{"title":"Long-term exposure to air pollution and incidence risk of various arrhythmias: A prospective cohort study","authors":"","doi":"10.1016/j.eehl.2024.05.006","DOIUrl":"10.1016/j.eehl.2024.05.006","url":null,"abstract":"<div><div>To investigate the association of long-term exposure to air pollution with incident arrhythmia from various causes, this prospective cohort study included 442,386 participants from the UK Biobank cohort. Residential annual average exposures at baseline were evaluated, including fine particles (PM<sub>2.5</sub>), coarse particles (PM<sub>2.5–10</sub>), nitrogen dioxide (NO<sub>2</sub>), and nitrogen oxides (NO<sub>x</sub>). We further constructed a composite air pollution score (APS) to evaluate the concomitant exposure to these four pollutants. The associations of air pollutants with various arrhythmia subtypes were assessed utilizing the Cox proportional hazards model, and the hazard ratios (HRs) for incident arrhythmias were estimated. A total of 41,021 patients with incident arrhythmia were recorded. The HRs of overall arrhythmia associated with a 10 μg/m<sup>3</sup> increment in PM<sub>2.5</sub>, PM<sub>2.5–10</sub>, NO<sub>2</sub>, and NO<sub>x</sub> were 1.26, 0.95, 1.03, and 1.02, respectively. The HR was 1.08 in the highest quintile of the APS compared to the lowest one. For cause-specific arrhythmias, the HRs per unit increment in APS were 1.45, 1.67, 1.51, 1.80, 2.63, and 4.66 for atrial fibrillation, atrioventricular block, ventricular fibrillation/tachycardia, intraventricular block, supraventricular tachycardia, and ventricular premature beats, respectively. Females, older individuals, overweight or obese individuals, and those with low education attainment, low income, or cardiometabolic morbidities had higher HRs associated with pollutants. Long-term exposure to air pollution is linked to increased incidence risks of atrial and ventricular arrhythmias. More focus should be shifted to the impact of air pollution on other arrhythmias besides atrial fibrillation.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 4","pages":"Pages 445-451"},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing bioactivity of environmental water samples filtered using nanomembrane technology and mammalian cell lines","authors":"Sarah E. Morgan , Lisa A. DeLouise","doi":"10.1016/j.eehl.2024.05.004","DOIUrl":"10.1016/j.eehl.2024.05.004","url":null,"abstract":"<div><p>This project reports on the use of a novel nanomembrane filtering technology to isolate and analyze the bioactivity of microplastic (MP)-containing debris from Lake Ontario water samples. Environmental MPs are a complex mixture of polymers and sorbed chemicals that are persistent and can exhibit a wide range of toxic effects. Since human exposure to MPs is unavoidable, it is necessary to characterize their bioactivity to assess potential health risks. This work seeks to quantify MP presence in the nearshore waters of Lake Ontario and begin to characterize the bioactivity of the filtrate containing MPs. We utilized silicon nitride (SiN) nanomembrane technology to isolate debris sized between 8 and 20 μm from lake water samples collected at various times and locations. MPs were identified with Nile red staining. Cell-based assays were conducted directly on the filtered debris to test for cell viability, aryl hydrocarbon receptor (AhR) activity, and interleukin 6 (IL-6) levels as a measure of proinflammatory response. All samples contained MPs. None of the isolated debris impacted cell viability. However, AhR activity and IL-6 levels varied over time. Additionally, no associations were observed between the amount of plastic and bioactivity. Observed differences in activity are likely due to variations in the physiochemical properties of debris between samples. Our results highlight the need for increased sampling to fully characterize the bioactivity of MPs in human cells and to elucidate the role that sample physiochemical and spatiotemporal properties play in this activity.</p></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 3","pages":"Pages 347-354"},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772985024000450/pdfft?md5=29bd23b5241cc8c21143e08879295925&pid=1-s2.0-S2772985024000450-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jia Jia , Qian Liu , E. Zhao , Xin Li , Xiong Xiong , Chenxi Wu
