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Aktivitas Daya Hambat Isolat Actinomycetes dengan Lama Fermentasi yang Berbeda terhadap Pertumbuhan Klebsiella pneumoniae 等性动异化活动与气动动发育的长期发酵不同

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2014

Annisa Nur Insani, Meiskha Bahar, Nunuk Nugrohowati, R. Yulianti

{"title":"Aktivitas Daya Hambat Isolat Actinomycetes dengan Lama Fermentasi yang Berbeda terhadap Pertumbuhan Klebsiella pneumoniae","authors":"Annisa Nur Insani, Meiskha Bahar, Nunuk Nugrohowati, R. Yulianti","doi":"10.25077/jka.v11i2.2014","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2014","url":null,"abstract":"Actinomycetes are filamentous, Gram-positive bacteria widely distributed in soil and can produce secondary metabolites useful as antibiotics. The synthesis of secondary metabolites of Actinomycetes is influenced by the growth conditions of each isolate, including the fermentation period. Klebsiella pneumoniae is an opportunistic bacterial pathogen causing lower respiratory tract infection. Objectives: To determined the inhibition activity of Actinomycetes with different fermentation periods against the growth of K.pneumoniae. Methods: Actinomycetes were isolated from soil in Kebun Raya Bogor and grown on Starch Casein Agar (SCA) medium before being fermented in liquid media consisting of 2% of mannitol, 2% of peptone, and 1% of glucose with an incubation time of 6,7, and 8 days. An antibacterial activity test was conducted on Mueller Hinton Agar (MHA) medium using the well diffusion method. Results: The activity of Actinomycetes isolates with fermentation duration of 6,7 and 8 were able to inhibit the growth of K. pneumoniae with an average inhibition zone of 4,46 mm; 4,94 mm; and 5,04 mm, respectively. Actinomycetes' inhibitory mechanism ranges from inhibition of cell wall synthesis to nucleic acid and protein synthesis. One Way ANOVA test showed significant differences between the inhibition zone produced by each fermentation group. Conclusion: Actinomycetes isolates have antibacterial activity against the growth of K. pneumoniae with the highest activity achieved by Actinomycetes with a fermentation time of 8 days.Keywords: Actinomycetes, antibacterial, fermentation, Klebsiella pneumoniae","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48980501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember Jember Cabouth新冠肺炎患者中性粒细胞-淋巴细胞比率（NLR）与降钙素原率（PCT）的关系

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.1999

Sofia Yusnur Rafida, Hairrudin Hairrudin, Muhammad Hasan

{"title":"Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember","authors":"Sofia Yusnur Rafida, Hairrudin Hairrudin, Muhammad Hasan","doi":"10.25077/jka.v11i2.1999","DOIUrl":"https://doi.org/10.25077/jka.v11i2.1999","url":null,"abstract":"The neutrophil-to-lymphocyte ratio (NLR) and Procalcitonin (PCT) are biomarkers that represent inflammatory activity and immune status as predictors for the prognosis of COVID-19 patients. NLR values and PCT levels are positively correlated with the severity of COVID-19, but the relationship between the two biomarkers is unclear. Objectives: To analyzed the correlation between NLR values and PCT levels in COVID-19 patients in Jember Regency. Methods: This cross-sectional analytic observational study, conducted from March to April 2022, took data from 444 confirmed COVID-19 patients at the Jember Clinic Plantation Hospital. Secondary data were obtained from medical records of inpatients for the period January–December 2021. Results: The average NLR value was 8.58, while the average PCT level was 0.43 ng/mL. The results of the Spearman Correlation Analysis showed a positive correlation between NLR values and PCT levels in COVID-19 patients in the Jember Regency with a p-value = 0.00 and a moderate degree of correlation with an r count of 0.41. Conclusion: There is a positive correlation between NLR values and PCT levels for COVID-19 patients in Jember Regency. It is necessary to carry out routine NLR and PCT examinations to consider predictors of disease severity and prognosis in COVID-19 patients.Keywords: COVID-19, NLR, PCT","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45552725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risiko Perdarahan Saluran Cerna pada Pasien COVID-19 berdasarkan Jenis Obat Antivirus di Rumah Sakit Umum Pusat Dr. M. Djamil Padang 患者COVID-19的Cerna渗透性出血风险，基于M. Djamil Padang将军医院的一种抗病毒药物

