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Journal of Pathology of Nepal最新文献

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A study of correlation of plasma fibrinogen levels with glycemic status in type 2 Diabetes Mellitus patients 2型糖尿病患者血浆纤维蛋白原水平与血糖状态的相关性研究
Journal of Pathology of Nepal Pub Date : 2020-09-30 DOI: 10.3126/jpn.v10i2.28706
Pravinkumar Ghongade, Manisha A. Atram, V. Shivkumar
{"title":"A study of correlation of plasma fibrinogen levels with glycemic status in type 2 Diabetes Mellitus patients","authors":"Pravinkumar Ghongade, Manisha A. Atram, V. Shivkumar","doi":"10.3126/jpn.v10i2.28706","DOIUrl":"https://doi.org/10.3126/jpn.v10i2.28706","url":null,"abstract":"Complications; Glycated hemoglobin; Plasma fibrinogen; Type 2 diabetes mellitus; Background: Plasma fibrinogen is an indicator of inflammation and endothelial dysfunction has been described as an independent risk factor for cardiovascular morbidity in type 2 Diabetes mellitus patients. Poor glycemic control has been reported to be associated with hyperfibrinogenemia and its complications. This study was aimed to find a correlation of mean fibrinogen level with glycemic control in complicated and uncomplicated cases of Type 2 Diabetes mellitus.","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"24 1","pages":"1746-1750"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85160488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A correlative study between maternal hemoglobin concentration during third trimester and fetal birth weight of babies born at Kathmandu Medical College and Teaching Hospital 加德满都医学院及教学医院妊娠晚期产妇血红蛋白浓度与胎儿出生体重的相关性研究
Journal of Pathology of Nepal Pub Date : 2020-09-30 DOI: 10.3126/jpn.v10i2.30108
A. Shrestha, S. Shrestha
{"title":"A correlative study between maternal hemoglobin concentration during third trimester and fetal birth weight of babies born at Kathmandu Medical College and Teaching Hospital","authors":"A. Shrestha, S. Shrestha","doi":"10.3126/jpn.v10i2.30108","DOIUrl":"https://doi.org/10.3126/jpn.v10i2.30108","url":null,"abstract":"Background: Anemia is one of the commonest health problems faced by pregnant women in both developing and developed countries. Maternal anemia is a potential risk factor for fatal outcomes like low birth weight and preterm delivery. This study intended at comparing the birth weight of the babies who were born to mothers with and without anemia during the third trimesters. \u0000Materials and methods: This study is a descriptive, cross-sectional study conducted at Kathmandu Medical College, Teaching Hospital from July 2019 to June 2020. The third-trimester hemoglobin of mothers was recorded along with the birth weight of their respective babies. Mothers with regular antenatal care visits at this hospital were included and the known causes for anemia like renal disorders, twin pregnancies, and others were excluded from the study. The third-trimester hemoglobin level of all pregnant females was correlated with the birth weight of the babies. \u0000Results: Out of a total of 2417 pregnant women, 317 (13%) had anemia. The overall prevalence of low birth weight was 12%. Out of 317 anemic mothers, 99 (31%) delivered low birth weight babies. Among those 99 low birth weight babies, 30 (30%) were preterm and 69 (70%) were term babies with the prevalence of low birth weight in anemic mothers being 31%. The correlation between maternal hemoglobin and birth weight was found to be statistically significant. \u0000Conclusions: Despite regular antenatal care, maternal anemia still prevails, affecting neonatal birth weight. There was a statistically significant correlation between maternal hemoglobin and birth weight (p-value <0.0001).","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"13 1","pages":"1756-1759"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75308983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Histomorphological evaluation of non-neoplastic cutaneous disorders 非肿瘤性皮肤疾病的组织形态学评价
Journal of Pathology of Nepal Pub Date : 2020-09-30 DOI: 10.3126/jpn.v10i2.30515
P. Sherpa, A. Amatya
{"title":"Histomorphological evaluation of non-neoplastic cutaneous disorders","authors":"P. Sherpa, A. Amatya","doi":"10.3126/jpn.v10i2.30515","DOIUrl":"https://doi.org/10.3126/jpn.v10i2.30515","url":null,"abstract":"Skin, the largest organ of the body functions as a protective covering to internal viscera; provides a passive protective barrier to fluid loss and mechanical damage; has a sensory contribution and endocrine role of vitamin D synthesis. A spectrum of conditions varying from wrinkles and hair loss, blisters, and rashes to life-threatening malignancies may be consequences of imbalances in factors that maintain the homeostasis amongst skin cells.1 Most skin conditions are diagnosed based on the patient’s history, anatomical distribution, and clinical appearance of the Original Article","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"48 1","pages":"1695-1701"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72867022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laboratory testing COVID-19 实验室检测COVID-19