{"title":"Biofilm formation on microplastics and interactions with antibiotics, antibiotic resistance genes and pathogens in aquatic environment","authors":"Jia Jia , Qian Liu , E. Zhao , Xin Li , Xiong Xiong , Chenxi Wu","doi":"10.1016/j.eehl.2024.05.003","DOIUrl":"10.1016/j.eehl.2024.05.003","url":null,"abstract":"<div><div>Microplastics (MPs) in aquatic environments easily support biofilm development, which can interact with other environmental pollutants and act as harbors for microorganisms. Recently, numerous studies have investigated the fate and behavior of MP biofilms in aquatic environments, highlighting their roles in the spread of pathogens and antibiotic resistance genes (ARGs) to aquatic organisms and new habitats. The prevalence and effects of MP biofilms in aquatic environments have been extensively investigated in recent decades, and their behaviors in aquatic environments need to be synthesized systematically with updated information. This review aims to reveal the development of MP biofilm and its interactions with antibiotics, ARGs, and pathogens in aquatic environments. Recent research has shown that the adsorption capabilities of MPs to antibiotics are enhanced after the biofilm formation, and the adsorption of biofilms to antibiotics is biased towards chemisorption. ARGs and microorganisms, especially pathogens, are selectively enriched in biofilms and significantly different from those in surrounding waters. MP biofilm promotes the propagation of ARGs through horizontal gene transfer (HGT) and vertical gene transfer (VGT) and induces the emergence of antibiotic-resistant pathogens, resulting in increased threats to aquatic ecosystems and human health. Some future research needs and strategies in this review are also proposed to better understand the antibiotic resistance induced by MP biofilms in aquatic environments.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 4","pages":"Pages 516-528"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141138273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Yang , Lianzhen Li , Chen Tu , Ruijie Li , Yongming Luo
{"title":"Crop plants transport irregularly shaped mineral particles from root to shoot: Tracking and quantifying","authors":"Jie Yang , Lianzhen Li , Chen Tu , Ruijie Li , Yongming Luo","doi":"10.1016/j.eehl.2024.05.002","DOIUrl":"10.1016/j.eehl.2024.05.002","url":null,"abstract":"<div><div>Mineral particles, ubiquitous in soils, influence crop plant growth by carrying nutrients and pollutants. While the uptake of dissolved mineral nutrients is well-established, the direct incorporation of irregular mineral particles into plants remains unclear. This study investigated the uptake and transport of kaolin particles, representative of minerals, by wheat and lettuce seedlings using hydroponic and soil cultures. Covalent labeling and advanced microscopy revealed that kaolin enters root steles at lateral root emergence sites, followed by transport to shoots. Fluorescent dyes and lanthanum (La)-labeled kaolin particles demonstrated that wheat surpassed lettuce in kaolin uptake in hydroponics, but both plants showed similar levels of particles in the shoots. Translocation factors (TFs) for kaolin were significantly higher in soil (0.089 for wheat, 0.039 for lettuce) compared to hydroponics (0.001 for wheat, 0.003 for lettuce). These findings provide compelling evidence for the direct uptake and transport of kaolin particles in crop plants. This opens new avenues for research on the interactions between plant and mineral particles, including other colloidal particles, in terrestrial ecosystems.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 4","pages":"Pages 458-465"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exhalation metabolomics: A new force in revealing the impact of ozone pollution on respiratory health","authors":"","doi":"10.1016/j.eehl.2024.05.001","DOIUrl":"10.1016/j.eehl.2024.05.001","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 4","pages":"Pages 407-411"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141038350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanwei Liu , Hongwei Liu , Yingying Guo , Dawei Lu , Xingwang Hou , Jianbo Shi , Yongguang Yin , Yong Cai , Guibin Jiang
