The Internet Journal of Pulmonary Medicine最新文献

{"title":"Pulmonary Alveolar Microlithiasis Scintigraphic Features","authors":"J. Hephzibah, R. Oommen, Bala Mugesh, J. Pradhip","doi":"10.5580/2506","DOIUrl":"https://doi.org/10.5580/2506","url":null,"abstract":"A 35-year-old female patient presented with a history of nonspecific chest pain and cough for one year. Spirometric studies excluded an obstructive ventilatory defect . Lung volume study findings were consistent with a moderate restrictive ventilatory defect with Total Lung capacity of 2.15L (51.6% of predicted). Diffusing capacity for the alveolar volume ventilated was reduced. Plain chest radiograph showed sand-like opacities, diffusely scattered, bilateral, micronodular areas of radioopacity of calcific densities throughout the lungs with the classic “sandstorm” pattern throughout both lungs predominantly in the lower zones (Fig: 1). Figure 1 Figure 1: Plain chest radiograph showing sand-like opacities, diffusely scattered, bilateral, micronodular areas of radioopacity of calcific densities throughout the lungs with the classic “sandstorm” pattern throughout both lungs predominantly in the lower zones. Computerized tomographic scan revealed diffuse bilateral calcified fine nodular pattern with extensive septal thickening (Fig: 2). Pulmonary Alveolar Microlithiasis Scintigraphic Features 2 of 4 Figure 2 Figure 2: Computerized tomographic scan showing diffuse bilateral calcified fine nodular pattern with extensive septal thickening. Figure 3 Figure 3: Tc-99m methylene diphosphonate (MDP) Bone scintigraphy showing intense bilateral uptake of the radiopharmaceutical in the lungs. Bone scintigraphy along with chest radiography and computerized tomography contributed to the diagnosis of Pulmonary Alveolar Microlithiasis in this patient. DISCUSSION Pulmonary alveolar microlithiasis is a rare disease of unknown etiology, characterized by the presence of calcific concretions in the alveolar spaces, intra-alveolar development and deposition of microliths or calcispherytes consisting of calcium phosphate1 The progression of the disease is generally very slow. Study of the calcium metabolism in many reported cases, however, reveals no derangement of serum calcium levels as in this patient who was normocalcemic, though elevated serum calcium and renal stones have been recorded in some cases.2, 3 Pulmonary function studies demonstrate a tendency toward a restrictive pattern. Chest roentgenography, high-resolution computed tomographic, and technetium-99m lung scan are useful in the diagnosis. Bone scintigraphy can be useful in the detection of early pulmonary calcifications, which have been associated with impaired pulmonary function and, due to their size, are generally not detected by X-ray. Bone scintigraphy may add helpful information in the case of nonspecific CT findings. Bone scan usually shows intense bilateral uptake of the radiopharmaceutical in the lungs.4 Differential diagnosis of diffuse lung uptake in bone scans includes patients with hyperparathyroidism, Hodgkins lymphoma, Sarcoidosis, Wegener's vasculitis, Primary amyloid, renal failure and Pneumocystis carinii.5 CORRESPONDENCE TO Dr Regi Oommen MD, Professor and Head, Department of Nuclear","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"442 1-2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132313450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenoid Cystic Carcinoma Of The Trachea Treated As COPD","authors":"A. Papaioannou, K. Kostikas, V. Kouloumenta, D. Papadopoulos, C. Pastaka, K. Gourgoulianis","doi":"10.5580/1d91","DOIUrl":"https://doi.org/10.5580/1d91","url":null,"abstract":"Primary adenoid cystic carcinoma of the trachea is a rare malignant neoplasm. We present the case of a 64 year old man, exsmoker, who presented at the University Hospital of Larissa complaining of dyspnea on exertion, chest tightness and wheezing for more than one year. By that time the patient had been misdiagnosed and treated as chronic obstructive respiratory disease (COPD) without any improvement of his symptoms. Computed tomography of the chest revealed a tumor which caused a 90% obstruction of the trachea lumen. Bronchoscopy was performed and the pathological diagnosis was adenoid cystic carcinoma of the trachea. The literature is reviewed.