Journal of Pathology of Nepal Pub Date : 2020-05-29 DOI: 10.3126/jpn.v10i1.29172
R. Baral
{"title":"Laboratory testing COVID-19","authors":"R. Baral","doi":"10.3126/jpn.v10i1.29172","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.29172","url":null,"abstract":"In an ongoing pandemic it is critical to track the virus, understand pathogenesis and epidemiology, manage the cases and suppress transmission that requires effective laboratory testing. In December 2019, a cluster of patients with a novel coronavirus was identified in Wuhan, China. Initially tentatively named 2019 novel coronavirus (2019-nCoV), the virus has now been named SARS-CoV-2 by the International Committee of Taxonomy of Viruses (ICTV). This virus can cause the disease named coronavirus disease 2019 (COVID-19).","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79854921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Undifferentiated carcinoma of pancreas with osteoclastic giant cells along with PanIN in a diabetic female- a case report 女性糖尿病患者胰腺未分化癌伴破骨巨细胞伴PanIN 1例报告
Journal of Pathology of Nepal Pub Date : 2020-05-15 DOI: 10.3126/jpn.v10i1.27297
Lakshmi Unnikrishnan, Noushad Babu PK, Asiq N Sideeque
{"title":"Undifferentiated carcinoma of pancreas with osteoclastic giant cells along with PanIN in a diabetic female- a case report","authors":"Lakshmi Unnikrishnan, Noushad Babu PK, Asiq N Sideeque","doi":"10.3126/jpn.v10i1.27297","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.27297","url":null,"abstract":"Undifferentiated carcinoma of pancreas with osteoclastic giant cells is a rare tumor. The prognosis is slightly better than usual anaplastic carcinoma. It is said to have an epithelial origin. We present a case of 61-year-old female who presented with features of cholangitis and on evaluation found to have pancreatic mass. Pancreatic intraepithelial neoplasia was also present in our case, which is a feature less commonly noted in published literature. ABSTRACT Lakshmi Priya U1, Noushad Babu PK2, Asiq Sideeque1","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"894 1","pages":"1687-1690"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77471858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological analysis of tumours and tumour-like lesions of colon and rectum 结直肠肿瘤及肿瘤样病变的组织病理学分析
Journal of Pathology of Nepal Pub Date : 2020-05-15 DOI: 10.3126/jpn.v10i1.28747
Pramila Vaidhya, R. Adhikari, A. Pant
{"title":"Histopathological analysis of tumours and tumour-like lesions of colon and rectum","authors":"Pramila Vaidhya, R. Adhikari, A. Pant","doi":"10.3126/jpn.v10i1.28747","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.28747","url":null,"abstract":"Results: Out of 125 cases, 32 cases were benign tumours, 36 cases were malignant tumours and 57 cases were tumour like lesions. Most common age range was 51-60 years with mean age of 38 years. Males comprised 76.74% and females 23.26% with ratio of 3:1. Juvenile polyp was the commonest lesion. Among benign tumours, tubular adenoma was the most common (19.2%), adenocarcinoma was most common malignant tumour (25.6%) and juvenile polyp was the most common tumour like lesion (27.2%). Left side was most common side (66.67%) and rectum was the most common site (48.8%).","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"36 1","pages":"1654-1658"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73330388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
COVID-19: a brief review 2019冠状病毒病:简要回顾
Journal of Pathology of Nepal Pub Date : 2020-05-14 DOI: 10.3126/jpn.v10i1.28946
N. Nayak, Arnab Ghosh, D. R. Bhatta, D. Magar
{"title":"COVID-19: a brief review","authors":"N. Nayak, Arnab Ghosh, D. R. Bhatta, D. Magar","doi":"10.3126/jpn.v10i1.28946","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.28946","url":null,"abstract":"In December 2019, Wuhan, in China, became the center of an outbreak of pneumonia of unknown cause In January 2020, a novel coronavirus was identified Later the whole genomic sequence of this novel virus was established The World Health Organization named the disease “COVID-19” and marked it as a pandemic The origin of the virus is still conjectural Studies suggested markedly increased levels of several pro-inflammatory cytokines and chemokines in these patients, which lead to injury to several organs The organ which is most commonly damaged is the lungs On histopathology, lung shows