{"title":"Human galectines and their contribution in the chronic colonic inflammation","authors":"Atikah M. Alahmed, Eman Al-Rubaee, Talal H. Noon","doi":"10.47587/sa.2023.4211","DOIUrl":"https://doi.org/10.47587/sa.2023.4211","url":null,"abstract":"Galectins are a group of 16 members that all share an amino acid sequence named carbohydrate recognition domain that binds to a beta-galactoside and produces multiple intra- and extra-cellular functions such as modulating inflammation. Inflammatory bowel disease is a chronic inflammatory disorder of the large and small intestines that comprises two diseases, Crohn disease and Ulcerative Colitis. Ulcerative colitis showed a persistent inflammatory process that affects mainly the colon, this chronic colonic inflammation is affected by several internal and environmental factors. Many galectins are classically expressed in certain gut areas. Organ-specific distribution and abundance of some Galectins make them an important material for many researchers and a useful therapeutic target for different diseases, therefore; their role in colonic inflammation is reviewed to manifest their correlation to chronic diseases such as ulcerative colitis.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129661636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiological review of nosocomial infections caused by Acinetobacter baumanni","authors":"S. Q. Mohammed, A. Noaman, Idriss Saleh Jalil","doi":"10.47587/sa.2022.3110","DOIUrl":"https://doi.org/10.47587/sa.2022.3110","url":null,"abstract":"One of the most important dilemmas that faced patients and medical staff in the past in health institutions is a hospital infection, and it continues at present. Nosocomial infections are caused by almost all organisms but are mostly caused by bacteria, and the species Acinetobacter baumannii is of clinical importance as. It is one of the main causes of nosocomial infections in most regions of the world. These species are characterized by their ability to grow with a wide temperature range between 15- 44 °C, causing common clinical multiples including Hospital-acquired pneumonia, Meningitis. Nosocomial, post-neurosurgical, and bloodstream infections. World Health Organization (WHO) has identified a group of twelve “significant” pathogenic including carbapenem-resistant A. baumannii as the supreme severe pathogens. The universal spread of antimicrobial resistance (AMR) is one of the major universal problems in the twenty-first century. This evaluated that by the year 2050, an infection caused via resistant strains will result in three hundred million diseases. Relevant efforts must be combined to avoid complications caused by the universal spread of antimicrobial-resistant (AMR) strains.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130730592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An optimized assay for early and rapid assessment of behavioral alterations using Caenorhabditis elegans as an alternate animal model","authors":"Sarita Mishra, Rakhi Agarwal","doi":"10.47587/sa.2021.2109","DOIUrl":"https://doi.org/10.47587/sa.2021.2109","url":null,"abstract":"","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131693977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The attitudes of teachers towards scientific research writing in schools of Norbuling CS and Zhemgang CS, Bhutan: A comparative study","authors":"Leki Wangdi","doi":"10.47587/sa.2021.2311","DOIUrl":"https://doi.org/10.47587/sa.2021.2311","url":null,"abstract":"This study resolute the research capabilities and interest among center school teachers of Norbuling and Zhemgang schools of Bhutan. This study employed the descriptive-correlational method. The descriptive method described the characteristics of the respondents, the extent of research capabilities, motivations, and their interest within the field of research. Seventy-seven respondents were drawn from the population. A Stratified sampling method was accustomed to determining samples per stratum. The researchers detected research morals and etiquettes during the collecting process. Descriptive-Inferential statistics were wont to interpret the information. The study revealed that respondents were fascinated by writing research but because of lack of motivation and their capability, they lack within the research process and dissemination. The respondents are abstemiously proficient in their research competencies and research propagation. The number of research capabilities was significantly correlated with motivation and interest. Research support was inadequate; a positive research environment must be provided to encourage them in research writing. The findings of the study provide data of two different schools to grasp the factors affecting the research capabilities of public-school teachers. The college heads can come up with a workable decision to enhance research capabilities and manage their resources, policies, time, space, and personnel for optimum effect. The fast trend in instructional technology and innovative approaches and teaching pedagogies, knowledge, and skills within the research of all academic professionals is important. Conducting research becomes now mandatory within the educational institutions within Bhutan; thus, needs continuous assessment to supply a community of teacher-researchers.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125416291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phytochemical screening and proximate composition of bitter kola (Garcinia kola) and oil palm (Elaeis guinensis) syrup","authors":"Osagiede L.A, Odita N.G, Akawo N.O","doi":"10.47587/sa.2023.4301","DOIUrl":"https://doi.org/10.47587/sa.2023.4301","url":null,"abstract":"The rising cases of diet-related diseases such as obesity, atherosclerotic cardiovascular disease, inflammatory diseases, diabetes mellitus and cancer have stimulated interest in the use of plant-based food as an alternative to synthetic food. G. kola and palm syrup are plant-based food with proven nutritional and health benefits. In the present study, phytochemical and proximate analysis of (Elaies guineensis) syrup, bitter kola Garcinia kola). Preliminary phytochemical screening, proximate analysis and mineral analysis were conducted. The aqueous extracts of palm syrup, cola seeds and their infusion were further subjected to highperformance liquid chromatography analysis to determine the phenolic compounds, organic acids and sugar composition of the extracts. Result of preliminary phytochemical screening, mineral composition, as well as phenolic compound and organic acid indicate that Garcinia kola, and palm syrup are nutritionally suitable. Results show that the proximate analysis of oil palm syrup and bitter kola shows high concentrations of crude protein (9.52), ash (4.02), crude fibre (12.23), and fat (15.01) compare to palm syrup (P< 0.05). While palm syrup showed high concentrations of Moisture content (34.50) and Carbohydrates (61.67). while The Oil palm syrup contained saponins, glycoside and flavonoids. While Bitter kola had a wider range of phytochemicals including the above-mentioned alkaloids, tannins and terpenoids.