Eco-Environment & Health最新文献

{"title":"Corrigendum to “A systematic review of the impacts of exposure to micro- and nano-plastics on human tissue accumulation and health” [Eco-Environ. Health (2023)195–207]","authors":"Yudong Feng , Chen Tu , Ruijie Li , Di Wu , Jie Yang , Yankai Xia , Willie J.G.M. Peijnenburg , Yongming Luo","doi":"10.1016/j.eehl.2025.100137","DOIUrl":"10.1016/j.eehl.2025.100137","url":null,"abstract":"","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100137"},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The wheel of time: The environmental dance of aged micro- and nanoplastics and their biological resonance","authors":"Hongjian Li ,&nbsp;Lihua Bai ,&nbsp;Sijia Liang ,&nbsp;Xiru Chen ,&nbsp;Xinyue Gu ,&nbsp;Chao Wang ,&nbsp;Cheng Gu","doi":"10.1016/j.eehl.2025.100138","DOIUrl":"10.1016/j.eehl.2025.100138","url":null,"abstract":"<div><div>The aging of micro- and nanoplastics (MNPs) significantly affects their environmental behavior and ecological impacts in both aquatic and terrestrial ecosystems. This review explored the known effects of aging on MNPs and identified several key perspectives. Firstly, aging can alter the environmental fate and transport of MNPs due to changes in their surface properties. This alteration accelerates their accumulation in specific habitats like oceans and soils, resulting in increased bioaccumulation by organisms. In addition, aged MNPs interact differently with living organisms than their pristine counterparts by influencing the attachment of biofilms and other microorganisms in aquatic ecosystems. Moreover, the aging processes of MNPs exhibit adverse effects on aquatic and terrestrial organisms via increasing the bioavailability and potential toxicity of MNPs as degradation products are released. Last but not least, the biodegradation potential of MNPs can be altered by the aging process, thus affecting their degradation rates and pathways in the environment. However, there are still knowledge gaps regarding the natural aging behaviors of MNPs, such as the aging mechanisms of different types of plastic, the influence of environmental factors, the release of pollutants, and even the effects of aging on their transformation in different ecosystems. Therefore, a great contribution can be made to sustainable plastic use and environmental preservation by studying the natural aging of common MNPs and their subsequent biological effects.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100138"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastics enhance the prevalence of antibiotic resistance genes in mariculture sediments by enriching host bacteria and promoting horizontal gene transfer","authors":"Yifan Liu ,&nbsp;Liuqingqing Liu ,&nbsp;Xiao Wang ,&nbsp;Mengying Shao ,&nbsp;Zihan Wei ,&nbsp;Lina Wang ,&nbsp;Bing Li ,&nbsp;Chenguang Li ,&nbsp;Xianxiang Luo ,&nbsp;Fengmin Li ,&nbsp;Hao Zheng","doi":"10.1016/j.eehl.2025.100136","DOIUrl":"10.1016/j.eehl.2025.100136","url":null,"abstract":"<div><div>Microplastics (MPs) and antibiotic resistance genes (ARGs) pose significant challenges to the One Health framework due to their intricate and multifaceted ecological and environmental impacts. However, the understanding of how MP properties influence ARG prevalence in mariculture sediments remains limited. Herein, the polystyrene (PS) and polyvinyl chloride (PVC) MPs with different sizes (20–120 μm and 0.5–2.0 mm) were selected to evaluate their impacts and underlying mechanisms driving ARGs dissemination. The results showed that PS and PVC MPs increased the relative abundance of ARGs by 1.41–2.50-fold and 2.01–2.84-fold, respectively, compared with control, particularly high-risk genes. The polymer type effect was identified as more influential than the size effect in driving the sediment resistome evolution. PVC shifted the microbial community assembly from stochastic to deterministic processes, thus enriching ARG host pathogens. Furthermore, the highly hydrophobic PS not only recruited the host bacteria colonization but also facilitated ARG exchange within the plastisphere. The exogenous additives released by PVC (e.g., heavy metals, bisphenol A, and tridecyl ester) and the particles synergistically promoted ARG conjugative transfer by inducing oxidative stress and enhancing cell membrane permeability. These findings revealed how MPs characteristics facilitated the spread of ARGs in marine benthic ecosystems, underscoring the importance of mitigating MPs pollution to maintain mariculture ecosystem health, prevent zoonotic diseases, and balance global mariculture with ecological health.