{"title":"PENGARUH KONSENTRASI LARUTAN GULA TERHADAP SEDIAAN SIRUP SELEDRI (APIUM GRAVEOLENS L.)","authors":"Adita Silvia Fitriana","doi":"10.35960/vm.v10i2.440","DOIUrl":"https://doi.org/10.35960/vm.v10i2.440","url":null,"abstract":" \u0000Abstract \u0000 \u0000Celery plants (Apium graveolens L.) have long been used as ingredients of traditional medicine as antihypertensive by the people of Indonesia. This study aims to determine the effect of variations in the addition of celery leaf extract on the manufacture of functional food in the form of syrup from celery leaf extract (Apium graveolens L.) on organoleptic assessment and the quality of syrup preparations. This study used a Completely Randomized Design (CRD) consisting of 5 types of treatment and each treatment was repeated 3 times. Variation of addition of celery leaf extract as follows: (M0) = 0% (control), (M1) = 0.33% (0.55 g), (M2) = 0.39% (0.65 g), (M3 ) = 0.51% (0.85 g) and (M4) = 0.6% (1 g). The results showed that celery leaf extract had antioxidant activity with IC50 values of 98.24 µg / mL and positive (+) containing flavonoids. The addition of celery leaf extract to syrup has a very significant effect on organoleptics (aroma and taste), 7th day pH and viscosity, and all homogeneous syrups. The most preferred treatment panelist was treatment M1 (0.33%) with a scoring score of 4.03 (likes) and a taste of 3.93 (likes) and according to SNI. While the panelists preferred the treatment of M4 (0.6%) with a scoring score of 3.24 (rather like) and flavor of 2.87 (rather like) but according to SNI. The fewer additions of celery leaf extract, the syrup is increasingly preferred by panelists. \u0000 \u0000Keywords: celery, formulation, syrup","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121202201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STUDI PENGARUH UMUR DAN JENIS KELAMIN PADA PASIEN TUBERKULOSIS DI RUMAH SAKIT DKT PURWOKERTO","authors":"Peppy Octaviani","doi":"10.35960/vm.v10i2.437","DOIUrl":"https://doi.org/10.35960/vm.v10i2.437","url":null,"abstract":"ABSTRACT \u0000Pulmonary tuberculosis (TB) is a contagious pulmonary infectious disease that is still a health problem in the world, especially developing countries. Tuberculosis has been proclaimed by WHO (World Health Organization) as Global Emergency since 1992. The purpose of this study is to find out what physical characteristics are at risk of tuberculosis in DKT Hospital Purwokerto. The research design used in this study was a descriptive study with a cross-sectional approach to determine the characteristics of pulmonary TB patients who were adherent to treatment and those who did not comply with treatment at the DKT Hospital in Purwokerto. This research was conducted at the DKT Purwokerto Hospital in May 2018. The samples studied in this study were pulmonary TB patients who were obedient to treatment and non-compliance with treatment at the DKT Purwokerto Hospital for the period of 1 January - 30 December 2017 that met the sample criteria. The results of the study have no relationship between age and the results of sputum examination at the Purwokerto DKT Hospital (p value = 0.286), there is no relationship between sex with the results of sputum examination at DKT Purwokerto Hospital (p value = 0.261). \u0000 \u0000Keywords: Pulmonary TBC, Characteristics, Phlegm Examination \u0000 ","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127524203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Formulasi dan uji stabilitas sediaan lulur dari rimpang kunyit (Curcuma longa linn)","authors":"Rani Prabandari","doi":"10.35960/vm.v10i2.435","DOIUrl":"https://doi.org/10.35960/vm.v10i2.435","url":null,"abstract":"ABSTRACT \u0000Lulur is a type of cosmetics made from flowers and other plant ingredients that are very useful for maintaining beauty, health, smoothness and brightness of the skin of the body. Lulur can help clean the dirt that sticks to the skin due to the influence of weather and pollution factors so that the skin becomes healthy, clean and beautiful. The contents of the substance include turmeric: curcuminoid which consists of curcumin, desmetoksikumin and bisdesmetoksikurkumin and other beneficial substances, such as volatile essential oils of oil, fat, carbohydrates, protein, starch, vitamin C, iron, phosphorus, and