One Health & Risk Management最新文献

{"title":"Particularities of respiratory manifestations of COVID-19 infection in children","authors":"S. Şciuca, R. Selevestru, Tatiana Băluțel, C. Conica, Diana ROTARU-COJOCARU","doi":"10.38045/ohrm.2022.3.05","DOIUrl":"https://doi.org/10.38045/ohrm.2022.3.05","url":null,"abstract":"Introduction. COVID-19 infection is common in the pediatric population, presenting a variety of respiratory manifestations and complications. \u0000Material and methods. The study included 64 children from the COVID-19 section, IMSP IMC, with a mean age of 2,04±0,4 years (variations 1 day-17 years), divided into 5 age groups: 0-1 month, 1-12 months, 1-3 years, 3-7 years, >7 years. The methodology of the study is expected to assess the significance of clinical manifestations in the COVID-19 infection episode. \u0000Results. With 21 cases, this study discovered a higher frequency of the disease in infants. The nosological expression of the infection was dominated by pneumonia and unique cases of infection in four children with upper respiratory infections. Every evolution was presented by 11 children, the moderate form being the dominant one. An almost constant sign in the children in the study was a febrile syndrome, which in 31 cases was > 38,0oC. Every second child showed catarrhal respiratory signs, cough, and cyanosis in 66,1% of the children, chest circulation in 32,1% of the cases, wheezing in 6. COVID-19 infection in hospitalized children resulted in respiratory complications in 81,3% of cases and toxic infections – 23,4%. \u0000Conclusions. COVID-19 infection in hospitalized children occurs mainly with pneumonia and only in unique cases of nasopharyngitis, with the constant presence of catarrhal respiratory signs, dyspnea, and fever, but also a susceptibility to develop severe forms and complications.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132545799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the viability of yeast strains after 15 years of conservation","authors":"T. Sirbu, V. Slanina","doi":"10.38045/ohrm.2022.3.03","DOIUrl":"https://doi.org/10.38045/ohrm.2022.3.03","url":null,"abstract":"Introducere. Păstrarea durabilă şi eficientă a microorganismelor în colecții depinde de selectarea corectă a metodei de conservare, parametrilor şi mediilor de protecţie. \u0000Material și metode. A fost evaluată viabilitatea și stabilitatea particularităților morfo-culturale a drojdiilor din CNMN, păstrate sub un strat de ulei de vazelină și în stare liofilizată timp de 15 ani. \u0000Rezultate. Studiul viabilității a 17 tulpini de drojdii din CNMN, după 15 ani de depozitare prin metodele: liofilizare și sub un strat de ulei de vazelină, a demonstrat că, viabilitatea și stabilitatea acestora variază în dependență de gen. Astfel, viabilitatea tulpinilor liofilizate, din genul Rhodotorula a variat în limitele 47,0-65,7%, din genul Saccharomyces – 46,4-58,8%, iar din genul Lipomyces – 64,0-77,8%, comparativ cu viabilitatea înregistrată după liofilizare. De asemenea, s-a stabilit că toate tulpinile de drojdii, păstrate sub uleit de vazelină, sunt viabile, dar prezintă unele modificări ale particularităților morfo-culturale. Astfel, la tulpinile din genul Rhodotorula și genul Saccharomyces,  inoculate pe medii agarizate, coloniile în primul pasaj erau foarte mici, culoarea diferită de cea inițială. La tulpinile din genul Lipomyces astfel de modificări nu au fost depistate. S-a demonstrat că, particularitățile morfo-culturale inițiale se restabilesc mai repede, dacă culturile, păstrate sub ulei, sunt inoculate în malț lichid, apoi efectuate 2-3 pasaje consecutive pe medii agarizate. \u0000Concluzii. Metodele de conservare a tulpinilor de drojdii în stare liofilizată sau sub un strat de ulei de vazelină, sunt foarte eficiente și de perspectivă, asigurând o viabilitate și stabilitate înaltă.   \u0000Cuvinte cheie: tulpini de drojdii, gen, viabilitate, liofilizare, revitalizare, ulei de vazelină.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127216674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syntropia – acid-dependent diseases and hypertension","authors":"G. Calin, V. Istrati, M. Stoica, A. Scurtu, Anatolie Scorpan, Oxana Sirbu","doi":"10.38045/ohrm.2022.3.02","DOIUrl":"https://doi.org/10.38045/ohrm.2022.3.02","url":null,"abstract":"Introduction. With syntropy of CVD and AH, the pathology of the digestive system can exacerbate the course of AH and develop special conditions for increasing the risk of cardiovascular complications. Pharmacotherapy of HD may affect the course and progression of gastroesophageal reflux disease. \u0000Material and methods. The study was conducted using the