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Engineered protein nanofibrils for chain-integrated water treatment: From source monitoring to end-point purification 用于链集成水处理的工程蛋白纳米原纤维:从源头监测到终点净化
IF 13.4
Eco-Environment & Health Pub Date : 2026-09-01 Epub Date: 2026-08-24 DOI: 10.1016/j.eehl.2026.100273
Yiwei Liu, Zhengzheng Zhao, Yang Wu, Min Long, Xiong Zheng, Yinguang Chen
{"title":"Engineered protein nanofibrils for chain-integrated water treatment: From source monitoring to end-point purification","authors":"Yiwei Liu,&nbsp;Zhengzheng Zhao,&nbsp;Yang Wu,&nbsp;Min Long,&nbsp;Xiong Zheng,&nbsp;Yinguang Chen","doi":"10.1016/j.eehl.2026.100273","DOIUrl":"10.1016/j.eehl.2026.100273","url":null,"abstract":"<div><div>Escalating complexity in water pollution has catalyzed a shift toward chain-integrated management, encompassing source monitoring, targeted removal, and end-point purification. Protein nanofibrils (PNFs), self-assembled from abundant proteins, are ideal candidates for these challenges due to their rich functional groups, mild synthesis, and tunability. This review examines PNFs’ potential in chain-integrated water treatment technologies. First, the evolution of PNFs reveals their advantages over conventional nanomaterials such as cellulose nanofibrils and carbon nanotubes, including simpler preparation methods, superior physicochemical properties, and versatile functionalization capabilities. Second, PNFs serve multifunctional roles across the water treatment chain: as sensitive biosensor components for contaminant detection, selective adsorbents for pollutant removal, stable catalyst supports for degradation reactions, and effective membrane modifiers for filtration enhancement. The exceptional performance of PNFs results from abundant functional groups and controllable surface charge, which provide binding sites for contaminants and attachment points for functional materials, as well as their high aspect ratio that prevents nanoparticle aggregation while maintaining catalytic efficiency. Despite their commercial emergence as adsorbents, PNF-based systems face key bottlenecks, including limited biosensing selectivity, elusive adsorption mechanisms, and inadequate stability for catalysis. Future research directions should focus on developing interference-resistant binding strategies, optimizing macrostructure preparation, creating stable catalytic systems, and advancing structural analysis through molecular engineering approaches. This comprehensive review provides insights into these novel biomaterials and their potential in next-generation water treatment technologies.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 3","pages":"Article 100273"},"PeriodicalIF":13.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148934892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stabilized sand seas facing climate threats need health baselines now 面临气候威胁的稳定沙海现在需要健康基线
IF 13.4
Eco-Environment & Health Pub Date : 2026-09-01 Epub Date: 2026-08-22 DOI: 10.1016/j.eehl.2026.100272
Shivukumar Rakkasagi, Dorit Nitzan, Shimrit Maman
{"title":"Stabilized sand seas facing climate threats need health baselines now","authors":"Shivukumar Rakkasagi,&nbsp;Dorit Nitzan,&nbsp;Shimrit Maman","doi":"10.1016/j.eehl.2026.100272","DOIUrl":"10.1016/j.eehl.2026.100272","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 3","pages":"Article 100272"},"PeriodicalIF":13.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148934893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling the increasing burden of allergies: Spatiotemporal dynamics of pollen allergy risk in China 揭示日益增加的过敏负担:中国花粉过敏风险的时空动态
IF 13.4
Eco-Environment & Health Pub Date : 2026-09-01 Epub Date: 2026-07-30 DOI: 10.1016/j.eehl.2026.100267
Bo Cao, Chengke Bai, Kunyi Wu, Ting La, Nan Xu, Lianjin Liu, Xiaofang Zhou, Chong Chen, Tiantian Bin, Shan Feng, Yali Zhang, Guishuang Li
