JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH最新文献

{"title":"Structural delving and insilico analysis of proteins of Rhinacanthus Nasutus- an indigenous medicinal plant","authors":"Rubalakshmi G, Nirubama K, Prabhakaran S","doi":"10.46947/joaasr16201633","DOIUrl":"https://doi.org/10.46947/joaasr16201633","url":null,"abstract":"Medicinal plants are staging a comeback and ‘renaissance’ is happening all over the globe. The Medicinal plants products today symbolise safety in contrast to the synthetics that are regarded as unsafe to human and environment. So the medicinal plants have a promising role in to prevent and as well as to cure the diseases. Andrographis is an important genus of the family Acanthacae known for its ethanomedicinal claims and for a variety of medicinal properties. Rhinacanthus nasutus has been used in various folk medicinal preparations and its chemical composition and pharmacological activities have been elaborated recently. Functional characterization of a protein sequence is one of the most frequent problems in biology. This task is usually facilitated by accurate three-dimensional (3-D) structure of the protein. The number of protein sequences that can be modeled, as well as the accuracy of the prediction, is increasing steadily because of the growth and number of known protein sequences and structures as well as improvements in the modeling software. It is currently possible to model, with useful accuracy. Significant parts of approximately one half of all known protein sequences. This research report render a futuristic summary of bioinformatics study of Rhinacanthus nasutus  with emphasis on the current development and future directions, which shall provide tools and resources necessary to understand and uphold advances in this important field. The aim of the present study, 2 proteins of Rhinacanthus nasutus were analysed using bioinformatics tools. Structural prediction and functional characterization of proteins of Rhinacanthus nasutus were done using Expasy Protparm server, 3D structure was done using SWISS MODEL. Plants of different family showing identity 80% and above were selected and its sequences retrieved, aligned using Clustal Omega. phylogenetic tree was constructed for the aligned sequence.  Structure prediction showed that α – helix, random coil, β – turn and extended strand predominates. Phylogenetic analysis of rbcl of Rhinacanthus nasutus reveals that the Plants of Verbenaceae, Bignonaceae, and Fabaceae family are closely related. Hence the present article includes the detailed exploration of Computational tools of protein, and bioinformatic aspects of R.nasutus in an attempt to provide a direction for further research.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128935028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on the Characterization and Utilization of the Banana Peel, Shells of Egg and Prawn for the production of Bioplastics","authors":"Divya S, Rachel Regi Daniel","doi":"10.46947/joaasr352021120","DOIUrl":"https://doi.org/10.46947/joaasr352021120","url":null,"abstract":"Growing level of pollution from the industrial waste or any other form of waste in the environment caused the hazardous effect on the mother planet earth. Plastic pollution played an important role in causing the hazardous effect in both terrestrial and aquatic environment. The entire ecosystem were affected by the pollution. As plastics were non-biodegradable, unsustainable, eco-toxic, increases global warming, leads to biotic and abiotic depletion and reduces the soil fertility. This study were aimed to determine the alternatives for the usage of plastics. As bioplastics were substituted the usage of conventional plastic because they were biodegradable, more sustainable, non-toxic, eco-friendly, no harm to biotic and abiotic factors, increases the soil fertility. These biodegradable plastics were made from the waste materials, such as fruit peels, shells of prawn and egg which acts as a raw material for the production of bioplastic.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125404015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrosynthesis of phenolphthalein using cyclic voltammetry technique","authors":"Reyhaneh zainali, Ali Parsa","doi":"10.46947/joaasr110201782","DOIUrl":"https://doi.org/10.46947/joaasr110201782","url":null,"abstract":"The synthesis of the indicator of phenolphthalein has been investigated in this research by an electrochemical method. In this method, electro-synthesis of phenolphthalein was performed in a 2 M solution of phenol and 1 M solution of phthalic anhydride in sulfuric acid medium, using the cyclic voltammetry technique in a potential range of -0.1 to 1.5 V and scan rate 50 mV/s. Ag/AgCl, platinum and graphite electrodes were respectively used as reference, counter and working electrode. The combination of electro-synthesis in accordance with the detailed steps of the purification and the method of determination of the melting point and FT-IR, HPLC, SEM and UV-Vis devices were used and were confirmed to perform diagnostic tests.