The Internet Journal of Pulmonary Medicine最新文献

{"title":"A Rare Case Of Kimura’s Disease Presenting With Cough, Hemoptysis And Axillary Lymph Node Enlargement.","authors":"Salil R. Rajayer, Vishak Acharya, A. Rau, C. Sivaramakrishnan, R. Sahoo, F. Lobo","doi":"10.5580/133e","DOIUrl":"https://doi.org/10.5580/133e","url":null,"abstract":"Kimura’s Disease is a benign, slow growing chronic inflammatory swelling with a predilection for the head and neck regions and has hence been restricted exclusively to literature published in those specialties. Here, we report a unique and interesting case of a 50 year old male who presented with cough, massive hemoptysis and significantly enlarged firm, non tender, mobile axillary nodes. An excision biopsy showed eosinophillic micro abscesses and associated features that gave a diagnosis of Kimura’s. The serum IgE levels and eosinophil counts were high, which corroborated the histopathology. He was treated with oral steroid therapy with the subsidence of symptoms and regression of histopathological parameters within two weeks. This case is highlighted to bring to attention an extremely uncommon presentation of a disease which normally presents in a very different manner although the complex of symptoms is very common in the context of respiratory disease.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"194 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123656094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home Nebulisers – a serious complication","authors":"O. Spencer, C. Blakeley, F. Wrigley","doi":"10.5580/1604","DOIUrl":"https://doi.org/10.5580/1604","url":null,"abstract":"This case report highlights a serious complication after using a home nebuliser machine. An elderly patient, known to have COPD, was brought to the Emergency Department with severe difficulty in breathing. Despite salbutamol nebulisers, his condition did not improve. Reassessment of his airway revealed a nebuliser mouthpiece in his oropharynx which was removed with McGill’s forceps. The patient’s condition immediately improved and he was able to start talking. There are reports of aspiration incidents in the literature after the use of metered dose inhalers, we have not been able to find any other reported incidence of this happening with a home nebuliser machine. Although this event was extremely unusual it highlights when patients are using medical equipment at home unsupervised, they must be educated to be able to use it safely Work carried out at Mayday University Hospital","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"-1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116744542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aquatic to pulmonary: Severe melioidosis following near-drowning from Southern India","authors":"C. Mukhopadhyay, K. Vandana, S. Krishna, K. Saravu, B. Shastri","doi":"10.5580/dcc","DOIUrl":"https://doi.org/10.5580/dcc","url":null,"abstract":"Melioidosis is a known emerging infectious disease in India. Pulmonary melioidosis presents as acute fulminant septecemia, subacute illness, chronic infection, or subclinical disease. Aspiration of water containing bacteria is an unique mode of transmission, which can give rise to pulmonary melioidosis with or without septicaemia. The two unique presentations of pulmonary melioidosis in non-diabetic patients were documented following fresh water drowning and aspiration of water. They had different clinical and radiological presentation, course of illness, and outcome, although the source of infection was similar. One of the patient succumbed to septecemic shock while the other survived with the adequate treatment. Melioidosis was never the differential diagnosis in both the cases. It shows the urgency of the disease to be highlighted in this part of the world, especially among the clinicians and microbiologists, so every similar episode of drowningmight be complimented by the work up of melioidosis and managed as critical.