Colloids and Surfaces A: Physicochemical and Engineering Aspects最新文献

{"title":"Superelastic, ultralight, superhydrophobic bacterial cellulose aerogel for efficient absorption of oil from water","authors":"Hui Cao ,&nbsp;Yuming Zhang ,&nbsp;Yi Fang ,&nbsp;Cong Xue ,&nbsp;Ruifeng Ran ,&nbsp;Haofei Nie ,&nbsp;Yanxiang Li ,&nbsp;Wangliang Li","doi":"10.1016/j.colsurfa.2025.136294","DOIUrl":"10.1016/j.colsurfa.2025.136294","url":null,"abstract":"<div><div>The development of green, efficient and reusable absorption materials remains a challenge in the field of oil-water separation. Herein, a superhydrophobic bacterial nanocellulose (BC)-based aerogel (s-BPGA) was developed using directed freeze-drying method, followed by modification through chemical vapor deposition (CVD). Polyethyleneimine (PEI) and γ-glycidoxypropyltrimethoxysilane (GPTMS) was used as crosslinkers to enhanced the mechanical strength of s-BPGA. The prepared aerogel had low density (5.8 mg⸱cm^–3) and robust mechanical strength with almost 100 % shape recovery after 90 % compression strain, and it showed excellent absorption to <em>n</em>-hexane, aviation kerosene and tetrachloromethane and other oils and organic solvents. The absorption capacity of s-BPGA aerogel was in the range of 80.91 (<em>n</em>-hexane)-203.30 (tetrachloromethane) g⸱g⁻¹. After undergoing 20 absorption-desorption cycles by simple mechanical extrusion method, it almost retained its original shape and absorption capacity, demonstrating remarkable recyclability.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136294"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low temperature adsorption of nitrate in water by ammoniac-grafted iron-based biochar: Electrostatic interaction and surface complexation","authors":"Meijie Yan,&nbsp;Qi Zhu,&nbsp;Jiatong Zhen","doi":"10.1016/j.colsurfa.2025.136313","DOIUrl":"10.1016/j.colsurfa.2025.136313","url":null,"abstract":"<div><div>Since organic matter and ammonia in wastewater have been effectively controlled in recent years, nitrate nitrogen has progressively emerged as one of the most important yet challenging to measure markers of water quality. Scientists are trying to create materials for water treatment that are safe, affordable, and efficient. In order to create the new adsorbent Fe-TBC, maize stover charcoal (BC) was impregnated with ferric chloride and subsequently grafted with triethylamine. The findings demonstrated that the ammonia grafting produced a greater positive charge, the iron impregnation expanded the surface area of BC, and the charcoal fibers exhibited a rich pore structure. Numerous characterization analyses verified the effective synthesis of Fe-TBC, and experimental demonstration and characterization studies delved into the adsorption mechanism of Fe-TBC on nitrate. Fe-TBC's adsorption rate on nitrate was enhanced, and it continued to have a superior adsorption impact at lower temperatures, according to adsorption kinetics and isotherm investigations. When the concentration of interfering ions is the same, the removal efficiency of nitrate by Fe-TBC decreased by less than 20 %. These findings indicate that Fe-TBC is a new type of environmentally friendly low temperature selective adsorbent with high application value.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"710 ","pages":"Article 136313"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143152914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of magnetic fluids based on La0.80Ag0.15MnO3-δ nanoparticles","authors":"Martin Kovalik ,&nbsp;Alena Juríková ,&nbsp;Martina Kubovčíková ,&nbsp;Matúš Mihalik ,&nbsp;Mária Zentková ,&nbsp;Matej Baláž ,&nbsp;Jaroslav Briančin ,&nbsp;Zdenka Lukáčová Bujňáková ,&nbsp;Martin Vavra ,&nbsp;Maksym Lisnichuk ,&nbsp;Martin Majerník ,&nbsp;Marko Bošković ,&nbsp;Marija Perović ,&nbsp;Rastislav Jendželovský ,&nbsp;Josef Polčák ,&nbsp;Marian Mihalik","doi":"10.1016/j.colsurfa.2025.136300","DOIUrl":"10.1016/j.colsurfa.2025.136300","url":null,"abstract":"<div><div>Water-based magnetic fluids were prepared using La_0.80Ag_0.15MnO_{3-<em>δ</em>} magnetic