Journal of BioMedical Research and Clinical Practice最新文献_第5页

Gastrointestinal Parasitic Infestation in HIV Positive and Negative Patients Attending Clinics in a Tertiary Health Care Centre in Benue State, Nigeria. 尼日利亚贝努埃州三级保健中心门诊的艾滋病毒阳性和阴性患者的胃肠道寄生虫感染。

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-07-06 DOI: 10.46912/JBRCP.115

L. Utume, TE Ikpom, AE Obaje, E. Omudu

{"title":"Gastrointestinal Parasitic Infestation in HIV Positive and Negative Patients Attending Clinics in a Tertiary Health Care Centre in Benue State, Nigeria.","authors":"L. Utume, TE Ikpom, AE Obaje, E. Omudu","doi":"10.46912/JBRCP.115","DOIUrl":"https://doi.org/10.46912/JBRCP.115","url":null,"abstract":"Gastrointestinal parasitic infection is usually asymptomatic thus goes unnoticed and untreated for long periods of time, often resulting in other serious health complications. In HIV positive patients, the effects usually are more devastating owing to the fact that such patients are already immunocompromised. For this study, HIV positive patients were raised from the BSUTH STD/ART clinic records while HIV negative patients were recruited from other clinics by confirming their HIV status using Determine test strips to check for HIV antibodies; socio-demographic data was generated from questionnaires administered. Patients already placed on anti-helminths or anti-protozoan medicines were exempted from the study. Stool samples (n=550; 304 males 246 females) were examined for intestinal parasites using the standard parasitological procedures for direct wet mount and Formol-Ether Concentration methods. Gastrointestinal parasites were identified from 199 (36.2%) samples implying positive results for these infections: Giardia lamblia (3.8%), Entamoeba histolytica (8.9%), Ascaris lumbricoides (7.1%), Entamoeba coli (4.2%), Trichuris trichuria (3.3%), Strongyloides stercoralis (2.2%), Taenia sp. (1.8%), Trichomonas hominis (0.5%) and hookworms (2.9%). Out of this 199 only 55 (27.6%) were HIV positive; statistically there was a significant relationship between HIV status and the rate of parasitic infection (P<0.05). Personal hygiene practices, environmental sanitary conditions, overcrowding, limited access to clean potable water and poor drainage systems influenced gastrointestinal parasitic infection in both HIV positive and negative patients, HIV status may have increased intensity of gastrointestinal parasitic infection. The need for preventive awareness campaigns and mass chemoprophylaxis exercises cannot be overemphasized; government and private sector collaborations will have a wider coverage area and make a lot of impact.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125415474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Pattern of Ocular and Adnexal Injuries Requiring Surgical Intervention among Children in a Tertiary Center in North-Central Nigeria: A 14 Year Review 尼日利亚中北部三级中心儿童眼部和附件损伤需要手术干预的模式:一项14年的回顾

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-07-06 DOI: 10.46912/JBRCP.114

O. Odugbo, P. Wade, Ro Ewuga, C. Mpyet

{"title":"Pattern of Ocular and Adnexal Injuries Requiring Surgical Intervention among Children in a Tertiary Center in North-Central Nigeria: A 14 Year Review","authors":"O. Odugbo, P. Wade, Ro Ewuga, C. Mpyet","doi":"10.46912/JBRCP.114","DOIUrl":"https://doi.org/10.46912/JBRCP.114","url":null,"abstract":"The study assessed the pattern of ocular and adnexal injuries that required surgical intervention among children with the aim of strengthening preventive, curative and promotive eye care services. The ophthalmic surgical database of the facility was retrospectively reviewed to obtain information on children who had surgical intervention due to trauma from 1st January 2004-31st December 2017; these included demographic data; diagnosis, procedure and the type of anaesthesia administered. Epi Info software, version 3.4 was used for analysis. A total of 361 children (aged <18years) underwent a surgical procedure as a result of ocular trauma within the stated period. There were more males 255(70.6%) than females 106(29.4%) with a male:female ratio of 2.4:1. The mean age was 7.7±3.5years, 356(98.6%) participants had general anaesthesia administered, 267(73.9%) were aged ≤10 years. The main indications for surgical intervention were corneal laceration 143(39.6%), traumatic cataract 99(27.4%), corneo-scleral laceration 34(9.4%), lid ± canalicular laceration 21 (5.8%), intraocular foreign body 16(4.4%), ruptured globe 14(3.9%) and limbal rupture 11(3.1%). A higher proportion of males had corneal laceration 104(40.8%, p=0.40), intraocular foreign body 13(5.1%, p=0.25) and ruptured globe 12(4.7%, p=0.17) while a higher proportion of females had traumatic cataract 35(33%, p=0.14), lid laceration 4(3.8%, p=0.76) and scleral laceration 2(2.8%, p=0.33). The observed differences were however not statistically significant. Of 21 participants who had lid injuries 14(66.7%) were aged ≤5years. Of 14 participants who had ruptured globe, 8(57.1%) were aged 11-17years. We observed that a male child is twice more likely to have an ophthalmic surgery due to trauma.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125612771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Post-traumatic Stress Disorder and Functional Disability among Internally Displaced Persons in North-East Nigeria 尼日利亚东北部境内流离失所者中的创伤后应激障碍和功能残疾