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126695726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IR, UV and CV studies of Schiff base metal complexes derived from o-phenylinediamine with chlorobenzaldehyde","authors":"Nazeer M","doi":"10.46947/joaasr19201774","DOIUrl":"https://doi.org/10.46947/joaasr19201774","url":null,"abstract":"A new N2 type Schiff base ligand was prepared by the condensation of o-phenylenediamine with p-chlorobenzaldehyde. The ligand and its mixed-ligand complexes have been characterized by microanalytical data, molar conductance, magnetic susceptibility, IR, UV-Vis., spectra.  The data show that they have composition of the type [ML(ox)]Cl2 where M = Cu(II) and Zn(II). The UV-Vis. and magnetic susceptibility data of all these complexes have adopted square-planar geometry around the central metal ion. Moreover, these complexes have higher electrolytic nature confirmed by the molar conductance data. Furthermore, their magnetic susceptibility values provide evidence for the monomeric nature. From the cyclic voltammetric data, both complexes reveal that these complexes are quasi-reversible.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121685391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium and zinc diffused growth and characterization of strontium L(+) tartrate pentahydrate crystals","authors":"Reema KB, Jagannatha N, Nagaraja KP, Delma D'Souza","doi":"10.46947/joaasr312021113","DOIUrl":"https://doi.org/10.46947/joaasr312021113","url":null,"abstract":"Single crystals of intrinsic strontium L(+) tartrate (IST), Mg2+ doped strontium L(+) tartrate (MDST) and Zn2+ doped strontium L(+) tartrate (ZDST) are grown using gel diffusion reaction method. Optimum condition for crystal growth is established by varying gel density, gel pH, concentration and matrix of supernatant solutions. EDAX analysis is made to measure stoichiometric composition and cationic distribution of the grown crystals. Fourier transform infrared (FTIR) and Laser Raman spectral studies unveil various functional groups in the grown crystals. Thermo gravimetric analysis (TGA) reveal decomposition behavior of the crystals for the temperature range of 30-1000oC. IST, MDST and ZDST crystals inborn with chemical formulae SrC4H4O6.5H2O, Sr0.9987Mg0.0013C4H4O6.5H2O and Sr0.9929Zn0.0071C4H4O6.5H2O respectively.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123026768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Ag doping on structural and optical properties of ZnO nanoparticles","authors":"Mubeenabanu A, Veemaraj T","doi":"10.46947/joaasr19201773","DOIUrl":"https://doi.org/10.46947/joaasr19201773","url":null,"abstract":"Nanocrystals of undoped and silver doped zinc oxide (Zn1-xAgx) were synthesized by co- precipitation method. The samples were calcined at 550°C. The samples were characterized by Ultraviolet Visible Spectroscopy (UV-Vis.) and Particle Size analyzer.Theband gap values of as prepared undoped and doped with silver samples are found to decreasewith increase in temperature on 300 -550°C.The Particle size analyzer studies confirmed that ZnO as a nanoparticles. The ZnO nanoparticle may be used to apply photodegradation of removal of dyes and also make nanorod sensor. ","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131374641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Citrus sinensis peel for eco friendly fragrance on textiles","authors":"Aneetta VJ, Amsamani S","doi":"10.46947/joaasr342021130","DOIUrl":"https://doi.org/10.46947/joaasr342021130","url":null,"abstract":"Food production and processing generates huge amount of waste and by-products, causing irreversible environmental damage. Most of these waste/ by-products are untreated and underutilized, it is either burnt, dumped/ end up in landfills. Safe utilization of these will prevent disease transmission and pollution. So it is important to find ways to treat this waste and give a second life. Food industries waste can be used as raw material in textile industry to produce value added products.   Costumer’s need for special finish on textiles has generated many opportunities for innovative finishes. But these competitions for better sales and profit have led to environmental degradation. Hence finishing using sustainable means is the need of the hour and the investigator selected Citrus sinensis peel an organic waste for the study. Being an unavoidable part in textile treatments, finishes should be highly efficient, durable, and cost effective and manufactured in an environmentally sustainable manner. In this study Nanotechnology, Ultrasonic and Microencapsulation method has been carried out. From subjective evaluation conducted it is clear that nano particle coated fabric have better fragrance than microencapsules padded fabric. The role of Citrus sinensis peel as a natural fragrance finishing agent can be confirmed through this study. Hence this study can be taken as a basis for taking up many more natural materials for fragrance finishing and applied in other textile products.