carriers with the maximal Curie temperature <em>T</em>_C = 319.5 K (46.4 °C). The starting nanoparticles mainly consisted from agglomerates with average particle size between 43 and 47 nm. Separation of nanoparticles from aggregates using a stirred ball mill in combination with the use of anionic sodium dodecyl sulphate surfactant led to the preparation of electrostatically stabilised magnetic fluid with average hydrodynamic size of particles <em>x</em>_av less than 75 nm. A combination of mechanical grinding, sonication and etching in different acids was used to prepare Dextran 40 kDa sterically and carboxymethyl-dextran 15 kDa electrosterically stabilised magnetic fluid with average hydrodynamic size of particles ranging between 50 and 190 nm. Milling and etching results in reduction of <em>T</em>_C of about 3 K, etching causes a drastic decrease in saturation magnetization, but the magnetocaloric properties are unaffected by the preparation of the magnetic fluid, only the magnetic entropy change is reduced by three orders of magnitude. Magnetic carrier has the potential to reach the desired magnetic heating temperature <em>T</em> = 43.6 °C for applications in hyperthermia and magnetic fluids are capable to reach <em>T</em> = 38.1 °C by magnetic heating. The maximal specific absorption rate of magnetic carrier <em>SAR</em> = 134.7 W/g and in the case of magnetic fluid <em>SAR</em> = 41.9 W/g. The synthesized nanoparticles and the prepared magnetic fluids may represent materials with potential in cancer treatment, as the most pronounced effect was observed in the case of lung cancer cell line A549. Analysed nanoparticles induced a decrease in metabolic activity even at relatively low concentrations.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136300"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143376935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bamboo nanocellulose derived carbon loaded bismuth oxide: An effective nanocomposite for the solar photocatalytic degradation of malachite green","authors":"Dongbin Yang ,&nbsp;Longbin Li ,&nbsp;Wen Xu ,&nbsp;Zhaoping Jia ,&nbsp;Jiandu Lei ,&nbsp;Jing Liu","doi":"10.1016/j.colsurfa.2025.136315","DOIUrl":"10.1016/j.colsurfa.2025.136315","url":null,"abstract":"<div><div>Multi-component structural composites to tune the energy band structure of photocatalysts can achieve higher activity. In this study, flaky CNFC@Bi₂O₃ composites with high dispersibility were synthesised by a one-step calcination method using CNF as a template. The morphology and composition of the materials were characterized by SEM, XPS, XRD, PL, UV–vis DRS, TOC and LC-MS. The abundance of functional groups on the surface of the CNF-derived carbon induces the formation of this morphology, and the composite forms a direct Z-type heterojunction with good response in the visible region. The degradation of malachite green dye under visible light irradiation at 465 nm was found to be 758.64 mg g⁻¹ in 5 h. There was a significant increase in the degradation of malachite green dye compared to the composite BC@Bi₂O₃ prepared with bamboo cellulose(BC) as a template (425.76 mg g⁻¹). The findings indicated that CNFC@Bi₂O₃ dye removal exhibited the highest level of efficacy in comparison to CNF/0.3Bi (473.04 mg g⁻¹) and CNF/1.7Bi (545.52 mg g⁻¹). The best degradation of malachite green was found to occur in a weakly alkaline environment, with the order of effect of free radicals being: h⁺ &gt; ·OH&gt; ·O₂^-. The results indicate that the CNFC@Bi₂O₃ composites have great potential for dye wastewater degradation and environmental remediation, and provide a new idea for the synthesis of sustainable, eco-friendly and high performance photocatalysts.