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2042

Arnelis Arnelis, Saptino Miro, Nasrul Zubir, Vesri Yoga, Andry Kurniawan, Alexander Kam, Abdul Alim Rahimi, Jersivindo Ranazeri, R. Fahrurozi

{"title":"Risiko Perdarahan Saluran Cerna pada Pasien COVID-19 berdasarkan Jenis Obat Antivirus di Rumah Sakit Umum Pusat Dr. M. Djamil Padang","authors":"Arnelis Arnelis, Saptino Miro, Nasrul Zubir, Vesri Yoga, Andry Kurniawan, Alexander Kam, Abdul Alim Rahimi, Jersivindo Ranazeri, R. Fahrurozi","doi":"10.25077/jka.v11i2.2042","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2042","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) has become a global pandemic to date. Some studies reported gastrointestinal tract (GIT) bleeding occurs in several patients hospitalized with COVID-19. Medications known to be associated with an increased risk of GIT bleeding were not associated with GIT bleeding in COVID-19 patients. Objectives: To examined the risk of gastrointestinal tract (GIT) bleeding in COVID-19 patients based on antiviral drugs at Dr. M. Djamil General Hospital Padang. Methods: A nested cohort study was conducted in Dr. M. Djamil General Hospital Padang from May until October 2021. All COVID-19 patients who received antiviral drugs with GIT bleeding with onset days 0 - 7 were included. COVID-19 was confirmed by RT-PCR swab. Data entry and analysis were conducted by computerized. Results: 30 patients were involved in this study. 43,3% COVID-19 Moderate stage and 56,7% Severe stage. 63,3% were treated with remdesivir and 36,7% were treated with favipiravir. Onset on GIT tract bleeding at day 4 (23,3%), day 5 (26.7%), day 6 (30%), and day 7 (20%). The Chi-square test to determine the factors associated with GIT bleeding in COVID-19 patients including COVID-19 severity, type of antiviral drugs, anticoagulant, and corticosteroid revealed that none of all potential factors above related to GI bleeding. Conclusion: The type of antiviral drugs was not related to GIT bleeding in COVID-19 patients.Keywords: antiviral drugs, COVID-19, gastrointestinal tract bleeding","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41389965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pengaruh Suplementasi Saccharomyces boulardii terhadap Kejadian Diare pada Balita 布拉地底组织对幼儿腹泻事件的持续影响

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2015

Winda Wahyu Pratiwi, Dwi Sarbini

{"title":"Pengaruh Suplementasi Saccharomyces boulardii terhadap Kejadian Diare pada Balita","authors":"Winda Wahyu Pratiwi, Dwi Sarbini","doi":"10.25077/jka.v11i2.2015","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2015","url":null,"abstract":"Diarrhea is a disease that occurs due to viral or bacterial infection in the digestive tract system. Signs of diarrhea are the stool becomes liquid and the frequency of bowel movements is more than three times a day and is accompanied by blood and mucus or only mucus. Saccharomyces boulardii is a probiotic yeast with proven medicinal benefits, especially in the gastrointestinal tract and antibiotic booster. Objectives: To describe the effect of Saccharomyces boulardii supplementation on the incidence of diarrhea in toddlers. Methods: Literature review method with 11 articles (2011-2021) and the keywords used are \"Saccharomyces boulardii, diarrhea, toddler\". Journal search with Google scholar, Scopus and Pubmed. Reputable journals SINTA S1 with 1, Scopus Q1 with 3 articles, Q2 with 2 articles, Q4 with 5 articles. Results: The results of the literature review showed that as many as ten articles (90.9%) stated that Saccharomyces boulardii supplementation had a significant effect on reducing the duration of diarrhea in children under five. In addition to the effect on the duration of diarrhea in toddlers, there are also 5 articles (45.4%) stating that there is an effect on reducing the frequency of diarrhea in toddlers on the second day after supplementation with Saccharomyces boulardii. Conclusion: There is an effect of Saccharomyces boulardii supplementation on reducing the duration and frequency of diarrhea in toddlers.Keywords: diarrhea, toddler, Saccharomyces boulardii","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48378359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue 蓝体淋巴细胞与c反应蛋白水平的关系支持登革热出血热的诊断