PubMed, Z-library, NCIB, Medscape, Mendeley databases using the keywords: “syntropy”, “comorbidity”, “arterial hypertension”, “acid-dependent diseases”, “gastric ulcer”, “gastroesophageal reflux disease”. \u0000Results. AH and CVD are quite often observed together, having, moreover, a conditioned commonality of the mechanisms of formation. The proximity of the location with the heart, the commonality of innervation, in the pathology of the esophagus, can create viscero-visceral reflexes and provoke arrhythmias, imitate coronary heart disease. Pathology of the upper gastrointestinal tract can lead to functional disorders of the cardiovascular system, manifested through the autonomic nervous system. The combined course of AH and CVD, observed, according to various sources, from 11.6% to 50%, is not just random, but may have pathogenetic and etiological patterns. Comorbidity of CVD and AH can enhance the development of the main pathological process and lead to disruption of adaptive mechanisms. \u0000Conclusions. The syntropy of AH and CVD requires thorough scientific studies to discover and elucidate the pathogenetic features of the course and methods of better drug therapy.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"29 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124445143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Achievements and topical issues in the field of prevention, diagnosis, and treatment of tuberculosis in children in the Republic of Moldova during the implementation of the “End tb strategy”","authors":"Constantin Iavorschi, S. Alexandru, Stela Kulcitkaia, V. Vilc, E. Tudor, Valentina Bolotnicova, A. Brumaru, Ecaterina Axentii, Vera Oleinic","doi":"10.38045/ohrm.2022.3.04","DOIUrl":"https://doi.org/10.38045/ohrm.2022.3.04","url":null,"abstract":"Introduction. The fight against tuberculosis (TB) as an infectious and socially significant disease and the protection of children's health, representing one of the urgent problems of the 21st century, retain priority positions in national medicine. \u0000Material and methods. Analysis of reporting statistical data on tuberculosis in children for 2016-2021 and the main sections of TB practice. \u0000Results. Epidemiological indicators are presented that characterize the burden of TB incidence cases (new cases and recurrences) in children, its dynamics, as well as the structure of clinical forms, features of modern diagnostics and the evolution of the tuberculosis process in patients of diverse ages. The influence of anti-epidemic measures conditioned by the COVID-19 pandemic was noted. The increasing importance of Mycobacterium tuberculosis drug resistance in the choice of chemotherapy regimen is shown. A quantitative and qualitative assessment of specific prevention, predictors and determinants of TB is given. \u0000Conclusion. The results indicate that the key direction for the prevention and control of TB in the Republic of Moldova should remain the integration and consolidation of efforts in providing anti-TB care to the pediatric population and adolescents.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128991918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"„Phage treatment and wetland technology as intervention strategy to prevent dissemination of antibiotic resistance in surface waters”- a project launch in low-middle in-come countries of Eastern Europe","authors":"E. Ciobanu, C. Croitoru, G. Balan, Vladimir Bernic, O. Burduniuc, Alina Ferdohleb","doi":"10.38045/ohrm.2022.2.05","DOIUrl":"https://doi.org/10.38045/ohrm.2022.2.05","url":null,"abstract":"Introduction. Antimicrobial resistance is a widespread and tough challenge, if not impossible, to limit by biological, physical or geographical barriers. This is the reason behind the \"One Health\" approach, which guides all rules and research plans on antimicrobial resistance worldwide. The abusive and excessive use of antimicrobials in human medicine, veterinary practices, agriculture and aquaculture has traditionally been considered the main reason for the global spread of antimicrobial resistance. The purpose was to assess the epidemiological risk of wastewater as a source of antimicrobial-resistant bacteria concerning public health, focusing on low- and middle-income Eastern European countries. \u0000Material and methods. To achieve this goal, the development of a secure, cost-effective and sustainable technology has been planned, which could easily be introduced in low- and middle-income countries. There have been outlined the following steps: mapping the consumption of antimicrobial emulsions at the national level (primary, cross-sectional study, complete sampling, based on imported