Dental Materials最新文献

{"title":"Improvement of the biological performance of filling materials for primary teeth after pulpectomy by incorporating Ca-polyP microparticles.","authors":"Yun Ouyang, Jinwen Wang, Jiali Ma, Jian Yu, Huan Zhou, Lei Yang, Guohua Yuan","doi":"10.1016/j.dental.2026.06.016","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.016","url":null,"abstract":"<p><strong>Objectives: </strong>Calcium Hydroxide/Iodoform pastes (CH-I) are used for pulpectomy in primary teeth. To alleviate the rapid degradation of CH-I, polyphosphate (poly P) was incorporated with CH to form a modified paste (CH-PP-I), which was evaluated against CH-I and a commercial paste (Vitapex®).</p><p><strong>Methods: </strong>Vitapex, CH-I and CH-PP-I were compared for injectability, viscosity, pH, Ca^2 + release and solubility. Antimicrobial properties of the pastes were tested using Enterococcus faecalis (E. faecalis). Their effects on human periodontal ligament cells (hPDLCs) were explored using CCK-8, Edu and TUNEL assays. Their impact on osteogenic and osteoclastic differentiation was detected on dental follicle stem cells (DFSCs) and bone marrow mononuclear cells (BMMs). The test materials were implanted subcutaneously to assess in vivo biocompatibility and degradation rates.</p><p><strong>Results: </strong>CH-PP-I released calcium more slowly and consistently than CH-I. CH-PP-I showed superior bacteriostatic properties than Vitapex, similar to CH-I. CH-PP-I exhibited lower cytotoxicity on hPDLCs compared to Vitapex and CH-I, with cell proliferation and apoptosis barely affected. CH-PP-I also promoted osteogenic differentiation of DFSCs and inhibited osteoclast differentiation of BMMs. Subcutaneous implantation revealed moderate inflammation in CH-PP-I and CH-I groups, while severe inflammation in the Vitapex group on day 15. After 60 days, all groups showed mild to moderate inflammation, and CH-PP-I had the lowest degradation rate on day 90.</p><p><strong>Significance: </strong>CH-PP-I exhibited more excellent antimicrobial activity and a lower degradation rate than CH-I and Vitapex, highlighting its potential as a promising filling paste for primary teeth.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of simulated gastric acid ageing on Martens hardness of denture base resins fabricated using different techniques.","authors":"Abdulaziz Alhotan, Ahmed Altarazi, Shaymaa Mudhaffer, Hanan Al-Johani, Nick Silikas","doi":"10.1016/j.dental.2026.06.020","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.020","url":null,"abstract":"<p><strong>Objectives: </strong>Gastro-oesophageal reflux disease exposes denture base resins to acidic conditions that may compromise their mechanical properties. This study assessed the effect of simulated gastric acid ageing on the Martens parameters of heat-polymerised, CAD/CAM milled, and 3D-printed polymethyl methacrylate (PMMA).</p><p><strong>Methods: </strong>Three denture base resins were investigated: heat-polymerised (Lucitone 199), CAD/CAM milled (G-CAM), and 3D-printed (Denturetec). Specimens (n = 5 per group) were aged in artificial saliva (pH 5.5) or simulated gastric acid (pH 1.2) at 37°C for 24 and 96 h, corresponding to approximately 2.5 and 10 years of clinical exposure. Martens indentation testing was performed, and the following parameters were measured; Martens hardness (H_M), indentation depth (I_D), indentation modulus (E_IT), and creep indentation (C_IT). Data were analysed using two-way ANOVA and Tukey post hoc tests (α = 0.05).</p><p><strong>Results: </strong>Resin type significantly affected all Martens parameters (p < 0.001), with milled resin exhibiting the highest H_M and E_IT values and 3D-printed resin showing the highest I_D values. Ageing solvent significantly impacted H_M, I_D, and E_IT (p ≤ 0.049). Gastric acid exposure caused significant deterioration in Martens parameters, particularly at 96 h. Heat-polymerised and milled PMMA exhibited significant differences between solvents at specific time points, whereas 3D-printed resins remained largely unaffected by the ageing solvent.