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130192856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Heterogeneity in Colorectal Cancer: Insights from Genetic Profiling","authors":"Mohd Younis, P Sujeetha, T Sangeetha, M Kaviya, K. Bharathi","doi":"10.46947/joaasr352021118","DOIUrl":"https://doi.org/10.46947/joaasr352021118","url":null,"abstract":"The high heterogeneity has become apparent in metastatic colorectal cancer (CRC) and the solitary leading causes of cancer mortality worldwide. Tumor from benign to malignancies derives by gradual and progressive genetic alterations develop into a collection of neoplastic diseases. The parameters are assessed to indicate the extent and prognosis of the disease such as tumor node metastasis stage, tumor grade, microsatellite status, lymphovascular invasion. It is investigated KRAS mutation status in a metastatic to predict the response to anti-epidermal growth factor.  CRC has been described that have prognostic and therapeutic relevance at a distinct molecular level. In the present study, the researcher recruited 65 CRC patients with different stages of the tumor at the right-sided colon, left-sided colon and rectum. We have also recognized left-sided was more complex than right sided CRC patents. In CRC, it has revealed the major differences in the characterization of inflammatory infiltrations and cells location in tumor types. All the patients were stratified into different prognostic and therapeutic groups with the help of these parameters. Though, CRC show intra-tumor heterogeneity due to not clear-cut stratification. However, several CRC patients with single tumor mutations show differences in their mutational status, morphology, inflammatory infiltrate and gene expression. In conclusion, the primary focus on the concept of molecular heterogeneity their metastases and clinical implication in CRC.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"127 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133720390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dissolution studies in few urinary type crystals","authors":"Selvaraju R, Alli J, Sulochana S, Bhuwaneswari M","doi":"10.46947/joaasr17201741","DOIUrl":"https://doi.org/10.46947/joaasr17201741","url":null,"abstract":"Kidney stones are hard, solid particles that form in the urinary tract.  The stones were very small and can pass out of the body without any problems.  Calcium containing stone, especially Calcium Oxalate Monohydrate, Calcium Oxalate Di- hydrate and basic Calcium Phosphate, Calcium Hydrogen Phosphate Di-hydrate, Struvite and are the most commonly occurring stones.  Calcium Oxalate Monohydrate crystals are grown in single diffusion gel growth technique.  The grown crystals are characterized by FTIR, XRD and inhibition studies. A number of medicinal plants were antiurolithiatic activity such as Tribulus terrestriis and Boerhaavia diffusa Linn were carried out. Calcium Oxalate Monohydrate crystals in the presence of the herbal extract of one of the medicinal plants Tribulus terrestris Linn.  The results are discussed.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134157379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vibrational spectra and theoretical calculations of thiocynatobi(pipeidinyl dithiocarbamato)antimony(III)","authors":"Umaralikhan L, Raju S, Liyahathalikhan B, Joseph P.S","doi":"10.46947/joaasr15201632","DOIUrl":"https://doi.org/10.46947/joaasr15201632","url":null,"abstract":"The FTIR and FT-Raman spectra of thiocyanatobi( piperidinyldithiocarbamate) antimony(III) have been recorded in the region4000-400 cm-1. Utilizing the observed FTIR and FT-Raman data, a whole vibrational assignment and analysis of necessary modes of the compounds were carried out. The optimized molecular geometries, vibrational frequencies were calculated by using Hartree-Fock method with HF/3-21G basis set. The calculated HOMO and LUMO energies show that charge transfer occurs within the molecules. Also, several thermodynamic properties, Mullikan’s population analysis, first order hyperpolarizabilitiy, several thermodynamic properties and molecular electrostatic potential were done by the HF method.","PeriodicalId":274343,"journal":{"name":"JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129134246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}