Journal of Clinical and Cosmetic Dermatology最新文献

{"title":"Evaluation and Measurement of the Wrinkle-Reduction Performance of a NonToxin Based Topical Skin Serum on Volunteers","authors":"Knight Am, Paul Sp","doi":"10.16966/2576-2826.159","DOIUrl":"https://doi.org/10.16966/2576-2826.159","url":null,"abstract":"Objective: The primary aim of this study was to evaluate the performance of a commercially manufactured study product-a non-toxin-based topical skin serum-in terms of its wrinkle reducing capability in women concerned about the appearance of their wrinkles.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124891705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a Food Supplement with Collagen Hydrolysate and Micronutrients on Skin Appearance and Beauty Effects: A Randomized, Double-Blind, PlaceboControlled Clinical Study with Healthy Subjects","authors":"Y. Modinger, C. Schon, K. Vogel, M. Brandt, S. Bielfeldt, K. Wilhelm","doi":"10.16966/2576-2826.158","DOIUrl":"https://doi.org/10.16966/2576-2826.158","url":null,"abstract":"Objective: Skin health, skin appearance and skin beauty are influenced by collagen composition of the dermis. Natural aging affects the structural integrity of the collagen network, resulting in drier skin, wrinkle formation and reduced skin elasticity. Orally ingested hydrolyzed collagen reaches the skin tissue and exerts beneficial effects on human skin from within. However, not only collagen peptides, but also micronutrients can beneficially affect skin appearance. Thus, dietary supplements for cosmetic and beauty effects containing combinations of collagen peptides and selected micronutrients are in demand. Aim of this study was to investigate the effect of a food supplement with collagen hydrolysate and micronutrients on skin beauty. The test product was assessed for its capability to reduce wrinkles and to improve skin hydration and collagen structure.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125505657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Uveitis in Patients with Psoriasis: A Cross Sectional Study in Indian Population","authors":"Kulhari A, Gandhi V, Bhattacharya Sn, Sahu Pk, A. An","doi":"10.16966/2576-2826.168","DOIUrl":"https://doi.org/10.16966/2576-2826.168","url":null,"abstract":"Background: Psoriasis is associated with cause specific ocular involvement, uveitis being the most serious. Severity of skin disease, presence of arthritis and HLA B27 positivity may be associated with higher incidence of uveitis.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127169621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Squamous Cell Carcinoma on Discoid Lupus on Photo Protected Area","authors":"Diousse P, N. M, Gueye N, Dione H, Bammo M, S. F","doi":"10.16966/2576-2826.174","DOIUrl":"https://doi.org/10.16966/2576-2826.174","url":null,"abstract":"Introduction: Discoid lupus erythematosus is an autoimmune disease with mainly skin manifestations. Squamous cell carcinoma is a complication of discoid lupus on phototype VI and photoprotected area. We are reporting a case. Observation: It was a 52-year-old man, driver for 30 years, phototype VI, received for a budding lesion of the back evolving for 1 year on discoid lupus erythematosus followed for 10 years. On examination, there was a budding swelling with a bleeding surface of 5cm in diameter resting on a discoid lupus lesion in the lumbar region with discoid plates along the spine. Histology showed moderately differentiated tumor cells with volumeincreased nuclei; nucleolated. He benefited from a carcinological excision followed by chemotherapy and was then lost to follow-up. Discussion: Squamous cell carcinomas are rare on discoid lupus erythematous. The factors incriminated would be chronic inflammatory processes, atrophy, depigmentation, UV rays, microtrauma by friction related to the patient’s profession. Conclusion: Squamous cell carcinoma on discoid lupus erythematous remains a rare cancer in photo protected areas.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127670517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a Hybrid Hyaluronic Acid Gel for the Face and Neck in Men: Pilot Observation on Male Subjects","authors":"Micheels P, Salomon Mm, Bezzola Th","doi":"10.16966/2576-2826.169","DOIUrl":"https://doi.org/10.16966/2576-2826.169","url":null,"abstract":"Introduction: While upper-class men had been taking care of themselves for centuries, this changed somewhat in the first half of the 20th century. And by the 1980s the cult of the body and the metrosexual man had emerged, with a marked upsurge in male cosmetic treatments. There was also an increased demand for treatment of wrinkles such as glabellar lines or nasolabial folds.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":" 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113948361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chitin & Lignin: Turning Food Waste into Cosmeceuticals","authors":"M. P, Chen Hd, Gao Xh, Morganti G, Febo D","doi":"10.16966/2576-2826.135","DOIUrl":"https://doi.org/10.16966/2576-2826.135","url":null,"abstract":"The ~3 billion tons/year of worldwide food waste represents a great environmental problem to be positively solved. Thus, it may be used as an interesting raw material to be transformed in useful biodegradable goods. In the same way an agricultural correct waste management can prevent further environmental damage. For both these waste it is possible to obtain chitin and lignin respectively to be used for producing biodegradable tissues to make, for example, baby diapers, beauty masks and advanced medications, according to the EU research project PolyBioSkin. This paper reports some results obtained by the use of both nano-chitin and nano-lignin.