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100136"},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143436955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of nanoscale zero-valent iron loaded biochar on the fate of phenanthrene in soil-radish (Raphanus sativus L. var.radculus pers) system","authors":"Lianzhou Shen ,&nbsp;Yue Cai ,&nbsp;Juan Gao","doi":"10.1016/j.eehl.2025.100134","DOIUrl":"10.1016/j.eehl.2025.100134","url":null,"abstract":"<div><div>Nanoscale zero-valent iron loaded on biochar (nZVI@BC) has been proven to be effective in activating persulfate to remediate soil organic pollutants. However, studies on subsequent plant growth and microbial community changes in remediated soil remain limited. In this study, nZVI@BC, nZVI, and nanoscale biochar (nBC) were ball-mill produced and applied as amendments in pot experiments with PAH-contaminated soil to investigate their impacts on soil-crop (radish, <em>Raphanus sativus</em> L.) systems, and the widely distributed phenanthrene (Phe) was selected as model pollutant. The results indicate that nZVI@BC could induce more (75%) Phe accumulation in radish compared to the control treatment, but did not result in significant differences in plant biomass or enzyme activity. In Phe non-contaminated treatments, the Fe content of radish shoots increased from 86.87 ± 5.61 mg/kg DW without material application to 125.20 ± 11.93 mg/kg DW with nZVI@BC, while no significant differences were observed in roots. nZVI@BC and nBC increased the non-desorbed fraction of PAHs with low bio-availability by 13.6% and 10.2%, respectively, after 45 days compared to the control treatment. Illumina MiSeq sequencing revealed that nZVI@BC did not adversely affect the richness and diversity of soil microbial communities. Instead, it promoted the enrichment of bacteria related to the degradation of organic pollutants, such as <em>Lysobacter</em> and <em>Spingomonas</em>. The findings suggest that nZVI@BC after chemical oxidation remediation might be harmful to subsequent plants and ecosystems but much better than nZVI alone. The amount of nZVI@BC should be accurately calculated before chemical oxidation remediation.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100134"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of allele-specific RT-qPCR and genomic sequencing in wastewater-based surveillance of SARS-CoV-2","authors":"Md Pervez Kabir ,&nbsp;Élisabeth Mercier ,&nbsp;Walaa Eid ,&nbsp;Julio Plaza-Diaz ,&nbsp;Patrick M. D'Aoust ,&nbsp;Chrystal Landgraff ,&nbsp;Lawrence Goodridge ,&nbsp;Opeyemi U. Lawal ,&nbsp;Shen Wan ,&nbsp;Nada Hegazy ,&nbsp;Tram Nguyen ,&nbsp;Chandler Wong ,&nbsp;Ocean Thakali ,&nbsp;Lakshmi Pisharody ,&nbsp;Sean Stephenson ,&nbsp;Tyson E. Graber ,&nbsp;Robert Delatolla","doi":"10.1016/j.eehl.2025.100135","DOIUrl":"10.1016/j.eehl.2025.100135","url":null,"abstract":"<div><div>Clinical genomic surveillance is regarded as the gold standard for monitoring SARS-CoV-2 variants globally. However, as the pandemic wanes, reduced testing poses a risk to effectively tracking the trajectory of these variants within populations. Wastewater-based genomic surveillance that estimates variant frequency based on its defining set of alleles derived from clinical genomic surveillance has been successfully implemented. This method has its challenges, and allele-specific (AS) RT-qPCR or RT-dPCR may instead be used as a complementary method for estimating variant prevalence. Demonstrating equivalent performance of these methods is a prerequisite for their continued application in current and future pandemics. Here, we compared single-allele frequency using AS-RT-qPCR, to single-allele or haplotype frequency estimations derived from amplicon-based sequencing to estimate variant prevalence in wastewater during emergent and prevalent periods of Delta, Omicron, and two sub-lineages of Omicron. We found that all three methods of frequency estimation were concordant and contained sufficient information to describe the trajectory of variant prevalence. We further confirmed the accuracy of these methods by quantifying the diagnostic performance through Youden's index. The Youden's index of AS-RT-qPCR was reduced during the low prevalence period of a particular variant while the same allele in sequencing was negatively influenced due to insufficient read depth. Youden's index of haplotype-based calls was negatively influenced when alleles were common between variants. Coupling AS-RT-qPCR with sequencing can overcome the shortcomings of either platform and provide a comprehensive picture to the stakeholders for public health responses.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100135"},"PeriodicalIF":0.