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-07-06 DOI: 10.46912/jbrcp.105

C. Nwoga, S. Dakwak, M. Audu, S. Goar, T. Agbir, A. Armiya’u, Y. Maigari, N. O. Obayi, C. Eze

{"title":"Post-traumatic Stress Disorder and Functional Disability among Internally Displaced Persons in North-East Nigeria","authors":"C. Nwoga, S. Dakwak, M. Audu, S. Goar, T. Agbir, A. Armiya’u, Y. Maigari, N. O. Obayi, C. Eze","doi":"10.46912/jbrcp.105","DOIUrl":"https://doi.org/10.46912/jbrcp.105","url":null,"abstract":"The prolonged Boko Haram crises in North-East Nigeria caused serious displacement and left the survivors with multiple psychological consequences such as Posttraumatic stress disorder (PTSD). A high prevalence rate of PTSD among Internally Displaced Persons (IDPs) has been reported across literatures. This study aimed to determine the factors that are associated with PTSD and its relationship with functional disability among IDPs in Yobe State, Nigeria. This was a cross sectional study of 450 respondents, recruited using a systematic sampling method. We used Harvard Trauma Questionnaire to screen for symptoms of PTSD and definite diagnosis made with WHO Composite International Diagnostic Interview (CIDI), PTSD Module. Hopkins Symptom Checklist was used for symptoms of depression and definite diagnosis made with CIDI Depression Module. The WHO Disability Assessment Schedule 2.0 was used to measure functional disability. There were 192 (45.5%) males and 230(54.5%) female respondents. The mean age of respondents was 39.4±18.50 years with range of 18-80 years. Significant PTSD symptoms were found among 159(37.7%) of the IDPs while Clinical interview gave a definite prevalence of 18.5%. Two hundred and forty-four (57.8%) of the respondents had disability scores in the mild range, 17.5% in the moderate range while 20.7% were in the severe range. Majority of those with disability scores in the severe range had PTSD. Factors significantly associated with PTSD were age, marital status, duration of displacement, type of abode, general living condition, self-reported general health, and disability score. A High prevalence rate of PTSD was found among IDPs and the severity of disability correlated well with having diagnosis of PTSD in the study.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132353813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectrum of Skin Diseases among School Aged Children in Jos North-Central Nigeria 尼日利亚中北部乔斯学龄儿童皮肤病谱

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-07-06 DOI: 10.46912/jbrcp.v2.i2.2019.108

R. Adah, G. Adah, H. Abdu, C. John, S. Okolo

{"title":"Spectrum of Skin Diseases among School Aged Children in Jos North-Central Nigeria","authors":"R. Adah, G. Adah, H. Abdu, C. John, S. Okolo","doi":"10.46912/jbrcp.v2.i2.2019.108","DOIUrl":"https://doi.org/10.46912/jbrcp.v2.i2.2019.108","url":null,"abstract":"Skin diseases are common causes of morbidity among children in developing Nations. An awareness of the types of skin morbidities seen in school children and the associated factors may enable individuals’ families and government carry out or direct preventive and therapeutic measures appropriately. The aim of this study was to assess the spectrum of skin diseases among primary school children in Jos North Local Government Area. Three hundred and ninety (390) pupils were recruited from some public and private primary schools using multistage sampling technique. Structured Interviewer-administered questionnaires were used to obtain information. Key diagnostics features were used for clinical diagnosis of major skin diseases. Data collected were analyzed using SPSS version 21. There were a total of 199 males and 191 females. Age range was between 6 and 12 years. Prevalence rate of skin disease was 36.2%. A total of 28 different types of skin diseases were seen among the pupils, with infections making up the bulk (47.3%). Among the infections, Tinea (23.9%) was the most prevalent. while dermatitis accounted for 20.7%. There was no sex predilection. Skin diseases were significantly more prevalent in children between 6-7 years ( p-0.014) and associated with lower socioeconomic class (p-0.001) and children from public schools (p-0.000). Preventive and curative health services should be provided in the school health programme especially in public schools for reduction of the prevalence of skin disorders.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129595911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Correlates of HIV Risky Sexual Behaviours in an Era of Antiretroviral Therapy Scale‐Up: A Cross-Sectional Study among the Adult General Population in Nasarawa State, Nigeria 抗逆转录病毒治疗时代HIV高危性行为的相关因素:尼日利亚纳萨拉瓦州成年普通人群的横断面研究

