Eco-Environment & Health最新文献

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Reinterpretation of a new ChatGPT-empowered, easy-to-use machine learning paradigm: An aide-memoire 重新诠释一个新的chatgpt授权,易于使用的机器学习范式:备忘录
Eco-Environment & Health Pub Date : 2025-05-21 DOI: 10.1016/j.eehl.2025.100156
Ilker Sengul , Demet Sengul
{"title":"Reinterpretation of a new ChatGPT-empowered, easy-to-use machine learning paradigm: An aide-memoire","authors":"Ilker Sengul , Demet Sengul","doi":"10.1016/j.eehl.2025.100156","DOIUrl":"10.1016/j.eehl.2025.100156","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100156"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144167316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cadmium accumulation in wheat grain: Accumulation models and soil thresholds for safe production 小麦籽粒镉积累:积累模型和安全生产的土壤阈值
Eco-Environment & Health Pub Date : 2025-05-14 DOI: 10.1016/j.eehl.2025.100154
Lu Lin , Xiaopeng Zhao , Yumeng Li , Jingbo Ling , Jinghua Ren , Qilin Liao , Dongmei Zhou , Xueyuan Gu
{"title":"Cadmium accumulation in wheat grain: Accumulation models and soil thresholds for safe production","authors":"Lu Lin ,&nbsp;Xiaopeng Zhao ,&nbsp;Yumeng Li ,&nbsp;Jingbo Ling ,&nbsp;Jinghua Ren ,&nbsp;Qilin Liao ,&nbsp;Dongmei Zhou ,&nbsp;Xueyuan Gu","doi":"10.1016/j.eehl.2025.100154","DOIUrl":"10.1016/j.eehl.2025.100154","url":null,"abstract":"<div><div>The high cadmium (Cd) accumulation ability of wheat has garnered significant attention in China. It is crucial to identify the key factors affecting Cd accumulation in wheat and to develop predictive models to derive the threshold concentration of Cd in soil for safe wheat production. A total of 311 soil–wheat paired datasets were collected from both literature and field surveys in China, in which the ranges of Cd in soil and wheat grain were 0.068–13.500 ​mg/kg and 0.006–2.190 ​mg/kg, respectively. Correlation analyses and Partial Least Squares Path Model indicated that soil Cd, soil pH, and CEC together controlled the transfer of Cd from soil to wheat. Multiple linear regression models were successfully established using soil Cd contents or bioavailable Cd (extracted by CaCl<sub>2</sub> or calculated using a multi-surface speciation model), pH, and CEC as input variables to predict wheat Cd (RMSE ​= ​0.242–0.327, MAE ​= ​0.188–0.249). Furthermore, the Extreme Random Tree model (RMSE ​= ​0.221, MAE ​= ​0.165) outperformed the other seven machine learning algorithms. The thresholds for both soil total Cd and bioavailable Cd for safe wheat production were further back-calculated according to the permissible value of Cd in wheat grain, which demonstrated enhanced protection accuracy compared to the current soil quality standard. Our findings facilitate a quantitative assessment of Cd accumulation risk in wheat, offering a valuable reference for the safe production of wheat.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100154"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanistic insights into nitrogen removal performance and electron competition with mixed electron donor supply in a biofilm electrode reactor 生物膜电极反应器中混合电子供体供应的氮去除性能和电子竞争机理研究
Eco-Environment & Health Pub Date : 2025-05-07 DOI: 10.1016/j.eehl.2025.100153
Xin Yuan, Chunfang Chao, Jiaojiao Niu, Jinxin Song, Yiwen Liu, Siyuan Zhai, Yingxin Zhao
{"title":"Mechanistic insights into nitrogen removal performance and electron competition with mixed electron donor supply in a biofilm electrode reactor","authors":"Xin Yuan,&nbsp;Chunfang Chao,&nbsp;Jiaojiao Niu,&nbsp;Jinxin Song,&nbsp;Yiwen Liu,&nbsp;Siyuan Zhai,&nbsp;Yingxin Zhao","doi":"10.1016/j.eehl.2025.100153","DOIUrl":"10.1016/j.eehl.2025.100153","url":null,"abstract":"<div><div>In this study, a unique electrode configuration in the form of an “inverted T” was developed in the biofilm electrode reactor (BER), enabling superior nitrogen removal via the synergistic effect of hydrogen autotrophic