2011 International Symposium on Micro-NanoMechatronics and Human Science最新文献_第10页

Nano-gyroscope assembly using Carbon Nanotube based on nanorobotic manipulation 基于纳米机器人操作的碳纳米管纳米陀螺仪组装

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102199

Zhan Yang, M. Nakajima, Yajing Shen, T. Fukuda

引用次数: 11

Size-dependent sorting of corneal limbal epithelial cell with microfluidic chip 微流控芯片在角膜缘上皮细胞大小依赖性分选中的应用

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102163

Akiyuki Hasegawa, M. Yamada, M. Seki, M. Yamato, T. Okano

引用次数: 0

Development of sputtering conditions for PZT micro actuator with high piezoelectric property by Au-Pt buffer layer 利用Au-Pt缓冲层制备高压电性能PZT微致动器溅射条件的研究

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102194

R. Takita, K. Tsuchiya, Y. Uetsuji

引用次数: 3

Missing value imputation method using Bayesian network for decision-making on HCR 基于贝叶斯网络的HCR决策缺失值估算方法

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102213

Yoshihiro Miyakoshi, Shohei Kato

{"title":"Missing value imputation method using Bayesian network for decision-making on HCR","authors":"Yoshihiro Miyakoshi, Shohei Kato","doi":"10.1109/MHS.2011.6102213","DOIUrl":"https://doi.org/10.1109/MHS.2011.6102213","url":null,"abstract":"Recently, varied types of robots have been developed in the field of human centered robotics. Human centered robots need to autonomously make their own decisions to live together with human. Accordingly, data mining, especially classification, has been drawing much attention as a component technology to develop decision-making systems. In the real-world data mining, missing value problem is happened, for example, speech containing noise, facial occlusion, and so on. In previous studies, various imputation methods have been developed. Previous imputation methods were developed to solve the missing value problem with lots of explanatory variable, even if some explanatory variables are ineffective for imputation. It has been said that using lots of variable deteriorates in learning efficiency, thus we believe that imputation methods should be developed considering relations among explanatory variables. Therefore we propose the imputation method using Bayesian network. Through the experiments, we can confirmed that proposed method imputes missing values with approximate values, and a classification system successfully classify the test sample, in which missing values are imputed by proposed method, in comparison with some conventional methods.","PeriodicalId":286457,"journal":{"name":"2011 International Symposium on Micro-NanoMechatronics and Human Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122362021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Selective nano-injection using nano-probe based on Nanomanipulation under hybrid microscope 混合显微镜下基于纳米操作的纳米探针选择性纳米注射

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102181

T. Hirano, M. Nakajima, M. Kojima, N. Hisamoto, M. Homma, T. Fukuda

{"title":"Selective nano-injection using nano-probe based on Nanomanipulation under hybrid microscope","authors":"T. Hirano, M. Nakajima, M. Kojima, N. Hisamoto, M. Homma, T. Fukuda","doi":"10.1109/MHS.2011.6102181","DOIUrl":"https://doi.org/10.1109/MHS.2011.6102181","url":null,"abstract":"This paper presents a novel selective nano-injection method by fluorescent nanoprobe insertion based on Nanomanipulation under hybrid microscope. The hybrid microscope is designed to combine the optical microscope (OM) and environmental-scanning electron microscope (E-SEM) to realize biological specimen analysis by optical imaging including fluorescent imaging, and nano-scale manipulation by E-SEM imaging. Based on the bio-nano manipulation system, we propose a nano-injection method by fluorescent nanoprobe insertion. The fluorescent nanoprobe is needed to observe nanoprobe by OM. The nanoprobe is designed to have a sharp tip to insert the probe into biological specimen. It is fabricated by focused ion beam (FIB) process. The nano-scale size is important for minimal damage to biological specimen. The Caenorhabditis elegans (C. elegans) is used as a target biological specimen, which is one of the important model organism for diseases analysis. The nanoinjection technique is needed to transport fluorescent materials or specific biological organism into specific cell for in-vivo experiment. The proposed system is considered to be important as future nano-surgery system for life innovation using model organism.","PeriodicalId":286457,"journal":{"name":"2011 International Symposium on Micro-NanoMechatronics and Human Science","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116352943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Development of the measurement system of upper abdominal palpation 上腹部触诊测量系统的研制