</p><p><strong>Significance: </strong>These findings suggest that material selection based on fabrication technique may influence denture longevity in patients with chronic acid exposure, such as those with gastro-oesophageal reflux disease or eating disorders. The immersion-to-clinical time equivalence represents an approximation based on previously published accelerated ageing models and should be interpreted as a standardised testing protocol rather than an exact clinical simulation.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and performance evaluation of biphenyl-based high-performance dental composite resins reinforced with porous lithium disilicate.","authors":"Yongcheng Ge, Ting Zhao, Dandan Liu, Sizheng Fan, Pengyuan Liu, Wei Li, Chengji Zhao, Xiaoqiu Liu","doi":"10.1016/j.dental.2026.06.015","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.015","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to design and investigate the mechanical, aesthetic, tribological, and biocompatibility performance of a tetramethyl-biphenyl dimethacrylate (TMBP-EMA)-based dental composite resin reinforced with porous lithium disilicate (Li₂Si₂O₅) microcrystalline particles.</p><p><strong>Materials and methods: </strong>Porous Li₂Si₂O₅ fillers were obtained by hydrofluoric acid (HF) etching and subsequently characterized. The TMBP-EMA resin matrix was synthesized and analyzed. The structure, mechanical behavior, optical properties, and polymerization performance of the Li₂Si₂O₅/TMBP-EMA composite resins were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and other methods, with mechanical properties evaluated in terms of flexural modulus, flexural strength, and Vickers hardness.</p><p><strong>Results: </strong>Porous Li₂Si₂O₅ fillers were successfully fabricated, and their porosity increased with prolonged HF etching. The Li₂Si₂O₅/TMBP-EMA composite resins showed improved degree of conversion, reduced polymerization shrinkage, favorable wettability and solubility, enhanced optical properties, and improved friction behavior. Mechanical properties improved continuously with increasing porosity, with the 120-s group achieving the best results. Both SEM and finite element analysis confirmed that the porous structure enhanced interfacial bonding and optimized stress distribution, thereby improving overall properties.</p><p><strong>Significance: </strong>Incorporation of porous Li₂Si₂O₅ improved the mechanical, optical, and tribological properties of the composite resin, while improving interfacial bonding and stress distribution. Its comprehensive performance surpassed that of conventional fillers, indicating promising potential for clinical translation.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive flavonoid primers for stable and antibacterial bonding to caries-affected dentin.","authors":"Beatriz Ometto Sahadi, Carolina Bosso André, Jorge Soto-Montero, Felipe Fabrício Farias da Silva, Victor Pinheiro Feitosa, Marco Cícero Bottino, Marcelo Giannini","doi":"10.1016/j.dental.2026.06.012","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.012","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the effects of experimental primers containing baicalein (BA), kaempferol (KA), or naringin (NA) when applied to caries-affected dentin (CAD) on the adhesion, collagen stability, and antibacterial potential.</p><p><strong>Materials and methods: </strong>Extracted human molars with artificially created CAD were treated with experimental primers (20 mM BA, KA, or NA) or 3 controls: commercial adhesive only (CONT), 20% ethanol (SOL), or 0.2% chlorhexidine (CHX). Dentin bond strength (μTBS) was evaluated by microtensile test after 24 h, 12 months, and 24 months of aging. Collagen crosslinking was analyzed by micro-Raman spectroscopy, and mechanical properties of hybrid layer were assessed by nanohardness and Young's modulus at 24 h and 12 months. Antibacterial activity was evaluated using a microcosm biofilm model through colony-forming unit (CFU), confocal microscopy (live/dead), and biofilm morphology under SEM after 24 h of incubation. Data were analyzed by generalized linear models, ANOVA followed by Tukey's or Sidak's multiple comparison tests (α=0.05).