{"title":"Unraveling the increasing burden of allergies: Spatiotemporal dynamics of pollen allergy risk in China","authors":"Bo Cao,&nbsp;Chengke Bai,&nbsp;Kunyi Wu,&nbsp;Ting La,&nbsp;Nan Xu,&nbsp;Lianjin Liu,&nbsp;Xiaofang Zhou,&nbsp;Chong Chen,&nbsp;Tiantian Bin,&nbsp;Shan Feng,&nbsp;Yali Zhang,&nbsp;Guishuang Li","doi":"10.1016/j.eehl.2026.100267","DOIUrl":"10.1016/j.eehl.2026.100267","url":null,"abstract":"<div><div>Pollen allergies have increased significantly worldwide in recent years. However, its mechanism from an ecological perspective has not been fully elucidated. Here, we report, for the first time, the spatial distribution patterns of artificially planted allergenic plants (APAPs) and naturally distributed allergenic plants (NDAPs) in China. Field investigations (2007–2023) and ecological niche modeling efforts revealed that APAPs are concentrated in economically developed urban regions, while NDAPs exhibit distinct ecological niches across climatic gradients. Further risk analysis indicates that pollen allergy risk correlates significantly with socio-economic and environmental factors, demonstrating that regions southeast of the Heihe-Tengchong Line are particularly vulnerable. Future climate scenarios show a substantial increase in NDAP distributions and associated allergy risks by 2100, highlighting a critical expansion of high-suitability areas for allergenic plants. Further monitoring across diverse climatic regions elucidates the ecological mechanisms driving increased pollen allergies, with warmer temperatures leading to prolonged flowering periods and higher pollen counts. These findings highlight the urgent need for adaptive public health strategies to mitigate the impact of pollen allergies in a rapidly changing environment, offering critical insights for the development of effective intervention programs to address global climate challenges.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 3","pages":"Article 100267"},"PeriodicalIF":13.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148934894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Policy and advanced monitoring synergies to tackle ammonia emission impacts 解决氨排放影响的政策和先进监测协同效应
IF 17.6
Eco-Environment & Health Pub Date : 2026-06-01 Epub Date: 2026-05-20 DOI: 10.1016/j.eehl.2026.100248
Yajie Shu , Tian Hu , Ming Zhou
{"title":"Policy and advanced monitoring synergies to tackle ammonia emission impacts","authors":"Yajie Shu ,&nbsp;Tian Hu ,&nbsp;Ming Zhou","doi":"10.1016/j.eehl.2026.100248","DOIUrl":"10.1016/j.eehl.2026.100248","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 2","pages":"Article 100248"},"PeriodicalIF":17.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shaping of microbial community structure and function by effluent-derived dissolved organic matter in a receiving river across seasons 跨季节接收河流中流出的溶解有机物对微生物群落结构和功能的影响
IF 17.6
Eco-Environment & Health Pub Date : 2026-06-01 Epub Date: 2026-05-23 DOI: 10.1016/j.eehl.2026.100251
Bo Shao , Zhengyu Wu , Haoran Peng , Qing Yang , Meiqi Huang , Qirui Wang , Yiwen Liu , Wei He , Yingxin Zhao , Xiaoyu Cui , Hongyang Cui , Yindong Tong
{"title":"Shaping of microbial community structure and function by effluent-derived dissolved organic matter in a receiving river across seasons","authors":"Bo Shao ,&nbsp;Zhengyu Wu ,&nbsp;Haoran Peng ,&nbsp;Qing Yang ,&nbsp;Meiqi Huang ,&nbsp;Qirui Wang ,&nbsp;Yiwen Liu ,&nbsp;Wei He ,&nbsp;Yingxin Zhao ,&nbsp;Xiaoyu Cui ,&nbsp;Hongyang Cui ,&nbsp;Yindong Tong","doi":"10.1016/j.eehl.2026.100251","DOIUrl":"10.1016/j.eehl.2026.100251","url":null,"abstract":"<div><div>Wastewater treatment plant (WWTP) effluent is a significant source of environmental impacts, introducing substantial dissolved organic matter (DOM) and nutrients into receiving waters. However, the specific role of effluent-derived DOM (EDOM) in shaping microbial community structure and key metabolic functions remains insufficiently understood. We systematically explored the effects of EDOM on the seasonal dynamics of bacterial communities in effluent-receiving waters in a typical water-scarce region of North China. Our results revealed that WWTP effluent input significantly altered DOM characteristics, shifting them toward greater humification, increased recalcitrance, lower molecular mass, and simpler structure, against a background of elevated nutrient levels. The interplay between transformed EDOM and resident microorganisms collectively restructured the bacterial community and its potential metabolic functions. These changes included (i) increased taxonomic richness and a more specialized community composition; (ii) enhanced microbial network complexity with a polycentric architecture