One Health & Risk Management最新文献

{"title":"Evaluation of costs related to antimicrobial resistance of priority Gram-negative bacilli","authors":"Maria Anton, Larisa Pantea, Olga Burduniuc, Marcela Chilianu, V. Bucov, Livia Tapu","doi":"10.38045/ohrm.2024.1.06","DOIUrl":"https://doi.org/10.38045/ohrm.2024.1.06","url":null,"abstract":"Introduction. Antimicrobial Resistance (AMR) is one of the most serious threats to global public health, causing over 700 thousand deaths annually. In addition to the social burden, AMR generates high medical costs, and estimating these at the hospital level has been the subject of research in many international studies. \u0000Material and methods. A comprehensive study was conducted, encompassing 172 cases of invasive infections recorded in patients hospitalized at the “Timofei Mosneaga” Republican Clinical Hospital, from which strains of antimicrobial-resistant E. coli, K. pneumoniae, A. baumannii, and P. aeruginosa were isolated in the years 2019-2021. Based on data regarding the duration of hospitalization, treatment costs, and expenses for investigations, indicators such as average cost, the median, minimum and maximum values of treatment, including the cost of antibiotics and laboratory analyses, were calculated. \u0000Results. The economic impact indicators of AMR at the hospital level include: the duration of hospitalization, the total costs of a treated case, the costs of antibiotics, and the costs of laboratory analyses. In the structure of microorganisms isolated from the patients included in the study, K. pneumoniae predominates, accounting for 44.2%, and the total treatment cost for this organism was the highest at 202731.5 dollars. The maximum duration of hospitalization was recorded in patients from whom A. baumannii was isolated (27.7 days). \u0000Conclusions. The resistance of strains isolated from patients has directly contributed to the extension of the hospitalization period. The resistance of A. baumannii and K. pneumoniae species has predominantly led to the increase in the economic burden of AMR.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"70 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140495724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric analysis of research relating to noise pollution reported over the period 2001–2020","authors":"Erhan Kaya, Musa Şahin, O. Açar","doi":"10.38045/ohrm.2023.4.05","DOIUrl":"https://doi.org/10.38045/ohrm.2023.4.05","url":null,"abstract":"Introduction In the new globalized world, noise pollution has started to become a public health problem. We searched for publications about noise pollution in our study. In our study, we examined the noise pollution articles in the Web of Science (WoS) database. \u0000Material and Methods A total of 2722 papers were identified which were published between 2001 and 2020, finally, 1815 articles were analyzed. VOSviewer (version 1.6.11) tool used for bibliometric web visualizations. \u0000Results When trend analysis was applied to the number of articles by years, a statistically significant increase was detected. The United States contributed the most publications. The countries with the most articles per million population were determined to be Scotland, Singapore, and Ireland, respectively. Most articles on noise pollution were published in the journal Applied Acoustics. The three most used keywords are “noise pollution”, “noise” and “traffic noise”. \u0000Conclusions This study showed that there has been a trend of an increasing number of articles on noise pollution in recent years. Also it can be considered that this bibliometric study will help identify gaps in the current research data. \u0000 ","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121143367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of infections, recoveries and deaths from COVID-19 in rivers state, Nigeria","authors":"O. Adedire, Walter C. Jonh, Afolabi OLA OOLADEJO, G. Onuwa, Jacob JEPTHAH MBAH","doi":"10.38045/ohrm.2023.4.04","DOIUrl":"https://doi.org/10.38045/ohrm.2023.4.04","url":null,"abstract":"Introduction: While some patients recovered, others died across the world thereby losing their loved ones. The objective of the current study is to determine statistical difference in means of COVID-19 infected population (laboratory confirmed), discharged cases(recovered) and deaths resulting from COVID-19 pandemic in Rivers State, Nigeria. \u0000Material and Methods: In this study, extraction of infected population (laboratory confirmed), discharged cases and deaths from COVID-19 was carried out from data obtained from Nigeria Centre for Disease Control which covered a period of 572 days (25th March 2020 - 17th  October  2021). The test for significance of means among the variables was done using one-way Analysis of Variance (ANOVA) followed by Tukey HSD test. The two variables whose means do not significantly differ were tested for strength of relationship and dependence using correlation analysis and cubic polynomial function respectively. \u0000Results: Results showed  that there is statistically significant difference between infected population, discharged cases and deaths from COVID-19 as obtained from one-way ANOVA (F(2, 1710) = 121.958, p = 0.000). Use of Tukey HSD test indicated that means of infected population and discharged cases do not differ from each other (p>0.01); however, mean deaths from COVID-19 significantly differ from others at 99%  confidence intervals (p<0.01). There was weak positive relationship between deaths due to COVID-19 and  other  two groups (r=0.360, n=571, p=0.000).  