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121784256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung Cancer presenting as Pneumonia in Pregnancy","authors":"H. Mehta, R. Sadikot, R. Bahuva","doi":"10.5580/1f09","DOIUrl":"https://doi.org/10.5580/1f09","url":null,"abstract":"A 37 year old female with B human chorionic gonadotropin(B-HCG) secreting occult lung carcinoma presenting with cough, dyspnoea and CXR infiltrate was diagnosed as having pneumonia till she presented few months later with advanced disease. Lung Cancer could secrete various hormones including B HCG, Anti diuretic hormone, Para thyroid hormone related peptide (1, 2, 3). Young females presenting with suspicious infiltrate on Chest X ray and who need CT scan of the chest are likely to have Urine pregnancy tests which being B-HCG based is likely to be positive in B HCG secreting Lung cancer. These could delay a potentially important investigation and lead to misdiagnosis and early closure. Though this confusion is logical it has so far not been reported for Lung cancer to be diagnosed as having pneumonia in pregnancy only to be subsequently diagnosed as having Large cell Lung Cancer. It is thus important to consider Lung cancer with B-HCG secretion as an important differential in young females with similar presentation as it could have long term implications in patients' management.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117022580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous expulsion of aspirated teeth in left lung following maxillofacial trauma: Case Report","authors":"S. Kant, S. Verma, V. Mahajan","doi":"10.5580/776","DOIUrl":"https://doi.org/10.5580/776","url":null,"abstract":"Aspiration of teeth secondary to maxillofacial trauma is uncommon and its spontaneous removal after coughing is a rare clinical condition. Hereby we report such type of case in fifty years old male.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133897428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse pulmonary lymphangiomatosis in a 26-year-old man","authors":"D. Feng, J. Woytash","doi":"10.5580/99a","DOIUrl":"https://doi.org/10.5580/99a","url":null,"abstract":"Diffuse pulmonary lymphangiomatosis is a very uncommon disease, and is caused by abnormal development and proliferation of the lymphatic system. It is seen predominantly in children, exceptionally in adults, and affects both sexes equally. The diagnosis is usually made by biopsy. We report a case of a 26-year-old patient who presented with a 12 month history of progressive chronic cough and dyspnea. His chest CT image mimicked interstitial lung disease. Histopathologic examination showed marked thickening of the pleura with numerous dilated irregular thin-walled lymphatic vessels. The diagnosis was confirmed to be diffuse pulmonary lymphangiomatosis by lung tissue biopsy.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129105568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity Hypoventilation Syndrome (Pickwickian syndrome) with Obstructive Sleep Apnoea","authors":"R. Kushwaha, S. Verma, V. Mahajan, R. Singh, R. Prasad","doi":"10.5580/18ed","DOIUrl":"https://doi.org/10.5580/18ed","url":null,"abstract":"A 48 year old obese male with symptoms of obesity hypoventilation syndrome (Pickwickian syndrome) and obstructive sleep apnoea was admitted to our department. He was put on non invasive positive pressure ventilation and showed dramatic clinical response.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114438247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Function Tests Abnormalities In Parkinson Disease","authors":"H. Mikaelee, M. Yazdchi, K. Ansarin, M. Arami","doi":"10.5580/e0f","DOIUrl":"https://doi.org/10.5580/e0f","url":null,"abstract":"Objective: In patients with Parkinson's disease (PD) and other extrapyramdial disorders, respiratory problems commonly contribute to morbidity and mortality. The aim of this study is to investigate the characteristics of pulmonary function tests (PFT) abnormalities in patients with PD. Materials and Methods: PFTs performed in 25 patients suffered PD (19 male 69%, 6 Female 24 % ) without known respiratory and cardiovascular disease and no history of smoking and 25 healthy individuals as an age and sex matched control group. We obtained Body plethysmographic measurements of lung volumes and respiratory determinations of PFT. PD severity was evaluated by Hoehn and Yahr staging. Results: The mean age of PD onset was 58.8±11.6 years. 