Medicinski Podmladak最新文献

{"title":"CT guided minimal invasive oxygen ozone therapy in patients with degenerative changes of lumbosacral spine","authors":"K. Davidović, M. Ercegovac, R. Maksimovic","doi":"10.5937/mp73-40088","DOIUrl":"https://doi.org/10.5937/mp73-40088","url":null,"abstract":"Degenerative spine conditions involve the gradual loss of normal structure and function of spine over time. They are usually caused by aging, but may also be the result of tumors, infections or arthritis. Pressure on the spinal cord and nerve roots caused by degeneration can be caused by herniated discs. Degenerative disc disease is one of the most common causes of low back and neck pain, and also one of the most misunderstood ones. Low back pain (LBP) is a common disorder affecting an increasing number of people worldwide, whose diagnosis is focused on the identification of triggering causes. First line therapy usually starts from conservative approaches, whereas second line treatments include a spectrum of minimally invasive techniques, before resorting to more invasive surgical approaches. Among minimally invasive techniques, percutaneous oxygen-ozone injections represent one of the most common and cost-effective procedures. Oxygen-ozone therapy is a minimally invasive treatment for lumbar disc herniation that uses the biochemical properties of the gas mixture of oxygen and ozone. Intradiscal, periradicular or intraarticular ozone therapy is used in patients that do not respond to standard conservative therapies for low back pain due to degenerative disc-induced lumbar disc herniation (LDH) or other degenerative process of nearby structures such as zygapophyseal articulations. All the interventional procedures for low back pain may be guided by ultrasound, computerized tomography or fluoroscopy.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71007955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress among international medical students during COVID-19 pandemic: A cross-sectional study","authors":"M. Milanović, Emilia Mijatović, Milena Đokić, Tamara Stanisavljević, Ana Đokić, N. Milic, Anđa Ćirković, Nina Rajovic","doi":"10.5937/mp73-33990","DOIUrl":"https://doi.org/10.5937/mp73-33990","url":null,"abstract":"Introduction: The aim of this study was to investigate the prevalence of stress among international medical students and factors associated with higher levels of student's stress during the COVID-19 epidemic in Serbia. Material and methods: The cross-sectional study was conducted using a five-section online questionnaire during January, 2021 among international medical students attending the Faculty of Medicine University of Belgrade, Studies in English in Serbia, using snowball sampling method. Results: A total of 52 international medical students with a mean age of 21.0 ± 2.2 years, 58% female, were enrolled. Stress level was rated higher than usual in 65% of students. The predictors of higher level of stress were: not being prepared for full online courses (p = 0.058), worry about own health (p = 0.04), worry about the health of loved ones (p = 0.058), concern about finances (p = 0.004) and exams/future study plans (p = 0.033), lack of energy (p = 0.012), strong emotions or mood swings (p = 0.004) and inability to get needed things from stores (p = 0.054). Fear or worry about the health of their loved ones, concern about money, as well as concern about exams or future study plans were independent predictors of the respondents' higher level of stress in multivariate analysis. Conclusion: The COVID-19 pandemic has led to an increase in the level of stress among the international medical students in Serbia. A higher level of stress was associated with fear about health of loved ones, concern about finances and exams/future study plans.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71007083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of pediatric urolithiasis","authors":"Milena Đokić, Ana Đokić, Milica Dobrodolac, P. Ilić","doi":"10.5937/mp73-37951","DOIUrl":"https://doi.org/10.5937/mp73-37951","url":null,"abstract":"Introduction: Surgical treatment of urolithiasis in children is quite complex and specific due to certain anatomical and functional features of childhood. Methods of surgical treatment at this age are: extracorporeal lithotripsy (ESWL), intracorporeal (endoscopic) lithotripsy - pneumatic and laser, percutaneous nephrolithotripsy (PCNL) and open surgery. Aim: The aim of this study was evaluation of the effects of ureterorenoscopy and endoscopic lithotripsy in children, as methods of minimally invasive surgical treatment. Material and methods: The retrospective study was conducted at the Institute for Mother and Child Health Care of Serbia \"Dr Vukan Cupic\" in Belgrade from 2010 to 2020. The study included 112 patients (50 boys and 62 girls) aged 1-18 years with urolithiasis, treated by endoscopic (laser or pneumatic) lithotripsy. The retrospective study was conducted at the Institute for Mother and Child Health Care of Serbia \"Dr Vukan Cupic\" in Belgrade from 2010 to 2020. The study included 112 patients (50 boys and 62 girls) aged 1-18 years with urolithiasis, treated by endoscopic (laser or pneumatic) lithotripsy. Results: After one ureterorenoscopy, the calculus was successfully disintegrated in 87 (78%) patients: in the