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130174185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence Of Smoking And Physical Activity On Pulmonary Function","authors":"Agron M. Rexhepi, B. Brestovci","doi":"10.5580/1661","DOIUrl":"https://doi.org/10.5580/1661","url":null,"abstract":"The purpose of this study was to examine the influence of smoking and physical activity on lung function. There were used the research method of three groups: smokers, non-smokers and sportsmen. Nine spirometric variables were used to evaluate the pulmonary function and differences between groups. Significance of the differences was tested by ANOVA and Canonical Discriminant Analyses. Sportsmen had significantly higher values of forced expiratory volume in 1 second and expiratory vital capacity, whereas the smokers lower. Non-smokers and sportsmen had similar lung capacity, but better than smokers. Factor Analyses had revealed two latent factors. The first factor explained 64.9% of the total variance and inform about lung capacity. The second factor explained 12.96% of the total variance and inform about air-flowing during respiration. The differences between groups in latent structure were significant. This investigation revealed the effects of smoking and physical activity on decreasing, respectively increasing of respiratory abilities.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128688454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gefitinib as monotherapy in the first-line setting in Non-small cell lung Cancer","authors":"Roshnee Gopall, C. Hong, S. Yi","doi":"10.5580/26bd","DOIUrl":"https://doi.org/10.5580/26bd","url":null,"abstract":"Recent advances in cancer therapy have resulted in the development ofdrugs that target mechanisms involved in neoplastic change and angiogenesis. Oneexample is Gefitinib (‘Iressa’, ZD1839), an orally-active epidermal growth factorreceptor tyrosine kinase inhibitor (EGFR-TKI) that blocks EGFR signaling,thereby inhibiting the growth, proliferation and survival of many solid tumors. This review discusses the potential of Gefitinib as monotherapy in the first line treatment of non-small cell lung cancer (NSCLC). Gefitinib showed promising results as a single agent in NSCLC in terms of tolerability profile and better disease response. Furthermore, it has been demonstrated that a molecularly defined population will benefit most from first-line treatment with Gefitinib.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124716301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstructive Sleep Apnea in a Child with Aicardi Syndrome","authors":"N. Kurugundla, A. Amchentsev, R. Sinha, Schubert Romaine, Gerard Lombardo","doi":"10.5580/4fe","DOIUrl":"https://doi.org/10.5580/4fe","url":null,"abstract":"We report the first known case of Obstructive Sleep Apnea (OSA) in a five-year-old girl with Aicardi syndrome and severe developmental delay, hypotonia, and agenesis of corpus collosum. This case report emphasizes the importance of identifying sleep disordered breathing in all patients with hypotonia and developmental delay, regardless of etiology and level of functioning. The goal of treatment is a potential positive impact on the sleep and wake time quality of life.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116540491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRELIMINARY EXPERIENCE OF THE CLINICAL AND TOMOGRAPHIC CHARACTERISTICS OF PATIENTS WITH NON-REFRACTORY ACUTE RESPIRATORY INSUFFICIENCY CAUSED BY H1N1 INFLUENZA A VIRUS INFECTION AND INTERVENTION OF DISEASE.","authors":"K. B. Claudett, A. Prudente, J. Salvatierra, Flavio Caamacho Olaya, Michelle Grunauer Andrade, P. Holguín","doi":"10.5580/13d2","DOIUrl":"https://doi.org/10.5580/13d2","url":null,"abstract":"IntroductionThe HIN1 Influenza A virus infection has a rapid spread worldwide, and although it is believed to have a low mortality rate, one the virus reaches the acute refractory respiratory insufficiency phase, the mortality rate increases drastically. Materials and MethodsIn this study we report the results of 10 clinical case studies of patients who arrived at the emergency room of the Military Hospital located in Guayaquil, Ecuador during the months of July 22, 2009 through September 11, 2009. Upon arrival the patients presented signs and symptoms of acute respiratory insufficiency and were positive for the H1N1 Influenza A virus. The data presented in this paper emphasises the clinical manifestations, arterial blood gas analysis and high resolution computerized tomography (HRCT) findings. computerized tomography findings (HRCT). Result: The characteristics of the patients studied were the following: Mean age of 28.5 +/15.4 SD. The mean time of patient hospitalization was 12.5 days +/10.9 SD. The mean values of Interleukin 6 were: 17,8 +/9.9 SD. The mean level of SaO2% was 91.3 +/2.5 SD. The mean values for respiratory rate were 28.8 +/-4.2 SD. The mean level of arterial pH was 7.35 +/0.06 