A. Barretto, Maria Alice Bragagnolo Batalha, L. Meguins, F. Nascimento, Ajalce de Jesus Leão Janahú
{"title":"Late Onset Post-Pneumonectomy Empyema: An Uncommon Complication In A Brazilian Amazon Man.","authors":"A. Barretto, Maria Alice Bragagnolo Batalha, L. Meguins, F. Nascimento, Ajalce de Jesus Leão Janahú","doi":"10.5580/9f3","DOIUrl":"https://doi.org/10.5580/9f3","url":null,"abstract":"Post-pneumonectomy empyema (PPE) is an uncommon but possibly life-threatening condition. It has a strong association with bronchopleural fistula (BPF), which acts as a continued source of infection into the thoracic cavity and increases mortality. We describe the case of a Brazilian Amazon man that evolved empyema caused by Escherichia coli in the thoracic cavity associated with bronchopleural fistula 19 years after pneumonectomy. This case reinforces the importance of an early suspicion of PPE to avoid diagnostic delay and improve outcomes.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"279 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133948479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Superior Tubercular Mediastinal Cyst Presenting As A Neck Mass","authors":"S. Verma, K. Narayan","doi":"10.5580/1361","DOIUrl":"https://doi.org/10.5580/1361","url":null,"abstract":"We describe a case of Tuberculous cyst in the superior mediastinum presenting curiously as a supraclavicular swelling. Diagnosis was confirmed by doing a CT scan and FNAC of the neck swelling. Patient was successfully treated with a six month course of antituberculous chemotherapy.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"224 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132001758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Foreign body presenting as a persistent lung infiltrate","authors":"J. Cos, G. Fuentes, E. Sy, L. Menon","doi":"10.5580/1126","DOIUrl":"https://doi.org/10.5580/1126","url":null,"abstract":"Complete clinical history and a high index of suspicion is the mainstay for the diagnosis and management of foreign body aspiration. Radiographic imaging can often detect the presence of a foreign body even when there is no clinical suspicion. In the case presented here, computerized chest tomogram (CT) played an important role in the detection of an intra bronchial radioopaque foreign body which was not visible on plain chest roentgenogram (CXR). CT was also useful in demonstrating patency of the airway after bronchoscopic removal of the foreign body.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121895584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Okojie, M. Ebomoyi, C. Ekhator, C. Emeri, J. Okosun, G. Onyesu, O. Uhuonrenren, J. Atima
{"title":"Review Of Physiological Mechanisms Underlying The Use Of Garcinia Kola In The Treatment Of Asthma","authors":"A. Okojie, M. Ebomoyi, C. Ekhator, C. Emeri, J. Okosun, G. Onyesu, O. Uhuonrenren, J. Atima","doi":"10.5580/2909","DOIUrl":"https://doi.org/10.5580/2909","url":null,"abstract":"Historically, plants have provided a source of inspiration for novel drug compounds, as plant derived medicines have made large contributions to human health and well-being. Their role is two ways in the development of new drugs: (1) they may become the basis for the development of new medicine i.e. a natural blueprint for the development of new drugs, or (2) a phytomedicine to be used for the treatment of disease. Though there is availability of various orthodox drugs for the treatment of respiratory track diseases in Nigeria, there is increase in the search for herbal remedies. The seeds of Garcinia kola (GK) forms a major part of the herbal preparation used in traditional African medicine practice for the treatment of various respiratory tract diseases including asthma. Because of the importance of GK as a herb commonly used in herbal medicine for the treatment of asthma, it becomes necessary to find out the physiological mechanism(s) underlying its use. This paper reviews the function(s) of its phytochemical contents and how they are beneficial in the treatment of asthma. Our review showed that xanthone and flavonoid which are its major phytochemical contents inhibit calcium influx and histamine release stimulated by IgE dependent ligands respectively. In conclusion, Garcinia kola appears to be very promising in the treatment and management of asthma.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114733583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mlika, Aida Ayadi-Kddour, Samira Friaa-Meraï, A. Marghli, T. Kilani, F. Mezni