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thiamethoxam at environmentally relevant concentrations induces neurotoxicity in zebrafish larvae through binding with multiple receptors","authors":"Xiuwen Li ,&nbsp;Hanbing Zhao ,&nbsp;Minjuan Gong ,&nbsp;Feng Zhang ,&nbsp;Shengnan Liu ,&nbsp;Zepeng Zhang ,&nbsp;Yide He ,&nbsp;Henner Hollert ,&nbsp;Xiaowei Zhang ,&nbsp;Wei Shi ,&nbsp;Qing Zhou ,&nbsp;Aimin Li ,&nbsp;Peng Shi","doi":"10.1016/j.eehl.2024.12.002","DOIUrl":"10.1016/j.eehl.2024.12.002","url":null,"abstract":"<div><div>Thiamethoxam (THM) is one of the most widely used insecticides globally, which was designed to selectively target nicotinic acetylcholine receptors (nAChRs) in the insect nervous system and is generally considered safe for non-targeted organisms. However, increasing evidence has demonstrated its neurotoxicity in aquatic organisms, though the underlying mechanisms, especially at environmentally relevant concentrations, remain largely unclear. In this study, the swimming distance of zebrafish was significantly shortened by 14.06%–21.64% after exposure to THM at 10–1000 ng/L. This behavioral impairment may result from the damage to nervous and visual systems, as confirmed by notable apoptosis, histological analysis of the eyes, and differential expression of numerous genes. Molecular docking and biomarkers assays found that THM can bind with nAChR and multiple hormone receptors, with binding energies varying from −3.75 to −6.74 kcal/mol. Consequently, the concentrations of a neurotransmitter (acetylcholine) and related hormones (cortisol, triiodothyronine, thyroxine, and thyroid-stimulating hormone) were significantly affected. Further investigations using a weighted gene correlation network and metabolomics suggest that THM may enter the cell via endocytosis and bind with multiple hormone receptors, potentially activating the MAPK signaling pathway. This activation may disrupt purine and pyrimidine metabolism in the cell nucleus, ultimately leading to cell apoptosis and neurotoxicity. This study reveals that THM, even at environmentally relevant concentrations, poses neurological risks to zebrafish and underscore the need for urgent attention to the ecological impacts of THM in aquatic environments.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100133"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children-specific environmental protection strategies are needed in China","authors":"Jun Zhang ,&nbsp;Wen Jiang ,&nbsp;Fangbiao Tao ,&nbsp;Guodong Ding ,&nbsp;Fei Li ,&nbsp;Ying Tian ,&nbsp;Shu Tao","doi":"10.1016/j.eehl.2025.01.001","DOIUrl":"10.1016/j.eehl.2025.01.001","url":null,"abstract":"<div><div>China, home to over 250 million children, has witnessed remarkable economic development in recent decades, successfully addressing many issues related to basic hygiene and sanitation in children, thereby altering the childhood disease spectrum. However, the emergence of environment-related disorders among children has become a significant concern. Despite the rapid accumulation of scientific knowledge on the adverse effects of environmental pollution on child health, the availability of children-specific protective strategies and actions remains alarmingly low. This commentary synthesizes the information and viewpoints presented and discussed by experts at the International Forum on Children's Environmental Health in China. It summarizes the strategies and actions proposed to reduce adverse environmental exposure and protect children's short- and long-term health and a call for more children-centered evidence-action transformation. The following four specific actions were proposed: (1) strengthen health education in parents, caregivers, and children, and personal protection for children; (2) monitor child exposure and environment-related health status; (3) set up child-specific interventions and regulations; and (4) conduct more research on environment exposures and child health.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100132"},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced As(III) adsorption-oxidation via synergistic interactions between bacteria and goethite","authors":"Jie Deng ,&nbsp;Shaowei Mi ,&nbsp;Chenchen Qu,&nbsp;Qiaoyun Huang,&nbsp;Xionghan Feng,&nbsp;Xiaoming Wang","doi":"10.1016/j.eehl.2024.12.001","DOIUrl":"10.1016/j.eehl.2024.12.001","url":null,"abstract":"<div><div>The adsorption and oxidation of arsenite [As(III)] by soil components are critical processes that influence its toxicity and mobility. However, the specific mechanisms driving the synergistic interactions among bacteria, soil minerals, and humic acid (HA) in these processes remain insufficiently understood. This study investigated the effects of goethite and HA association on As(III) adsorption-oxidation by the As(III)-oxidizing bacterium SY8 using batch incubation experiments and spectroscopic analyses. The results indicated that goethite inhibited the growth of SY8, but its binary and ternary composites with HA and SY8 substantially enhanced the adsorption and oxidation of As(III) compared to SY8 alone. This enhancement could be attributed to the generation of hydroxyl radicals (·OH) through Fenton-like reactions that contribute to the enhanced oxidation of As(III). The Fenton-like reactions involved interactions between H₂O₂ and goethite, as well as the activation of molecular O₂ by structural Fe(II). Furthermore, the proportion of As(V) associated with the solids was lower than that in the solution, suggesting that As(III) oxidation by SY8 was potentially inhibited by As(III) adsorption on goethite. Additionally, HA did not affect SY8 growth or its As(III) oxidation capability, but slightly enhanced As adsorption on the composites. These findings reveal a complex interplay among microbial, mineral, and organic matter interactions. Understanding these interactions is essential for elucidating soil As biogeochemical processes and developing effective remediation strategies for As-contaminated environments.