calcium. Curcumin is a yellow substance contained by turmeric, on average 10.29%, has broad spectrum biological activity including antihepototoxic, antibacterial and antioxidant so that turmeric is able to be used for traditional medicine both to maintain health and skin beauty of the body, The method used is study experimental scrubs and tested the stability of scrubs containing turmeric rhizome powder. The best scrubs are formula 1 which uses the ratio of turmeric powder to light brown scrub, homogeneous and perfectly fused body scrub, has a pH of 5, spread of 10,321 cm2, has a viscosity consistency of 99,000 mPa.s and adhesion for 4 seconds. \u0000 \u0000Keywords: formulations, scrubs, turmeric. \u0000 \u0000 ","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116208496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perbandingan randemen minyak atsiri sereh (cymbopogon citratus) yang umur panennya 6 bulan Dan 9 bulan dengan metode destilasi air)","authors":"Rani Prabandari","doi":"10.35960/vm.v10i3.430","DOIUrl":"https://doi.org/10.35960/vm.v10i3.430","url":null,"abstract":"AbstractIndonesian nature is very rich in plants containing essential oils. Essential oils can be produced from various parts of plants such as roots, stems, leaves, flowers, or fruit. There are 50-200 species of essential oil producing plants. In Indonesia there are around 40 types of essential oils producing plants. One of the essential oils producing plants is lemongrass (Taufiq, Tuhana, 2008 p: 2). This study aims to determine the comparison of essential oils in Lemongrass (Cymbopogon citratus) which are harvested at 6 months and 9 months with a water distillation method. The procedure for selecting samples and research samples, directly with the object of research, is the citronella plant whose harvest age is 6 months taken from 1 clump and 9 months taken from 1 clump. The results of this study indicate that lemongrass plants with a harvest age of 6 months produce more essential oils compared to lemongrass plants with a harvest age of 9 months. This is influenced by several factors, including climate, harvest age. Lemongrass plants aged 6 months are the optimal age to be harvested, so that they get a higher yield of essential oils, besides that the factors of soil fertility and the intensity of sunlight also affect the content of essential oils of lemongrass.From the results of the research that has been done on the test sample, it can be concluded that the results of the essential oil ration on citronella (Cymbopogon citratus), which has 6 months of harvest age, obtained an average yield of 0.46% v / b and 9 months. 0.35% v / b with the results of the t-test obtained by the price t-count (2.984)> t-table (2.776). So that H0 is rejected and Ha is accepted and it can be concluded that there is a significant difference between lemongrass with 6 months and 9 months of harvest. Keywords: lemongrass, essential oil, age of harvest, water distillation","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116721251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PENGARUH FAKTOR USIA, JENIS KELAMIN, DAN PENGETAHUAN TERHADAP SWAMEDIKASI OBAT","authors":"Hilda Suherman","doi":"10.35960/vm.v10i2.449","DOIUrl":"https://doi.org/10.35960/vm.v10i2.449","url":null,"abstract":"Abstract \u0000 \u0000Self-medication is a human effort to treat diseases or symptoms of minor ailments such as fever, cough, flu, pain and others without a doctor's prescription. In practice, limited knowledge of drugs and their use can be a source of medication errors (medication error). This research was conducted with a cross sectional descriptive research method. Data was collected through a validated questionnaire filling technique. A total of 300 respondents involved in this study were selected by consecutive sampling method from 3 pharmacies in the city of Purwokerto which were determined proportionally according to the population of each pharmacy. Data were analyzed by Chi-square test and Fisher's test used Statistical Product and Servicer Solution (SPSS) version 17. The results showed that the patient's knowledge level was 22.6% classified as poor, 48% classified as moderate, and 29.4% classified as good. The use of self-medication is 26.3% irrational and 73.7% rational. Based on the results of the Chi-square and Fisher