{"title":"The so called pulmonary sclerosing hemangioma","authors":"M. Mlika, Aida Ayadi-Kddour, Samira Friaa-Meraï, A. Marghli, T. Kilani, F. Mezni","doi":"10.5580/b7f","DOIUrl":"https://doi.org/10.5580/b7f","url":null,"abstract":"Background: The so called pulmonary sclerosing hemangioma (PSH) is categorized as a miscellaneous tumour in the new 1999 World Health Organization.Aims: Our objectives are to report 2 cases of PSH with documented radiological and pathological features, to make a review of the literature about the origin, the means of diagnosis, the treatment and the prognosis of this rare and benign tumour.Materials and methods: We report the cases of 2 patients aged 60 and 38 years that presented non specific respiratory signs. The radiological findings were challenging in both cases and the diagnosis was based on histological findings. one case was difficult because of the presence of many granulomas dealing with the diagnosis of tuberculosis which is endemic in our country.Conclusion: PSH are benign tumours with a good behaviour. Although the progress made in radiological techniques to elucidate these lesions, the diagnosis remains based on histological findings.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132494022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coccidioidomycosis In A Cancer Hospital","authors":"A. Huaringa","doi":"10.5580/2926","DOIUrl":"https://doi.org/10.5580/2926","url":null,"abstract":"Study objective: Coccidioidomycosis is a fungal disease that is known to cause pulmonary complications and significant derangement in immunocompromissed hosts. We conducted this study to evaluate the behavior of this disease in our unique patient population.Design: A retrospective clinical study.Patients and setting: We studied the records of all patients with coccidioidomycosis diagnosed at The University of Texas, M.D. Anderson Cancer Center, a university tertiary hospital from January 1956 to December 1994.Results: We obtained 20 record numbers of patients with coccidioidomycosis. Fifteen patients (75%) were asymptomatic with an abnormal chest-X ray. Five patients (25%) had: chest pain (2), dyspnea (1), cough (1), and weight loss (1). Solitary pulmonary nodule was found is 55% of patients, followed by focal infiltrates (25%), multiple nodules (10%), and cavitary lesions (10%). The diagnostic procedures were Open lung biopsy (OPL), Fine needle aspiration (FNA), Bronchoscopy, and Serology. Higher sensitivities were associated with OPL and FNA. Sixteen patients underwent a thoracotomy as a diagnostic and therapeutic procedure. Three patients were medically treated with fluconazole, and one was lost to follow up. None of our patients were in the immunosupressed category.Conclusions: Coccidioidomycosis has a relatively infrequent occurrence in our patient population. Bronchoscopy and serology had low diagnostic yields. Transthoracic fine needle aspiration (FNA) needs to be considered, since coccidioidomycosis does respond to medical treatment, in order to avoid unnecessary ablative surgery. Abbreviations: FNA = Fine needle aspiration. OPL = Open lung biopsy.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130336227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mlika, A. Ayadi-Kaddour, L. Kochbati, S. Hantous-Zannad, F. Mezni
{"title":"Primary malignant germ cell tumours","authors":"M. Mlika, A. Ayadi-Kaddour, L. Kochbati, S. Hantous-Zannad, F. Mezni","doi":"10.5580/25d5","DOIUrl":"https://doi.org/10.5580/25d5","url":null,"abstract":"Study objectives : the aim of this enquiry was to perform a retrospective review on patients treated for primary malignant mediastinal germ cell tumours (PMMGCT) between 1992-2008, to specify their clinical characteristics, their prognostic factors and to evaluate the current therapeutic strategies.Patients: we report a study about 8 patients with seminoma in 3 cases, yolk sac tumour (YST) in 2 cases, embryonal carcinoma (EC) in 1 case, choriocarcinoma in 1 case and teratocarcinoma in 1 case. Pathologic diagnoses were confirmed in all cases by surgical biopsy and a resection of the residual mass in 2 cases.Results: all the patients were male with a mean age of 32 years (range, 16 to 63 years). Only one patient was asymptomatic. The most frequent symptoms were cough (87.5%), chest pain (50%) and dyspnea (50%). The 8 tumours were located in the anterior mediastinum. One patient with EC didn’t received any treatment because of the rapid evolution of the disease. The 7 others received pre-operative chemotherapy and 3 patients received a second-line chemotherapy because of the persistence of viable tumours in one case (YST) and a resistance to the first chemotherapy in 2 cases (seminoma and teratocarcinoma). The overall 2-year survival of patients with seminoma was 100% towards 25% for those with nonseminomatous tumours. The patients with satge I disease survived for a mean period of 3 years.Conclusion: The PMMGCT cause generally a diagnostic challenge because of the difficulty of their resection and the little size of the biopsy specimen. Besides, the absence of a primary gonadal localization may be difficult to establish. These tumours have a worse prognosis than their gonadal counterparts. Prognostic factors are multiple and not accurate. The most relevant ones seem to be the histological type and the disease stage.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121099112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous Pneumomedistinum in Pneumocystis Pneumonia and Acquired Immunodeficiency Syndrome","authors":"D. Rosen, J. Blasberg, R. Ashton, C. Connery","doi":"10.5580/20c2","DOIUrl":"https://doi.org/10.5580/20c2","url":null,"abstract":"Pneumomediastinum is defined as air within the mediastinal cavity, and is usually accompanied by subcutaneous emphysema. It is a relatively uncommon and infrequently reported entity, specifically in patients with AIDS. Reported is a 39-year-old male with chest pain and radiologic findings of tension pneumomediastinum, prompting emergent surgical consultation for decompression. Due to the patient's hemodynamic stability, a conservative approach of observation was employed. Over the following days the patient's pneumomediastinum decompressed naturally into the neck and eventually resolved. Radiographic studies are invaluable in diagnosing and following individuals with pneumomediastinum, but tension pneumomediastinum by radiologic evidence alone is not an indication for surgical intervention.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114906098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orodispersable Tablets of Salbutamol Suphate using combinational approaches for disintegration: For Effective Management of Asthma","authors":"N. Seth, J. Goswami, Shailesh Sharma, G. Gupta","doi":"10.5580/27d8","DOIUrl":"https://doi.org/10.5580/27d8","url":null,"abstract":"Asthma is an inflammatory disorder that results in the obstruction of air pathways and causes difficulty in breathing. Amongst the currently available means of treatment, conventional oral dosage forms are associated with lag time and delayed onset of action. Salbutamol sulphate is a selective β2 receptor agonist widely used as bronchodilator and forms part of initial therapy in chronic as well as acute asthma. In present work an attempt has been made to formulate Orodispersible Tablets (ODT) of salbutamol sulphate by superdisintegrant addition and sublimation technique. ODTs containing subliming material were subjected to drying under vacuum to aid in sublimation and make tablets porous. It was concluded that tablets prepared by addition of sublimation method has less disintegration time than those prepared by superdisintegrantx. These tablets give fast release of salbutamol sulfate which results in fast action in asthmatic attack.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131029576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Battal, U. Bozlar, F. Ors, Suela Nikolla, M. Taşar, C. Tayfun
{"title":"Superior vena cava syndrome caused by bronchogenic cyst: Report of a case","authors":"B. Battal, U. Bozlar, F. Ors, Suela Nikolla, M. Taşar, C. Tayfun","doi":"10.5580/22e","DOIUrl":"https://doi.org/10.5580/22e","url":null,"abstract":"Superior vena cava (SVC) syndrome may be caused by intrathoracic benign and malignant processes. Although bronchogenic cyst is a rare cause of the superior vena cava syndrome (SVCS), it should be considered because it is a potentially treatable lesion. In this report, we present clinical and radiological features of a case of symptomatic mediastinal bronchogenic cyst causing SVCS.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132630251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}