</p><p><strong>Results: </strong>Flavonoid primers significantly affected both bonding performance and bacterial viability (p < 0.05). After 24 months, BA and NA maintained μTBS values comparable to baseline and significantly higher than the CONT and CHX. Raman spectra revealed exclusive collagen crosslinking vibration with BA treatment. Nanohardness and modulus showed no changes over time. BA and NA exhibited strong antibacterial effects, reducing S. mutans and total lactobacilli counts and disrupting biofilm structure, with cell death proportions comparable to CHX.</p><p><strong>Conclusion: </strong>Flavonoid-based primers, particularly those containing baicalein and naringin, demonstrated dual chemical-biological mechanism in CAD that enhanced the dentin bonding longevity with sustained antibacterial activity. They are multifunctional agents for minimally invasive and durable restorative strategies.</p><p><strong>Clinical significance: </strong>Restoring cavities with caries-affected dentin is a challenge for restorative dentistry, which can be minimized by applying flavonoid-based primers that prevent early degradation of dentin adhesion and act as an antibacterial agent in contaminated tissue.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatigue behaviour of direct and CAD/CAM indirect restorative materials bonded to a dentine analogue substrate.","authors":"Yanning Chen, Ding Hao, Qianhui Li, Shujiang Chen, Xuedong Bai, Edmond Ho Nang Pow, James Kit Hon Tsoi","doi":"10.1016/j.dental.2026.06.013","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.013","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the fatigue behaviour of direct and CAD/CAM indirect restorative materials cemented to a dentine analogue substrate.</p><p><strong>Materials & methods: </strong>Two resin-based direct restorative materials (G-ænial Universal Injectable, GU; Filtek Supreme Flowable Restorative, FS), and two CAD/CAM indirect restorative materials (IPS e.max CAD, EM; Tetric CAD, TE), were tested. Flexural properties (flexural strength and flexural modulus) and energy dissipation parameters (modulus of toughness, elastic recovery, and their difference) were determined via the three-point bending (3PB) test (n = 10). After the monotonic pilot trial, the wet cyclic fatigue test was performed following the staircase approach (initial load: approx. 40% of the monotonic load; step size: approx. 5% of the monotonic load; 500,000 cycles per specimen; 20 Hz; n = 15). Mean fatigue failure load (FFL), standard deviation (SD), and 95% confidence interval (CI) were calculated using the Dixon and Mood method. FFLs were also evaluated with Weibull statistics. Specimen survival or failure was examined visually and under a stereomicroscope, then fractographic analysis were conducted on sectioned specimens under the SEM. Finite Element Analysis (FEA) was performed using the mean FFLs and 300 N axial load on tri-layer models, respectively. SPSS 26.0 was used for statistical analysis and the significant level was pre-set as α = 0.05.</p><p><strong>Results: </strong>EM showed significantly higher flexural strength and elastic modulus than the three resin-based composites (RBCs) (p < 0.001). Nevertheless, three energy dissipation parameters of RBCs were significantly higher than those of lithium disilicate, ranking TE > FS > GU > EM. The mean FFL showed a similar trend, ranking TE (353.93 ± 43.01 N) > GU (276.79 ± 34.24 N) > FS (255.33 ± 47.30 N) > EM (184.00 ± 76.92 N). EM presented the lowest Weibull parameters and the highest RSD values, while TE presented superior fatigue resistance and structural reliability. Distinct failure characteristics and stress distribution patterns between EM and three resin-matrix materials were found.</p><p><strong>Significance: </strong>Distinct fatigue behaviours were discovered between lithium disilicate and resin-based materials, including the fatigue failure load, failure mode, and stress distribution pattern. Resin-based composites outperformed lithium disilicate in the cyclic fatigue test, among which the CAD/CAM indirect RBC material performed the best fatigue resistance. Energy dissipation parameters may serve as preliminary predictors to the fatigue properties.