denitrification and heterotrophic denitrification. In contrast to the sole heterotrophic denitrification in the biofilm reactor (BR), weak electric stimulation in the BER system promoted <em>in situ</em> hydrogen production as well as electron transport and utilization, resulting in a notable 20% improvement in <span><math><mrow><msubsup><mtext>NO</mtext><mn>3</mn><mo>-</mo></msubsup></mrow></math></span> removal efficiency for both influent COD/N ratios. Conversely, notable <span><math><mrow><msubsup><mtext>NO</mtext><mn>2</mn><mo>-</mo></msubsup></mrow></math></span> accumulation occurred under both COD/N ratios, with concentrations ranging from 6.0 to 8.0 ​mg/L. The enrichment of non-heterotrophic denitrifiers, such as <em>Thermomonas, Pelomonas,</em> and <em>Hydrogenophaga,</em> was observed in the BER with a relative abundance exceeding 1.0%, contributing to the hydrogen autotrophic denitrification pathway. Based on the outcomes of the multiple electron donor utilization in the coexistence of different electron acceptor combinations, despite H<sub>2</sub> serving as an additional electron donor in the BER, electron competition was still detectable. Notably, nitrite reductase (Nir) emerged as the weakest competitor, resulting in a constrained <span><math><mrow><msubsup><mtext>NO</mtext><mn>2</mn><mo>-</mo></msubsup></mrow></math></span> reduction capacity. Based on the analysis of the electron competition characteristic, the potential <span><math><mrow><msubsup><mtext>NO</mtext><mn>3</mn><mo>-</mo></msubsup></mrow></math></span> metabolic pathway in the BER system was primarily driven by heterotrophic denitrification processes. The introduced electricity in the BER system was favorable for facilitating nitrogen removal through <em>in situ</em> production of hydrogen, direct supply of electrons from the electrode, improvement of functional microbial activity, and enhancement of enzymatic activity.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100153"},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blue Hg Dilemma and implications for Nature-based Solution and One Health Approach 蓝汞困境及其对基于自然的解决方案和一个健康方法的影响
Eco-Environment & Health Pub Date : 2025-05-06 DOI: 10.1016/j.eehl.2025.100152
Zhijia Ci
{"title":"Blue Hg Dilemma and implications for Nature-based Solution and One Health Approach","authors":"Zhijia Ci","doi":"10.1016/j.eehl.2025.100152","DOIUrl":"10.1016/j.eehl.2025.100152","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100152"},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Park pricing in theory and practice and implications for ecosystem and human health 公园定价理论与实践及其对生态系统和人类健康的影响
Eco-Environment & Health Pub Date : 2025-04-28 DOI: 10.1016/j.eehl.2025.100151
Krishnal Thirumarpan , Elizabeth J.Z. Robinson
{"title":"Park pricing in theory and practice and implications for ecosystem and human health","authors":"Krishnal Thirumarpan ,&nbsp;Elizabeth J.Z. Robinson","doi":"10.1016/j.eehl.2025.100151","DOIUrl":"10.1016/j.eehl.2025.100151","url":null,"abstract":"<div><div>Though a rich literature addresses the theory of park pricing, less attention has been paid to the practical realities. In this narrative review article, we ask why the setting of national park entry fees varies in practice, and we link this back to the underlying theory, the empirical academic literature, and practical realities. Park entry pricing strategies tend to differ considerably in higher and lower-income countries, reflecting practical realities of how to fund a national park system. Parks in higher-income countries are often free at the point of entry, consistent with the efficient pricing of global public goods. In contrast, differential pricing for local and foreign tourists is common in lower-income countries, an example of price discrimination that increases overall park revenues. We highlight a number of areas for further research. First, the concept of fairness and equitable access