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the tailpipe: Review of non-exhaust airborne nanoparticles from road vehicles","authors":"Yingyue Wei ,&nbsp;Prashant Kumar","doi":"10.1016/j.eehl.2024.11.003","DOIUrl":"10.1016/j.eehl.2024.11.003","url":null,"abstract":"<div><div>With the electrification of road vehicles leading to a reduction in tailpipe emissions, the relative contribution of non-exhaust emissions (NEEs) has become increasingly prominent. NEEs, particularly nanoparticles smaller than 100 nm in aerodynamic diameter (PM_0.1), present significant health and environmental risks. A comprehensive understanding and strategic management of these emissions are urgently required to mitigate their impact. This article reviews existing studies and reveals that nanoparticles in NEEs are generated from brake and tyre wear under critical temperature conditions, while road wear and resuspension do not directly produce nanoparticles but contribute to larger particles. Common methodologies in studying these emissions include laboratory experiments (with brake dynamometers, tyre dynamometers, chassis dynamometers, and simulators), field tests (tunnel and real road emission tests), and source apportionments. The emission rate of PM_0.1, calculated based on particle number concentration, ranges from 1.2% to 98.9%, depending on driving conditions. Extreme driving conditions result in high nanoparticle generation. Emission inventories reveal that PM_0.1 emission levels have remained stable since 2020, without an observable reduction. Moreover, emissions attributable to brake wear are found to surpass those from tyre wear. Current mitigation strategies focus on material improvements for brake pads and tyres, better road maintenance, and regulatory measures. Mitigating the environmental and health impacts of nanoscale particulate matter requires additional research and regulations to control it at the source.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100130"},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ambient air pollution exposure in relation to cerebral small vessel disease in Chinese population: A cranial magnetic resonance imaging-based study","authors":"Yudiyang Ma ,&nbsp;Ying Hui ,&nbsp;Linxi Tang ,&nbsp;Jianing Wang ,&nbsp;Meiqi Xing ,&nbsp;Lei Zheng ,&nbsp;Feipeng Cui ,&nbsp;Shuohua Chen ,&nbsp;Shouling Wu ,&nbsp;Zhenchang Wang ,&nbsp;Yaohua Tian","doi":"10.1016/j.eehl.2024.10.004","DOIUrl":"10.1016/j.eehl.2024.10.004","url":null,"abstract":"<div><div>Cerebral small vessel disease (CSVD), a chronic and progressive vascular disorder closely associated with stroke and dementia, is primarily identified and diagnosed in cranial magnetic resonance imaging (MRI). Given the limited evidence on the relationship between air pollution and CSVD, this study aimed to investigate the links between multiple air pollutants exposure and CSVD risk. Eligible subjects and their cranial MRI data were obtained from the Multi-modality Medical Imaging Study Based on Kailuan Study, totaling 1216 participants. Ordinal and binary logistic regression models were utilized to evaluate the associations between air pollution exposure and the neuroimaging markers of CSVD. For each interquartile range increase in air pollutant exposure during the examination year, the odds ratios and 95% confidence intervals of the increased white matter hyperintensity burden were 1.45 (1.15, 1.84) for PM_2.5, 1.72 (1.27, 2.34) for PM₁₀, 1.26 (1.05, 1.51) for SO₂, 1.52 (1.16, 2.00) for NO₂, and 1.63 (1.26, 2.13) for CO. The results remained consistent even when the model was fitted using air pollution from different exposure windows. Furthermore, the estimated effect sizes for the total burden of CSVD were 1.20 (1.01, 1.43) for PM_2.5, 1.39 (1.12, 1.74) for PM₁₀, 1.26 (1.03, 1.53) for NO₂, and 1.30 (1.08, 1.58) for CO. These findings suggest that a positive link between air pollutants exposure and neuroimaging markers of CSVD in the Chinese population, revealing the importance of controlling environmental pollutants to protect the population against cerebral small vessel damage.</div></div>","PeriodicalId":29813,"journal":{"name":"Eco-Environment & Health","volume":"4 1","pages":"Article 100129"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}