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing printing accuracy and mechanical properties of DLP dental resin via silanized cellulose nanocrystals.","authors":"Yifan Ma, Zhihao Zhang, Di Chen, Gan Jin, Dewey Duhyeong Lee, Jong-Eun Kim","doi":"10.1016/j.dental.2026.06.011","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.011","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to synthesize silanized cellulose nanocrystals (Si-CNCs) and evaluate their efficacy as reinforcing nanofillers for enhancing the printing accuracy, mechanical properties, and surface quality of dental restorations fabricated via DLP.</p><p><strong>Methods: </strong>Si-CNCs were synthesized by grafting 3-methacryloxypropyltrimethoxysilane onto CNC surfaces and characterized using DLS, Zeta potential analysis, XPS, XRD, FTIR, TGA, and AFM. Nanocomposite resins were formulated by incorporating CNCs or Si-CNCs (0.1-2 wt%) into a UA matrix. Photopolymerization characteristics were analyzed using UV-Vis transmittance and Jacob's working curve. Printing accuracy was quantified by RMS deviation analysis of 3D-printed crowns and bridges. Mechanical properties, surface roughness, and biocompatibility were also evaluated. The significance level was set at p < 0.05.</p><p><strong>Results: </strong>Characterization confirmed successful silanization. AFM images confirmed that silanization converted CNCs from bundled agglomerates into a homogeneous dispersion. UV-Vis transmittance and Jacob's working curve revealed a concentration-dependent crossover in light extinction between the two series. The Si-CNC system retained dispersion across the full concentration range and stabilized the curing depth. Printing accuracy improved significantly over the UA control and unmodified CNCs (p < 0.05). The 0.5 wt% Si-CNC group achieved the lowest RMS for both the crown (35.48 ± 1.32 µm) and bridge (57.25 ± 4.49 µm) models, with optimal DC, Vickers hardness (25.83 ± 0.69 HV), and tensile strength (47.93 ± 4.77 MPa). Si-CNCs also produced superior surface smoothness and good cell viability.</p><p><strong>Significance: </strong>Si-CNCs reconcile high printing accuracy with robust mechanical performance in DLP dental resins. This system offers a viable strategy for high-precision dental restorations.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A high-filler-content 3D-printable composite enabled by a novel silanization process bridging the performance gap with milled materials for definitive dental prostheses.","authors":"Christelle Sanchez, Renaud Noharet, Raphael Herman, Alain Vanheusden, Amélie Mainjot","doi":"10.1016/j.dental.2026.06.014","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.014","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the mechanical and fatigue properties of an experimental high-filler-content 3D-printable dental composite incorporating a novel silanization process (Magnus), designed to increase filler content without increasing viscosity and to enhance the filler-resin interface, in comparison with commercial printed and milled composite materials.</p><p><strong>Methods: </strong>Magnus specimens were fabricated by MSLA (Phrozen). They were compared with 3D-printed OnX Tough2 (Sprintray) and milled Grandio CAD-CAM composite blocks (Voco) produced following manufacturer's recommendations. Bar specimens underwent three-point flexural testing (n = 30/material) and cyclic flexural fatigue at 150 MPa (1 Hz; n = 20/material). All tests were conducted in a 36°C water bath. Vickers microhardness, filler content, resin viscosity and degree of conversion were assessed.</p><p><strong>Results: </strong>Magnus exhibited the highest filler content reported (∼70 wt%, 53 vol%), approximately twice that of OnX Tough2 (∼35 wt%, ∼22 vol%), while maintaining lower shear viscosity. At 150 MPa, Magnus demonstrated flexural fatigue resistance 4.1-fold higher than Grandio blocs and approximately 2,100-fold higher than OnX Tough2. Flexural strength was equivalent to Grandio blocs (209.7 vs 219.3 MPa), with similar Weibull modulus. Flexural modulus was 3.2-fold higher than OnX Tough2 (7.4 vs 2.3 GPa). Fracture energy and microhardness were markedly higher than OnX Tough2. Degree of conversion exceeded 95%.</p><p><strong>Significance: </strong>Under clinically relevant wet testing conditions, this very high-filler-content 3D-printable composite maintained low viscosity while achieving markedly superior fatigue resistance compared with the tested printed and milled materials and flexural strength comparable to the milled reference, thereby bridging the mechanical performance gap between printed and milled restorative materials.