International Journal of Pharma Medicine and Biological Sciences最新文献

{"title":"Two-Dimensional DICOM Feature Points and Their Mapping Extraction for Identifying Brain Shifts","authors":"H. Noborio, Shota Uchibori, M. Koeda, Kaoru Watanabe","doi":"10.18178/IJPMBS.8.3.71-78","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.3.71-78","url":null,"abstract":"In order to model organ deformation precisely, we extract numerous feature points and also their mapping correspondences from two layered two-dimensional Digital Imaging and Communications in Medicine (DICOM) images. In this study, we first selected the same image twice (the 68th image) from 124 layered two-dimensional DICOM images, and then two consecutive images (the 68th and 69th) and two that were far apart (the 55th and 80th). Next, twodimensional feature points were extracted from these images, and their mapping was searched. We utilized the two-dimensional image feature point extraction/correspondence algorithms scale-invariant feature transform (SIFT), KAZE, Accelerated KAZE (AKAZE), and oriented FAST and rotated BRIEF (ORB) from OpenCV with real DICOM files to confirm that the aforementioned extraction and mapping was possible. According to our results, although the method for searching for matches by only looking for similar feature points in the vicinity of a certain feature point required slightly more calculation time than the method of looking for matches across the entire DICOM area, in the end it did decrease the number of mistaken matching correspondences.","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"1964 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129657827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Instructional Media Human Anatomy and Physiology Using Virtual Reality","authors":"Janejira Euasukaree, S. Visitsattapongse","doi":"10.18178/IJPMBS.8.3.96-99","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.3.96-99","url":null,"abstract":"","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114924729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Habits and Biological Clocks Determined in Children: Cognitive Fluctuations and Intelligence","authors":"S. Figueiredo, O. Nunes, J. Hipólito, C. Tomás","doi":"10.18178/IJPMBS.8.3.114-117","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.3.114-117","url":null,"abstract":"","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132566585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Age, Working Period and Work Duration with Fatigue on Pedycab Drivers in North Kotamobagu District, North Sulawesi Indonesia","authors":"Bongakaraeng Bongakaraeng, Semuel Layuk, Ellen Pesak, Maryam Danial","doi":"10.18178/IJPMBS.8.3.91-95","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.3.91-95","url":null,"abstract":"","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129719919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finite Element Analysis Evaluating Function of LCP System for Osteoporotic Humerus Fracture","authors":"Jung-Soo Lee","doi":"10.18178/IJPMBS.8.3.86-90","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.3.86-90","url":null,"abstract":"In this study, we developed a 3 parts fracture model of osteoporotic humerus by reconstructing the four structures of the humerus (cortical bone, trabecular bone, articular cartilage, sub-chondral) using a CT image for 3D CAD modeling. 3D CAD modeling of the fractured humerus and locking compression plate (LCP) system were done with the use of SolidWorks 2017. Finite element analysis (FEA) of the osteoporotic humerus 3 parts fracture, LCP system was analyzed by ANSYS Workbench 19.0, and the stress such as Maximum shear stresses on locking screw-cortical bone interface area, Maximum von Mises stresses at LCP and LCP-locking screw assembly was obtained with FEA. In torsion force applied load condition, the stress occurred in with calcar screw was 50% to 200% lesser than without calcar screw, effect of calcar screws was confirmed.","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124577640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Red Bean (Vigna angularis [Willd] Ohwi & Ohashi) Extract Administration on Lipid Profile, Uric Acid, and Blood Glucose Level in Male White Rat","authors":"Benedicta I. Rumagit, Isworo Isworo, D. E. Kalonio","doi":"10.18178/IJPMBS.8.3.110-113","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.3.110-113","url":null,"abstract":"","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125268950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Short-Term Blood Glucose Prediction Algorithms","authors":"E. L. Litinskaia, P. Rudenko, K. V. Pozhar, N. Bazaev","doi":"10.18178/IJPMBS.8.2.34-39","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.2.34-39","url":null,"abstract":"It has been about 60 years since Watson and Crick first discovered the double-helix structure of DNA. Each genome (about 3 billion long) define every human uniquely (e.g. hair colour, eye colour, etc.) as well as one's genetic diseases. Consequently, there is a need to find the genome of each individual for assessing the genetic risk of potential diseases. At the same time, research groups are sequencing the DNA of all kinds of organisms, e.g., the rice genome in search of higher production yields, the bacteria genome in search of a more effective cure, and