SD. The mean values of arterial PCO2 were 40.75 +/7.99 SD. The mean values of arterial PO2 were 59.99 +/9.36 and the mean values of arterial H3CO were 22.06 +/5.28. The most frequent findings on high resolution computerized tomography findings were: thickening of the peribronchovascular space (90%), followed by intralobular septa thickening (50%), subpleural septa thickening (30%), bronchioectasis (40%), mosaic image of perfusion (40%) and pulmonary condensation zones (30%). Two patients required non-invasive mechanical ventilation which was set to low exhaled tidal volume of 200mL for the patient weighing 42kg and 300mL for the patient weighing 60kg. We believe that the findings on the HRCT in these patients represent a precocious interstitial lung lesion; for which we consider that an early intervention could prevent the disease progression and the onset of the refractory phase that subsequently leads to hypoxemia and diffuse alveolar damage","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114558070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Pneumothorax and Facial Papules: Birt-Hogg-Dubé Syndrome","authors":"K. Herring, S. Reed, D. O'hearn, C. White, K. White, E. Simpson","doi":"10.5580/253","DOIUrl":"https://doi.org/10.5580/253","url":null,"abstract":"Spontaneous pneumothorax typically occurs sporadically, however, familial cases occur. We report a case of familial spontaneous pneumothorax secondary to Birt-Hogg-Dubé syndrome (BHDS) diagnosed after the development of characteristic facial papules.BHDS is an autosomal dominant genodermatosis characterized by a triad of spontaneous pneumothorax, facial papules, and renal neoplasms. Clinicians should perform cutaneous exams and ask about a family history of facial papules in patients with familial spontaneous pneumothorax to identify this syndrome and consider screening for underlying renal neoplasms.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"164 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123179332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and Characterization of Pulmonary Surfactant-Super Oxide Dismutase Liposomes","authors":"Qin Wu, Q. Xing, Yuanjie Pan","doi":"10.5580/20b","DOIUrl":"https://doi.org/10.5580/20b","url":null,"abstract":"Objective: To prepare pulmonary surfactant-superoxide dismutase (PS-SOD) Liposomes and analyze the biological characteristics of them. Methods: To prepare PS-SOD Liposomes with rotary evaporation method and analyze the formulation and bioactivity of them, including shape, size, encapsulating ratio, antioxidant activity and surface tension. Results: The PS-SOD Liposome is a kind of ivory white suspension and presents to be a fairly homogeneous spherical article with a mean grain size of 0.463±0.223μm. There is no change in antioxidant activity before and after SOD being encapsulated to be PS-SOD Liposomes. No difference has been found in surface tension between PS and PS-SOD Liposomes. Conclusion: PS-SOD Liposomes can be successfully prepared through rotary evaporation method and maintain stable biological activities both of PS and SOD. Source of financial support: National Natural Science Foundation of China, NO.30471714;","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128988762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fungal ball presenting as Haemoptysis","authors":"S. Kant, S. Verma","doi":"10.5580/1a2b","DOIUrl":"https://doi.org/10.5580/1a2b","url":null,"abstract":"Aspergillus species are ubiquitous molds found in organic matter. Aspergillus primarily affects the lungs, causing 4 main conditions likes, allergic bronchopulmonary aspergillosis (ABPA), chronic necrotizing pulmonary aspergillosis (CNPA), aspergilloma, and invasive aspergillosis. The term aspergilloma (fungal ball) was first used by Dave almost a century later to describe a discrete lesion that classically colonizes the cavities of healed pulmonary tuberculosis and other fibrotic lung diseases 1. The true incidence of aspergilloma is exactly not known. Aspergilloma develops from secondary colonization of preexisting lung cavities.. Natural history of aspergilloma is variable. Aspergilloma clinically presented as mild to severe hemoptysis, which may be life threatening2. Here we are presenting a case of pulmonary aspergilloma in a 55 year old, non smoker male, who presented as recurrent haemoptysis.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116465304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}