stress, and low consumption of fat are associated with reduced risk of coronary heart disease in populations of all age groups worldwide. The diagnosis of myocardial infarction is based primarily on evaluations of clinical features, typical abnormalities in ST-segment and T wave of ECG findings and rise in cardiac enzymes or biomarkers such as plasma troponin. At the same time, the key to treatment is reperfusion of the myocardium and restoration of coronary blood flow.
心肌梗死:危险因素、病理生理学、分类、评估和管理
心肌梗死是影响全世界人口的严重健康问题。正确和及时的诊断和管理是实现良好预后和避免或减少发病率和死亡率的关键。临床医生必须了解风险、诊断和治疗。在这篇综述中,我们旨在以简明和简化的方式更新和讨论心肌梗死的危险因素,病理生理学,类型或分类,临床表现,诊断和治疗方面的知识,以便为临床医生定义一个简单的综合指南。对现有文献进行检索、复习、研究、分析,用简单易懂的方法进行写作、讨论和总结。在预防方面,已经发现,在全世界所有年龄组的人群中,适度的肌肉运动、经常食用新鲜蔬菜和水果、避免吸烟和压力以及低脂肪摄入与降低冠心病风险有关。心肌梗死的诊断主要基于临床特征的评估、心电图st段和T波的典型异常以及心肌酶或血浆肌钙蛋白等生物标志物的升高。同时,治疗的关键是心肌再灌注和冠状动脉血流的恢复。
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