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Administration of Levetiracetam via Subcutaneous Infusion for Seizure Control in the Palliative Care Setting: A Narrative Review. 在姑息治疗环境中通过皮下注射左乙拉西坦控制癫痫发作:叙述性综述。
IF 2
Pharmacy Pub Date : 2024-08-16 DOI: 10.3390/pharmacy12040125
Fern Beschi, Rachel Hughes, Jennifer Schneider
{"title":"Administration of Levetiracetam via Subcutaneous Infusion for Seizure Control in the Palliative Care Setting: A Narrative Review.","authors":"Fern Beschi, Rachel Hughes, Jennifer Schneider","doi":"10.3390/pharmacy12040125","DOIUrl":"10.3390/pharmacy12040125","url":null,"abstract":"<p><p>This narrative review aims to summarise the information available on the use of subcutaneous (SC) levetiracetam (LEV) in the adult palliative care setting using clinical texts, databases, journals, and grey literature. A search strategy utilising Embase, Medline CINALH and Cochrane databases, as well as Google Scholar, was conducted with the mapped search terms \"levetiracetam\", \"subcutaneous\" and \"palliative\". LEV intravenous (IV) proprietary products are used subcutaneously, including as continuous subcutaneous infusions (CSCIs), in the adult palliative care setting. The total LEV daily dose ranged from 250 mg to 5000 mg and LEV was administered with various diluents at varying volumes. The data identified a clinical desire to mix LEV with other medications; however, the current evidence on combination compatibility is observational only and drug stability in combinations is lacking. The majority of information in the literature on SC LEV use is based on case reports and retrospective audits. Case reports, whilst at times offering more clinical detail, represent specific circumstances not necessarily applicable to a larger patient cohort. The findings of retrospective audits are limited by the documentation and detail reported at the time of patient care that may not be designed for data collection.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining Delineated Competencies within Blended Hospital/Health System Pharmacy and General Medicine Advanced Pharmacy Practice Experiences. 在混合式医院/卫生系统药房和全科医学高级药房实践经验中检验划定的能力。
IF 2
Pharmacy Pub Date : 2024-08-13 DOI: 10.3390/pharmacy12040124
Jennifer L Prisco, Yulia A Murray, Tewodros Eguale, Jennifer D Goldman
{"title":"Examining Delineated Competencies within Blended Hospital/Health System Pharmacy and General Medicine Advanced Pharmacy Practice Experiences.","authors":"Jennifer L Prisco, Yulia A Murray, Tewodros Eguale, Jennifer D Goldman","doi":"10.3390/pharmacy12040124","DOIUrl":"10.3390/pharmacy12040124","url":null,"abstract":"<p><p>In the United States, Doctor of Pharmacy (PharmD) programs are required to provide advanced pharmacy practice experiences (APPEs) in the core inpatient rotation areas of hospital/health system pharmacy and inpatient general medicine patient care. Colleges and Schools of Pharmacy (C/SOPs) nationwide are increasingly utilizing blended or longitudinal APPE models to offer experiential opportunities; however, there is a gap in the literature to support programs with delineating rotation-specific competencies when integrating two or more rotations together. Utilizing a survey instrument, PharmD students at two C/SOPs reported their onsite inpatient rotation sub-competency activities achieved within the four competency areas of Hospital/Health Pharmacy Systems, Medication Safety and Quality, Clinical Applications, and Professional Practice, which are listed in Appendix C of the 2016 Accreditation Council for Pharmacy Education Standards Guidance Document. Unpaired two-sample <i>t</i>-tests were performed to compare proportions of sub-competency activity occurrence in the two rotation settings. In total, 168 students reported inpatient activities related to the four competency areas, with 95-100% reporting their involvement in one or more sub-competency opportunities within each area. Of the 26 sub-competencies compared, 73% significantly facilitated the development of competency to a greater extent for one APPE inpatient rotation type over the other (<i>p</i> < 0.05). The findings can be utilized by C/SOPs to support the delineation of rotation-specific competencies when blending inpatient experiential opportunities.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11359137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medication Reconciliation as Part of Admission Management-A Survey to Improve Drug Therapy Safety in a Urology Department. 作为入院管理一部分的药物调节--一项旨在提高泌尿科药物治疗安全性的调查。
IF 2
