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Raman spectroscopic characterization of blood plasma of oral cancer 口腔癌患者血浆的拉曼光谱特征
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-12-19 DOI: 10.1109/ICP.2013.6687092
P. Rekha, P. Aruna, Amuthachelvi Daniel, S. W. Prasanna, K. Udayakumar, S. Ganesan, G. Bharanidharan, Balu David
{"title":"Raman spectroscopic characterization of blood plasma of oral cancer","authors":"P. Rekha, P. Aruna, Amuthachelvi Daniel, S. W. Prasanna, K. Udayakumar, S. Ganesan, G. Bharanidharan, Balu David","doi":"10.1109/ICP.2013.6687092","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687092","url":null,"abstract":"Raman Spectroscopy is a versatile technique to probe in to the vibrational or rotational transitions of a molecule and extract complete information about the biochemical composition of the sample under investigation. The metabolic end products of the cell that were released in to the circulating blood would change the biological molecules and thus alter their spectral signatures. Based on this, a pilot study was carried out to discriminate oral cancer patients (n=14) from that of healthy subjects (n=14), using the Raman spectroscopy of blood plasma using Lab RAM HR 800 (HORIBA Jobin Yvon, France) instrument for the spectral range 800- 1800 cm-1. From the spectral profiles of the bio constituents such as protein, amino acids, glucose and lipid, markable difference was observed between the cancer patients and the healthy subjects. Raman peaks corresponding to bio components such as phenylalanine in albumin (939, 1002 cm-1), glucose (1124 cm-1), tryptophan (1205 & 1342 cm-1), amide III (1247 cm-1) and phospholipids (1450 & 1656 cm-1) were different for oral cancer patients from that of healthy subjects. The averaged spectra of cancer patients showed a noticeable blue shift for the peaks corresponding to protein at 1002 cm-1, lipid at 1450 and 1656 cm-1 and a overall decrease in intensity was observed for cancer spectrum. Further, the Raman spectra were analyzed employing the multivariant statistical methods such as principal component analysis (PCA) and linear discriminant analysis (LDA), for the range 800- 1800 cm-1. The results were promising in discriminating blood plasma of oral cancer patients from that of healthy ones.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129147892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Voltage-controlled all-polymer reconfigurable optical power splitter 电压控制的全聚合物可重构光功率分配器
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-12-19 DOI: 10.1109/ICP.2013.6687127
A. Rajandekar, R. Singhal
{"title":"Voltage-controlled all-polymer reconfigurable optical power splitter","authors":"A. Rajandekar, R. Singhal","doi":"10.1109/ICP.2013.6687127","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687127","url":null,"abstract":"A reconfigurable optical 1 × N splitter design is proposed by which incoming optical power can be diverted to any of the N output branches of the device. Tri-cyano-vinylidene-di-phenyl-aminobenzene (TCVDPA) doped SU-8 electro optic polymer is assumed for core material with SU-8 as under and over-clad. Higher-order splitting can be achieved by cascading the 1 × 2 basic power splitter. This paper discuss 1 × 4 optical power splitter which is fully reconfigurable. The Poly(3,4-ethylenedioxythiophene)-Poly(stryene sulfonate) (PEDOT:PSS) electrodes dynamically control the direction in which the power will be diverted. The voltage applied to electrodes determines the splitting ratio at each junction. The design is optimized to achieve diversion of all incoming optical power to a single output node. The output node received around 90 % of incoming power after design optimization.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128390447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Impact of four wave mixing on OSNR of multiwavelength Brillouin-erbium fiber laser 四波混频对多波长布里渊-铒光纤激光器OSNR的影响
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-12-19 DOI: 10.1109/ICP.2013.6687074
N. A. Cholan, M. Al-Mansoori, A. Noor, A. Ismail, M. Mahdi
{"title":"Impact of four wave mixing on OSNR of multiwavelength Brillouin-erbium fiber laser","authors":"N. A. Cholan, M. Al-Mansoori, A. Noor, A. Ismail, M. Mahdi","doi":"10.1109/ICP.2013.6687074","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687074","url":null,"abstract":"An experimental investigation on the optical signal to noise ratio (OSNR) of a multiwavelength Brillouin erbium fiber laser (BEFL) without and with four wave mixing (FWM) effect is demonstrated. The BEFL output before and after an 11 km dispersion compensating fiber is compared in terms of OSNR. It is found that FWM does affect the OSNR of the channels. For the first few channels, the OSNR is lower as compared with the case without FWM effect but for the last few channels, the OSNR is higher.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125636421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Effects of high neutron fluence on the electrical characteristics of InAs quantum dot structures 高中子通量对InAs量子点结构电学特性的影响