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2032

Ayu Safitri Sholihah, I. Danuyanti, Siti Zaetun, Pancawati Ariami, Ersandhi Resnhaleksmana

{"title":"Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue","authors":"Ayu Safitri Sholihah, I. Danuyanti, Siti Zaetun, Pancawati Ariami, Ersandhi Resnhaleksmana","doi":"10.25077/jka.v11i2.2032","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2032","url":null,"abstract":"Dengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. Objectives: To analyzed the correlation of the number of Blue Plasma Lymphocytes with C-Reactive Protein (CRP) levels in Dengue Hemorrhagic Fever patients. Methods: This study was analytical observational research with a cross-sectional design. The sample used was a patient diagnosed with DHF with a positive Nonstructural protein 1 (NS1) or Rapid Diagnostic Test (RDT) IgG/IgM result. The data was collected and analyzed using Spearman's rank statistical test. Results: The average number of Blue Plasma Lymphocytes in positive samples was 8%, with the number of negative results, namely 4 (13.33%) samples and 26 (86.67%) samples with positive Blue Plasma Lymphocyte results. The average level of C–Reactive Protein in the positive samples was 29.36 mg/L, with results that had normal levels were 11 (36.67%) samples and 19 (63.33%) samples with abnormal C-Reactive Protein levels. Spearman's Rank statistical test results obtained a value of p = 0.000 < 0.05, indicating a correlation between the number of Blue Plasma Lymphocytes and C–Reactive Protein levels in Dengue Hemorrhagic Fever patients. Conclusion: The more Blue Plasma Lymphocytes, the higher C–Reactive Protein levels in Dengue Hemorrhagic Fever.Keywords: blue plasma lymphocytes, C–reactive protein, dengue hemorrhagic fever","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45626753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hubungan Albuminuria dan Laju Filtrasi Glomerulus pada Pasien Diabetes Melitus Tipe 2 yang Tidak Terkontrol 2型糖尿病患者蛋白尿与肾小球滤过层的关系

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.1994

Vinny Vania Parinding, M. I. Ilmiawan, Iit Fitrianingrum, Heru Fajar Trianto, M. Mardhia

{"title":"Hubungan Albuminuria dan Laju Filtrasi Glomerulus pada Pasien Diabetes Melitus Tipe 2 yang Tidak Terkontrol","authors":"Vinny Vania Parinding, M. I. Ilmiawan, Iit Fitrianingrum, Heru Fajar Trianto, M. Mardhia","doi":"10.25077/jka.v11i2.1994","DOIUrl":"https://doi.org/10.25077/jka.v11i2.1994","url":null,"abstract":"Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Patients with diabetes mellitus require optimal glycemic control. Poorly controlled diabetes mellitus is at risk for complications, such as diabetic nephropathy. Diabetic nephropathy is characterized by albuminuria and can lead to decreased Glomerular Filtration Rate (GFR). Objectives: To determined the relationship between albuminuria and GFR in a patient with poorly controlled type 2 diabetes mellitus. Methods: This research was conducted at the Pontianak Branch of Prodia Health Clinic Laboratory in March 2021, using secondary data of laboratory examination results from DM patients in the 2020 period. This research was observational analytics with a cross-sectional approach. The number of samples that comply with the research criteria was 273 people. Bivariate analysis using Spearman’s correlation test. Results: Spearman's correlation test results showed significance (p=0.001) and correlation coefficient (r=0.209). Conclusion: Albuminuria and GFR in a patient with poorly controlled type 2 diabetes mellitus are significantly and positively correlated.Keywords: albuminuria, poorly controlled type 2 diabetes mellitus, glomerular filtration rate","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47389961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kombinasi Injeksi Triamsinolon Asetat Intralesi dan Propanolol Oral pada Kasus Hemangioma Kapiler Palpebra 醋酸三胺酮注射和口腔前丙戊酸造血血管血管管路

