International Journal of Medical Sciences And Clinical Research最新文献

{"title":"COMPARATIVE CONCLUSIONS OF DIAGNOSIS IN UTERINE BODY CANCER","authors":"I. S. Abdinazarova, N. Atakhanova, N. I. Tursunova","doi":"10.37547/ijmscr/volume03issue04-01","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-01","url":null,"abstract":"Evaluation of the effectiveness and diagnostic accuracy of the Pipelle device in the early stages of endometrial sampling, precancerous diseases, including endometrial hyperplasia, atypical hyperplasia, endometrial polyps, and various histological types of endometrial cancer, compared to the traditional curette.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125997661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF TOXIC COMPLICATIONS OF CHRONOCHEMOTHERAPY IN THE TREATMENT OF MALIGNANT TUMOR DISEASES","authors":"Karimov M.A., Makhmudova R.Y., A. R.A, O'rinboev M.R., Beknazarov A.T., Nurkabilov O.T.","doi":"10.37547/ijmscr/volume03issue04-21","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-21","url":null,"abstract":"the Andijan regional oncology dispensary analyzed the 120 patients on the \"D\" account for the side effects observed after chemotherapy and chronochemotherapy treatments. In 80-90% of patients receiving chemotherapy, different manifestations of side effects are observed. The observation of these toxic complications is explained by the effect of the cytostatic drug on typical cells.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124449496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FETOPLACENTAL INSUFFICIENCY AND OZONE THERAPY","authors":"Todjieva Nigina Iskandarovna","doi":"10.37547/ijmscr/volume03issue04-08","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-08","url":null,"abstract":"Placental insufficiency, as well as its complication intrauterine chronic fetal hypoxia, is one of the important problems of modern perinatology. At the same time, its numbers have been increasing in recent years. Purpose - Evaluation of the effect of ozone therapy on the blood circulation of the mother and fetus, fetoplacental blood flow and the degree of adaptation of the fetus to hypoxia according to the results of cardiotocography, ultrasound and dopplerometry. Material and methods: 38 pregnant women who applied to the Department of Obstetrics and Gynecology of Clinic No. 1 of the Samara State Medical University with fetoplacental insufficiency were divided into two groups according to the type of treatment: patients who received complex treatment with ozone therapy, and patients who received standard medical procedures. Results: about a third of women in each group had a combined extragenital pathology. Women in both groups were statistically comparable when compared in terms of general clinical characteristics, basic anthropometric data, extragenital diseases and reproductive history. The most common complications of childbirth were premature rupture of amniotic fluid (4 in the 1st group - 22.2% and 5-25% in the 2nd group) and acute fetal hypoxia (3-16.7% and 3-15%). Conclusion: Thus, the indicators of maternal-fetal circulation, fetoplacental circulation in women in the ozone therapy group were more positive than in the 2nd group, and the level of fetal adaptability to hypoxia was higher.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121517466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF THE INFLUENCE OF COMPLEX TREATMENTS ON KIDNEY FUNCTIONAL RESERVE IN PATIENTS WITH LIVER CIRRHOSIS DEVELOPED DUE TO HEPATITIS V AND C.","authors":"Abdulazizkhojiev B.R., J. M.A., Ravzatov J.B.","doi":"10.37547/ijmscr/volume03issue04-02","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-02","url":null,"abstract":"Cirrhosis of the liver is manifested by necrosis of hepatocytes, disruption of its normal architecture due to diffuse growth of connective tissue and the formation of regeneration nodules, as well as developing fibrosis. The article presents a modern approach to the treatment of hepatorenal syndrome, one of the severe complications of the disease. The effect of eplerenone, L-ornithine L-aspartate and glutathione drugs on the functional reserve of kidneys was evaluated on the basis of complex treatment.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124678374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE ANALYSIS OF THE CLINICAL EFFICACY OF COMBINED NEUROPROTECTION IN PATIENTS WITH ISCHEMIC STROKE ON THE BACKGROUND OF COVID-19","authors":"M. M. Yuldasheva, E. Majidova","doi":"10.37547/ijmscr/volume03issue04-05","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-05","url":null,"abstract":"This article discusses the comparative analysis of the clinical efficacy of combined neuroprotection in patients with ischemic stroke on the background of COVID-19. To study the effect of the developed measures for drug and non-drug therapy, which included exercises (exercise therapy), patients were observed for the first 3 months of treatment. The second subgroup MG-2 received standard therapy with observation at the same time. Exercise therapy was developed in collaboration with instructors and rehabilitation specialists.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115210314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VARICOSE DISEASE AND PRECNANCY","authors":"Khudoyarova Dildora Rakhimovna, Yusupov Orzimurod Shomurodovich","doi":"10.37547/ijmscr/volume03issue04-07","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-07","url":null,"abstract":"The article presents observational data of patients with varicose veins and analyzes the course of pregnancy. The patients were divided into three groups depending on the type of varicose veins, the control group consisted of healthy pregnant women who developed varicose veins during this pregnancy. The work was carried out on the basis of the Department of Obstetrics and Gynecology No. 1 of the Samarkand State Medical University. The study revealed exacerbation of the phenomena of varicose veins in the second - third trimester of pregnancy, as well as complications of pregnancy compared with the control group.