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"self-assembled pH-responsive antibacterial nanoparticles disturb cell envelope integrity and suppress virulence factors of Streptococcus mutans.","authors":"Jingou Liang, Bina Yang, Jingwei Cao, Shiyong Zhang, Jing Zou, Lei Cheng","doi":"10.1016/j.dental.2026.06.010","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.010","url":null,"abstract":"<p><strong>Objective: </strong>pH-responsive materials that could target cariogenic environment have demonstrated great potential to inhibit dental caries. The objective is to investigate the anti-caries property of the self-assembled, pH-responsive antibacterial dodecylmethylaminoethyl methacrylate nanoparticles (DMAEM NPs) and explore the antibacterial mechanism.</p><p><strong>Methods: </strong>DMAEM was analyzed by computational simulation. Then it was synthesized and characterized. The in-vitro cytotoxicity and pH-responsive effect were tested in various pH values. Then, the effect of DMAEM NPs on the S. mutans biofilms was investigated with a treatment mode like daily oral care (10 min, twice per day). The RNA-seq and transcriptome analysis was conducted. The biocompatibility and anti-caries effect were also investigated in a rat model.</p><p><strong>Results: </strong>. DMAEM self-assembled into nanoparticles and the morphologies varied in different pHs. The NPs demonstrated good in-vitro biosafety and acid-activated inhibiting effect on S.mutans biofilms. With repeated short-time treatment by DMAEM NPs， the biofilm activity, lactic acid production and EPS formation were inhibited. SEM and TEM images showed the bacterial cell envelops were ruptured. On the transcriptomic level, DMAEM NPs down regulated the gene expression such as gtfBC, gbpC and lrgAB. The COG, GO and KEGG analysis showed the function of ribosome and macromolecule metabolism were mainly down regulated. In the rat model, DMAEM NPs showed no side effect on oral mucosa and reduced the caries scoring.</p><p><strong>Significance: </strong>The self-assembled, pH-responsive DMAEM NPs could inhibit the cariogenic biofilm formation and the development of dental caries. This provides an interesting strategy to combat dental caries, which is promising for future application.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148314991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatigue lifetime and microbial inhibition at the implant-abutment interface of 5Y-PSZ zirconia abutments coated with experimental glass.","authors":"Ana Carolina da Silva, Larissa Márcia Martins Alves, Ernesto Byron Benalcázar Jalkh, Juliana Campos Junqueira, Tiago Moreira Bastos Campos, Marco Antonio Bottino, Jason Alan Griggs, Estevam Augusto Bonfante, Renata Marques de Melo Marinho","doi":"10.1016/j.dental.2026.06.009","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.009","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate microbial inhibition at the implant-abutment interface of 5Y-PSZ zirconia abutments coated with boron-doped soda-lime glass, with or without silver, and to evaluate the fatigue lifetime of boron-doped soda-lime glass-coated abutments compared to uncoated control.</p><p><strong>Methods: </strong>Forty-five maxillary central incisor crowns and custom CAD/CAM 5Y-PSZ zirconia abutments were divided into three groups: Control, boron-doped soda-lime glass (BSL), and boron-doped soda-lime glass with silver (BSLAg). Microbial leakage at the implant-abutment interface was quantified by colony-forming unit (CFU) counts for Candida albicans, Streptococcus sanguinis, and Escherichia coli. Step-stress accelerated life testing (SSALT) was performed at 2 Hz with a stress ratio of 0.1 using a custom all-electric fatigue load frame. Survival probability and Weibull parameters were estimated with ALTA PRO software. Scanning electron microscopy (SEM) and fractographic analyses were conducted. CFU results were analyzed by one-way ANOVA (α = 0.05).