test, the level of knowledge is influenced by age, recent education, and occupation. While self-medication rationality is not influenced by gender, education and employment. Based on the results of the study, it was found that the patient's level of knowledge was classified as moderate with a percentage of 48%. While self-administered rationality is classified as rational with a percentage of 73.7%. \u0000 \u0000Keywords: self-medication, pharmacy, rationality of drug use","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114479677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FORMULASI SEDIAAN MASKER ANTIOKSIDAN DARI EKSTRAK TEH HIJAU (CAMELLIA SINENSIS)","authors":"Desi Nawangsari","doi":"10.35960/vm.v10i2.451","DOIUrl":"https://doi.org/10.35960/vm.v10i2.451","url":null,"abstract":"Abstract \u0000 \u0000Research has been carried out on the formulation of maskantioxidant preparations containing green tea leaf extract. The study begins with testing the antioxidant activity of ethanol extract of green tea leaves with a free radical reduction method of 1,1-diphenyl-2-picrylhydrazyl using visible spectrophotometry. Testing of antioxidant activity showed that the ethanol extract of green tea leaves gave an IC50 value of 3.17µg / mL. Formulations of gel masks made were F0 (base without active substances), F1 (base + concentration of ethanol extract of green tea leaves for IC50 (0,000317%)), F2 (base + concentration of ethanol extract of green tea leaves for 50xIC50 (0, 0158%)), F3 (base + concentration of ethanol extract of green tea leaves for 100xIC50 (0.0317%)), F4 (base + concentration of ethanol extract of green tea leaves for IC50), F5 (base + concentration of ethanol extract of green tea leaves worth IC50), F6 (base + concentration of ethanol extract of green tea leaves for IC50. Evaluation of gel mask preparations include, organoleptic examination and homogeneity, \u0000pH, viscosity, dry time of preparation and testing of antioxidant stability. F2 provides better and higher free radical reduction activity than products on the market. F4, F5, F6 shows an increase in free radical reduction activity. \u0000 \u0000Keywords: Green tea leaves (Camellia sinensis L.), DPPh, IC50 gel mask.","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"252 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122494439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PENETAPAN KADAR FLAVANOID TOTAL EKSTRAK DAUN MELINJO (GENATUM GENANOM L.) DENGAN ANALISIS SPEKTROFOTOMETRI UV-VIS","authors":"Putriana Rahmawati","doi":"10.35960/vm.v10i3.445","DOIUrl":"https://doi.org/10.35960/vm.v10i3.445","url":null,"abstract":"Abstract \u0000 \u0000Melinjo plants are an abundant food commodity in Indonesia and have many benefits for consumption ranging from young leaves, flowers, seeds, to the skin. According to Voondan Kueh (1999) all foods derived from melinjo plants have a high nutritional component, such as carbohydrates at 6.60%, protein at 4.20%, calcium at 94.00 mg, vitamins C1, 500 mg and others. The method of this research is Uv-Vis spectrophotometry analysis performed on melinjo leaf samples by measuring the standard absorbance of quercetin flavonoids at a wavelength of 424 nm. The results showed that the content of melinjo leaf flavonoids (Gnetum gnemon L) in Rempoah village was higher than the content of melinjo leaf flavonoids (Gnetum gnemon L) in Dukuh Waluh Village. Rempoah village has a solid soil texture, which causes the roots to easily absorb water from the soil because the particles of soil can hold back the rate of water so that the roots of plants easily absorb water, as a result the plant growth is also getting better. Shown with the content of flavonoid pigments that are better than Dukuh Waluh Village. Whereas in the Dukuh Waluh area the sandy and gravel soil structure results in very weak water binding capacity because the soil particles are too tenuous as a result of lack of water supply so that plant growth is also not good, so there is less flavonoid content. Solid soil causes the roots to easily handle mineral salts and results in increased secondary metabolite content. \u0000 \u0000Keywords: mlinjo, determination, flavanoids","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123544243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PENGARUH PENGGUNAAN