diffuse alveolar damage with hyaline membrane formation The incubation period ranges from 1-14 days The clinical features vary widely, from asymptomatic to multi-organ failure and shock The common clinical features are related to the respiratory system For diagnosis, oropharyngeal/nasopharyngeal swabs should be collected by Dacron swabs under proper precaution and the samples should be collected in viral transport media The viral ribonuclei acid is detected by Real Time-Polymerase Chain Reaction Till now no definite therapy or vaccination is available and the main approach to manage the pandemic is by preventive measures like social distancing, hygiene maintenance, and contact tracing","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"48 1","pages":"1659-1662"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85546367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Malignant Odontogenic tumor: A case report 牙源性恶性肿瘤1例
Journal of Pathology of Nepal Pub Date : 2020-05-14 DOI: 10.3126/jpn.v10i1.27848
B. Ojha, Radha Baral, D. Bajracharya, Sumit Singh
{"title":"Malignant Odontogenic tumor: A case report","authors":"B. Ojha, Radha Baral, D. Bajracharya, Sumit Singh","doi":"10.3126/jpn.v10i1.27848","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.27848","url":null,"abstract":"Ameloblastic carcinoma; malignant odontogenic tumor; Mandible; Malignant odontogenic tumors are rare and represent approximately 1% of all oral malignancies. Ameloblastic Carcinoma is an uncommon malignant odontogenic tumor accounting for 1.5%-2.0% of all odontogenic tumors that can be difficult to differentiate from Ameloblastoma, and can arise directly as an undifferentiated lesion or from a preexisting benign lesion. It is a highly aggressive tumor with rapid growth and a high potential for distant metastasis. The most common site of occurrence is posterior mandible. Here we present a case report of Ameloblastic Carcinoma, relapse case of a benign lesion 15 years after surgery which presented as firm growth in the right mandible for 2 months. ABSTRACT Bidhata Ojha1, Radha Baral1, Dipshikha Bajracharya1, Sumit Singh2","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"36 1","pages":"1679-1682"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82525965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ghost cell odontogenic carcinoma: Role of p53 as predictor of progression 鬼细胞牙源性癌:p53作为进展预测因子的作用
Journal of Pathology of Nepal Pub Date : 2020-05-14 DOI: 10.3126/jpn.v10i1.24763
P. Srivastava, N. Anand, N. Husain
{"title":"Ghost cell odontogenic carcinoma: Role of p53 as predictor of progression","authors":"P. Srivastava, N. Anand, N. Husain","doi":"10.3126/jpn.v10i1.24763","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.24763","url":null,"abstract":"Ghost cell odontogenic carcinoma; Ki 67 proliferation index; p53 Ghost cell odontogenic carcinoma (GCOC) a rare malignant Odontogenic Carcinoma with an unpredictable behaviour presenting with local recurrences and distant metastases, to best of our knowledge about 38 cases have been reported in the past. This is an additional case of GCOC in a 25-year old female presented with a slow-growing mandibular swelling since 9 months with restricted jaw mobility. The CT scan showed an ill-defined osteodestructive lesion in the mandible. The histological examination confirms the diagnoses as a GCOC.","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"31 1","pages":"1675-1678"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81251760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pleural mass in a young male unfolding an uncommon presentation of multiple myeloma 年轻男性胸膜肿块，表现为罕见的多发性骨髓瘤
Journal of Pathology of Nepal Pub Date : 2020-05-14 DOI: 10.3126/jpn.v10i1.26719
P. Bharati, Prajwala Gupta, A. Ahuja, M. Bhardwaj
{"title":"Pleural mass in a young male unfolding an uncommon presentation of multiple myeloma","authors":"P. Bharati, Prajwala Gupta, A. Ahuja, M. Bhardwaj","doi":"10.3126/jpn.v10i1.26719","DOIUrl":"https://doi.org/10.3126/jpn.v10i1.26719","url":null,"abstract":"Multiple myeloma is a malignant proliferation of the plasma cells and can be non-secretory in about 1 to 5 % cases. Pleura based mass lesions are uncommon in myeloma. Herein we report a case of non-secretory multiple myeloma presenting with a pleura based mass in a 40 year old male. Fine needle aspiration cytology with immunohistochemistry played a key role in the diagnosis of this case. ABSTRACT Purnima Bharati1, Prajwala Gupta1, Arvind Ahuja1, Meenakshi Bhardwaj1","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"165 1","pages":"1683-1686"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81708632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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