is an important practical consideration, linked to who benefits from visiting parks versus who pays, but much more attention needs to be paid to this in the literature. Second, while there is increasing recognition of the importance of green spaces for health and well-being, the literature largely ignores how health considerations might influence park entry fees, suggesting that more research is needed at the nexus of pricing, health and well-being, and equitable access. Finally, many lower-income countries that have a high dependence on foreign visitor fees to fund their national park systems are vulnerable to global shocks, suggesting research is needed into how to increase long-term sustainability of funding sources.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100151"},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatio-temporal dynamics of human-induced carbon emissions in Southeast Asia (1992–2022) based on nighttime light 基于夜间光照的东南亚人为碳排放时空动态
Eco-Environment & Health Pub Date : 2025-04-26 DOI: 10.1016/j.eehl.2025.100150
Chaoqing Huang , Qian Wu , Yujie Chen , MinhThu Nguyen , Bin Chen , Song Hong , Chao He
{"title":"Spatio-temporal dynamics of human-induced carbon emissions in Southeast Asia (1992–2022) based on nighttime light","authors":"Chaoqing Huang ,&nbsp;Qian Wu ,&nbsp;Yujie Chen ,&nbsp;MinhThu Nguyen ,&nbsp;Bin Chen ,&nbsp;Song Hong ,&nbsp;Chao He","doi":"10.1016/j.eehl.2025.100150","DOIUrl":"10.1016/j.eehl.2025.100150","url":null,"abstract":"<div><div>Understanding regional carbon emissions from human activities, particularly their spatio-temporal patterns, is essential for implementing decarbonization strategies and cultivating a low-carbon economy. This study develops a spatial visualization model to estimate carbon emissions in Southeast Asia using calibrated nighttime light data, with DMSP-OLS (Defense Meteorological Satellite Program Operational Linescan System) and NPP-VIIRS (National Polar-orbiting Partnership Visible Infrared Imaging Radiometer Suite) standardized through polynomial regression and machine learning to ensure consistency. Emissions in Southeast Asia increased by 2.51 times from 1992 to 2022, shifting from gradual to rapid growth. Validation against Open-source Data Inventory for Anthropogenic CO<sub>2</sub> (ODIAC) and Emissions Database for Global Atmospheric Research (EDGAR) shows strong agreement in high-emission urban areas but discrepancies in low-emission rural regions due to data sparsity and satellite sensor limits. Spatial analysis reveals that major Southeast Asian cities and their peripheries exhibit robust, sustained growth, while rural, less-developed areas show slower trends, highlighting persistent urban-rural disparities. These urban regions demonstrate a “circular economy advantage”, where per-unit-area carbon emissions steadily rise in economically advantageous zones. Despite high model accuracy, uncertainties persist due to variations in regional economic activities and the limitations of satellite-based emission proxies. Forecasts suggest elevated emission levels in major cities will continue, while changes in other areas remain relatively minimal. Consequently, achieving a low-carbon economy in Southeast Asia requires a top-down approach, emphasizing infrastructure enhancement, resource and energy optimization, and fostering a sustainable, circular socio-economic system.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100150"},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of greenness with incidence of cardiovascular disease in China: Evidence from the China Kadoorie Biobank prospective cohort study with 0.5 million adults 绿色与中国心血管疾病发病率的关系:来自中国嘉道理生物库的50万成年人前瞻性队列研究的证据
Eco-Environment & Health Pub Date : 2025-04-24 DOI: 10.1016/j.eehl.2025.100148
Xia Meng , Lina Zhang , Ka Hung Chan , Jun Lv , Hubert Lam , Cong Liu , Renjie Chen , Christiana Kartsonaki , Neil Wright , Huaidong Du , Ling Yang , Yiping Chen , Dianjianyi Sun , Pei Pei , Canqing Yu , Haidong Kan , Zhengming Chen , Liming Li , China Kadoorie Biobank Collaborative Group