VARIASI KONSENTRASI AVICEL PH-101 PADA FORMULA TABLET PREDNISOLONE","authors":"Hilda Suherman","doi":"10.35960/vm.v10i3.446","DOIUrl":"https://doi.org/10.35960/vm.v10i3.446","url":null,"abstract":"Abstract \u0000 \u0000Prednisolone is a steroid class drug that is used to treat certain types of allergies, inflammatory conditions, autoimmune disorders and cancer. Solubility of prednisolone is very difficult to dissolve in water causing problems in the absorption process so that the optimum formula is needed to form Prednisolone tablets that meet the requirements of the physical properties of tablets. The purpose of this study was to make the optimum formula with a combination of lactose excipients, avicel pH-101, and amprotab to obtain prednisolone tablets with good physical properties and dissolution. \u0000Prednisolone tablets made 7 formulas with a combination of lactose (A) Avicel PH-101 (B), and Amprotab (C), Formula I (100% A); Formula II (100% B); Formula III (100% C); Formula IV (50% A + 50% B); Formula V (50% A + 50% C); Formula VI (50% B + 50% C); Formula VII (33.33% A + 33.33% B + 33.33% C) in 2 batches. The method of making prednisolone tablets by direct printing. Testing of prednisolone tablets included the physical properties of tablets, weight uniformity, uniformity in size, hardness, friability, disintegration time, and dissolution test, and content determination. \u0000 \u0000Keywords: optimization of formulas, tablets, Prednisolone, Simplex Lattice Design. \u0000 \u0000 \u0000 ","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132062161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PENGARUH USIA DAN JENIS KELAMIN PADA KEPATUHAN PASIEN DIABETES MELITUS MENGGUNAKAN OBAT ANTIDIABETES DI PERUM KETAPANG SOKARAJA KULON","authors":"Ikhwan Yuda Kusuma","doi":"10.35960/vm.v10i2.443","DOIUrl":"https://doi.org/10.35960/vm.v10i2.443","url":null,"abstract":"ABSTRACT \u0000The WHO survey results show that the number of DM patients in Indonesia is ranked the 4th largest in the world. DM causes death by 5% every year. Deaths from DM are expected to increase by 50% in the next ten years. The results of the 2007 Central Java RISKESDAS showed that the prevalence of DM in Central Java province was 0.8% and overall was 1.3%. The highest prevalence is found in Cilacap Regency (3.9%), second place is Tegal City Regency (3.1%), for the third place is Surakarta (2.8%), fourth place is Pemalang (2.1%), and fifth place is occupied by Banyumas (1.9%) (Ministry of Health, 2009). This study used an experimental design by treating the group of cases. The research instruments in this study were interview guides about the number of remaining antidiabetic drugs to check the compliance and MMAS questionnaires that had been validated and translated into Indonesian versions (Setyaningsih, 2013). The results of data analysis using the Chi-Square test were obtained p = 0.220 (p> 0.05) based on the MMAS questionnaire, this indicates that this indicates that this study of age has a significant influence on the adherence of antidiabetic use in DM patients in Perum Ketapang Sokaraja Kulon. \u0000 \u0000Keywords: Age, Diabetes Mellitus, Drug Information \u0000 \u0000 \u0000 \u0000 \u0000 ","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123869745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FORMULASI DAN EVALUASI SEDIAAN SIRUP DAUN SEREH (Cymbopogon citratus)","authors":"Dina Febrina","doi":"10.35960/vm.v10i2.455","DOIUrl":"https://doi.org/10.35960/vm.v10i2.455","url":null,"abstract":" \u0000ABSTRACT \u0000Lemongrass (Cymbopogon citratus) is one of the plants commonly used as spices by the people of Indonesia. However, the use of lemongrass as cooking spices is only located on the stem, while the lemongrass leaves are still a waste. Even though lemongrass leaves are known to contain phenol active compounds which can act as antioxidants. Lemongrass syrup formulations are made into 3 formulas, Formula I 0,75: 0,25; Formula II 0,25: 0,75; Formula III 0,5: 0,5 for sucrose: Na CMC. Formulation I with sucrose levels: Na CMC (0,75: 0,25) has the most desirable taste and for evaluation has the best value. \u0000 \u0000 \u0000 ","PeriodicalId":288987,"journal":{"name":"Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116565636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}