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126327799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE CONSEQUENCES OF POLYHYDRAMNIOS FOR THE MOTHER AND FETUS","authors":"Zakirova Fotima Islamovna, Abdullaeva Nigora Erkinovna, Telmanova Jasmina Farruxovna","doi":"10.37547/ijmscr/volume03issue04-20","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-20","url":null,"abstract":"Polyhydramnios is an obstetric pathology, which is characterized by an increase in the volume of amniotic fluid (amniotic fluid) of more than 1500 ml. The purpose of the study was to study the frequency of causes, the course of pregnancy, the outcome of childbirth and the condition of the newborn with polyhydramnios. To achieve this goal, a retrospective analysis of the history of childbirth of 72 women with polyhydramnios who delivered in the obstetric department of the Samara State Medical University clinic in 2022 was carried out. The course of pregnancy in women with polyhydramnios is complicated by: preeclampsia of the first and second half of pregnancy, miscarriage and premature birth. Perinatal outcomes are characterized by: intrauterine retention syndrome, prematurity, malformations of the central nervous system, cerebrovascular accidents and intrauterine infections.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126715709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TOTAL HYSTERECTOMY IN MODERN MEDICINE","authors":"Negmadjanov Bakhodir Boltayevich, Shavazi Nargiz Nuraliyevna, Ahadova Nigina Jamolovna","doi":"10.37547/ijmscr/volume03issue04-06","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-06","url":null,"abstract":"The article presents the materials of the research work on the basis of the Department of Obstetrics and Gynecology No. 3 in the Department of Obstetrics and Gynecology of the Maternity Complex No. 1 of the city of Samarkand. The data on total hysterectomy in recent years were studied, the indications for hysterectomy and the course of the postoperative period were analyzed. As a result of the study, predictors and risk groups among women were identified depending on the stage and form of the pathological process. The frequent complications of the surgical process and the postoperative period were studied.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"52 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114131280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREDICTION AND STUDY OF THE OCCURRENCE OF CERVICAL CANCER RECURRENCE","authors":"Ortikova Hilola Ubaydullayevna, Esankulova Bustonoy Sobirovna, Musayev Mexroj Bakhtiyorovich","doi":"10.37547/ijmscr/volume03issue04-19","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-19","url":null,"abstract":"Cervical cancer has been found to have increased morbidity and mortality in women around the world. Despite complex treatment according to stratification, the risk of relapse is observed in up to 40% of patients Purpose of the study: - Improving the result of early diagnosis of recurrence of cervical cancer stump after complex treatment, by determining the value of the immune response by immunohistochemical markers in combination with the results of complex research methods Materials and methods: - The basis of the research work was a retrospective analysis of the results of the examination and complex treatment of 87 patients with cervical cancer who were treated and treated at the Republican Specialized Scientific and Practical Center of Oncology and Radiology of Uzbekistan, as well as in its Samarkand Regional Branch from 2012 to 2017. All patients underwent complex treatment of 4 courses of polychemotherapy according to the scheme fluorouracil + cisplatin, laparotomy, extended hysterectomy according to Wertheim type and combined radiation therapy of the small pelvis according to the BOX type. All patients were divided into 2 groups. The first control group consisted of 32 (36.8%) patients with cervical cancer who underwent complex treatment in various sequences, without relapse for three years. The second group included 55 (63.2%) patients with the same diagnosis, but in whom, after complex treatment, an early relapse was detected at the preclinical stage. Results: - In the study of intense infiltrate with lymphoid follicles, it was mainly observed with the degree of tumor differentiation G-3 and G-4, which amounted to 21 (80.7%) patients in the relapse group, while in the control group in 19 (61%) which significantly higher (p≤0.05). In group 1, negative expression was noted in highly and moderately differentiated tumors 9 (29%). With low and undifferentiated tumors, moderate and high expression of VEGF (50%) was noted, with further observation in these patients, locoregional recurrence was noted. In the second group, where there was a relapse of the cervical stump by histological examination, high expression with G-4 was noted in 8 (30.7%), and with G-3 moderate expression in 6 (23%) cases. Low intensity was observed only in 1 (3.8%) G1.As can be seen in Table 4.2, negative expression during relapse, i.e. the absence of lymphoid Conclusions: - Based on our research, differences in cellular immunity play a significant role. In patients without relapses, an increased cellular density of T3DM and T20 was observed, and in patients with relapses and severe course of the disease, low lymphoid density. We should note that in our study, the strongest predictor of prognosis is the number of CD3 + cells per mm 2.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127908494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"USE OF BETASERCA IN PATIENTS WITH HD WITH COCHLEOVESTIBULAR DISORDERS","authors":"U. Khasanov, N.A. Akhunjhanov, G. Khaydarova, K. E. Shaykhova, U. Abdullaev","doi":"10.37547/ijmscr/volume03issue04-09","DOIUrl":"https://doi.org/10.37547/ijmscr/volume03issue04-09","url":null,"abstract":"Betahistine dihydrochloride is a synthetic drug that has the ability to bind to H1 histamine receptors, which are embedded in the neuroreceptor cells of the inner ear. It has a powerful stimulating effect by increasing the release of neurotransmitters (histamine) from the nerve endings of the inner ear receptor cells into the synapse. The neurotransmitter acts on the precapillary sphincters, causing vasodilation of the vessels of the inner ear, increasing their permeability and thereby normalizing intralabyrinthine pressure, i.e. eliminating hydrops.","PeriodicalId":297181,"journal":{"name":"International Journal of Medical Sciences And Clinical Research","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116356010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}