{"title":"Association of greenness with incidence of cardiovascular disease in China: Evidence from the China Kadoorie Biobank prospective cohort study with 0.5 million adults","authors":"Xia Meng ,&nbsp;Lina Zhang ,&nbsp;Ka Hung Chan ,&nbsp;Jun Lv ,&nbsp;Hubert Lam ,&nbsp;Cong Liu ,&nbsp;Renjie Chen ,&nbsp;Christiana Kartsonaki ,&nbsp;Neil Wright ,&nbsp;Huaidong Du ,&nbsp;Ling Yang ,&nbsp;Yiping Chen ,&nbsp;Dianjianyi Sun ,&nbsp;Pei Pei ,&nbsp;Canqing Yu ,&nbsp;Haidong Kan ,&nbsp;Zhengming Chen ,&nbsp;Liming Li ,&nbsp;China Kadoorie Biobank Collaborative Group","doi":"10.1016/j.eehl.2025.100148","DOIUrl":"10.1016/j.eehl.2025.100148","url":null,"abstract":"<div><div>Prospective evidence on the relationship of greenness with cardiovascular disease (CVD) incidence is limited in low- and middle-income countries. In 512,691 participants of the China Kadoorie Biobank cohort across 10 regions in China, we calculated the levels of greenness exposure based on satellite-retrieved Normalized Difference Vegetation Index (NDVI) data. Annual maximum NDVI (NDVI<sub>max</sub>) values were estimated within 500 ​m and 1000 ​m buffers around the locations for the participants during the follow-up periods. Record linkages to healthcare databases provided incidence data of total CVD, ischemic heart disease and stroke during 2005–2017. Time-varying Cox proportional hazards regression was used to assess the associations between greenness exposure and CVD incidence. After 5.08 million person-years of follow-up, 148,032 incident CVD events were recorded. The overall average level of NDVI<sub>max</sub> was 0.543 for all participants. We observed significant inverse associations of greenness with the incidence of CVD and its subtypes. Specifically, the hazard ratio for total CVD incidence was 0.976 (95% confidence interval: 0.958, 0.994) per 0.1 increase in NDVI<sub>max</sub> within a 500 ​m buffer. As the 5 rural regions have achieved the WHO recommended greenness goal values, we compared the greenness levels in the 5 urban regions with the WHO's goal for greenness and found that, on average, 3.81% of total CVD incidence might be averted if the recommended greenness values could be achieved. Exposure to a higher level of greenness was associated with a lower risk of CVD incidence in Chinese adults.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Embracing global biodiversity toward a better planet 拥抱全球生物多样性,共创美好地球
Eco-Environment & Health Pub Date : 2025-04-22 DOI: 10.1016/j.eehl.2025.100147
Haigen Xu , Richard D. Gregory , Yun Cao , Riquan Zhang , Lirong Zhang , Michael Gill , Dandan Yu , Jianfeng Yi , Wei Liu , Hongmei Lin
{"title":"Embracing global biodiversity toward a better planet","authors":"Haigen Xu ,&nbsp;Richard D. Gregory ,&nbsp;Yun Cao ,&nbsp;Riquan Zhang ,&nbsp;Lirong Zhang ,&nbsp;Michael Gill ,&nbsp;Dandan Yu ,&nbsp;Jianfeng Yi ,&nbsp;Wei Liu ,&nbsp;Hongmei Lin","doi":"10.1016/j.eehl.2025.100147","DOIUrl":"10.1016/j.eehl.2025.100147","url":null,"abstract":"<div><div>Global biodiversity is the most essential component of the planet, and the Kunming-Montreal Global Biodiversity Framework (GBF) has been unanimously adopted by 196 parties worldwide in 2022 to achieve the global vision of a world of living in harmony with nature by 2050. Of particular importance is the timely update of the National Biodiversity Strategies and Action Plans (NBSAPs) and/or National Targets aligned with the GBF before the sixteenth meeting of the Conference of the Parties (COP16) to the Convention on Biological Diversity. Upon comprehensive evaluation of updated NBSAPs of 47 parties and updated national targets of 126 parties, we proposed pathways that could better inform the updating processes. First, the essential elements of the goals and targets of the GBF applicable to national