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2082

Mardijas Efendi, Hendriati Hendriati, A. Rahman, Muhammad Fadhil Rahmadiansyah

{"title":"Kombinasi Injeksi Triamsinolon Asetat Intralesi dan Propanolol Oral pada Kasus Hemangioma Kapiler Palpebra","authors":"Mardijas Efendi, Hendriati Hendriati, A. Rahman, Muhammad Fadhil Rahmadiansyah","doi":"10.25077/jka.v11i2.2082","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2082","url":null,"abstract":"Capillary hemangioma is a benign tumor developed from the abnormal proliferation of blood vessels. This tumor appears on eyelids and orbit. Around 75% of hemangioma resolves spontaneously in the first 4-5 years of life. Intervention is needed in hemangioma that obstructs the visual axis. It has been reported that a two-year-old girl came to Polyclinic with a mass on the left superior eyelid 1,5 years ago. At first, the left superior eyelid looked puffy, then developed slowly until it covered the left eye. On the examination of the left eye, visual acuity assessment was hard to perform. Mass in superior palpebral was 8mm x 8mm x 8mm, reddish colored (different with adjacent skin), consistency supple, mobile, painful (-), edema (+), horizontal palpebral fissure (FPH) 30 mm, vertical palpebral fissure (FPV) 0 mm. CT scan showed suspected hemangioma. The patient was diagnosed with capillary hemangioma and given an injection of triamcinolone acetate intralesional and oral propranolol under the supervision of a pediatrician. Significant clinical improvement was observed after 40 days of injection, where the mass was resolved completely. The FPV and FPH of the left eye had improved to 9 mm and 30 mm, respectively, with the patient finally able to follow the object. The combination of intralesional triamcinolone acetate and oral propranolol in this case is quite effective in providing complete resolution of capillary hemangioma.Keywords: capillary hemangioma, triamcinolone acetate injection, propanolol","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69196873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analisis Kandungan Metabolit Sekunder, Antioksidan dan Uji Aktivitas Antibakteri Minuman Tradisional Serbat Khas Kalimantan Barat dengan Variasi Komposisi dan Lama Perendaman 次生代谢产物含量分析、抗氧化剂及抗菌活性试验

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.1925

Syarifah Nyrs Asseggaf, Mistika Zakiah, Ridha Ulfah

{"title":"Analisis Kandungan Metabolit Sekunder, Antioksidan dan Uji Aktivitas Antibakteri Minuman Tradisional Serbat Khas Kalimantan Barat dengan Variasi Komposisi dan Lama Perendaman","authors":"Syarifah Nyrs Asseggaf, Mistika Zakiah, Ridha Ulfah","doi":"10.25077/jka.v11i2.1925","DOIUrl":"https://doi.org/10.25077/jka.v11i2.1925","url":null,"abstract":"Serbat drink is a traditional drink typical of the Malay of West Kalimantan made from plant spices usually served in the Saprahan tradition. Serbat drinks are widely circulated among the public because, empirically, they are useful for health problems, one of which is to treat diarrhea. Objectives: To analyzed the content of secondary metabolites, antioxidant activity, and antibacterial activity of serbat drink on the growth of Escherichia coli bacteria which were known from the presence or absence and measurement of the length of the inhibition zone (the clear area around the disc) with the positive control, namely ciprofloxacin, and negative control, namely distilled water. Methods: The plant spices used in this research include cardamom, cloves, star anise, cinnamon, pandan leaves, sappan wood, anise, and ginger. Serbat drink was made in 3 variations, namely composition A, composition B, and composition C. The three composition variations were carried out for two soaking times, namely 15 minutes and 540 minutes. This study used the thin-layer chromatography (TLC) method for phytochemical screening, the DPPH (2,2-diphenyl-1-pikrilhidrazil) method for examination of antioxidant activity, and Escherichia coli bacteria cultured in 3 agar and tested using the disc diffusion method (Kirby-Bauer) to determine its antibacterial activity. Results: The secondary metabolites contained in each serbat water sample, antioxidant activity from strongest to weakest among the serbat samples, and the absence of visible inhibition zones. Conclusion: Serbat drink does not have antibacterial activity against Escherichia coli.Keywords: secondary metabolites, serbat drink, variations in composition, variations in the soaking time","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43402490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insidensi Bayi Berat Lahir Rendah pada Spektrum Plasenta Akreta di Rumah Sakit Dr Hasan Sadikin Bandung 哈桑·萨德金·万隆医院阿克雷塔胎盘谱下的低出生的婴儿