However, moderate positive correlation existed between COVID-19 infected population and discharged population (r=0. 566, n=571, p=0.000) at  99% confidence interval. \u0000Conclusions: Mean of deaths from the study population was significantly different from means from both infected population and discharged (recovered) cases. This implies that only few people died from COVID-19  in Rivers State Nigeria when compared to  those who got infected and recovered from COVID-19 pandemic.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133232918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A reduced fixed dose of Tocilizumab 200 mg compared to 400 mg in patients with severe COVID-19 disease","authors":"Stela Cojocaru, I. Russu, Galina Buta, Sebastian Bersan, Valentina POTÎNG-RAȘCOV, Natalia Culiuc, Lilia Baba","doi":"10.38045/ohrm.2023.4.02","DOIUrl":"https://doi.org/10.38045/ohrm.2023.4.02","url":null,"abstract":"Introduction. The deregulated excessive pro-inflammatory cytokine secretion have a detrimental impact on the evolution of COVID-19, aggregating the tissue impairment, organ failure, and increasing the risk for death. Several studies have demonstrated the beneficial effect of Tocilizumab (TCZ) in reducing hyperimmune response in severe forms of COVID-19. \u0000Materials and methods. This study is a retrospective cohort consisting of a sample of 66 patients hospitalised with COVID-19. The 1-st group consists of 33 patients treated with TCZ 200 mg IV once, and the 2-nd group – of 33 patients treated with TCZ 400 mg IV once. \u0000Results. The average age of the patients included in the study was 58,22±1,38 years. A decision regarding TCZ administration was made on average on the 11,34±0,31 day of the disease, when the beginning of Cytokine Storm was suspected in the patients already on dexamethasone treatment. The dose of TCZ had significance on the duration of patients' disabilities, duration of oxygen therapy, and duration of hospitalization, with better results for TCZ 400 mg vs. TCZ 200 mg. However, we cannot prove that the dose of TCZ influences the percentage of patients transferred to the ICU for invasive or non-invasive ventilation. \u0000Conclusion. The 200 mg fixed dose of TCZ can be a life-saving option for severely ill patients with COVID-19 in the context of IL-6 inhibitor supply shortages. \u0000Key words: COVID-19, Cytokine Storm, Tocilizumab.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123829748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation, identification and conservation of bacteria of biotechnological interest","authors":"Ludmila Balan","doi":"10.38045/ohrm.2023.4.03","DOIUrl":"https://doi.org/10.38045/ohrm.2023.4.03","url":null,"abstract":"Introduction. The evaluation of microbial biodiversity is an important step in the process of its conservation, and the identification of bacterial strains of biotechnological interest allows their application as support for the development of sustainable agriculture technologies. \u0000Material and methods. From the lakes of the \"La Izvor\" park, 213 types of bacteria, 148 of them pathogenic, were isolated. From the non-pathogenic ones, those of biotechnological interest were determined the enzymatic properties, antimicrobial activity and were identified by molecular biological methods after that preserved by the lyophilization method with the determination of viability before and after lyophilization. \u0000Results. The microbial biodiversity of the \"La Izvor\" lakes was studied, 213 types of bacterial colonies were isolated in pure culture, which of 148 proved to be enteropathogenic belonging to the genera Escherichia, Salmonella, Shigella, Enterobacter and Klebsiella as and other strains from the Enterobacteriaceae family. The purpose of the research consisted in the isolation and identification of non-pathogenic bacteria of biotechnological interest with different properties that could serve to elaborate and improve the development of sustainable agriculture technologies. Nineteen strains with enzymatic properties and high antifungal activity against phytopathogenic fungi, were selected for molecular identification, passported, submitted to the NCNM and preserved by the lyophilization method for determination valuable properties for a long time. \u0000Conclusions. In the lakes of \"La Izvor\" park there is a very large variety of microorganisms, especially bacteria, some of which are enteropathogenic bacteria that can cause diseases in the population. Selected non-pathogenic strains stored in the NCNM can be applied against phytopathogens that cause dangerous disease and damage in agriculture major crops. As a result of lyophilization, we found that all strains showed the osmotic and thermal shocks tolerance and have a viability over 75%. \u0000Key words: microbial biodiversity, isolation, identification, conservation.