renal pelvis in 22 (79%), in the upper pole calices of the kidney in 14 (100%), in the lower pole calices in 10 (50%), in the proximal segment of the ureter in 10 (83%), in the distal segment of the ureter in 27 (79%), in the bladder in 4 (100%) cases. In 19 (17%) patients the second intervention was necessary: in the renal pelvis in 28 (100%), in the upper pole calices in 14 (100%), in the lower pole calices in 14 (70%), in the proximal segment of the ureter in 12 (100%), in the distal segment of the ureter in 34 (100%) and in the bladder in 4 (100%) patients. Conclusion: The primary treatment of pediatric urolithiasis is ureterorenoscopy in combination with pneumatic or laser lithotripsy. It is successfully used in all segments of the urinary tract. The procedure is partially limited in the lower pole calices of the kidney, due to anatomical circumstances and mechanical limitations of the instruments.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"126 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71007533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Citing literature in biomedical research","authors":"V. Pavlovic, N. Milić","doi":"10.5937/mp73-34969","DOIUrl":"https://doi.org/10.5937/mp73-34969","url":null,"abstract":"Even though it is considered to be the least demanding part while writing a paper, significant attention should be devoted to citing literature. By using citation, original authors are acknowledged, readers are directed to the used material, validity of the used sources is confirmed, evidence of current research is provided, and plagiarism is avoided. Numerous shortcomings in the citation of scientific literature have been recognized in recent times. Results of a recent meta-analysis showed that 25.4% of published scientific papers consisted of citation errors. The academic community encounters the problems of incorrect citations on a daily basis, and assessing the accuracy of citations requires considerable effort. Most researchers are aware of the presence of various citation errors, but few respect their presence, i.e., the consequences of the identified problem. Assessing the presence and type of inaccurate citations in the biomedical scientific literature, as well as identifying factors associated with their presence, is important for preserving the integrity of the academic community. To improve citation accuracy in the biomedical scientific literature, recommendations for authors, mentors, readers and editors should be implemented in academic environment. These recommendations would encourage good citation practice, prevent errors and promote progress throughout the scientific community.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71006898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prophylaxis and management of chemotherapy-induced febrile neutropenia: The role of myeloid growth factors","authors":"J. Dimitrijevic, M. Stojanović","doi":"10.5937/mp73-36780","DOIUrl":"https://doi.org/10.5937/mp73-36780","url":null,"abstract":"Febrile neutropenia is a serious chemotherapy-related adverse event that can lead to complications and death and it could be a significant burden on the organization of the health care system. The risk for febrile neutropenia is determined by chemotherapy-induced myelosuppression and the presence of patient-related risk factors. In the literature, various patient-related risk factors are taken into consideration. It was suggested that the patient age is the one of the most important ones. If the estimated risk for the febrile neutropenia is high, prophylactic use of myeloid growth factors (granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor) is recommended. In patients with solid tumors and lymphomas it was shown that the prophylactic use of myeloid growth factors significantly reduces the incidence of febrile neutropenia, early mortality during chemotherapy and infection-induced mortality. In patients who develop febrile neutropenia, there is less evidence for the therapeutic use of myeloid growth factors compared to prophylactic use, although there is a clear benefit in reducing the time to neutrophil count recovery. There is a clear benefit for hospitalized patients, also, in reducing duration of hospitalization. In patients with febrile neutropenia who have not been previously treated with prophylactic myeloid factors, assessment of risk factors for the complications is advised. In patients with high-risk febrile neutropenia therapeutic use of growth should be considered.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71006916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of traumatic exposure on thymus weight level after dexamethasone application in rats","authors":"M. Knežević, Milica Ivanišević, Natalija Kojović, A. Starcevic","doi":"10.5937/mp73-33448","DOIUrl":"https://doi.org/10.5937/mp73-33448","url":null,"abstract":"Introduction: Thymus is the central lymphoid organ responsible for proper immune cell maturation, hence ensuring functional T cell repertoire. Stress induces elevated levels of hormones that profoundly alter immune response. Susceptibility to physiologically synthesised and exogenously applied glucocorticoids make thymus an ideal substrate for anatomical and morphological analysis. Aim: Our research aimed to investigate the impact of