Pharmacy Pub Date : 2024-08-06 DOI: 10.3390/pharmacy12040122
Yvonne Remane, Luisa Pfeiffer, Leonie Schuhmann, Annett Huke, Jens-Uwe Stolzenburg, Thilo Bertsche
{"title":"Medication Reconciliation as Part of Admission Management-A Survey to Improve Drug Therapy Safety in a Urology Department.","authors":"Yvonne Remane, Luisa Pfeiffer, Leonie Schuhmann, Annett Huke, Jens-Uwe Stolzenburg, Thilo Bertsche","doi":"10.3390/pharmacy12040122","DOIUrl":"10.3390/pharmacy12040122","url":null,"abstract":"<p><p>Complete medication reconciliation during hospital admission is the rationale for further treatment decisions. A consecutive, controlled intervention study was conducted to assess discrepancies in medication reconciliation performed by nurses of the Urology Department compared to the Best Possible Medication History (BPMH) established by pharmacists. This study included pre-intervention (control group, CG), nursing training as a pharmaceutical intervention, and post-intervention (intervention group, IG) groups. The discrepancies were classified as \"Missing\" (not recorded but taken), \"Added\" (additionally recorded) \"Strength\" (incorrect documented dosage), \"Intake\" (incorrect intake time/schedule), \"Double\" (double prescription), and \"Others\" (no clear assignment). Additionally, high-risk drug subgroup discrepancies were particularly prevalent and were evaluated. Training success was compared concerning discrepancies in the CG and IG. Generally, the percentage of discrepancies per patient found was lower in the IG than in the CG (78.1% vs. 87.5%, significantly). The category most identified was \"Missing\" (IG, 33.3% vs. CG, 35.2%). Overall, a discrepancy of 7.4% each (discrepancies: IG, 27 vs. CG, 38) was determined for high-risk drugs while \"Missing\" occurred (77.8% vs. 52.6%, out of 7.4%). Despite nursing training only partially reducing discrepancies, the implementation of medication reconciliation using BPMH by pharmacists could improve the process, especially for high-risk drugs.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11359777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Student Stress, Coping, and APPE Readiness at Two Public Institutions before and during the Pandemic. 两所公立院校在大流行之前和期间的学生压力、应对和 APPE 准备情况。
IF 2
Pharmacy Pub Date : 2024-08-05 DOI: 10.3390/pharmacy12040121
Tram B Cat, Shareen Y El-Ibiary, Kelly C Lee
{"title":"Student Stress, Coping, and APPE Readiness at Two Public Institutions before and during the Pandemic.","authors":"Tram B Cat, Shareen Y El-Ibiary, Kelly C Lee","doi":"10.3390/pharmacy12040121","DOIUrl":"10.3390/pharmacy12040121","url":null,"abstract":"<p><p>The coronavirus disease 2019 (COVID-19) pandemic significantly impacted pharmacy students' education and well-being. The primary aim of this study was to evaluate the effects of the pandemic on students' perceived stress by comparing third- and fourth-year students from the pre-pandemic Class of 2019 with mid-pandemic Class of 2021 at two public institutions. Secondary aims were to evaluate the pandemic effects on students' academic and professional development skills and practice readiness. The Perceived Stress Scale (PSS) and the Brief Coping Orientation to Problems Experienced (COPE) scale were used to measure student well-being. Students' self-rated problem-solving, time management, and study skills were used to measure their academic and professional development; practice readiness was measured using students' self-rated confidence levels. PSS scores were significantly higher in mid-pandemic than pre-pandemic students, and the Brief COPE avoidant coping subscale differed between pre-pandemic and mid-pandemic students. No differences were found in any academic and professional development skills between the pre- and mid-pandemic students, and there were significant improvements in student confidence levels for practice readiness among the mid-pandemic students. In conclusion, the pandemic appeared to affect students' stress and avoidant coping mechanism but had variable effects on academic and professional development and practice readiness.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11359405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Characterization in Patients Using Benzodiazepines While Providing Pharmaceutical Care Dispensing Service. 在提供药品护理配药服务时使用苯二氮卓类药物的患者的风险特征。
IF 2
Pharmacy Pub Date : 2024-07-31 DOI: 10.3390/pharmacy12040120
Daida Alberto Armas, Verónica Hernández García, Yanira Román Castillo, Juan Ramón Santana Ayala, Franc Capdevila Finestres, Arturo Hardisson de la Torre, Carmen Rubio Armendáriz