dominated by DOM components; (iii) seasonal convergence of microbial network structure, as strong EDOM-driven interactions in the dry season were attenuated by wet season hydrology; and (iv) strengthened coupling between DOM molecular traits and biogeochemical cycling potential. Crucially, EDOM was identified as the key driver controlling microbial richness and core metabolic processes, with its influence exhibiting significant seasonal dynamics across the carbon, nitrogen, and sulfur cycles. While current Chinese wastewater discharge standards regulate nutrient inputs, they lack consideration of ecological risks posed by EDOM fractions and their dynamic interactions with microorganisms. Our findings highlight the need to integrate EDOM characteristics into effluent risk assessments to improve WWTP discharge standards.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 2","pages":"Article 100251"},"PeriodicalIF":17.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinct demethylation pathways of rice- and fish-derived methylmercury in pregnant women revealed by compound-specific isotope analysis 化合物特异性同位素分析揭示了孕妇体内大米和鱼类来源的甲基汞的不同去甲基化途径
IF 17.6
Eco-Environment & Health Pub Date : 2026-03-01 Epub Date: 2025-12-24 DOI: 10.1016/j.eehl.2025.100213
Chuyan Lai , Shaochen Yang , Ruolan Li , Huifang Jiang , Rasheed Mohammed Abdul , Ping Li , Bo Wang , Xinbin Feng
{"title":"Distinct demethylation pathways of rice- and fish-derived methylmercury in pregnant women revealed by compound-specific isotope analysis","authors":"Chuyan Lai ,&nbsp;Shaochen Yang ,&nbsp;Ruolan Li ,&nbsp;Huifang Jiang ,&nbsp;Rasheed Mohammed Abdul ,&nbsp;Ping Li ,&nbsp;Bo Wang ,&nbsp;Xinbin Feng","doi":"10.1016/j.eehl.2025.100213","DOIUrl":"10.1016/j.eehl.2025.100213","url":null,"abstract":"<div><div>Understanding mercury (Hg) metabolism and exposure pathways in pregnant women is essential for protecting fetal health. However, most previous studies have relied primarily on Hg concentrations in single biomarkers, limiting insight into <em>in vivo</em> metabolic differences and maternal–fetal transfer, especially regarding source-specific MeHg metabolism. This study applies compound-specific stable isotope analysis to investigate total Hg (THg) and methylmercury (MeHg) concentrations and isotopic signatures in rice and maternal biomarkers from the Wanshan Hg mining area, China. Even after remediation, THg in all cord blood samples still exceeded the U.S. EPA recommended limit. Widespread mass-dependent fractionation (MDF) was observed across different biomarkers. The MDF of THg was driven by internal redistribution and demethylation of MeHg, while the MDF of MeHg specifically reflected metabolic demethylation processes in the gut and brain. In contrast, no mass-independent fractionation (MIF) was observed during maternal or transplacental THg transfer, suggesting that Δ<sup>199</sup>Hg values in maternal biomarkers reflect food-source signals. This study identifies the biomarker-specific contribution of dietary sources: MeHg isotope mixing models revealed that rice contributed a higher proportion of Hg in maternal blood than in hair, comparable to that in placenta and cord blood. Comparisons with previously reported fish-derived MeHg isotopes suggest that rice-derived MeHg undergoes preferential demethylation and elimination, highlighting the complexity of <em>in vivo</em> Hg dynamics. The use of both THg and MeHg isotopes in biomarkers enables more precise tracing of dietary Hg sources. These findings highlight the value of multi-biomarker isotope analysis for tracing Hg sources and improving exposure assessments.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 1","pages":"Article 100213"},"PeriodicalIF":17.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal cadmium exposure and male infertility in mice: A multi-generational mechanistic study 小鼠产前镉暴露与雄性不育:一项多代机制研究
IF 17.6
Eco-Environment & Health Pub Date : 2026-03-01 Epub Date: 2026-01-30 DOI: 10.1016/j.eehl.2026.100217
Hualong Zhu , Yongwei Xiong , Zhi Yuan , Yexin Luo , Kongwen Ouyang , Tiantian Wang , Hua Wang , Yufeng Zhang , Wei Chang , Jin Zhang , Hao Li , Lan Gao , Dexiang Xu , Hua Wang
