Data mining and knowledge discovery from membrane proteins

Abstract

Many of the central questions in bioinformatics relate to protein structure and function. We are mainly be concerned with three problems: identifying transmembrane segments in proteins, distinguishing disordered from ordered regions, and determining protein function from sequence information. In order to deal effectively with these problems, we have conducted an in-depth analyses of the physiochemical properties of the amino acids that make up proteins and the amino acid compositions of the various types of proteins. We approach the above questions from a machine learning perspective