</p><p><strong>Results: </strong>The BSL group significantly reduced microbial leakage for all tested specimens (p < 0.05), whereas the BSLAg group showed no antimicrobial effect. Consequently, only the Control and BSL groups underwent fatigue testing. No significant difference could be detected between the groups after the fatigue lifetime analysis. SEM micrographs of the BSL group revealed reduced microbial adhesion. Fractures predominantly originated from bending of the titanium interfaces (Ti base) across all groups. Significance Boron-doped soda-lime glass coating on 5Y-PSZ zirconia abutments provides a dual benefit of antimicrobial protection and preserved fatigue lifetime. This approach may help hinder the development of peri-implantitis disease by reducing microbial leakage at the implant-abutment interface without compromising mechanical reliability.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148292731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro evaluation of physical properties and bacterial adhesion of different self-adhesive flowable composite resins.","authors":"Çağla Yeloğlu-Akbuar, Ayça Sarıalioğlu Güngör, İsmail Öztürk, Evrim Dalkılıç","doi":"10.1016/j.dental.2026.06.008","DOIUrl":"https://doi.org/10.1016/j.dental.2026.06.008","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The aim of this in vitro study was to comparatively evaluate the mechanical, optical, and biological properties of different self-adhesive flowable composite resins in comparison with a conventional flowable composite resin, with particular emphasis on the potential influence between material composition and bacterial adhesion.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;Five flowable composite resins were investigated: Vertise Flow (VF), Fusio Liquid Dentin (FL), Constic (Co), Nova Compo SF (NC), and a conventional flowable composite, Filtek Ultimate Flowable (FU) (n = 10). Surface microhardness (VHN), surface roughness (Ra), and color changes after 24 h (ΔE₁) and 7 days (ΔE₂) of immersion in coffee solution were evaluated. Bacterial adhesion and growth inhibition of Streptococcus mutans and Lactobacillus casei were assessed using a crystal violet assay, supported by scanning electron microscopy (SEM). Data were analyzed using one-way ANOVA and Tukey's post hoc test (α = 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The conventional flowable composite (FU) exhibited the highest microhardness values (p &lt; 0.05). Surface roughness differed significantly among the self-adhesive materials, with FL presenting the highest Ra values (p &lt; 0.05). Color stability varied depending on material composition, with NC demonstrating the lowest ΔE values after prolonged staining (p &lt; 0.05). Bacterial adhesion was material-dependent; FU and NC showed the lowest adhesion for both bacterial species, whereas FL exhibited the highest bacterial affinity (p &lt; 0.05). Bacterial adhesion patterns could not be explained by surface roughness alone.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Self-adhesive flowable composite resins exhibited distinct mechanical, optical, and microbiological behaviors compared to a conventional flowable composite. The findings suggest that resin matrix chemistry and filler composition may influence bacterial adhesion beyond surface roughness, providing material-science-oriented insights relevant to the development and clinical selection of restorative materials. From a clinical perspective, materials with higher microhardness may be preferred for stress-bearing posterior restorations, whereas materials with lower bacterial adhesion may be advantageous for patients with high caries risk. In addition, color stability should be considered when selecting materials for anterior restorations where esthetic outcomes are critical.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;The results of this study provide clinically relevant information for the selection of flowable composite resins by demonstrating differences in mechanical properties, color stability, and bacterial adhesion. While conventional flowable composites showed superior microhardness, certain self-adhesive composites exhibited comparable surface roughness, favorable color stability, and reduced bacterial adhesion, which may contribute to favorable esthetic performance ","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148275469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}