{"title":"Atmospheric Hg(0) dry deposition over environmental surfaces: Insights from mercury isotope fractionation","authors":"Yanwei Liu , Hongwei Liu , Yingying Guo , Dawei Lu , Xingwang Hou , Jianbo Shi , Yongguang Yin , Yong Cai , Guibin Jiang","doi":"10.1016/j.eehl.2024.04.009","DOIUrl":"10.1016/j.eehl.2024.04.009","url":null,"abstract":"<div><div>Atmospheric Hg(0) dry deposition is a vital process that significantly affects the global distribution and cycling of Hg. However, significant knowledge gaps and challenges remain in understanding atmospheric Hg(0) deposition and its subsequent post-deposition processes. Hg isotope fractionation has emerged as the most powerful tool for evaluating the impact of atmospheric Hg(0) deposition and unraveling key processes associated with it. By focusing on Hg isotope fractionation processes, Hg isotopic compositions, and influencing factors, this review presents current knowledge, recent advances, and new insights into atmospheric Hg(0) deposition and post-deposition processes over vegetation, soil, snow, and water surfaces. This review also points out the knowledge gaps pertaining to atmospheric Hg(0) deposition and highlights the need for further investigation into the associated processes, mechanisms, isotope fractionation, and modeling. Further research into Hg isotope fractionation in atmospheric Hg(0) deposition and post-deposition processes will advance source and process tracing, paleoclimate reconstruction, and the modeling of Hg isotope distribution on regional and global scales.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 4","pages":"Pages 543-555"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141029850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early-life exposure to per- and polyfluoroalkyl substances: Analysis of levels, health risk and binding abilities to transport proteins","authors":"","doi":"10.1016/j.eehl.2024.04.007","DOIUrl":"10.1016/j.eehl.2024.04.007","url":null,"abstract":"<div><p>Per- and polyfluoroalkyl substances (PFAS) can pass through the placenta and adversely affect fetal development. However, there is a lack of comparison of legacy and emerging PFAS levels among different biosamples in pregnant women and their offspring. This study, based on the Shanghai Maternal–Child Pairs Cohort, analyzed the concentrations of 16 PFAS in the maternal serum, cord serum, and breast milk samples from 1,076 mother-child pairs. The placental and breastfeeding transfer efficiencies of PFAS were determined in maternal-cord and maternal-milk pairs, respectively. The binding affinities of PFAS to five transporters were simulated using molecular docking. The results suggested that PFAS were frequently detected in different biosamples. The median concentration of perfluorooctane sulfonate (PFOS) was the highest at 8.85 ng/mL, followed by perfluorooctanoic acid (PFOA) at 7.13 ng/mL and 6:2 chlorinated polyfluorinated ether sulfonate at 5.59 ng/mL in maternal serum. The median concentrations of PFOA were highest in cord serum (4.23 ng/mL) and breast milk (1.08 ng/mL). PFAS demonstrated higher placental than breastfeeding transfer efficiencies. The transfer efficiencies and the binding affinities of most PFAS to proteins exhibited alkyl chain length-dependent patterns. Furthermore, we comprehensively assessed the estimated daily intakes (EDIs) of PFAS in breastfeeding infants of different age groups and used the hazard quotient (HQ) to characterize the potential health risk. EDIs decreased with infant age, and PFOS had higher HQs than PFOA. These findings highlight the significance of considering PFAS exposure, transfer mechanism, and health risks resulting from breast milk intake in early life.