{"title":"Data mining and knowledge discovery from membrane proteins","authors":"J.Y. Yang, M. Qu Yang, O. Ersoy","doi":"10.1109/CIMA.2005.1662360","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662360","url":null,"abstract":"Many of the central questions in bioinformatics relate to protein structure and function. We are mainly be concerned with three problems: identifying transmembrane segments in proteins, distinguishing disordered from ordered regions, and determining protein function from sequence information. In order to deal effectively with these problems, we have conducted an in-depth analyses of the physiochemical properties of the amino acids that make up proteins and the amino acid compositions of the various types of proteins. We approach the above questions from a machine learning perspective","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128837646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Holonic multi-agent system complemented by human disease ontology supporting biomedical community","authors":"M. Hadzic, E. Chang","doi":"10.1109/CIMA.2005.1662307","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662307","url":null,"abstract":"The medical milieu is an open environment characterized by a variety of distributed, heterogeneous and autonomous information resources. Coordination, cooperation and exchange of information is important to the medical community. This paper presents an ontology-based holonic multi-agent system that combines the advantages of the holonic paradigm with multi-agent system technology and ontology design, in order to realize a highly reliable, adaptive, scalable, flexible and robust diagnostic system for diseases. We design a new ontology, called generic human disease ontology (GHDO), for the representation of knowledge regarding human diseases. The concepts of the GHDO ontology are organized into the following four dimensions: types, symptoms, causes and treatments of human diseases. The holonic multi-agent system uses this common GHDO ontology for purpose of query formulation, information retrieval and information integration. This intelligent dynamic system provides opportunities to collect information from multiple information resources, to share data efficiently and to integrate and manage scientific results in a timely manner. We believe such a technique is expected to become the norm once existing resources (e.g. disease databases) will have become unlocked semantically through annotation with a shared ontology","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123288954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Image fusion with perfect reconstruction DFT/RDFT filter banks and DWT","authors":"O. Ersoy","doi":"10.1109/CIMA.2005.1662324","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662324","url":null,"abstract":"We present a perfect reconstruction DFT/RDFT filter bank algorithm and its application in image fusion in comparison to and in conjunction with the DWT method. In order to achieve perfect reconstruction, it is necessary to modify the input signal slightly with an invertible transformation only when the number of data points is divisible by 4. In image fusion application investigated, a SPOT panchromatic image is fused with a corresponding SPOT multispectral image with three bands. For this purpose, the approximation subband of the multispectral image is merged with the detail subbands of the panchromatic image. The fused image is recovered from the subband images by the perfect reconstruction algorithm. The RDFT and DWT results are comparable. By fusing the two together with another algorithm, better results are obtained","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126280765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automatic detection of pulmonary arteries and assessment of bronchial dilatation in HRCT images of the lungs","authors":"Sata Busayarat, T. Zrimec","doi":"10.1109/CIMA.2005.1662325","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662325","url":null,"abstract":"Bronchial dilatation is one of the most important direct signs for the diagnosis of bronchiectasis in high-resolution CT images of the lung. The assessment of the dilatation is done by comparing the size of the bronchus and accompanying artery. Previous work has shown that the success of an automatic bronchial dilatation detection method is limited by high measurement error rate of small bronchi and arteries. This paper presents a new method for automatic detection of accompanying arteries and assessment of bronchial dilatation. A knowledge-guided template matching is used to approximately locate the accompanying artery of a bronchus. A seeded region growing, with leaking prevention and correction, is used to precisely segment the artery. Bronchus-artery lumen area ratio (LAR) and their shortest diameter ratio (SDR) are used to compare the sizes of a bronchus and the accompanying artery. Machine learning is used to determine the suitable severity thresholds for different sizes of bronchi. The method was evaluated using 324 images from 64 patient studies. The results were compared with manual identification and classification, which were verified by an experienced radiologist. The method achieved 90% and 82% accuracies for artery detection and dilatation assessment, respectively","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116692413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A, neural learning approach for tlime-varying frequency estimation of distorted harmonic signals in power systems","authors":"D. Abdeslam, P. Wira, J. Mercklé, D. Flieller","doi":"10.1109/CIMA.2005.1662367","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662367","url":null,"abstract":"In this paper, we consider the problem of estimating the frequency of a sinusoidal signal whose amplitude and frequency could be either constant and time-varying. We present an artificial neural network approach for the on-line estimation of the signal frequency. The neural network architecture and learning is formulated based on an original decomposition of the signal to estimate. We show that the neural estimator can be implemented using hardware technologies and can be efficiently be compared to conventional frequency estimation algorithms. The problem of detecting frequency variations in a power system is addressed and the results show that the neural frequency estimator is efficient. Simulation and experimental examples on a real-time platform are included to show the performance in terms of both estimation and detection","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134275179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The prediction of bankruptcy using fuzzy classifiers","authors":"R. Nogueira, S. Vieira, J. Sousa","doi":"10.1109/CIMA.2005.1662315","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662315","url":null,"abstract":"Real-world