{"title":"Risk Characterization in Patients Using Benzodiazepines While Providing Pharmaceutical Care Dispensing Service.","authors":"Daida Alberto Armas, Verónica Hernández García, Yanira Román Castillo, Juan Ramón Santana Ayala, Franc Capdevila Finestres, Arturo Hardisson de la Torre, Carmen Rubio Armendáriz","doi":"10.3390/pharmacy12040120","DOIUrl":"10.3390/pharmacy12040120","url":null,"abstract":"<p><strong>Background: </strong>Tolerance and dependence stand out as the most relevant risks observed during benzodiazepine (BZD) treatments.</p><p><strong>Objectives: </strong>To evaluate the degree of dependence of patients on BZD treatments using the Tyrer test; to define a profile of patients at risk of developing BZD dependence; and to discuss the role of the pharmaceutical care offered by the community pharmacy during dispensing.</p><p><strong>Methods: </strong>Prospective cross-sectional descriptive observational study (August 2020-February 2021) involving 127 patients using BZD. They voluntarily answered a questionnaire during the dispensing pharmaceutical care service. The study was evaluated and codified (code: DAA-CLO-2020-01) by the Spanish Agency for Drugs and Health Products (AEMPS), and statistical analysis was performed with SPSS 25.0.</p><p><strong>Results: </strong>19.05% of patients using BZD were suspected of suffering from BZD tolerance, and 77.88% of all patients were identified as being at a high risk of BZD dependence. The Tyrer test for dependence indicated a mean score of 5.59 out of 13 points. An 18-fold increased risk of developing dependence was detected in the case of coexistence of high anxiety or depression.</p><p><strong>Conclusions: </strong>The community pharmacy, through protocolized care practices and supported by tools such as the Tyrer test, can play a decisive role in the detection, prevention, and resolution of the risks associated with BZD treatments.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11359597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacist-Led Deprescribing of Opioids and Benzodiazepines in Older Adults: Examining Implementation and Perceptions. 药剂师指导老年人开具阿片类药物和苯二氮卓类药物处方:检查实施情况和看法。
IF 2
Pharmacy Pub Date : 2024-07-30 DOI: 10.3390/pharmacy12040119
Tamera D Hughes, Elizabeth Sottung, Juliet Nowak, Kimberly A Sanders
{"title":"Pharmacist-Led Deprescribing of Opioids and Benzodiazepines in Older Adults: Examining Implementation and Perceptions.","authors":"Tamera D Hughes, Elizabeth Sottung, Juliet Nowak, Kimberly A Sanders","doi":"10.3390/pharmacy12040119","DOIUrl":"10.3390/pharmacy12040119","url":null,"abstract":"<p><p><b>Background:</b> This study examines the implementation and perceptions of a pharmacist consultant deprescribing program aimed at reducing the risk of falls in older adults using opioids and benzodiazepines. <b>Methods:</b> This qualitative study conducted interviews with healthcare providers. The interviews were conducted from August to December 2021 and analyzed using inductive coding techniques. <b>Results:</b> Five participants, predominantly female MDs or PA-Cs from rural clinics, were interviewed. The participants adopted a pharmacist-led deprescribing program due to their heightened awareness of the opioid crisis, dedication to patient safety, and a desire for opioid deprescribing education. Initially, concerns included patient resistance and provider-driven barriers. However, over time, patient attitudes shifted toward greater openness to the program. The providers emphasized several critical needs for the success of the program: guaranteed access to pharmacists, tailored patient education, resources specific to providers, and financial support, including telehealth options. These factors were deemed essential to overcoming initial barriers and ensuring effective implementation. <b>Conclusion:</b> Integrating pharmacists into primary care settings shows promise for deprescribing opioids and benzodiazepines in older adults. Future research should explore telehealth options for patient-pharmacist consultations and expand the application of these findings to other healthcare settings. The study highlights the importance of awareness, patient education, access to resources (pharmacists), and provider support in addressing deprescribing among older adults.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Justice Component of a JEDI (Justice, Equity, Diversity, and Inclusion) Inventory in a College of Pharmacy. 分析药学院 JEDI(正义、公平、多样性和包容性)清单中的正义部分。
