Journal of Clinical and Cosmetic Dermatology最新文献

{"title":"Treatment of Deep Wrinkles with Superficial Application Technique of Hyaluronic Acid","authors":"M. D. da Cunha, Ana Lúcia Gonzaga da Cunha, L. Gasques, C. D. M. Machado Filho, F. A. Fonseca","doi":"10.16966/2576-2826.177","DOIUrl":"https://doi.org/10.16966/2576-2826.177","url":null,"abstract":"Introduction: Throughout the aging process, skin is subject to continuous structural, cellular and molecular modifications that affect not only its mechanical properties but also its biological and physiological functions, which clinically is manifested by dry skin, loss of elasticity and the consequent appearance of fine lines, wrinkles and creases, representing a therapeutic challenge with a difficult solution. Objective: to describe the superficial application technique of cohesive polydensified matrix hyaluronic acid (Belotero soft®) for the resolutive treatment of superficial perioral, periorbicular and lateral wrinkles and creases of the face. Conclusion: The superficial and transversal application technique showed to be ideal for the treatment of wrinkles and superficial creases, without description of important adverse effects or Tyndall effect with the cohesive polydensified matrix hyaluronic acid.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130148474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatitis Neglecta: An oft Missed Diagnosis","authors":"A. S, Gandhi V","doi":"10.16966/2576-2826.149","DOIUrl":"https://doi.org/10.16966/2576-2826.149","url":null,"abstract":"Dermatitis neglecta, also known as ‘dirty dermatosis’ or ‘unwashed dermatosis’ is an uncommon yet noteworthy entity as it can be easily misdiagnosed for many other dermatoses [1]. This entity was first reported by Poskitt L, et al. [2]. The probable cause is lack of proper cleansing of skin leading to accumulation of sweat, sebum, and exfoliated corneocytes with growth of micro-organisms. This results in formation of a layer of adherent scale crust over the affected part [3]. In some patients underlying disorders like psychiatric illness [4] or neurological diseases [5] have been described. Clinical presentation is in the form of hyperkeratotic verrucous plaques mimicking a variety of specific dermatoses like seborrheic dermatitis, pemphigus foliaceous, verrucous epidermal naevus, darier’s disease and terra firma forme dermatoses [4].","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124889422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of a Topical Agent Containing Tranexamic Acid, Niacinamide and Kojic Acid in Melasma","authors":"X. X, C. L, Xu Z, Jin S, Zhang C, Xiang L","doi":"10.16966/2576-2826.160","DOIUrl":"https://doi.org/10.16966/2576-2826.160","url":null,"abstract":"Background: Melasma is a common pigmentary disorder in Asian women.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129047069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photosensory Function, Reception and Response in Human Skin","authors":"Smith Djm","doi":"10.16966/2576-2826.164","DOIUrl":"https://doi.org/10.16966/2576-2826.164","url":null,"abstract":"Human skin has a photosensory system comprised of several opsins, light-sensitive proteins, and their signalling pathways as peripheral sensors and effectors mainly orchestrated through the melanocyte but also involving keratinocytes, fibroblasts and hair follicle cells. It has been shown that UVA radiation can lead to an Immediate Pigment Darkening (IPD) response in melanocytes. Necessity of a protective response is obvious but this system feeds into a neuronal and hormonally-mediated centralised system of clock-like responses that not only respond to immediate threats but also demonstrating an established mechanism to anticipate changes in the day/night and seasonal cycles that have profound effects on the behaviour of the organism as a whole.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134511412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keloid Excision with Debulking Technique on the Lobule Auricle Sinistra","authors":"Syarif Fr, Lestari S, Monica Pw, Syarif Sk","doi":"10.16966/2576-2826.165","DOIUrl":"https://doi.org/10.16966/2576-2826.165","url":null,"abstract":"Introduction: Keloids are fibroproliferative lesions caused by abnormal wound healing and are characterized by excessive collagen deposits that cannot heal spontaneously. Keloid in the ear is a challenging condition to be treated by doctors, especially the large ones. This condition has a psychosocial impact on the patient and a consideration for appearance is often the main reason for patients seeking to cure keloids, although there is a high possibility of keloid recurrence. Out of various keloid therapy options, one method that can be done is surgical excision therapy with debulking technique. Case report: A case of keloids in left ear lobule measuring 2.5 cm × 3 cm is reported after the patient does ear piercing with complaints of slight itch and aesthetical disturbance. Keloids enlarge 6 months after piercing. The case is treated by debulking excision surgery using local anesthesia Pehacain® (lidocaine 2% + adrenaline 1:80,000). At the end of the wound closure, 40 mg of triamcinolone acetone is given. It is regiven one week after the stitches are removed and repeatedly every 2 weeks for 4 times. Excision surgical results are good and the patient feels satisfied. Conclusion: Excision surgery with debulking technique is chosen because of the large size of the lesion and to ensure there is no residual keloid tissue at the site of predilection. Corticosteroid injection is given immediately after excision to decrease fibroblast proliferation, collagen and glycosaminoglycan synthesis and suppress proinflammatory mediators in order to prevent keloid recurrence.