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"662 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132191657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Galactomyces Ferment Filtrate Suppresses Reactive Oxygen Species Generation and Promotes Cellular Redox Balance in Human Melanocytes via Nrf2-ARE Pathway","authors":"Cooper Jkw, A. Koshoffer, A. L. Kadekaro, T. Hakozaki, R. Boissy","doi":"10.16966/2576-2826.138","DOIUrl":"https://doi.org/10.16966/2576-2826.138","url":null,"abstract":"Galactomyces Ferment Filtrate (GFF, PiteraTM) is a yeast derived extract used as a moisturizing agent in cosmetics. GFF demonstrates anti-aging, barrier health, and putative hypopigmenting effects in skin, prompting vitiligo therapeutic potential; thus, the antioxidant properties of GFF are the focus of our study. Foreskin derived Normal Human Epidermal Melanocytes (NHEM) were treated with 0-10% GFF. Cell viability was determined by MTT assay. Reactive Oxygen Species (ROS) were assessed by fluorescent microscopy and luminescence. The mRNA and protein expression were quantitated by RNA-seq transcriptome profiling and Western blot analyses, respectively. GFF sustained cell viability and combated ROS generation in NHEM challenged with 4-Tertiary Butylphenol (4TBP). GFF also suppressed Hydrogen Peroxide (H2O2) generation in NHEM irradiated with Ultraviolet-B (UVB). RNA-seq and Western blot analyses revealed that GFF significantly altered the mRNA and protein levels of phase II antioxidant enzymes (HO1, NQO1, TXNRD1) mediated by nuclear factor, erythroid 2-like 2 (Nrf2)-Antioxidant Response Element (ARE) pathway. HO1 was highly inducible in both the cytoplasm and nucleus in NHEM (6and 8-fold). Altogether, GFF effectively suppresses the generation of ROS in part by up regulating the endogenous levels of antioxidant enzymes via activating the Nrf2-ARE pathway; thus, priming and protecting NHEM against oxidative assaults.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130118668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blepharoplasty and Eyelid Resurfacing: Blepharolaser","authors":"J. Schwember, G. Schwember, M. Rivas, L. Madrid, A. Kurtzig","doi":"10.16966/2576-2826.161","DOIUrl":"https://doi.org/10.16966/2576-2826.161","url":null,"abstract":"Blepharoplasty is a demanding cosmetic surgery. When surgery is being considered, ophthalmic tests, such as visual acuity, eye pressure and tear film, are important. Additional treatments have been incorporated to the traditional surgical procedure to improve periorbital skin of which the most accepted is laser resurfacing. In this study, the authors report their experience with 63 patients operated on between 2014 and 2020 and propose an algorithm to apply Er:YAG laser to the eyelid skin.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124578612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxicity, Allergenicity and Carcinogenicity: Some Hope for Innovative Cosmeceutical Products?","authors":"Guertin Pa","doi":"10.16966/2576-2826.136","DOIUrl":"https://doi.org/10.16966/2576-2826.136","url":null,"abstract":"The safety of cosmetic and cosmeceutical products has been questioned by several independent experts. A plethora of ingredients, additives and preservatives, used in their preparation are indeed allergenic, toxic, mutagenic and carcinogenic. Despite warnings from Dr. David Suzuki and others a few years ago, little has been done by authorities or the industry to improve the safety of these products. Some companies have instead begun proposing dermatological creams and serums composed of natural ingredients. However the safety profile of those newer products for the intended indication remains generally to be determined clearly. Authorities such as the US Food and Drug Administration, Health Canada and European Medicines Agency should be asked to implement new rules to improve regulations before approval and commercialization of cosmetic and cosmeceutical products that include so-called ‘natural’ ingredients or not.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"264 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132213801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To Evaluate the Efficacy and Safety of Autologous Platelet Rich Fibrin Matrix in the Treatment of Non-Healing Ulcer of Various Aetiology","authors":"B. Shreyansh, M. Mehta, K. Dilip","doi":"10.16966/2576-2826.147","DOIUrl":"https://doi.org/10.16966/2576-2826.147","url":null,"abstract":"extraction [3] and transplant on the wound bed, epidermal grafting, etc. Recently, the focus has shifted on to growth factors which include therapies like recombinant growth factors and Platelet Rich Plasma (PRP). Platelet Rich Fibrin Matrix (PRFM), a next generation PRP is the latest addition which is based on the premise of slow and sustained release of growth factors [4] mimicking the natural wound healing process. The concentration of platelets is higher in PRP but a study showed that, when incorporated into fibrin, the mean concentration of growth factors in the platelet concentrates was three times or more than that observed with conventional platelet-rich plasma. The membrane can be easily placed on the ulcer with minimal chances of displacement. Thus giving PRFM an edge over PRP in wound healing. Autologous PRFM is prepared from patients own blood thus being free from risk of communicable pathogens, is easy to prepare with long lasting as well as good clinical results. the Efficacy and Safety of Autologous Platelet Rich Fibrin Matrix in the Treatment of Non-Healing Ulcer of Various Abstract Rationale: Chronic Non-Healing Ulcers (NHU) is those which persists for more than 6 weeks and may be due to underlying factors like venous stasis, peripheral neuropathy, immobility, etc. Chronic ulcers are associated with decreased quality of life and also pose a financial burden on the patient as well as society. The failure of NHU to respond to the various modalities available lead to the search for growth factors requisite for wound healing resulting in the development of Platelet Rich Plasma (PRP). Platelet Rich Fibrin Matrix (PRFM) is a next generation of PRP that has shown promising result in our study. Objectives: This study was done to evaluate the efficacy and safety of autologous platelet rich fibrin matrix in the treatment of non-healing ulcer of various aetiology. Results: All the ulcers responded to the treatment with decrease in pain and discharge beginning from first sitting. The mean time to ulcer healing was 6.43+2.33 weeks. There was 100% improvement in volume at the end of 8 weeks and 96% improvement in area at the end of 12 weeks. Conclusion: This study demonstrates that Autologous PRFM is a safe and efficacious method for the treatment of non-healing ulcer and at the same time simple and highly cost effective method.","PeriodicalId":281715,"journal":{"name":"Journal of Clinical and Cosmetic Dermatology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126222335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}