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2063

Yuktiana Kharisma, Hasrayati Agustina, Sri Suryanti, Birgitta M. Dewayani, B. S. Hernowo

{"title":"Insidensi Bayi Berat Lahir Rendah pada Spektrum Plasenta Akreta di Rumah Sakit Dr Hasan Sadikin Bandung","authors":"Yuktiana Kharisma, Hasrayati Agustina, Sri Suryanti, Birgitta M. Dewayani, B. S. Hernowo","doi":"10.25077/jka.v11i2.2063","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2063","url":null,"abstract":"Low birth weight (LBW) babies are closely related to infant morbidity, stunted growth and cognitive development, and chronic diseases. Placenta accreta spectrum (PAS) is a condition that complicates pregnancy and is closely related to low birth weight. Objectives: To determined the incidence of LBW in mothers with SPA at the hospital Dr. Hasan Sadikin Bandung. Methods: A descriptive observational study involving 71 cases of SPA in hospitals Dr. Hasan Sadikin Bandung, period 2016-2020, which has met the inclusion and exclusion criteria. SPA cases were divided into three groups: placenta accreta, increta, and percreta. In each SPA group, the incidence of LBW was evaluated. Results: 46.5% (33/71 cases of PAS) had low birth weight, while 53.5% (38/71 cases of PAS) had normal birth weight babies. The placenta accreta and percreta groups were dominated by normal birth weight infants [(18/31 cases), (5/9 cases)], while the placenta increta group was dominated by low birth weight infants (16/31 cases). The LBW category is divided into Extremely Low Birth Weight (ELBW), Very Low Birth Weight (VLBW), and LBW. In placenta accreta, there were 2 ELBW and VLBW infants, and 9 LBW infants. In the placenta increta, there are 3 ELBW and VLBW, and 10 LBW. In the placenta percreta, there were 1 ELBW and 3 LBW, while VLBW was not found in the placenta percreta. Conclusion: The incidence of LBW is found in almost half the population of SPA cases in hospitals. DR. Hasan Sadikin in the 2016-2020 period.Keywords: low birth weight, placenta accreta spectrum","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47367609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perbandingan Jumlah Trombosit pada Pasien COVID-19 dengan Kadar Glukosa yang Berbeda 新冠肺炎不同血糖率患者血小板计数的比较

Jurnal Kesehatan Andalas Pub Date : 2022-12-26 DOI: 10.25077/jka.v11i2.2000

Imanta Alifia Octavira, Agrijanti Agrijanti, Lalu Srigede, Siti Zaetun

{"title":"Perbandingan Jumlah Trombosit pada Pasien COVID-19 dengan Kadar Glukosa yang Berbeda","authors":"Imanta Alifia Octavira, Agrijanti Agrijanti, Lalu Srigede, Siti Zaetun","doi":"10.25077/jka.v11i2.2000","DOIUrl":"https://doi.org/10.25077/jka.v11i2.2000","url":null,"abstract":"Hyperglycemia has increased arachidonic acid thromboxane which is an effective ingredient in platelet activation. Thrombocytopenia in COVID-19 patients occurs through a variety of mechanisms, such as uncontrolled production of cytokines destroying bone marrow progenitor cells, direct inhibition of hematopoiesis viral infection of the bone marrow, increase in autoantibodies and immune complexes that cause platelet destruction, and lung injury that causes platelet aggregation and consumption of platelets so that platelets in the circulation are reduced. Objectives: To analyzed the ratio of platelet counts in COVID-19-positive patients who had different blood glucose levels. Methods: This research used secondary data, with types of analytical observational research as well as comparative study approaches. Statistical tests were conducted using an independent samples t-test with a confidence level of 95%. Results: The average platelet count was normal, but a low platelet count of 3.30% was obtained with normal blood glucose levels and a high platelet count of 2.20% with normal blood glucose levels, with a significance value of platelet count with normal blood glucose levels of 0.790 and platelet counts with blood glucose levels above normal which is 0.791 with a confidence level of 95%. Conclusion: There was no significant difference between the platelet count in COVID-19 patients with normal and above normal blood glucose levelsKeywords: blood glucose, platelets, COVID-19","PeriodicalId":30736,"journal":{"name":"Jurnal Kesehatan Andalas","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45206331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0