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122313604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of D-dimers in patients with COVID-19: narrative synthesis","authors":"Natalia Cernei","doi":"10.38045/ohrm.2023.4.01","DOIUrl":"https://doi.org/10.38045/ohrm.2023.4.01","url":null,"abstract":"Introduction. Contemporary researchers have suggested and demonstrated the hypothesis that the elevated level of D-dimers, which is a valuable marker of coagulation and fibrinolysis activation, can predict the severity of COVID-19, pulmonary complications, and thromboembolic events before they occur. \u0000Material and methods. The bibliographic resources were analyzed and selected from databases such as PubMed, Hinari, SpringerLink, and Google Search using keywords such as “COVID-19,” “SARS-CoV-2,” “coronavirus,” “D-dimers,” “biomarkers,” and “severity prediction,” which were used in various combinations to maximize search efficiency. Therefore, the manuscript contains 51 representative articles for the purpose of this synthesis article. \u0000Results. The D-dimer levels are significantly higher in patients with severe forms of COVID-19 compared to those with non-severe forms, in patients with acute respiratory distress syndrome compared to those without acute respiratory distress syndrome, and in deceased patients compared to those who have survived. D-dimers positively correlate with the degree of severity and the increased risk of progression to severe disease, inversely proportional to the survival rate. They can predict prognosis, determine therapeutic strategies, prevent complications, positively influence the disease’s course, and monitor the prognosis. \u0000Conclusions. D-dimers should be used as a pre-radiographic screening tool as early as possible after admission and as an indicator for risk stratification of venous thromboembolism in hospitalized patients with COVID-19. Based on the increase in D-dimer levels, adjusting therapeutic doses of anticoagulants is more beneficial for patients compared to administering prophylactic doses.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127878804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes, and practices of parents regarding the use of electronic devices by preschoolers","authors":"Nadejda Farima, A. Timotin, O. Lozan","doi":"10.38045/ohrm.2023.3.04","DOIUrl":"https://doi.org/10.38045/ohrm.2023.3.04","url":null,"abstract":"Introduction. Abortion causes problems in reproductive health, relationships in a couple, psychological and social consequences. A woman's decision to have an abortion depends on many factors, whereas in low-income countries, abortion is viewed as a method of family planning. \u0000Material and methods. A descriptive, quantitative and qualitative sample study was conducted in the Republic of Moldova from December 2021 to February 2022 to identify and evaluate the factors influencing a woman’s decision-making to terminate a pregnancy, as well as to develop recommendations for reducing the number of abortions on demand. The quantitative assessment included a survey carried out on a sample of 399 women who underwent abortions on demand. The qualitative study involved three focus group meetings, where the obstetrician-gynecologists shared their ideas upon the factors determining a woman's decision to terminate a pregnancy. \u0000Results. Analyzing the data obtained, the present research identified the following factors that determined the decision-making of women to terminate a pregnancy: (i) lack of support and disturbed psycho-emotional state in  women; (ii) social and economic problems, particularly, poverty; (iii) study/career-related conditions; (iv) age; e) difficult relationship with  the partner, particularly, domestic violence; (v) fear of COVID-19 infection. \u0000Conclusions. Women's reasons for seeking abortions are complex, traced out by circumstantial and systemic realities.