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115116538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stability of Two Cross-Linked Hyaluronic Acid Gels for the Treatment of Temporal Fossa Volume Loss: A Preliminary Study Using MRI and Visual Observations","authors":"Micheels P, Besse S, E. B, V. J","doi":"10.16966/2576-2826.172","DOIUrl":"https://doi.org/10.16966/2576-2826.172","url":null,"abstract":"Introduction: Hyaluronic Acid (HA) gels are a commonly used option for correcting facial volume loss. Over the past 2 years, we have been testing the clinical results of two HA gels, without lidocaine, made by the same manufacturer using the patented “Inter- Penetrating NetworkLike” (IPN-Like) cross-linking technology. The aim of this work was to evaluate if there is a difference in the tissue stability and associated clinical outcomes between these two gels. Material and methods: A 67 and 75 years old Caucasian women, from our private aesthetic center, agreed to be injected with the different HA volumiser gel, one in each of their temporal fossae. The Stylage® XL and XXL HA gels (LABORATOIRES VIVACY, Archamps, France) were used for this study. The gels have different concentrations and levels of cross-linking, but have the same indications for correcting facial volume loss resulting from the ageing process. Clinical outcomes included assessing the degree of pain experienced by participants during and after injection using a Visual Analog Scale (VAS). Aesthetic improvement was evaluated using the Merz Analogic Scale® (MAS)® and Global Aesthetic Improvement Scale (GAIS) scales completed by patients and independent experts at different pre-set time-points using photographs taken from the front, profile and three-quarter left and right angles. Moreover, Serial magnetic Resonance Imaging (MRI) scans were used to assess the tissue behavior of the gels immediately after injection and then 6 monthly for 2 years. Results: Both gels led to an improvement in the patients’ clinical outcomes. This improvement persisted over time. The MRI scans showed that, at Day 0, the injected gel was spherical in shape and became elongated by 6 months. This appearance did not change throughout the follow-up period. The scans showed little resorption at 24 months. Conclusion: Despite the relatively advanced age of the two patients and the small quantities of gel injected, the IPN-Like cross-linked hyaluronic acid volumiser gels had a satisfactory sustainable clinical effect as assessed by patients and experts. There was a slight advantage in favor of the gel with the lower HA concentration but higher level of cross-linking (Stylage® XXL). Given the observed persistent effect of the gels in our preliminary observation, it is now important to conduct a larger study with longer follow- up.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114326284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Adding Lidocaine to Hyaluronic Acid Gel for Volume Loss Correction: A Preliminary Observation","authors":"Micheels P, Besse S, E. B, V. J","doi":"10.16966/2576-2826.173","DOIUrl":"https://doi.org/10.16966/2576-2826.173","url":null,"abstract":"Introduction: Although adding a local anesthetic is an effective way to reduce pain during intradermal Hyaluronic Acid (HA) injections, it is not clear if the pain control is as effective when performing injections close to the bone. The primary aim of these preliminary observations was to explore this issue. As a secondary aim, we wanted to assess if the addition of lidocaine alters the behavior of HA gel in the tissues over time. Subjects: Two women provided informed written consent to participate in the study. Participants were blind to the type of HA gel used for either temporal fossa. Methods: A cross-linked HA gel was used for the study. One side was injected with the gel with and the other without lidocaine, in no particular order. Photographs from the front, profile and three-quarter left and right and frontal MRI scans were taken before and just after the injections, then every 6 months for 2 years. Results: The side injected with the gel with lidocaine was significantly less painful than that injected without lidocaine. Both types of gel changed shape on MRI in the first 6 months but stayed stable thereafter till the end of our follow-up at 24 months. Based on MRI, patient reported outcomes and expert assessed aesthetic outcomes, using MAS® and the global aesthetic improvement scale, both types of gel were comparable. Conclusion: The addition of lidocaine to HA volumiser gels reduces pain to a remarkable degree.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128252545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Guided Injection of Hyaluronic Gel Filler in the Temples: A Report of Two Cases","authors":"P. Micheels, S. Besse, J. Vandeputte","doi":"10.16966/2576-2826.156","DOIUrl":"https://doi.org/10.16966/2576-2826.156","url":null,"abstract":"Introduction: The aim of this case report was to assess the effect of injecting hyaluronic acid gel filler in the temporal fossa for the correction of skeletonisation in this specific anatomical area of the ageing face.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124141992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endocrine Mucin-Producing Sweat Gland Carcinoma: A Case Report and Literature Review","authors":"Cuéllar-Martinez Mc, García-Valencia V, Montoya-Bueno C, Restrepo-Molina R","doi":"10.16966/2576-2826.171","DOIUrl":"https://doi.org/10.16966/2576-2826.171","url":null,"abstract":"Endocrine Mucin-Producing Sweat Gland Carcinoma (EMPSGC) is a rare, low-grade, malignant tumor derived from sweat glands, arising preferentially in skin from the periorbital region. EMPSGC tumors are more frequently found in elderly female patients. To date, only around 70 cases have been reported in the literature [1-3]. Therefore, thorough immunohistochemical characterization of EMPSGC tumors is of pivotal importance to confirm its diagnosis [4-6].","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124514672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Electromyoneurolysis of the Orbicularis Oculi Muscle: A Permanent Substitute of Botulinum Toxinin Crow’s Feet","authors":"Schwember J, Madrid L, Hernández A, Leiva F, K. A","doi":"10.16966/2576-2826.170","DOIUrl":"https://doi.org/10.16966/2576-2826.170","url":null,"abstract":"The skin is exposed to many factors that cause wrinkling and loss of elasticity. For the past 30 years, Botulinum Toxin (BT) injections have been the gold standard of treatment for wrinkle reduction. In this article, the authors propose a permanent treatment for crow’s feet wrinkles: Percutaneous Electromyoneurolysis (PEMN) of the Orbicularis Oculi Muscle (OOM) which blocks muscular and nerve fibers using an electrosurgical unit. This procedure was performed on 34 patients between 2016 and 2021, with the objective of attenuating lateral periorbital wrinkles (crow’s feet) or benign essential blepharospasm. The results were evaluated and deemed successful after a 9-month follow-up. Our study demonstrates the effectiveness and viability of this approach and may lead to future applications in facial aesthetics.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126282686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}