IF 2
Pharmacy Pub Date : 2024-07-29 DOI: 10.3390/pharmacy12040118
Chad W Schulz, Jackson J Dubas, Allison M Dering-Anderson, Karen L Hoff, Adam L Roskam, Noah A Kasbohm, Brady W Holtmeier, Hannah L Hansen, Kaitlyn L Stukenholtz, Ashley N Carron, Lindsey M Tjards
{"title":"Analysis of the Justice Component of a JEDI (Justice, Equity, Diversity, and Inclusion) Inventory in a College of Pharmacy.","authors":"Chad W Schulz, Jackson J Dubas, Allison M Dering-Anderson, Karen L Hoff, Adam L Roskam, Noah A Kasbohm, Brady W Holtmeier, Hannah L Hansen, Kaitlyn L Stukenholtz, Ashley N Carron, Lindsey M Tjards","doi":"10.3390/pharmacy12040118","DOIUrl":"10.3390/pharmacy12040118","url":null,"abstract":"<p><p>At the University of Nebraska Medical Center College of Pharmacy, a longitudinal project is underway to assess how the college is functioning in terms of keeping Justice, Equity, Diversity, and Inclusion (JEDI) at the forefront of the institution. This study is intended to showcase areas of excellence within the college and as a quality improvement exercise to show the institution potential areas in need of improvement. This process was also initiated because such assessments may soon become a requirement for colleges of pharmacy to earn full accreditation. Upon analyzing the Justice component of JEDI and the 32 justice-related ideas that were recommended for exploration and discussion, and further sub-categorized under the terms representation, curriculum and education, policies and procedures, support and resources, and college climate, useful data were discovered. Overall, the information found on representation, policy and procedure, and college climate was difficult to quantify as much of the information was subjective; however, this does not automatically discount this information from being useful. Information relating to curriculum and education was more quantifiable but may be underrepresented. Analyzing information found relating to resources was made possible by identifying readily available support offered at the college for faculty, staff, and students. In identifying these resources, the college was able to take note of any missing support that needed to be implemented to ensure justice was being maintained. This longitudinal process not only allows the college to see areas where they thrive, but it also highlights any shortcomings of the college while providing the institution with information to spark innovative ideas to strengthen and further promote justice.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electronic Logistic Management Information System in Public Health Facilities and Its Implications for the Medicine Supply Chain in Singida District Council, Tanzania. 坦桑尼亚辛吉达区议会公共卫生设施电子物流管理信息系统及其对药品供应链的影响。
IF 2
Pharmacy Pub Date : 2024-07-18 DOI: 10.3390/pharmacy12040112
Anwar Milulu, Stanley Mwita, Namanya Basinda
{"title":"Electronic Logistic Management Information System in Public Health Facilities and Its Implications for the Medicine Supply Chain in Singida District Council, Tanzania.","authors":"Anwar Milulu, Stanley Mwita, Namanya Basinda","doi":"10.3390/pharmacy12040112","DOIUrl":"10.3390/pharmacy12040112","url":null,"abstract":"<p><p>The effective management of the medicine supply chain is crucial for ensuring the availability of essential medicines and supplies in public health facilities. This study aimed to determine the utilization of the electronic logistic management information system (e-LMIS) in public health facilities and its implications for the medicine supply chain. A mixed methods approach, combining both quantitative and qualitative data collection methods, was used. The study included 106 healthcare providers from 35 public health facilities in Singida District. Six key informants were interviewed using a qualitative method. Of the 106 participants, 62.3% said they were somehow competent in e-LMIS utilization. In in-depth interviews, respondents underscored the system's utility for tracking stock levels, procurements, and managing orders. Staff shortages and a lack of customized training were mentioned as major challenges hindering efficiency in managing drug supplies. This study highlighted the positive impact of e-LMIS on various aspects of the medicine supply chain, including the timely submission of orders and enhanced inventory management. Sustained management support and the regular utilization of the e-LMIS system are crucial for building and maintaining competence among healthcare providers, thereby optimizing the medicine supply chain and ultimately improving healthcare delivery.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Role of Community Pharmacists in Pain Management: Enablers and Challenges. 探索社区药剂师在疼痛管理中的作用:促进因素与挑战。