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124532572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors determining on-demand abortion decision-making in women","authors":"Viorelia Grosu, Corina Cardaniuc, Adriana Paladi","doi":"10.38045/ohrm.2023.3.05","DOIUrl":"https://doi.org/10.38045/ohrm.2023.3.05","url":null,"abstract":"Introduction. Abortion causes problems in reproductive health, relationships in a couple, psychological and social consequences. A woman's decision to have an abortion depends on many factors, whereas in low-income countries, abortion is viewed as a method of family planning. \u0000Material and methods. A descriptive, quantitative and qualitative sample study was conducted in the Republic of Moldova from December 2021 to February 2022 to identify and evaluate the factors influencing a woman’s decision-making to terminate a pregnancy, as well as to develop recommendations for reducing the number of abortions on demand. The quantitative assessment included a survey carried out on a sample of 399 women who underwent abortions on demand. The qualitative study involved three focus group meetings, where the obstetrician-gynecologists shared their ideas upon the factors determining a woman's decision to terminate a pregnancy. \u0000Results. Analyzing the data obtained, the present research identified the following factors that determined the decision-making of women to terminate a pregnancy: (i) lack of support and disturbed psycho-emotional state in  women; (ii) social and economic problems, particularly, poverty; (iii) study/career-related conditions; (iv) age; e) difficult relationship with  the partner, particularly, domestic violence; (v) fear of COVID-19 infection. \u0000Conclusions. Women's reasons for seeking abortions are complex, traced out by circumstantial and systemic realities. \u0000 ","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126608300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collaboration of the public health service with primary health care at the territorial level","authors":"Alexandru Cornei, V. Mita, O. Lozan","doi":"10.38045/ohrm.2023.3.08","DOIUrl":"https://doi.org/10.38045/ohrm.2023.3.08","url":null,"abstract":"Introduction. Intrasectoral collaboration in public health represents a huge potential for optimizing the three fundamental public health actions: disease prevention, health protection and healthcare awareness. The COVID-19 pandemic has significantly impacted the engagement of the parties particularly interested in disease prevention and control. \u0000Material and methods. A mixed qualitative and quantitative research (in-depth interviews/questionnaire survey) was carried out within this paper. \u0000Results. Most of the respondents assessed the intrasectoral cooperation as unsatisfactory and consider that the latest reform of the Public Health Service had a negative impact on it.  The pandemic alert caused by the COVID-19 infection served as a catalyst to improve cooperation. The main barriers to collaboration are considered the lack of staff and insufficient communication, various viewpoints and lack of public health knowledge, an overlying complex legal framework and lack of motivation, which often requires central authority involvement. \u0000Conclusions. Some barriers to cooperation can be overcome without any systemic changes and centralized involvement, while more easily achievable measures such as joint training are sufficient. Thus, understanding these aspects can greatly improve the interaction between services.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"26 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125773017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes and practices of the population regarding osteoporosis","authors":"Aurelia Donescu, O. Lozan","doi":"10.38045/ohrm.2023.3.02","DOIUrl":"https://doi.org/10.38045/ohrm.2023.3.02","url":null,"abstract":"Introduction. Introduction. Osteoporosis is a skeletal disease characterized by compromising the mechanical strength of the bone and increasing the risk of fractures. Osteoporosis conditions the increase in illness and disability in the elderly and, respectively, leads to an increase in health expenses. \u0000Material and methods. A cross-sectional descriptive epidemiological study was designed, which included surveying 423 respondents and interviewing representatives of health decision-makers (6 in-depth interviews), during 2020-2022. \u0000Results. In the section on knowledge about osteoporosis, a dissociation of responses was recorded according to the gender criterion – women in 65.4% of cases know better about this problem (χ2=3.898, p=0.273). Knowledge about the fact that osteoporosis can occur during menopause was demonstrated by 45.9% of respondents, of whom women in 76.3% of cases (χ2=36,136,183, p<0.001). The attitude of the respondents was analyzed according to the biological gender. It was found that women show concern about osteoporosis in 63.6% of cases, and men – 35.2%. In the practices chapter, it was found that the respondents consume little milk and cottage cheese, but they usually take calcium food supplements (54%). \u0000Conclusions. Osteoporosis is a current public health problem. Females possess more knowledge about osteoporosis and show a more expressive attitude compared to males.","PeriodicalId":274368,"journal":{"name":"One Health &amp; Risk Management","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115005653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}