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125502108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of potassium and boron on growth and chemical composition of Cucumber (Armenia sp.) irrigated by saline water","authors":"S. E. Sayed, F. Hellal, H. Abdel-Kader","doi":"10.47587/sa.2021.2306","DOIUrl":"https://doi.org/10.47587/sa.2021.2306","url":null,"abstract":"Field experiments were conducted at farmer's field, Kerdasa, El–Giza governorate, Egypt during two winter seasons of (2019/2020) to study the effects of soil-applied potassium fertilization (0, 50, 75, 100 kg K2O fed) and boron foliar spray (0, 50, 100 and 150 ppm) and their interaction on growth and chemical composition of cucumber plant irrigated by saline water. The results indicated that soil application of potassium and boron foliar spray successfully mitigated the deleterious effects of salt stress and influenced the growth and nutrient content of the cucumber plant. Soil application of 100 kg K2O fed combined with 150 ppm boron foliar spray improved the growth and chemical constituents of cucumber, in terms of chlorophyll (SPAD), the tissue water content of leaves and fruit, fresh and dry weight, fruit length and diameter, and nutrient content (N, P, and K) of fruits in both the first and second cut, while reduced the sodium content. The combined treatment of potassium at 100 kg K2O fedand boron spraying at 150 ppm was found to be more effective for the cucumber plant to enhance the growth performance and the nutrient content as compared with the control under saline water irrigation conditions.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126836405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of metallic nanoparticles on microorganism: A review","authors":"Hawraa F. Wali, H. M. Nahab","doi":"10.47587/sa.2021.2213","DOIUrl":"https://doi.org/10.47587/sa.2021.2213","url":null,"abstract":"","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121289299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular docking and dynamic study with polyphenolic constituents as inhibitors of human tyrosinase enzyme for hyperpigmentation therapy and skin complexion management","authors":"Diptendu Sarkar, G. D. Mandal","doi":"10.47587/sa.2023.4209","DOIUrl":"https://doi.org/10.47587/sa.2023.4209","url":null,"abstract":"This research has revealed the molecular docking and dynamics study with few phytomolecules against the human tyrosinase enzyme protein in order to control hyperpigmentation and skin tone in the future. This study set out to find certain phytomolecules that have the capacity to attach to the protein model for the tyrosinase enzyme and block the enzyme's ability to function. We took into account all nine molecules in total, coupled with a protein model of the tyrosinase enzyme, for docking, with energy ranges between -5.3 and -7.4 Kcal/mol. The greatest lowest binding energy for quercetin was -7.4 Kcal/mol. With a model protein, this molecule displayed a variety of interactions, including Van der Waals, conventional hydrogen bonds, covalent bonds, and carbon hydrogen bonds. In this interaction, 3 hydrogen bonds were discovered. The other compounds, such as kaempferol and chlorogenic acid, also demonstrated correct binding with the model tyrosinase and had -7.2 Kcal/mol energy with 3 and 5 hydrogen bonds, respectively. Quercetin, Kaempferol, and Chlorogenic acid are therefore thought to be far more potent than Benztropine and may be used in further clinical research.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121811918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Innovative framework design of an intelligent detection and monitoring system (IDMS) to leverage National Security","authors":"Okonta O. Emmanuel, Ajani Dele, Okonta I. Love","doi":"10.47587/sa.2023.4302","DOIUrl":"https://doi.org/10.47587/sa.2023.4302","url":null,"abstract":"Intrusion monitoring is the act of monitoring unwanted traffic on a network or a device, analysing them for signs of possible incidents, which are violations or imminent threats of violation of computer security policies, acceptable use policies, or standard security practices. Intrusion detection is the process of detecting a possible compromise or events occurring in a computer system or network. An IDMS can be a piece of installed software or a physical intelligent appliance that monitors network traffic in order to detect and prevent unwanted activity and events such as illegal and malicious traffic, traffic that violates security policy, and traffic that violates acceptable use policies. This innovative design primarily focused on identifying possible incidents, logging information about them, attempting to stop them, and reporting them to security administrators. In addition, try to inoculate the system to prevent similar attacks using recognisable signature patterns and this will enhance National Security and prevent unwarranted cyber-attacks on organizations and important National resources","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122604396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sonophotocatalytic treatment of thiazine (azure a) dye from wastewater using TiO2 film","authors":"Alaa T. Hamzah","doi":"10.47587/sa.2022.3203","DOIUrl":"https://doi.org/10.47587/sa.2022.3203","url":null,"abstract":"This research is including the efficiency of four methods of advanced oxidation processes and compares them for decolonizing the textile dye Azure A in an aqueous solution. These methods are TiO2 only, ultrasound with titanium dioxide (TiO2 +US) and titanium dioxide ultraviolet (TiO2 + UV), and titanium dioxide with ultraviolet with ultrasound (TiO2 +UV +US). The aim is to determine the best method of treatment for the mineralization of color. All the experiments have been done by using sonophotocatalytic experimental setup. The study includes the investigating effects of dye concentration, temperature, and pH. Complete degradation has been achieved in a somewhat short time of 60 min. The maximum removal of color was found in higher pH and temperature where at T=308K the removal percentage is 40%, 55%, 60%, and 99% and at pH=8 are 30%, 55.5%, 66%, and 98.5% by four methods consecution shown the removal rate that increases with decreases initial dye concentration, and also that the ratio of removal increases with the rise of temperature, which decreases activated energy of the reaction. As far as pH is concerned it appears that the ratio of removal decreased in an acidic medium. The decolonization reaction was found to follow first-order kinetics concerning the dye concentration.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122906588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}