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-30 DOI: 10.1109/ICP.2013.6687122
D. A. Fauzi, Nahrul Khair Alang, M. Rashid, N. I. C. Omar, N. Hasbullah, M. R. M. Zin
{"title":"Effects of high neutron fluence on the electrical characteristics of InAs quantum dot structures","authors":"D. A. Fauzi, Nahrul Khair Alang, M. Rashid, N. I. C. Omar, N. Hasbullah, M. R. M. Zin","doi":"10.1109/ICP.2013.6687122","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687122","url":null,"abstract":"The use of InAs quantum dots (QDs) in a well (DWELL) structure as a medium to minimize propagation of neutron induced defects is presented. The DWELL samples and GaAs based commercial diodes were radiated with thermal neutron under maximum fluence of 1.4×l016 neutron/cm2. Based on the current-voltage (I-V) characteristics, it was discovered that the forward bias (FB) leakage current for both devices decreased as an effect of increment in series resistance. In reverse bias (RB), there is significant decrement in leakage current of DWELL samples in the order of 2 orders of magnitude. The RB leakage current of GaAs diode showed similar response as in FB. However, the QD based structures showed less defects compared to the GaAs based diodes.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125862113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination of walsh and Golay codes in modulating the pump light of phase-shift pulse BOTDA sensor 结合walsh码和Golay码调制相移脉冲BOTDA传感器的泵浦光
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-01 DOI: 10.1109/ICP.2013.6687100
M. Zan, K. Yokoyama, T. Horiguchi
{"title":"Combination of walsh and Golay codes in modulating the pump light of phase-shift pulse BOTDA sensor","authors":"M. Zan, K. Yokoyama, T. Horiguchi","doi":"10.1109/ICP.2013.6687100","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687100","url":null,"abstract":"Simulation and experimental results have shown that the combination of two kinds of codes to modulate phase-shift pulse Brillouin optical time domain analysis (PSP-BOTDA) pump pulse for distributed strain measurement provides higher SNR than that of using only one code system, and better spatial resolution than dual Golay codes PSP-BOTDA. In preliminary experiments, 10cm spatial resolution measurement was demonstrated.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127549566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
12-channel tapered SOI-based AWG for CWDM system 用于CWDM系统的12通道锥形soi AWG
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-01 DOI: 10.1109/ICP.2013.6687123
N. Juhari, P. Menon, A. Ehsan
{"title":"12-channel tapered SOI-based AWG for CWDM system","authors":"N. Juhari, P. Menon, A. Ehsan","doi":"10.1109/ICP.2013.6687123","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687123","url":null,"abstract":"A 12-channel Silicon-on-Insulator (SOI)-based Arrayed Waveguide Grating (AWG) with different core width sizes of 1.2 μm and 1.0 μm was designed and characterized for Coarse Wavelength Division Multiplexing (CWDM) System. Beam Propagation Method (BPM) was used to simulate the propagation of light in this device at operating wavelength of 1.491 μm which producing the peak transmission wavelengths ranging from 1391 to 1611 nm. The output spectrum peaks that were obtained from both core widths are close to the CWDM wavelength grid. The core width of 1.2 μm produced the lowest insertion loss and adjacent crosstalk with the values of 4.03 dB and -15.02 dB respectively. Meanwhile, insertion loss of 5.03 dB and adjacent crosstalk of -15.96 dB was obtained from the 1.0 μm core width device where the losses are higher. Hence, the A WG device with larger core width size produced a better insertion loss and adjacent crosstalk.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131356890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Performance comparison of OCDMA codes for quasi-distributed fiber vibration sensing 准分布式光纤振动传感OCDMA码的性能比较
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-01 DOI: 10.1109/ICP.2013.6687084
Ambali Taiwo, S. Seyedzadeh, R. Sahbudin, M. Yaacob, M. Mokhtar, S. Taiwo
{"title":"Performance comparison of OCDMA codes for quasi-distributed fiber vibration sensing","authors":"Ambali Taiwo, S. Seyedzadeh, R. Sahbudin, M. Yaacob, M. Mokhtar, S. Taiwo","doi":"10.1109/ICP.2013.6687084","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687084","url":null,"abstract":"The performance of Khazani Syed (KS) code based fiber vibration measurement for distributed sensing has been investigated. The setup was aimed at implementing quasi distributed vibration sensing with less complexity and optimum performance against Multiple Access Interference. The three sensor points system were compared with existing Optical Orthogonal Code (OOC) and Modified Congruence Code (MQC) in terms of level of power received, supported fiber length and complexity in implementation. Slightly better received power and longer fiber length were demonstrated by the system employing MQC code but a wide gap to OOC code. However, since KS code is implemented with less number of components which tends to reduce the cost and complexity of the system which becomes obvious as the sensor points grow, KS code is recommended for the quasi distributed vibration sensing.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116891544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Tapered multimode fiber sensor for ethanol sensing application 用于乙醇传感的锥形多模光纤传感器