</p></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 3","pages":"Pages 308-316"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772985024000358/pdfft?md5=f0aa07aef05eacc7d828f2dfe88eb298&pid=1-s2.0-S2772985024000358-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prenatal ozone exposure is associated with children overweight and obesity: Evidence from the Shanghai Maternal–Child Pairs Cohort","authors":"","doi":"10.1016/j.eehl.2024.04.008","DOIUrl":"10.1016/j.eehl.2024.04.008","url":null,"abstract":"<div><div>Prenatal ozone (O<sub>3</sub>) exposure may disrupt normal offspring growth. However, epidemiological evidence that prenatal O<sub>3</sub> exposure affects the physical development of offspring early in life is far from adequate. A total of 4909 maternal–child pairs from the Shanghai Maternal–Child Pairs Cohort were included. A high-resolution random forest model was utilized to evaluate prenatal exposure levels of O<sub>3</sub> based on the home addresses of pregnant women. Group-based trajectory and mixed-effects models were used to assess associations between prenatal O<sub>3</sub> exposure and physical parameters. Each 10 μg/m³ increase in O<sub>3</sub> concentration was associated with 0.084, 0.048, and 0.082-unit increases in body mass index (BMI) for age Z score (BAZ), weight for age Z score (WAZ), and weight for length Z score (WLZ), respectively. Specifically, a 10 μg/m³ increase in O<sub>3</sub> concentration was linked to a 1.208-fold and 1.209-fold increase in the elevated-increasing group for the BAZ and WLZ trajectories, respectively. Moreover, each 10 μg/m³ increases in prenatal O<sub>3</sub> was associated with a 1.396-fold and 0.786-fold increase in the risk of BAZ- and length for age Z score (LAZ)-accelerated growth, respectively. Furthermore, a 10 μg/m³ increase in prenatal O<sub>3</sub> was linked to a 1.355-fold increase in the risk of overweight and obesity (OAO). Our study revealed that prenatal O<sub>3</sub> exposure is associated with accelerated BMI gain or decelerated body length gain in the early life of children. Prenatal O<sub>3</sub> may also increase the risk of OAO in children for the first two years.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 4","pages":"Pages 436-444"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Temilayo Adeyeye , Tabassum Zarina Insaf , Catherine Adler , Victoria Wagner , Anisa Proj , Susan McCauley
{"title":"A census tract-level assessment of social determinants of health, traffic exposure, and asthma exacerbations in New York State's Medicaid Population (2005–2015)","authors":"Temilayo Adeyeye , Tabassum Zarina Insaf , Catherine Adler , Victoria Wagner , Anisa Proj , Susan McCauley","doi":"10.1016/j.eehl.2024.04.005","DOIUrl":"10.1016/j.eehl.2024.04.005","url":null,"abstract":"<div><p>This study aims to evaluate the association between social determinants, environmental exposure metrics, and the risk of asthma emergency department (ED) visits in the New York State (NYS) Medicaid population using small-area analysis. Traffic densities for each census tract in NYS were calculated using the length of road segments within each tract and total area of the tract to produce a measure of average number of vehicles per square meter per day. Data on social determinants of health including internal and external environments and other demographic factors were obtained from various sources. Poisson regression analyses were conducted to identify significant factors associated with asthma ED visits in Medicaid claim and encounter data for years 2005–2015. High traffic density in NYS excluding New York City (NYC) correlated with increased risk of asthma ED visits (RR 1.69; 95% CI: 1.42, 2.00), mitigated by adjusting for environmental and social determinants (RR 1.00; 95% CI: 0.85, 1.19). Similar trends were observed in NYC only (RR 1.19; 95% CI: 1.00, 1.41), with the adjusted risk remaining elevated (RR 1.14; 95% CI: 0.98, 1.33) albeit not statistically significant. Living in census tracts with high concentrated disadvantage index, high proportions of minorities, and less green space predicted higher asthma ED visits. We mapped predicted rates and model residuals to identify areas of high risk. Our results support previous findings that environmental and social risk factors in poor and urban areas contribute to asthma exacerbations in the NYS Medicaid population, even if they may not necessarily contribute to its development.</p></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"3 3","pages":"Pages 300-307"},"PeriodicalIF":0.0,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772985024000334/pdfft?md5=f9ba009260ea381bf7df2a14a2ec4d21&pid=1-s2.0-S2772985024000334-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}