44 % (n= 4) of patients in H-Y Group 1, and 75 % (n= 6) in group 2 and 3 and 75% (n=6) in group 4 and 5 had abnormal PFT values. Between various tests, the Residual Volume (RV>120 % of normal value); Forced Vital Capacity (FVC<80 % of normal value) and FEV1 / FVC Ratio<75 % of normal ratio, were significantly abnormal in patients with PD compared with the controls, (p<0.05). Also obstructive pulmonary function disorders were significantly common in patients, (p<0.04). Conclusions: Obstructive pattern of respiratory abnormalities is the most common type of PFT impairment in PD patients. The evaluation and rehabilitation of pulmonary disorders should be routinely included in the management of PD patients. This study has supported by Research Assistance of Tabriz University of Medical Sciences","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114590645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Amount Of Smoking With Chronic Cough And Sputum Production","authors":"M. Movahed, N. Milne","doi":"10.5580/1727","DOIUrl":"https://doi.org/10.5580/1727","url":null,"abstract":"Background: Smoking is a major cause of respiratory disease. We evaluated the association between the amount of chronic smoking with chronic cough and sputum production as a surrogate of pulmonary abnormalities Methods: 139 patients who underwent left ventricular ejection fraction measurement for clinical reasons, were evaluated for the presence of chronic cough and sputum production with reference to the length and amount of smoking. Results: The length and amount of smoking increased the risk of sputum production (smoking less than 10 pack years (9 of 48 18.8% vs smoking more than 10 pack years 38 of 108, 35.2%, OR: 1.3 CI 1.03-1.5, p=0.03). The length of smoking over 50 pack years vs less than 5 pack years was also significantly associated with chronic cough (24 of 31, 77.4% vs 22 of 52, 42.3%, OR: 4.7 CI: 1.7-12.7, p =0.002). Furthermore the mean length of smoking was significantly longer in patients with chronic cough (34.9  38.2 vs 49.1  40.2, p=0.03) or increased sputum production (34.6 39 vs 56.0  40.4, p=0.002). Conclusion: Increasing in length and amount of smoking is associated with increase risk for chronic cough and sputum production consistent with dose dependent negative effect of chronic smoking.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"228 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122151418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Cheyne-Stokes Respiration In An Awake Patient After Stroke","authors":"E. Garcia-Pachon","doi":"10.5580/332","DOIUrl":"https://doi.org/10.5580/332","url":null,"abstract":"Cheyne-Stokes respiration (CSR), a disorder characterised by recurrent central apnoeas alternating with a crescendodecrescendo pattern of tidal volume, is relatively frequent in conscious patients after stroke. However, this respiratory disorder is, in general, not clinically detected probably due to slight intensity and scant clinical consequence. We report the case of a 70year-old-woman who experienced severe CSR after a stroke with severe desaturation during the apnoeic periods. Treatment with oxygen, continuous positive airways pressure and noninvasive ventilation was unsuccessful. With pharmacological therapy (acetazolamide, medroxyprogresterone and theophylline) the CSR resolved.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"42 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114040261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alveolar Oxygen And Carbon Dioxide Tensions During Pregnancy, Measured With A Novel Technique","authors":"M. Litos, K. Hadjistavrou, A. Xygakis, A. Antsaklis, J. Jordanoglou","doi":"10.5580/ee5","DOIUrl":"https://doi.org/10.5580/ee5","url":null,"abstract":"Alveolar O2 and CO2 tensions (PAO2 and PACO2) and alveolar-to-arterial oxygen difference (P(A-a)O2) during pregnancy have been calculated with mathematical formulas that require arterial blood taking and are based on the assumption that alveolar and arterial CO2 tensions are equal (P(A-a)CO2=0). The aim of this study was to investigate the changes of alveolar gas tensions during pregnancy, using a novel non-invasive technique. PAO2, P(A-a)O2, PACO2 and P(A-a)CO2 were measured in 10 healthy volunteers during the 3rd trimester of pregnancy and when not pregnant. During pregnancy, the PAO2, P(A-a)O2, PACO2 and P(Aa)CO2 values (in mmHg with SD) were: 101.67 (8.931), 0.78 (7.848), 26.05 (4.670), -4.86 (3.257). When not pregnant the respective values were: 95.75 (8.976), 3.56 (6.047), 35.28 (1.618), -2.63 (1.532). P(A-a)CO2 was different to zero and its absolute value was increased during pregnancy (p=0.01). We detected a change in P(A-a)CO2 during pregnancy suggesting an increase of the shunt, possibly caused by the elevation of the diaphragm and the collapse of alveoli at the lung bases. The changes in PAO2 and PACO2 can be attributed to the hyperventilation of pregnancy and are comparable to the literature.","PeriodicalId":284620,"journal":{"name":"The Internet Journal of Pulmonary Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114150665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}