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102242

Takashi Kato, L. Cheng, J. Ito, K. Ikuta

{"title":"Development of the measurement system of upper abdominal palpation","authors":"Takashi Kato, L. Cheng, J. Ito, K. Ikuta","doi":"10.1109/MHS.2011.6102242","DOIUrl":"https://doi.org/10.1109/MHS.2011.6102242","url":null,"abstract":"In the field of the health maintenance, oriental medicine is one of many selective solutions aiming at “prevention” of diseases. It is considered as alternative medicine so far, but some acupuncture treatments have been developed to be effective treatment methods through the regulation of bowels (ROB) for maintaining healthy bodily functions. Along with the development of the treatment methodology, the palpation technique on the upper abdomen has been developed to confirm the movements of digestive tract. Our research project started by evaluating the ROB treatment objectively, investigating the relationship between the effectiveness of ROB treatment and the suppleness of the upper abdomen. A practitioner investigates the reactive force at some trigger points with the palpating finger pressed down until the firm hardness is felt. In this study, the measurement system was thus newly developed to quantify this method. The sensor unit consists a single axis load cell, a magnetic position sensor, and the resin housing to fit a palpating finger. The data acquisition of a male subject was then performed for 6 days trial within 2 months. Data tendencies of abdominal palpation was discussed, and the results of the palpation on the 3 abdominal points show that the relation between the maximum pressing position and the reactive force of abdominal wall represents the proportional relation without the viscosity effect. It is just through the perception of hardness that enables practitioners to diagnose subjectively using abdominal palpation, yet it becomes an effective index for individuals to understand healthy level of the digestive organ objectively, as needed for individual preventive healthcare.","PeriodicalId":286457,"journal":{"name":"2011 International Symposium on Micro-NanoMechatronics and Human Science","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116611316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of bacteria behavior in micro-channel for bacteria driven liposome 细菌驱动脂质体微通道中细菌行为的评价

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102229

M. Kojima, Zhiqin Wang, Tatsuya Miyamoto, M. Nakajima, M. Homma, T. Fukuda

{"title":"Evaluation of bacteria behavior in micro-channel for bacteria driven liposome","authors":"M. Kojima, Zhiqin Wang, Tatsuya Miyamoto, M. Nakajima, M. Homma, T. Fukuda","doi":"10.1109/MHS.2011.6102229","DOIUrl":"https://doi.org/10.1109/MHS.2011.6102229","url":null,"abstract":"Toward to realizing establishment of new micro robot for micro-nano surgery, drag delivery etc., many people proposed microbe as actuator. So, evaluation of microbe property for these application arias is important. From this viewpoint, we try to fabricate evaluation tool for bacterial behavior in micro channel like capillary vessel. This evaluation will be helpful to our recent study “bacteria driven liposome as drag delivery systems”. For this purpose, we fabricated line patterned channel on polydimethylsiloxane (PDMS) chip and junction of three channel on PDMS chip by nano imprinting and rapid prototyping technique respectively. And then some kind of marine bacterial cells (Vibrio alginolyticus), this bacteria can swim in water, are injected into the fabricated micro channel and observed their behavior. As first step, we observed relationship between channel width and swimming behavior and speed in line patterned micro chip, and we found that 1!m channel limited cell behavior as one-dimensional motion. Second step, we evaluate chemotaxis property of bacteria in junction of three channels.","PeriodicalId":286457,"journal":{"name":"2011 International Symposium on Micro-NanoMechatronics and Human Science","volume":"204 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132503085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Establishment of pain evaluation test on the expression of Substance P during injection 建立注射过程中P物质表达的疼痛评价试验