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136315"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suppressed Mn dissolution behavior to improve cycling performance of Cr-modified Li1-xMn2O4 electrodes","authors":"MengJun Zhang ,&nbsp;Chao Sun ,&nbsp;JiangYao Li ,&nbsp;ChengLong Shi ,&nbsp;Xiumin Li ,&nbsp;Bing Zhao","doi":"10.1016/j.colsurfa.2025.136283","DOIUrl":"10.1016/j.colsurfa.2025.136283","url":null,"abstract":"<div><div>Stably and efficiently extracting lithium from brine sources is critical for addressing pressing energy and environmental challenges. LiMn₂O₄ electrodes are widely used in electrochemical lithium recovery systems due to their effectiveness in lithium extraction. However, their limited extraction capacity and insufficient stability hinder their practical application. To overcome these challenges, we synthesized a series of Cr-modified LiMn₂O₄ (111) crystal plane materials, driven by the understanding that the multi-electron nature of Cr could improve stability without compromising lithium adsorption capacity. Indeed, the Cr-modified LiMn₂O₄ showed significantly enhanced performance, including reduced Mn dissolution (3.73 %), lower resistance, and better stability compared to the unmodified LiMn₂O₄ (1.38 %). The experimental results demonstrated that Cr doping successfully enhanced the material's stability, and theoretical calculations further confirmed that Cr incorporation enhances the electrode's lithium adsorption ability, as evidenced by the more negative adsorption energy for Li(H₂O)₄⁺ (–3.52 eV for Mn₂O₄ vs. –4.09 eV for Cr_1.0Mn_1.0O₄), thereby improving its overall adsorption performance. LiCr_1.0Mn_1.0O₄, with an expanded lattice constant, demonstrated a higher Li⁺ diffusion coefficient (6.90*10⁻¹¹) and lower intercalation energy, as verified by cyclic voltammetry. In hybrid capacitive deionization (CDI) experiments, LiCr_1.0Mn_1.0O₄ showed a minimal Mn dissolution loss of only 1.37 %, while maintaining a Li⁺ intercalation capacity of 21.51 mg/g. These findings highlight the potential of Cr modification on the (111) facets of LiMn₂O₄ as an effective strategy to enhance electrochemical lithium extraction performance, providing a promising approach for efficient lithium recovery in practical applications.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"710 ","pages":"Article 136283"},"PeriodicalIF":4.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143152918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-step surface modification of small molecule taurine for the preparation of high-performance reverse osmosis membranes","authors":"Bangzhen Liu ,&nbsp;Fuhao Zhang ,&nbsp;Zicheng Wang ,&nbsp;Tengfang Zhang ,&nbsp;Xun Zhou ,&nbsp;Yuhao Chen ,&nbsp;Haixiang Sun","doi":"10.1016/j.colsurfa.2025.136314","DOIUrl":"10.1016/j.colsurfa.2025.136314","url":null,"abstract":"<div><h3>Hypothesis</h3><div>Surface modification is a prevalent method for reverse osmosis (RO) membranes to enhance the separation performance due to its advantageous characteristics, including stability and ease of integration. However, the macromolecules utilized in modification processes often need intricate procedures.</div></div><div><h3>Experiments</h3><div>In this work, the micromolecule taurine (TAU) was grafted onto RO membrane surface through a simple one-step covalent grafting modification. The mechanism of TAU modification was revealed through the characterization of morphology and structure of the membranes as well as the analysis of performance tests.</div></div><div><h3>Findings</h3><div>The molecular chain flexibility of the modified membrane was enhanced, which was conducive to the permeation performance. In addition, sulfonic acid groups were introduced onto the membrane surface with the objective of improving hydrophilicity, electronegativity and chelation with boric acid. The optimal modified membranes showed an enhancement of flux by over 40 % while maintaining the salt rejection rate. Furthermore, the modified membranes demonstrated lower flux decline rates in bovine serum albumin and dextran pollutants tests, indicating an enhancement in the membrane's fouling resistance. In addition, the modified membranes exhibited enhanced boron rejection properties. The one-step surface grafting modification strategy provides an effective method to improve the boron rejection capacity and fouling resistance of RO membranes.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136314"},"PeriodicalIF":4.