circumstances should be equivalently translated into national policies and instruments. Second, when specific national circumstances do not match with those essential elements, parties need to determine their own national biodiversity targets based on their situation but in a way that maintains and reflects the ambition of the GBF. Furthermore, the key factors that promote the success of biodiversity conservation are highlighted in terms of the target alignment with the GBF, the ownership enhancement, and the capacity building. We anticipate that these measures could facilitate immediate actions to update the NBSAPs to align with the GBF at the highest level while remaining cost-effectiveness.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100147"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plastics tracking strategy: Plastic-related small molecules as chemical fingerprints 塑料追踪策略:塑料相关小分子作为化学指纹
Eco-Environment & Health Pub Date : 2025-04-22 DOI: 10.1016/j.eehl.2025.100149
Hongtao Liu , Yuna Li , Yongzheng Ma , Ying Zhang , Zhiguang Niu
{"title":"Plastics tracking strategy: Plastic-related small molecules as chemical fingerprints","authors":"Hongtao Liu ,&nbsp;Yuna Li ,&nbsp;Yongzheng Ma ,&nbsp;Ying Zhang ,&nbsp;Zhiguang Niu","doi":"10.1016/j.eehl.2025.100149","DOIUrl":"10.1016/j.eehl.2025.100149","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term exposure to low-level ambient BTEX and site-specific cancer risk: A national cohort study in the UK Biobank 长期暴露于低水平环境BTEX和特定部位的癌症风险:英国生物银行的一项国家队列研究
Eco-Environment & Health Pub Date : 2025-04-09 DOI: 10.1016/j.eehl.2025.100146
Kexin Yu , Ying Xiong , Renjie Chen , Jing Cai , Yaoxian Huang , Haidong Kan
{"title":"Long-term exposure to low-level ambient BTEX and site-specific cancer risk: A national cohort study in the UK Biobank","authors":"Kexin Yu ,&nbsp;Ying Xiong ,&nbsp;Renjie Chen ,&nbsp;Jing Cai ,&nbsp;Yaoxian Huang ,&nbsp;Haidong Kan","doi":"10.1016/j.eehl.2025.100146","DOIUrl":"10.1016/j.eehl.2025.100146","url":null,"abstract":"<div><div>Benzene, toluene, ethylbenzene, and xylene (BTEX) have been associated with certain cancers in the occupational population. This study aimed to investigate the associations between low-level ambient BTEX exposure and cancer risks in the general population. We leveraged data from the UK Biobank and included individuals free of cancer at 2006–2010 baseline. Annual concentrations of BTEX were estimated using a chemistry-climate model, and the associations between BTEX and incident overall and 18 site-specific cancers were investigated with Cox proportional hazard models. We also fitted restricted cubic splines to explore the exposure-response relationships. The study sample comprised 409,579 participants [mean age 56.2 (8.11) years; 219,315 (53.5%) females]. Over a mean (SD) follow-up period of 11.2 (2.64) years (4,597,164 person-years), 60,777 overall incident cancer cases occurred. The results showed significant associations between overall cancers and benzene [HR 1.93 (95% CI: 1.89, 1.96)], toluene [1.25 (1.23, 1.26)] and xylene [1.11 (1.10, 1.12)]. Benzene and toluene were associated with a higher risk of 18 site-specific cancers. For xylenes (a summation of ethylbenzene, m/p-xylene, and o-xylene in the model), significant associations with multiple myeloma, hepatobiliary tract, thyroid, or connective soft tissue were not observed. Exposure-response curves suggested a higher risk of overall cancer beyond the benzene threshold. For toluene and xylene, there was no threshold or plateau across the range of exposures. This large-scale prospective cohort study demonstrates that long-term exposure to low-level ambient BTEX could increase the risk of overall and site-specific cancers in the general population.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 2","pages":"Article 100146"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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