endogenous and exogenous glucocorticoids on thymus weight level. Material and methods: Experimental procedure was conducted on male Wistar rats, 12 in total, divided into 2 groups - control and experimental. Latter was exposed to two kinds of stressors. Acute stress included immobilization with exposure to the predator's odor. Chronic social stress included rotation of the animals held in pairs. On the 11th day of the experimental procedure, half of the experimental group received dexamethasone treatment (impact of endogenous + exogenous glucocorticoids) while the other half did not (impact of endogenous glucocorticoids). After the experiment, animals were sacrificed and their thymuses were obtained and measured. For statistical analysis, ANOVA was used to test differences between groups and LSD test for each group testing. Results: Results showed statistically significant differences between the thymus mass of different groups (F=4.336, p=0.048). The part of the experimental group that received dexamethasone had a smaller thymus weight level compared to the part of the experimental group that received no treatment (p=0.024). No statistically relevant results were obtained after comparing thymus masses from impact of endogenous glucocorticoids and control group (p>0.05). Conclusion: Exogenous glucocorticoids induce morphological changes in thymus which are observed in decreased weight level. Stress induced thymus apoptosis, but it was not sufficient to lead to decrease in thymic mass. Our further experiments will put emphasis on understanding of morphological and anatomical changes caused by stress.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71006421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sources of information among medical students during the COVID-19 pandemic","authors":"Milena Đokić, Ana Đokić, Tamara Stanisavljević, N. Milic, J. Milin-Lazović","doi":"10.5937/mp73-33504","DOIUrl":"https://doi.org/10.5937/mp73-33504","url":null,"abstract":"Introduction: The use of relevant sources of information and a high level of knowledge about risky behavior and ways of COVID-19 transmission are crucial for disease prevention and its spread. Aim: The aim of this study was to assess sources of information among medical students during the COVID-19 pandemic. Material and methods: This cross-sectional study was conducted on 373 students of the Faculty of Medicine University of Belgrade. The anonymous questionnaire consisted of 3 parts: socio-demographic characteristics, information sources and the attitude towards available information about COVID-19. Questionnaire was available online during January 2021. Results: At the beginning of the pandemic, one third of the students were informed several times a day (37.5%), latter it would drop to being informed several times a week (33.8%) (p < 0.05). Television and official websites were stated as the main information sources during the pandemic. Students of IV - VI year of medical school significantly more often informed themselves from official websites in contrast to I - III year students (75.5% vs 61.6%, p = 0.014). More than 2/3 of the students stated that the information about the coronavirus is accurate and up-to-date, but only a third were satisfied with the information during the pandemic. Conclusion: A large number of arteriolosclerotic CSVD patients complain of different types of headaches. The results of this study should emphasize the importance of mass and social media to public health policymakers as the most common sources of public information, which can reduce the spread of inaccurate information that can affect people's behavior towards a pandemic. This study also accentuated the need to make the younger student population aware of the importance of using relevant and reliable sources of information.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71006952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The key factors associated with public health workers' intention to leave a job","authors":"K. Tripković, Milena Šantrić-Milićević","doi":"10.5937/mp73-38216","DOIUrl":"https://doi.org/10.5937/mp73-38216","url":null,"abstract":"A particularly important issue in healthcare settings is public health professionals' intention to leave their job, which may exacerbate both existing and forecasted public health workforce shortages and jeopardize the health system's performance. The rate of intention to leave a job varies across countries and among different profiles of health workers. It is well documented that job dissatisfaction facilitates the intention to leave. Organizational factors (such as job-related stress, interpersonal relationships with colleagues and supervisors, opportunities for professional development, nature of work, and organizational culture) are considered to have the most significant impact on public health workers' intention to leave a job. However, the relevance of individual factors (gender, age, marital status) and other factors (e.g., number of family members, community satisfaction, and family responsibilities) is less clear. It is of great importance that policymakers and managers in health facilities implement effective retention strategies in order to ensure continued delivery of both health care and public health services, and prepare for response to future crises. Retention strategies should be oriented towards ensuring public health workers' health and safety, increasing job satisfaction, recognizing their value and achievements, and creating supportive work environments.