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modelling and simulation of surface-tension-dominant two-phase flows with an improved geometric volume of fluid framework","authors":"Huihuang Xia ,&nbsp;Wei Ge","doi":"10.1016/j.colsurfa.2025.136277","DOIUrl":"10.1016/j.colsurfa.2025.136277","url":null,"abstract":"<div><div>Two-phase flows with surface tension are ubiquitous in engineering applications. A high-fidelity numerical framework for capturing sharp interfaces and eliminating unphysical spurious currents is of great significance. To this end, an improved geometric VoF framework combining a numerical filtering approach to accurately calculate surface tension and effectively suppress spurious currents has been presented. Unlike traditional algebraic VoF approaches, our framework accurately captures sharp interfaces without any interface diffusion. Our improved numerical framework is implemented in the open-source C++ library OpenFOAM. Both two- and three-dimensional numerical benchmark cases are conducted to demonstrate the performance of our framework in suppressing spurious currents. Our framework shows the most superior performance when comparing against numerical results of two geometric VoF solvers, namely interIsoFoam and interFlow. Droplet spreading on a wall is employed to evaluate the performance of our framework in maintaining pre-specified contact angles on both hydrophilic and hydrophobic walls. Rayleigh–Taylor instability benchmark case shows the capability of our framework in capturing sharp interfaces for both cases with and without surface tension. Buoyancy-driven bubble rising simulations demonstrate improved accuracy in predicting bubble rising velocity without numerical oscillations. Furthermore, our model and numerical method are utilized to investigate the surface-tension-dominant droplet coalescence. Numerical results demonstrate the promising capability of our enhanced framework in predicting droplet spreading and coalescence dynamics.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136277"},"PeriodicalIF":4.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probing the antifouling mechanism of the oil-water separation membranes with ZnO nanostructures","authors":"Yue Feng ,&nbsp;Xun Liu ,&nbsp;Jingyi Wang ,&nbsp;Xinyu Zou ,&nbsp;Dianlin Wang ,&nbsp;Lei Xie","doi":"10.1016/j.colsurfa.2025.136312","DOIUrl":"10.1016/j.colsurfa.2025.136312","url":null,"abstract":"<div><div>Nanostructures have been commonly incorporated into oil-water separation membranes to improve their antifouling properties. However, the antifouling mechanism of the membrane with different nanostructures is still unclear. In this work, ZnO nanostructures, i.e., nanorods, hollow nanorods and randomly assemble nanosheets, were constructed on polyvinylidene fluoride (PVDF) membrane surfaces. The resulted membranes exhibited improved antifouling properties in comparison with the pristine PVDF membrane, and the hollow nanorods showed the best antifouling property. The antifouling mechanism was investigated through direct force measurements between oil drops and membrane surfaces using atomic force microscopy. The theoretical analysis of approach force curves indicated that the repulsive electrical double layer force was enhanced at higher pH and in the presence of ZnO nanostructures, which prevented the oil attachment on the membrane surface. The retraction force curves suggested that the adhesion between oil and membrane was significantly affected by the ZnO nanostructures, and the adhesion followed the trend of hollow nanorods &lt; randomly assemble nanosheets &lt; nanorods. Consequently, the oil drops on the membrane with hollow nanorods could be easily removed by water rinsing, which agreed with the flux recovery results. This work provided a fundamental understanding of the antifouling mechanism of the oil-water separation membranes with nanostructures, and a useful guidance for constructing suitable surface structures for efficient oil-water separation membranes.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136312"},"PeriodicalIF":4.