data and centralized public acquirement of medicines); research regarding the knowledge, attitudes and practices of the population on antimicrobial resistance (primary, cross-sectional, descriptive study); qualitative and descriptive evaluation of barriers to reduce the phenomenon of antimicrobial resistance by the healthcare services; research regarding the knowledge, attitudes and practices in human and veterinary healthcare on antimicrobial resistance (primary, cross-sectional, descriptive study); screening and investigation of the microbial resistance mechanisms to the strains isolated from patients with infectious pathological processes (preclinical study); analysis of the specific features and sampling of the Constructed Wetlands in Orhei (preclinical study). The Ethics Committee of the Ministry of Health of RM positively approved the Research PhageLand. \u0000Results. The obtained results of this research will contribute to a better understanding of the involved factors that are generating the broadening of antimicrobial resistance and how they influence the transmission among different hosts (bacteria, animals and humans). Moreover, it can also have a major impact to the engineering field and wastewater management companies by expanding the range of tools with sophisticated technologies, designed to reduce the risk of transmitting antimicrobial resistance in wastewater and improve sewerage practices. \u0000Conclusions. The effective use of knowledge and practices in the worldwide fight against antimicrobial resistance, providing useful data, applicable knowledge, efficient, environmentally friendly and cost-effective protocols and technologies, which can be scaled, implemented and used at the European and international levels with no economic or geographical obstacles. \u0000Acknowledgment. The research was conducted in the Republic of Moldova within the JPIAMR projects  (P","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127723541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of the oxidative stress indices in pathogenic bacterial cultures under the action of novel chemical compounds","authors":"C. Lozan-Tirsu, Elena Zariciuc","doi":"10.38045/ohrm.2022.2.04","DOIUrl":"https://doi.org/10.38045/ohrm.2022.2.04","url":null,"abstract":"Introduction. It is known that excessive formation of hydrogen peroxide in the microbial cultures under the action of chemical compounds with antibacterial effects is the first stage in the formation of oxidative stress. Thus, it became appropriate to conduct a study that would make it possible to control the level of oxidative stress induced by chemical compounds in cultures of pathogenic microorganisms. \u0000Material and methods. The objects of the in vitro study were Cu(II) coordination compounds; Co(II), Zn(II) and aromatic propenones synthesized a t the Department of Inorganic Chemistry of the State University of Moldova. Antimicrobial activity was tested on 5 reference strains. The level of oxidative stress was controlled using the hydrogen peroxide test, and the level of lipid peroxidation was determined indirectly by monitoring the product of peroxidation, namely the malondialdehyde. \u0000Results. Under the action of new chemical compounds with antimicrobial properties on reference cultures of Staphylococcus aureus ATCC 25923, Bacillus cereus ГИСК 8035, Escherichia coli ATCC 25922, Shigella sonnei ATCC 25931 and Salmonella enterica (Salmonella abony ГИСК 03/03y) in cultures that create a state of oxidative stress, confirmed by the accumulation of hydrogen peroxide and lipid peroxidation products. \u0000Conclusions. Thus, the process of lipid peroxidation, which follows the pattern of chain reactions, is one of the reactions that lead to the death of cell culture. The level of hydrogen peroxide formed under the action of the tested compounds was also monitored.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127847577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular damage in seronegative spondylarthritis","authors":"M. Stoica, Anatolie Scorpan, O. Sârbu, Alexandru Gorea, V. Istrati","doi":"10.38045/ohrm.2022.2.03","DOIUrl":"https://doi.org/10.38045/ohrm.2022.2.03","url":null,"abstract":"Introduction. Cardiovascular mortality in patients diagnosed with seronegative spondyloarthritis (SSN) is on the rise. Impairment of the cardiovascular system in ankylosing spondylitis (SpA) is 20-40%, in psoriatic arthritis (APs) 18-22% and in reactive arthritis (ARe) 1-3%.Material and methods. The study included 77 patients diagnosed with SSN. Laboratory (erythrocyte sedimentation rate – ESR, C-reactive protein – CRP, fibrinogen) and instrumental (echocardiography – EcoCG, electrocardiogram – ECG) data were analyzed.Results. In 35 patients diagnosed with SpA, the left branch hemiblock of the Hiss bundle was determined – 71% and bradycardia – 57%. Aortic valve (VAo) changes were diagnosed in 54% and left ventricular hypertrophy (LVH) in 57%. Elevated CRP values were found in 34.5% of cases, ESR – 22.8% and fibrinogen – 17.2%. In 24 patients with APs, 33.5% showed VAo induration and fibrosis. Another change diagnosed in these patients was LVH (37.5%). Cardiac conductivity disorders in 25% were due to the left branch hemiblock of the Hiss bundle, and among the increased inflammatory markers were: fibrinogen (16.6%) and CRP (12.5%). In 18 patients with ARe as a rhythm disorder, tachycardia is predominant – 94% and VAo damage in 27.7%. Inflammatory markers with values above the upper limit were fibrinogen (66%) and CRP (33%).Conclusions. Our study showed that SSN is closely related to the inflammatory syn-drome, on which the activity of the disease and the degree of damage to the cardiovascular system depend. Most often the heart is affected with its components.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122857677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of the board of directors in the institutional strategic process within public hospitals","authors":"Ana Niculita","doi":"10.38045/ohrm.2022.2.02","DOIUrl":"https://doi.org/10.38045/ohrm.2022.2.02","url":null,"abstract":"Introduction. According to the normative provisions, the Board of Directors (hereinafter the BD) is an administrative and supervisory body of public hospitals, which, in addition to other exclusive (quite limited) duties, is responsible for the examination and approval of the plans of activity of the hospital. However, just as the expressions \"strategic plan\" or \"strategy\" do not appear in this task, sometimes the involvement of the BD in the examination and approval of institutional strategic documents are omitted. \u0000Material and methods. The purpose of the study is to evaluate the experience of the BD members of the public hospitals in the North region, regarding the involvement in the institutional strategic process. They expressed their opinion on the perceived role in the process of elaboration and implementation of institutional strategies; the vision, mission and set of institutional values, strategic areas, the performance of which they monitor; communication with stakeholders in the strategic context; taking corrective action in a timely manner, etc. The strategies / strategic plans of the medical institutions included in the study were analyzed too. \u0000Results. The results of the study show that the involvement of BD members of the public hospitals in the institutional strategic process is often formal and declarative. \u0000Conclusions. The study emphasizes a superficial attitude of the BD members on the strategic process or the fact that they do not have the necessary competencies to examine the institutional strategies.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126412359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"E-health: Evaluation of the implementation of the Personal Electronic Health Record by family doctors in Greece","authors":"Evangelia Lappa, Aristofanis Paganas, Vasiliki Gkarmiri, O. Giata, Dimitrios Karapoulios","doi":"10.38045/ohrm.2022.2.01","DOIUrl":"https://doi.org/10.38045/ohrm.2022.2.01","url":null,"abstract":"Introduction \u0000Ε-health (eH) is a basic component of current health care provision. The cornerstone of eH is the electronic health record (EHR) system. \u0000Material and methods \u0000The purpose of this survey is to assess the Greek EHR application by Greek family doctors, taking into consideration the brief period of EHR implementation in Greece. We adapted a preexisting questionnaire, with permission, translating and standardizing it in Greek. The questionnaire focused on computer use capability, EHR usage, and efficiency in daily clinical practice, user satisfaction and global user evaluation of the application. 175 family doctors filled out the questionnaire in February 2019. \u0000Results \u0000Low usage rates, minimal facilitation in daily practice, competency issues, and moderate user satisfaction were among our findings. \u0000Conclusions \u0000Greek EHR has several problems and inadequacy areas. Reversing these problems and optimizing the application, then reevaluating the results after a wider period of implementation is important.","PeriodicalId":274368,"journal":{"name":"One Health & Risk Management","volume":"190 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114979771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}