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102152

Mohd Yusri, K. Tsuchiya, K. Kajiwara, M. Kimura

{"title":"Establishment of pain evaluation test on the expression of Substance P during injection","authors":"Mohd Yusri, K. Tsuchiya, K. Kajiwara, M. Kimura","doi":"10.1109/MHS.2011.6102152","DOIUrl":"https://doi.org/10.1109/MHS.2011.6102152","url":null,"abstract":"A microneedle with a size of a female mosquito's labium which can collects blood almost painlessly is effective to reduce pain during the injection. However, the decreasing of the outer diameter will affect inner diameter, rigidity and pressure in inner tube. By decreasing the size of outer diameter, the inner diameter and the rigidity of the needle will decrease while pressure loss will increase. Therefore, we need a pain evaluation test to determine the marginal region of painless for outer diameter size of microneedle in order to design painless microneedle which fulfilled painless, high-rigid and low-pressure loss. Here, a pain evaluation test through stress assessment test has been proposed. However, this pain evaluation test is not a direct method to evaluate pain since the evaluation is conducted through stress. In this study, we focused on the expression of Substance P (SP), which is one of a pain transmitter. The SP has been proven expressed only at the stimulated region after simulated mouse skin with both chemical stimulus and physical stimulus. Therefore, we conducted an experiment by injecting mouse skin with various diameter sizes of needle and determine the best diameter size by measuring the quantity of expressed SP by using image processing.","PeriodicalId":286457,"journal":{"name":"2011 International Symposium on Micro-NanoMechatronics and Human Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131257841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A chip-based system for cell manipulation and cellular function analysis 一个基于芯片的系统，用于细胞操作和细胞功能分析

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102249

T. Shibata, M. Nagai, T. Kawashima

{"title":"A chip-based system for cell manipulation and cellular function analysis","authors":"T. Shibata, M. Nagai, T. Kawashima","doi":"10.1109/MHS.2011.6102249","DOIUrl":"https://doi.org/10.1109/MHS.2011.6102249","url":null,"abstract":"A thorough understanding of cellular functions is a prerequisite for realizing biological applications such as medical diagnostics, drug discovery, and tissue engineering. Therefore, we have been developing novel MEMS devices for massively parallel manipulation and analysis of single cells. They include (1) an array of out-of-plane, hollow SiO2 microneedles capable of introducing desired biomolecules (DNA, proteins, etc.) into living cells and extracting biomolecules expressed in the cells, (2) a micromanipulator array capable of massively parallel trapping and manipulation of single living cells for 2 D/3 D cell patterning applicable to in vitro patterned cell culture, and (3) a cell culture microdevice actuated by piezoelectric thin film for on-chip regulation of cell functions. Furthermore, we have been developing a newly designed probe for atomic force microscope (AFM) , named bioprobe, which is integrated with a sharp-tipped, hollow SiO2 nanoneedle (Fig.1) for analyzing cellular functions in a single living cell with high spatial and temporal resolution; it can be used to perform AFM measurements at the molecular level under near-physiological conditions but also to deliver biomolecules into living cells and to extract target biomolecules in the cells. The MEMS devices proposed here will be powerful tools for addressing fundamental issues in cell biology, neurobiology, pharmacology, and tissue engineering.","PeriodicalId":286457,"journal":{"name":"2011 International Symposium on Micro-NanoMechatronics and Human Science","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125754045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Bipedal gait like motions of a thin viscoelastic object 两足的步态像一个薄的粘弹性物体的运动

2011 International Symposium on Micro-NanoMechatronics and Human Science Pub Date : 2011-12-15 DOI: 10.1109/MHS.2011.6102246

I. Ramirez-Alpizar, M. Higashimori, M. Kaneko

引用次数: 0