{"title":"Prenatal cadmium exposure and male infertility in mice: A multi-generational mechanistic study","authors":"Hualong Zhu ,&nbsp;Yongwei Xiong ,&nbsp;Zhi Yuan ,&nbsp;Yexin Luo ,&nbsp;Kongwen Ouyang ,&nbsp;Tiantian Wang ,&nbsp;Hua Wang ,&nbsp;Yufeng Zhang ,&nbsp;Wei Chang ,&nbsp;Jin Zhang ,&nbsp;Hao Li ,&nbsp;Lan Gao ,&nbsp;Dexiang Xu ,&nbsp;Hua Wang","doi":"10.1016/j.eehl.2026.100217","DOIUrl":"10.1016/j.eehl.2026.100217","url":null,"abstract":"<div><div>Male infertility affects approximately one in seven couples worldwide. Prenatal cadmium (Cd) exposure has been shown to affect offspring phenotypes and increase susceptibility to diseases later in life. However, the effects of prenatal Cd exposure on multi-generational offspring fertility and the mechanisms remain unknown. A novel murine multi-generational (F1–F3 offspring) male subfertility model induced by prenatal Cd exposure was developed. The levels of testosterone and steroidogenic enzymes were also lower in these offspring’s testes. The ubiquitin-dependent degradation of NR4A1, the upstream transcription factor regulating steroidogenic enzymes, was enhanced across generations upon prenatal Cd exposure. After treatment with MG132, an inhibitor of the ubiquitin-proteasome system, the levels of NR4A1 and steroidogenic enzymes were higher in offspring testes with prenatal Cd exposure. Based on the analysis of the UbiBrowser database and testicular global transcriptome, RAPSN was identified as a novel ubiquitin E3 ligase containing the RING-H2_Rapsyn domain that mediates multi-generational testicular NR4A1 ubiquitination. m<sup>6</sup>A epitranscriptome analysis revealed that prenatal Cd exposure upregulated RAPSN expression in multi-generational offspring testes, and was attributed to a higher level of m<sup>6</sup>A modification of <em>Rapsn</em> mRNA. Furthermore, there was a lower level of YTHDC2, a m<sup>6</sup>A reader, in the multi-generational offspring testes with prenatal Cd exposure. Prenatal and postnatal testicular YTHDC2 overexpression reduced the stability of m<sup>6</sup>A-methylated <em>Rapsn</em> mRNA to downregulate RAPSN expression in F1–F3 testes. Overall, YTHDC2 reduction-mediated increment in m<sup>6</sup>A-methylated <em>Rapsn</em> mRNA contributed to prenatal Cd-enhanced multi-generational susceptibility to male subfertility.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 1","pages":"Article 100217"},"PeriodicalIF":17.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PM2.5 and its chemical components interact with hypoxia to increase the risk of hospitalization for peripheral arterial disease PM2.5及其化学成分与缺氧相互作用,增加外周动脉疾病住院的风险。
IF 17.6
Eco-Environment & Health Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1016/j.eehl.2026.100221
Li He , Ce Liu , Baofeng Zhou , Hao Zhao , Zhaoru Yang , Erkai Zhou , Huan Chen , Huanhuan Wei , Ququmo Guoji , Yuxin He , Bin Luo
{"title":"PM2.5 and its chemical components interact with hypoxia to increase the risk of hospitalization for peripheral arterial disease","authors":"Li He ,&nbsp;Ce Liu ,&nbsp;Baofeng Zhou ,&nbsp;Hao Zhao ,&nbsp;Zhaoru Yang ,&nbsp;Erkai Zhou ,&nbsp;Huan Chen ,&nbsp;Huanhuan Wei ,&nbsp;Ququmo Guoji ,&nbsp;Yuxin He ,&nbsp;Bin Luo","doi":"10.1016/j.eehl.2026.100221","DOIUrl":"10.1016/j.eehl.2026.100221","url":null,"abstract":"<div><div>This study investigated the combined effects of fine particulate matter (PM<sub>2.5</sub>) exposure and ambient oxygen (O<sub>2</sub>) availability on peripheral artery disease (PAD) hospitalizations in Gansu Province, China, from 2018 to 2022 (N = 38,514). A time-series case-crossover design with conditional logistic regression assessed short-term exposure to daily PM<sub>2.5</sub> and its major chemical components (black carbon [BC], organic carbon [OC], sulfate [SO<sub>4</sub><sup>2−</sup>], nitrate [NO<sub>3</sub><sup>−</sup>], ammonium [NH<sub>4</sub><sup>+</sup>], and chloride [Cl<sup>−</sup>]). Atmospheric O<sub>2</sub> levels were estimated based on altitude, temperature, and humidity. Short-term exposure to PM<sub>2.5</sub> was associated with an increased risk of PAD hospitalization, notably at lag 1 (odds ratio [OR] = 1.003; 95% confidence interval [CI]: 1.002–1.004). Carbonaceous pollutants exhibited delayed effects, with peak associations at lag 6 for BC (OR = 1.069; 95% CI: 1.035–1.105) and OC (OR = 1.028; 95% CI: 1.011–1.050), per 1 μg/m<sup>3</sup> increase. Secondary