databases are highly susceptible to noisy, missing, and inconsistent data due to their typically huge size, which is a prevailing problem in data analysis. The easiest way to handle such data sets in classification is to discard data with missing and extreme values. Since this complete case approach may result in a loss of valuable information and reduced data set size, preprocessing techniques are used in this paper. These techniques include data cleaning, data transformations and data reduction. A new feature selection for data reduction is introduced, which uses the fast fuzzy clustering algorithm in classification problems. The experiments show the advantages of the proposed methods for data preprocessing in a real world problem: the prediction of bankruptcy. The data set used in this study has missing values and extreme values. The data set also presents a much smaller bankruptcy class than the not bankruptcy class","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132057212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Valve health monitoring with wavelet transformation and neural networks (WT-NN)","authors":"I. Tansel, J. Perotti, A. Yenilmez, P. Chen","doi":"10.1109/CIMA.2005.1662337","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662337","url":null,"abstract":"Servovalves are one of the most important components of the complex machinery of space exploration. They have to be at the perfect condition for safe and efficient operation of very valuable complex machines. In this paper, use of wavelet transformation (WT) and adaptive resonance theory 2 (ART2) type self learning neural network (NN) combination is proposed for detection of defective valves. The current signature of the energization stage of the valve was encoded by using the WT. ART2 classified the approximation coefficients of the WT. WT-NN classified all the normal valve data in single category and assigned new categories to the data of defective valves as long as the vigilance was selected properly. WT-NN combination was found an effective alternative to customized diagnostic software if the operating conditions change drastically","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128847172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automated learning of genome sequences by computational intelligence","authors":"M.Q. Yang, J.Y. Yang, Zuojie Luo, O. Ersoy","doi":"10.1109/CIMA.2005.1662321","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662321","url":null,"abstract":"Advent of high-throughput sequencing technology has led to an exploration of DNA sequence data available. Structures and functions of protein sequence coded for by sequenced genomes remain largely unknown. Automated identification of protein functions and interactions have been largely relying on the known 3D structures or sequence homologues. In particular, intrinsic unstructured or disordered proteins lack specific 3D structures and are unconsented during evolution, but play central roles in diseases characterized by protein misfolding and aggregation. Can we assign protein functions to sequences without relying on 3D structures, to provide useful information for the study of diseases? We developed machine learning techniques to rapidly assess protein functions from sequences. The problem of assigning functional classes to proteins is complicated by the fact that a single protein can participate in several different pathways and thus can have multiple functions (due to complex interactions among proteins). It follows that the instances in the resulting classification problem can carry multiple class labels. We have developed a tree-based classifier that capable of classifying multiply-labeled data and gained an insight into the multi-functional nature of proteins. The algorithm has been used with ensemble methods in connection with other computational intelligence to form a committee machine. Results have been compared favorably to those achieved algorithms such as decision trees and support vector machines","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127051376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hierarchical topological clustering learns stock market sectors","authors":"K. Doherty, R. Adams, N. Davey, W. Pensuwon","doi":"10.1109/CIMA.2005.1662299","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662299","url":null,"abstract":"The breakdown of financial markets into sectors provides an intuitive classification for groups of companies. The allocation of a company to a sector is an expert task, in which the company is classified by the activity that most closely describes the nature of the company's business. Individual share price movement is dependent upon many factors, but there is an expectation for shares within a market sector to move broadly together. We are interested in discovering if share closing prices do move together, and whether groups of shares that do move together are identifiable in terms of industrial activity. Using TreeGNG, a hierarchical clustering algorithm, on a time series of share closing prices, we have identified groups of companies that cluster into clearly identifiable groups. These clusters compare favourably to a globally accepted sector classification scheme, and in our opinion, our method identifies sector structure clearer than a statistical agglomerative hierarchical clustering method","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125122408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surface EMG signals pattern recognition utilizing an adaptive crosstalk suppression preprocessor","authors":"K. Nazarpour","doi":"10.1109/CIMA.2005.1662327","DOIUrl":"https://doi.org/10.1109/CIMA.2005.1662327","url":null,"abstract":"This paper proposes utilization of a least mean square (LMS) based finite impulse response (FIR) adaptive filter block, before conventional surface electromyogram (sEMG) signal pattern classification schemes. This novel configuration suppresses the sEMG between channels crosstalk. In this study, the sEMG signals are detected from the biceps and triceps brachii muscles to identify four primitive motions, i.e., elbow flexion/extension and forearm supination/pronation. A multi layer perceptron (MLP) classifies the two time domain feature vectors that are extracted from raw and preprocessed sEMG signals, respectively. Although the implementation of an adaptive filter increases computational complexity, significant advances in sEMG pattern classification has been achieved","PeriodicalId":306045,"journal":{"name":"2005 ICSC Congress on Computational Intelligence Methods and Applications","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131830547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}