IF 2
Pharmacy Pub Date : 2024-07-18 DOI: 10.3390/pharmacy12040111
Syed Hassan Mujtaba, Parisa Gazerani
{"title":"Exploring the Role of Community Pharmacists in Pain Management: Enablers and Challenges.","authors":"Syed Hassan Mujtaba, Parisa Gazerani","doi":"10.3390/pharmacy12040111","DOIUrl":"10.3390/pharmacy12040111","url":null,"abstract":"<p><p>Pain is a common complaint, and the consumption of analgesics is prevalent. Community pharmacists, as primary contact points for patients, can play a crucial role in guiding patients toward rational pharmacotherapy or alternative pain management strategies. However, there are no specific educational curricula or standard guidelines to support this role, and the perception of this potential role is not well known. We conducted an anonymous online questionnaire among community pharmacists in Norway to assess their knowledge, perspectives, and willingness to engage in pain care. The survey also explored potential facilitators and barriers, and the use of any current guidelines. Seventy-one community pharmacists participated from various regions in Norway. Findings revealed that community pharmacists felt knowledgeable and willing to engage in pain management but anticipated barriers such as time constraints and a lack of standard guidelines. Participants also highlighted the need for better collaboration with other healthcare professionals and continuous professional development to enhance their role. To optimize the role of community pharmacists in pain management, therefore, integrating them into multidisciplinary healthcare teams, minimizing barriers, and providing continuous education and standard guidelines seem essential. This approach can empower community pharmacists and improve pain management outcomes.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Validation of a Tool to Explore Attitudes Towards meDication adHErence Using a Novel Self-Reported QuestionnairE (ADHERE-7). 使用新型自述式问卷调查表(ADHERE-7)开发并验证了一种用于探究对坚持用药的态度的工具。
IF 2
Pharmacy Pub Date : 2024-07-18 DOI: 10.3390/pharmacy12040113
Iva Bužančić, Mislav Balen, Dahna Arbanas, Slaven Falamić, Katarina Fehir Šola, Ana Galić Skoko, Mirna Momčilović, Ante Orbanić, Alena Tatarević, Maja Ortner Hadžiabdić
{"title":"Development and Validation of a Tool to Explore Attitudes Towards meDication adHErence Using a Novel Self-Reported QuestionnairE (ADHERE-7).","authors":"Iva Bužančić, Mislav Balen, Dahna Arbanas, Slaven Falamić, Katarina Fehir Šola, Ana Galić Skoko, Mirna Momčilović, Ante Orbanić, Alena Tatarević, Maja Ortner Hadžiabdić","doi":"10.3390/pharmacy12040113","DOIUrl":"10.3390/pharmacy12040113","url":null,"abstract":"<p><p>Despite the availability of various tools for measuring medication adherence, efficiently identifying non-adherence levels and reasons at the point of care remains challenging. Existing tools often lack the ease of use needed for practical clinical application. This study aimed to develop and validate a user-friendly tool to provide healthcare professionals with a concise yet comprehensive means of identifying adherence behaviors. The methodology consisted of two phases: tool items were first developed using the nominal group technique with healthcare professionals, followed by a cross-sectional pilot study involving community-dwelling adults in Croatia. Validation analysis indicated acceptable face and content validity and satisfactory criterion validity, with Attitudes towards meDication adHErence self-Reported questionnairE (ADHERE-7) scores correlating with both the self-reported five-item Medication Adherence Report Scale (MARS-5 tool) (ρ = 0.765; <i>p</i> < 0.001) and an objective measure of the proportion of days covered (PDC) from pharmacy prescription claims data (G = 0.586; <i>p</i> = 0.015). Construct validity revealed three factors: Aversion, Comfort, and Practical Non-Adherence, with Cronbach's alpha values of 0.617 for Aversion and 0.714 for Comfort Non-Adherence. The mean total score for ADHERE-7 was 26.27 ± 2.41 (range 17 to 28). This robust validation process confirms the ADHERE-7 tool as a reliable instrument for assessing medication adherence, addressing aversion, comfort, practical issues, and both intentional and unintentional nonadherence.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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