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-01 DOI: 10.1109/ICP.2013.6687137
S. Girei, A. Shabaneh, P. Arasu, Suriati Painam, M. Yaacob
{"title":"Tapered multimode fiber sensor for ethanol sensing application","authors":"S. Girei, A. Shabaneh, P. Arasu, Suriati Painam, M. Yaacob","doi":"10.1109/ICP.2013.6687137","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687137","url":null,"abstract":"Ethanol is a widely used chemical in the industry which can be volatile and flammable. However, the availability of optical sensors for ethanol is still in its maturing stage. In this project, a tapered multimode fiber optic sensor for detection of ethanol with different concentrations in water was developed. The working principle of the sensor is based on absorption spectroscopy in the visible wavelength ranges. The tapered multimode fiber was fabricated using Vytran glass processing workstation to achieve waist diameter and length of 40 μm and 20 mm, respectively. Upon exposure to ethanol concentrations of ranges 5% to 40%, the developed fiber sensor absorbance increases linearly. The sensor shows fast response and recovery as low as 14 s and 27 s, respectively.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"399 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133565327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Direct optimization of Y-branch silicon nitride optical waveguide for evanescent field biosensor 用于瞬变场生物传感器的y分支氮化硅光波导的直接优化
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-01 DOI: 10.1109/ICP.2013.6687081
K. N. Khor, M. Shahimin, F. Adikan
{"title":"Direct optimization of Y-branch silicon nitride optical waveguide for evanescent field biosensor","authors":"K. N. Khor, M. Shahimin, F. Adikan","doi":"10.1109/ICP.2013.6687081","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687081","url":null,"abstract":"Evanescent field had been widely used in bio and chemical sensors. However in most cases, evanescent field is not maximized and consequently produced an unoptimized sensor performance. It is the aim of the paper to optimize the design of 1:2 Y-branch splitter optical waveguide through simulation by using FD-BPM. Y-branch splitter are simulated to optimize the power loss. Width of waveguide and effective angle are manipulated in the power loss optimization. The result shows that evanescent field is maximized at optimized thickness and width. The result suggests that Y -branch splitter with width of 25 μm and effective angle of 6.24° is the best design for evanescent field sensor application with both high sensitivity and signal to noise ratio.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128691367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
A dynamic optically reconfigurable gate array using a blue laser 一种使用蓝色激光的动态光学可重构门阵列
2013 IEEE 4th International Conference on Photonics (ICP) Pub Date : 2013-10-01 DOI: 10.1109/ICP.2013.6687090
Takayuki Kubota, Minoru Watanabe
{"title":"A dynamic optically reconfigurable gate array using a blue laser","authors":"Takayuki Kubota, Minoru Watanabe","doi":"10.1109/ICP.2013.6687090","DOIUrl":"https://doi.org/10.1109/ICP.2013.6687090","url":null,"abstract":"Recently, optically reconfigurable gate arrays (ORGAs), which can support a high-speed dynamic reconfiguration with numerous reconfiguration contexts, have been developed. Although an ORGA is a three-dimensional VLSI, no through-silicon via (TSV) technology or any micro-bump technology is never necessary to produce an ORGA. A three-dimensional ORGA uses only free-optical connections and a volume-type holographic memory technology. Therefore, the yield ratio of ORGAs is so high that ORGAs can easily be produced with no concern related to production variation. In this study, to increase the gate density, a short wavelength laser of 404 nm is applied to ORGA architecture. This paper presents the reconfiguration capabilities of the reconfiguration period and retention time of the photodiode memory architecture of a newly fabricated ORGA-VLSI.","PeriodicalId":308672,"journal":{"name":"2013 IEEE 4th International Conference on Photonics (ICP)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126688653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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