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-04-04 DOI: 10.46912/JBRCP.101

I. Bako, J. Anyanti, A. Roca-Feltrer

{"title":"Correlates of HIV Risky Sexual Behaviours in an Era of Antiretroviral Therapy Scale‐Up: A Cross-Sectional Study among the Adult General Population in Nasarawa State, Nigeria","authors":"I. Bako, J. Anyanti, A. Roca-Feltrer","doi":"10.46912/JBRCP.101","DOIUrl":"https://doi.org/10.46912/JBRCP.101","url":null,"abstract":"Analyses of HIV incidence in Nasarawa State Nigeria estimate that most of the new HIV infections occur among persons who reported low HIV risk including couples. The study was aimed at identifying the factors that predict risky sexual behavior among the general population in Nasarawa state, Nigeria. Data analysis was carried on a total of 801 respondents sampled from the general population of Nasarawa State, Nigeria. The original sample was obtained through a two-stage cluster sampling technique using probability proportionate to size. The primary outcome variable was risky sexual behavior. Chi-square and logistic regression analyses were used to determine the association between the outcome and selected Sociodemographic and other independent variables. Females were 54.2% of the total sampled population analysed, the mean age of the respondents was 29.8 years (SD: 10.3). About two-third of the respondents engaged in risky sexual behaviours (65.9%) but only 4.7% considered themselves to be at high risk of HIV. The multivariable regression analysis showed that factors associated with risky sexual behaviour included : been male sex [OR: 0.63; 95% CI: 0.436-0.915], married [OR: 0.26: 95% CI: 0.163 - 0.419], rural resident [OR: 1.20; 95% CI: 0.775 to 1.871 ], age 20-24 [OR: 1.93, 95% CI: 1.113 - 3.360] and 25-29 years [OR: 2.34; 95% CI: 1.267-1.308]; and knowledge of HIV [OR: 1.49; 95% CI: 1.056-2.108].There is a need to urgently intensify media campaigns, community-based interventions including one on one communications to reduce risky sexual behaviours.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115615130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Detection of Hepatitis C Virus amongst Patients in Five Selected Hospitals in Niger State, Nigeria 尼日利亚尼日尔州5家选定医院患者中丙型肝炎病毒的分子检测

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-04-04 DOI: 10.46912/JBRCP.V2.I1.2019.100

MU Iduh, FA Kuta, ME Abalaka

引用次数: 0

Evaluation of Wound Healing Potential of Chrysophyllum albidum Hexane Seed Extract in Wistar Rat 菊花己烷种子提取物对Wistar大鼠创面愈合潜力的评价

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-04-04 DOI: 10.46912/JBRCP.110

R D Oladeji, O. Babatunde, I A Ajayi

{"title":"Evaluation of Wound Healing Potential of Chrysophyllum albidum Hexane Seed Extract in Wistar Rat","authors":"R D Oladeji, O. Babatunde, I A Ajayi","doi":"10.46912/JBRCP.110","DOIUrl":"https://doi.org/10.46912/JBRCP.110","url":null,"abstract":"Phytochemical, antioxidant and antimicrobial activities of the seeds of Chrysophyllum albidum have been established. However, scientific evaluation of its wound healing activity is lacking. Thus, this study was aimed at evaluating the wound healing potential of Chrysophyllum albidum hexane seed extract using wistar rats. The seed cotyledon was collected, air-dried, blended and extracted with n-hexane by continuous cold extraction. Phytochemicals, antioxidant and antimicrobial activities of the extracts were assayed by standard methods. Three groups of male wistar rats consisting of seven animals each were used for the animal studies. Wound excision was induced on all animals in the sterilized shaved dorsal fur region.Group1 served as the negative control (untreated), groups 2 and 3 were treated with n-hexane extract (test group) and Povidone-iodine ointment (positive control) respectively. Wound contraction rate and epithelialization time were used to assess the efficiency of the treatment. Group 3 rats had best wound contraction rate with epithelialization time of 16 post-wounding day followed by group 2 (20 days) and group 1 (28 days). The wound healing efficiency of the extract was less than that of the standard ointment but it healed the wound inflicted on the rats faster than the untreated ones. The low wound activity of the seed extract may be due to low phytochemical, antioxidant and antimicrobial activity of the extract. Chrysophyllum albidum hexane seed extract have some wound healing activity and therefore have potential for being used as wound healing ointment.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128285165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Role of Histopathological Analysis in Diagnosing Steroid Cell Tumour: A Case Report 组织病理学分析在类固醇细胞瘤诊断中的作用:1例报告