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71007219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of right ventricular function for the outcome of treatment and remodeling of the heart after left ventricular assist device implantation","authors":"D. Terzić, A. Mikic","doi":"10.5937/mp73-38192","DOIUrl":"https://doi.org/10.5937/mp73-38192","url":null,"abstract":"The efficiency of the device for permanent circulatory support of the left ventricle has been proven through clinical practice with the trend of constant improvement of treatment results along with biotechnological progress and improvement of surgical implantation techniques. The published reports of most reference cardiac surgery centers present a one-year survival rate of over 85%, a two-year survival rate of 70% and a five-year survival rate of 45-50%. In addition to clear benefits for the patient, implantation of LVAD also carries significant specific risks, so infections, post-implantation bleeding, strokes, and right ventricular postimplantation weakness are the most common complications. Given that the progress of the LVAD program is ensured primarily by reducing the incidence of complications not related to the functioning of individual segments of the cardiovascular system, and as left ventricular function is completely replaced by LVAD device, the most recent challenge is the decision to install LVAD device in the heart with right ventricular, given that the postimplantation weakness of right ventricular is associated with proven increased mortality and morbidity. Since the 1990s, studies on hearts with implanted LVAD as a bridge to heart transplantation have shown regression of cell hypertrophy, normalization of cell size, muscle fiber architecture, and heart chamber geometry. The described changes are characterized by the notion of reverse remodeling, which is synonymous with function recovery. It is this process at the level of the right ventricle that is recognized as extremely important for the success of LVAD programs, especially in the group of patients who have a certain degree of right ventricular weakness preoperatively. The basic requirements of the cardiac surgery team are adequate preoperative assessment of right ventricular weakness, then application of measures to prevent damage and load on the right ventricle during and after LVAD implantation, as well as providing adequate therapeutic measures for right ventricular recovery in the postimplantation period.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71007590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of different types of irritable bowel syndrome in patients with nonalcoholic fatty liver","authors":"Divna Popović, Stefan SR. Rosic, S. Lukić","doi":"10.5937/mp73-33427","DOIUrl":"https://doi.org/10.5937/mp73-33427","url":null,"abstract":"Introduction: Non-alcoholic fatty liver (NAFLD) is an excessive accumulation of fat, detected by imaging methods or histologically, in people who haven't consumed alcohol, associated with insulin resistance and metabolic syndrome. Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder, diagnosed by Rome IV criteria, with no morphological disorders in the digestive system. Aim: Detecting frequency between different types of IBS in different grades of steatosis to distinguish possible association between the two diseases. Material and methods: In retrospective study at the Clinic for Gastroenterohepatology of the University Clinical Center of Serbia, from January to June 2020, a number of 49 patients over 18 years were diagnosed with NAFLD and IBS. Based on the ultrasound examination, patients are classified into those with grades I, II and III of steatosis, and according to the Roma IV criteria, into IBS-C, IBS-D and IBS-M type. Body Mass Index (BMI), hyperglycemia, cholesterol, triglycerides, ALT, AST, gGT, Diabetes Mellitus (DM), arterial hypertension, Gastroesophageal Reflux Disease (GERD) and cholelithiasis are examinated. Results: In retrospective study at the Clinic for Gastroenterohepatology of the University Clinical Center of Serbia, from January to June 2020, a number of 49 patients over 18 years were diagnosed with NAFLD and IBS. Based on the ultrasound examination, patients are classified into those with grades I, II and III of steatosis, and according to the Roma IV criteria, into IBS-C, IBS-D and IBS-M type. Body Mass Index (BMI), hyperglycemia, cholesterol, triglycerides, ALT, AST, gGT, Diabetes Mellitus (DM), arterial hypertension, Gastroesophageal Reflux Disease (GERD) and cholelithiasis are examinated. Conclusion: Patients with NAFLD and IBS are predominantly female. Non-alcoholic fatty liver is associated with metabolic syndrome, insulin resistance, GERD, and cholelithiasis. No association was shown between the grade of steatosis and the type of IBS, except in cholesterol, with the highest frequency in grade III of steatosis and the IBS-C type.","PeriodicalId":31558,"journal":{"name":"Medicinski Podmladak","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71006493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}