inorganic aerosols showed acute effects at lag 1: Cl<sup>−</sup> (OR = 1.107; 95% CI: 1.063–1.150), NH<sub>4</sub><sup>+</sup> (OR = 1.040; 95% CI: 1.022–1.060), SO<sub>4</sub><sup>2−</sup> (OR = 1.025; 95% CI: 1.015–1.036), and NO<sub>3</sub><sup>−</sup> (OR = 1.030; 95% CI: 1.018–1.042), per 1 μg/m<sup>3</sup> increase. Nonlinear exposure–response curves revealed a stronger PAD risk under lower O<sub>2</sub> conditions (&lt;18%). The PM<sub>2.5</sub>-related risk was amplified in high-altitude residents (&gt;1500 m), older adults (&gt;60 years), females, emergency admissions, and during the cold season. These findings suggest that ambient PM<sub>2.5</sub> and lower O<sub>2</sub> levels interact synergistically to elevate PAD hospitalization risk, emphasizing the urgent need for region-specific air quality controls and targeted health protection strategies.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 1","pages":"Article 100221"},"PeriodicalIF":17.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soil health boundaries for navigating agricultural trade-offs 引导农业权衡的土壤健康边界
IF 17.6
Eco-Environment & Health Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1016/j.eehl.2026.100223
Guoliang Wang, Siwen Cheng, Tian Li, Qixing Zhou
{"title":"Soil health boundaries for navigating agricultural trade-offs","authors":"Guoliang Wang,&nbsp;Siwen Cheng,&nbsp;Tian Li,&nbsp;Qixing Zhou","doi":"10.1016/j.eehl.2026.100223","DOIUrl":"10.1016/j.eehl.2026.100223","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 1","pages":"Article 100223"},"PeriodicalIF":17.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between nocturnal ozone enhancement and daily cardiovascular mortality: A multi-city study in China 夜间臭氧增强与每日心血管死亡率之间的关系:中国多城市研究
IF 17.6
Eco-Environment & Health Pub Date : 2026-03-01 Epub Date: 2025-12-24 DOI: 10.1016/j.eehl.2025.100211
Zhihan Jian , Peng Yin , Renjie Chen , Lijun Wang , Yixiang Zhu , Xia Meng , Haidong Kan , Yue Niu , Maigeng Zhou
{"title":"Association between nocturnal ozone enhancement and daily cardiovascular mortality: A multi-city study in China","authors":"Zhihan Jian ,&nbsp;Peng Yin ,&nbsp;Renjie Chen ,&nbsp;Lijun Wang ,&nbsp;Yixiang Zhu ,&nbsp;Xia Meng ,&nbsp;Haidong Kan ,&nbsp;Yue Niu ,&nbsp;Maigeng Zhou","doi":"10.1016/j.eehl.2025.100211","DOIUrl":"10.1016/j.eehl.2025.100211","url":null,"abstract":"<div><div>The health effects of ambient ozone (O<sub>3</sub>) pollution have been well documented, but most studies have focused on daytime exposure, with limited research on nighttime O<sub>3</sub>. Nocturnal O<sub>3</sub> enhancement (NOE) refers to unexpected increases in nighttime O<sub>3</sub> concentrations over a few hours, yet the health effects of this phenomenon remain unknown. This study evaluated the short-term association between NOE days and cardiovascular mortality by conducting a multi-city time-series analysis in China (2013–2015). Nine definitions were adopted to identify site-level NOE events, considering both average O<sub>3</sub> levels and peak increments at night. A city-level NOE day was defined as a day when over 60% of the monitoring stations within a city recorded at least one site-level NOE event. City-level associations were analyzed using over-dispersed generalized additive models, and national estimates were pooled using meta-analysis. We also conducted stratified analyses by age, sex, season, and region. We found significant associations between NOE days and increased mortality due to total cardiovascular disease (CVD) and coronary heart disease (CHD). Under the strictest NOE definition, mortality risk increased by 1.7% (95% CI: 0.8%, 2.5%) for total CVD and 2.1% (95% CI: 0.9%, 3.3%) for CHD on the day after NOE. Relatively higher risk estimates were found in individuals aged 5–64 years, females, the warm season, and the southern region. No stable associations were found with stroke mortality. These findings offer new insights into the health impacts of NOE and underscore the need for time-phased actions to control both daytime and nighttime O<sub>3</sub> air pollution.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"5 1","pages":"Article 100211"},"PeriodicalIF":17.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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