the orchid genome in search of more varieties and higher financial returns. To sequence a genome, Next-Generation Sequencing (NGS) technology is commonly used to output billions of overlapping DNA fragments (known as reads) from the genome, but without information on how these reads link together to form the genome. Then, effective sequencing software tools are used to combine these reads to form the genome. This process is called \"genome assembly\".Theoretically, genome assembly is an easy task as the chance of mis-matching two reads is extremely low if they overlap 30-40 positions (because of 4^30 >>> 3x10^9). In this talk, we shall review past developments and difficulties of genome assembly and explain why some of the straightforward approaches fail. The most successful and counter-intuitive approach which breaks the reads into smaller parts before assembly will be introduced. Our recent work to develop more efficient algorithms and software tools for genome assembly will also be discussed. 2018 CBEES-BBS TIANJIN, CHINA CONFERENCE 13 Keynote Speaker III Prof. Ming Chen Zhejiang University, China Prof. Ming Chen received his PhD in Bioinformatics from Bielefeld University, Germany, in 2004. Currently he is working as a full Professor in Bioinformatics at College of Life Sciences, Zhejiang University. His group research work mainly focuses on the systems biology, computational and functional analysis of non-coding RNAs, and bioinformatics research and application for life sciences. Prof. Chen is serving as an academic leader in Bioinformatics at Zhejiang University. He chairs the Bioinformatics society of Zhejiang Province, China. He is a committee member of Chinese societies for \"Modeling and Simulation of Biological Systems\", \"Computational Systems Biology\", \"Functional Genomics & Systems Biology\" and \"Biomedical Information Technology\". Topic: ―Non-Coding RNAs and their Versatile Interactions)‖ Abstract—Advances in RNA sequencing technologies and computational methodologies have provided a huge impetus to non-coding RNA (ncRNA) study. Previously we developed miRNA target prediction/identification approaches and constructed comprehensive miRNAand miRNA*mediated regulatory networks. In this talk, we provide an overview of ncRNA repertoire and highlight recent discoveries of their versatile interactions. Several ncRNA regulatory network studies are introduced: 1.) the effect of 3D architectur","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115789170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatoprotective Effects of Novel Cultivated Antrodia cinnamomea","authors":"H. Hsiao, Y. Weng","doi":"10.18178/IJPMBS.8.2.65-70","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.2.65-70","url":null,"abstract":"","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114671018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Docking of Mycosporine-Like Amino Acid Analogs in Neuroreceptors – GABAA, GABAB, DRD1, 5-HT3, and nAChR as Potential Drug Candidate for Neuropharmacology","authors":"Keene Louise D. L. Topacio, L. Tayo, A. Magpantay, A. P. Adornado","doi":"10.18178/IJPMBS.8.2.58-64","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.2.58-64","url":null,"abstract":"The objective of this study is to identify and assess the Mycosporine-like Amino Acid (MAA) analogs binding properties with GABA Type A Receptor-Associated Protein (GABARAP), Dopamine Receptor D1 (DRD1), GABAB, 5Hydroxytryptamine Type 3 (5-HT3) and Nicotinic Acetylcholine Receptor (nAChR) through molecular docking using Accelrys Discovery Studio 2.5 as potential drug candidate for neuropharmacology. The microwave promoted synthesized MAA-analogs adapted from the work of Andreguetti et al. and the protein receptors gathered through RCSB Protein Data Bank were prepared, defined, and simulated using a molecular docking software implemented with docking algorithms and receptor-ligand interactions protocols to calculate the binding and entropic energies of the docked ligand unto protein receptors. The MAA-cyst and other MAA-analogs were found to be compatible, favorable, thermodynamically spontaneous, and novel ligand as candidate drugs for the receptor, GABARAP based on the calculated binding and entropic energy values. Competitions and specificity have been observed when same analogs were docked unto a receptor having a specific ligand based on the magnitudes of the negative binding energy values. With the use of molecular docking software, the screening and discovery of potential drug candidate for various neuropharmacological disorders have become faster, easier, and relatively low-cost since not everything can be proved experimentally as traditional experimental methods for drug discovery takes a long time.","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131810743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Numerical Evaluation of the Performance Efficiency of Small-Caliber Colonoscopes in Reducing Patient Pain during a Colonoscopy: Influence of Gender","authors":"Xuehuan He, Jing Bai, Debao Zhou","doi":"10.18178/IJPMBS.8.2.28-33","DOIUrl":"https://doi.org/10.18178/IJPMBS.8.2.28-33","url":null,"abstract":"","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"456 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122165173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}