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-04-04 DOI: 10.46912/JBRCP.V2.I1.2019.102

S. Ohayi

引用次数: 0

Cause and Effect Relationship of Body Weight and Knee Osteoarthritis: Experience from a Tertiary Institution in South-Eastern Nigeria 体重与膝关节骨关节炎的因果关系:来自尼日利亚东南部一所高等教育机构的经验

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-04-04 DOI: 10.46912/JBRCP.93

C. G. Oguzie, O. Lasebikan, C. Onyempka, D. Chukwumam, V. Asodike, C. Mbalewe, C. Ihezie, S. Emdin

{"title":"Cause and Effect Relationship of Body Weight and Knee Osteoarthritis: Experience from a Tertiary Institution in South-Eastern Nigeria","authors":"C. G. Oguzie, O. Lasebikan, C. Onyempka, D. Chukwumam, V. Asodike, C. Mbalewe, C. Ihezie, S. Emdin","doi":"10.46912/JBRCP.93","DOIUrl":"https://doi.org/10.46912/JBRCP.93","url":null,"abstract":"It is well established that obesity is related to osteoarthritis of the knees. The aim of this study was to investigate the risk of knee osteoarthritis in relation to body mass index (BMI) and specifically, to assess the risk of knee osteoarthritis (OA) attributable to obesity. We also aimed to determine if there is a higher risk with an increase in BMI. This is an observational case-referent study of patients with knee pain. Patients were recruited from the orthopaedics clinic. The cases were patients that presented with radiologically diagnosed knee osteoarthritis, while the referents were other patients that also attended the orthopedic clinic at the same time. The referents were randomly selected. Body Mass Index was calculated and classified based on the WHO international classification. Data were analyzed using SPSS version 21. A total of 152 patients were included in the study and 67.1% were females while 32.9% were males giving a ratio of 2:1. The mean age was 57.72+/-12.5 years, the mean weight was 79.47+/- 13.41kg (95% CI 77.32 – 81.62) and the mean BMI was 27.80+/-6.2kg/m2. 56.6% had knee osteoarthritis. 8.6% (n = 13) were bilateral, 18.4% (n = 28) in the left knee and 29.6% (n = 45) in the right knee. The relationship between obesity and the presence of knee osteoarthritis was statistically significant (p 0.047). A Chi-squared test for trend also did not show an increased risk for knee osteoarthritis with increasing BMI (p 0.105). In conclusion, knee osteoarthritis is a degenerative joint disease that mostly affects the elderly. Our findings give strong support to the already existing knowledge of the positive relationship between obesity and knee osteoarthritis; however, increasing BMI did not increase the risk of knee OA.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128944000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship between Intimate Partner Violence and Postpartum Depression in a North-Central State of Nigeria 尼日利亚中北部州亲密伴侣暴力与产后抑郁症的关系

Journal of BioMedical Research and Clinical Practice Pub Date : 2019-04-04 DOI: 10.46912/jbrcp.95

I. Tor-anyiin, T. Igbudu, S. Tor-Agbidye

{"title":"The Relationship between Intimate Partner Violence and Postpartum Depression in a North-Central State of Nigeria","authors":"I. Tor-anyiin, T. Igbudu, S. Tor-Agbidye","doi":"10.46912/jbrcp.95","DOIUrl":"https://doi.org/10.46912/jbrcp.95","url":null,"abstract":"Postpartum depression affects 10-15% of women in the immediate post delivery period. It has adverse effects on the family and her members. There are trigger factors that contribute to the development of depression among mothers. These factors; when identified and addressed, present an opportunity in reducing the prevalence of postpartum depression and its adverse effects on the family. Hence, the objective of the study was to study the relationship between Intimate Partner Violence (IPV) and Postpartum Depression (PPD) among women in Federal Medical Centre Makurdi. This was a cross-sectional study of mothers who presented with their children at the immunization clinic. Three hundred and thirty postpartum women were selected by a systematic random sampling technique. PPD and IPV were assessed using the Edinburgh Postpartum Depression Scale and the HITS (Hit, Insult, Threaten and Scream) scale respectively. The results showed that the mean age of participants was 28±5years. The prevalence of PPD was 27.6% while that of IPV was 22.4%. A statistically significant relationship was demonstrated between IPV and PPD (χ2 = 143.15, p < 0.0001). The prevalence of PPD and IPV were high, affecting approximately a quarter of postpartum women in Makurdi. IPV contributes to the development of PPD (OR=35.35, CI=17.39-71.87). Hence the need for screening of these conditions by physicians. Appropriate prevention modalities against IPV could curb postpartum depression and its effects on the family.","PeriodicalId":301476,"journal":{"name":"Journal of BioMedical Research and Clinical Practice","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121449183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0