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143219525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spartina alterniflora biochar coupled BiOBr with dominant exposed facet and oxygen vacancies for efficiently photocatalytic degradation of ciprofloxacin","authors":"Peng Ju ,&nbsp;Shuo Yu ,&nbsp;Guojia Zhang ,&nbsp;Hongyu Mou ,&nbsp;Jun Wang ,&nbsp;Yingchao Li ,&nbsp;Shiyao Lu ,&nbsp;Jianchao Sun","doi":"10.1016/j.colsurfa.2025.136306","DOIUrl":"10.1016/j.colsurfa.2025.136306","url":null,"abstract":"<div><div>Addressing water pollution caused from the misuse of ciprofloxacin (CIP) is an urgent issue. In this study, <em>Spartina alterniflora</em> biochar coupled BiOBr (BC@BiOBr) composites were hydrothermally synthesized to achieve a synergistic effect of adsorption-coupled photocatalytic oxidation. In the BC@BiOBr composites, BiOBr microspheres grew <em>in-situ</em> on the surface of <em>Spartina alterniflora</em> biochar, forming the layered structure assembled by many nanosheets. Among the obtained products, when the mass fraction of BC was 20%, BC@BiOBr-2 exhibited the best photocatalytic performance and superior stability towards the degradation of CIP, achieving a 100% degradation efficiency within 90 min. The introduction of BC not only elevated the adsorption ability and increased the active reaction sites, but also narrowed the band gap and enhanced the visible light response range of BiOBr, accompanied by the rich oxygen vacancies and dominant exposed (102) facet of BiOBr, synergistically improving the photocatalytic activity greatly. The photocatalytic mechanism was speculated according to the tests of electron paramagnetic resonance and radical quenching experiments, proving the predominant roles of ·O₂^- and ·OH during the photocatalytic process. Overall, this work provides a feasible strategy for enhancing the photocatalytic performance of BiOBr while promoting the high-value reuse of the invasive species <em>Spartina alterniflora</em>.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136306"},"PeriodicalIF":4.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143219155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peptide conjugated nintedanib loaded graphene quantum dots: Characterization and cell based studies","authors":"Vrushti Kansara,&nbsp;Mitali Patel","doi":"10.1016/j.colsurfa.2025.136298","DOIUrl":"10.1016/j.colsurfa.2025.136298","url":null,"abstract":"<div><div>The present study is aimed to develop the nitrogen doped graphene quantum dots (N-GQDs) based nanocarrier to target epidermal growth factor receptor (EGFR) in the treatment of non-small cell lung cancer (NSCLC). The N-GQDs were functionalized with GE11 peptide (a targeting agent) with high affinity for EGFR (GE11-N-GQDs), using carbodiimide chemistry. The studies revealed that the particle size of the N-GQDs increased to 96.88 ± 2.16 nm after NE loading (NE-N-GQDs). The GE11 functionalization and NE loading (GE11-NE-N-GQDs) further increased the particle size to 124.0 ± 1.76 nm. The particle shape of the GE11-NE-N-GQDs were cubic and quasi-hexagonal. The reduction in the crystallinity was evident by the selected area electron diffraction (SAED) pattern. The GE11-NE-N-GQDs showed higher drug loading (97.42 ± 1.15 %) and entrapment efficiency (98.14 ± 1.32 %) than the NE-N-GQDs (97.38 ± 1.46 %, 92.36 ± 1.68 %). The N-GQDs based nanocarriers displayed good antioxidant activity and hemocompatibility. The GE11-NE-N-GQDs displayed pH dependent and prolonged release (99.78 ± 2.20 %) at 50 h. The %cell viability of the GE11-NE-N-GQDs treated A549 (human lung adenocarcinoma) cells was less (IC₅₀: 1 µg/ml) than the NE-N-GQDs (IC₅₀: 3 µg/ml) and free NE (IC₅₀: 6.60 µg/ml). The GE11-N-GQDs enhanced intracellular uptake and arrested G1 phase which increased apoptosis and number of cells in sub-G1 phase. Hence, the results showed the GE11-N-GQDs as a promising approach to target EGFR overexpression in NSCLC.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"711 ","pages":"Article 136298"},"PeriodicalIF":4.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}