Chemical Engineering Journal最新文献

{"title":"Coanda-effect-inspired curved polyacrylonitrile/sodium lignosulfonate nanofiber interphase with a negatively charged surface for durable zinc anodes","authors":"Tianyu Zhang, Haolan Tao, Feng Yang, Le Zhou, Wenzhuo Gao, Bin-Bin Xie, Hongfei Wang, Yong Hu","doi":"10.1016/j.cej.2026.182687","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182687","url":null,"abstract":"The interfacial instability of the Zn anode hinders practical aqueous Zn-ion batteries (ZIBs). Existing artificial layers focus on static field distribution and zincophilic sites but overlook dynamic ion transport near the electrode. Inspired by the Coanda effect, we construct a composite interfacial layer comprising polyacrylonitrile (PAN) and sodium lignosulfonate (LS) on Zn foil (PAN-LS@Zn) via in-situ electrospinning. The curved fibrous topologies of PAN, coupled with the negatively charged surface of LS, homogenize the Zn<ce:sup loc=\"post\">2+</ce:sup> flux and establish a local ion reservoir that substantially elevates the Sand's time, thereby mitigating concentration polarization. Concurrently, the preferential interaction between the functional groups and the (101)/(100) planes steers Zn nucleation along (002). Consequently, the PAN-LS@Zn anode enables a Zn//Zn symmetric cell to achieve a cycling life of 4345 h at 1 mA cm<ce:sup loc=\"post\">−2</ce:sup>/1 mAh cm<ce:sup loc=\"post\">−2</ce:sup>, and sustains over 210 h even at a stringent depth of discharge of 68.5%. Paired with a Zn<ce:inf loc=\"post\">2</ce:inf>V<ce:inf loc=\"post\">2</ce:inf>O<ce:inf loc=\"post\">7</ce:inf> cathode, the full battery retains 93.7% of its initial capacity after 1100 cycles at 10 A g<ce:sup loc=\"post\">−1</ce:sup>. Moreover, the practical viability is substantiated under low N/P ratios and in pouch cell configurations. This work opens a new avenue for durable ZIBs via Coanda-effect-inspired interface design.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"25 1","pages":"182687"},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MnS@nZVI-polymeric resin for sustainable selenium oxyanions removal from water: Bridging experimental evidence, mechanistic insights, density functional theory, and life cycle assessment","authors":"Mahvish Abbasi, Osama Shaheen Rizvi, Ahsan Javed, Hajra Javed, Asfra Rizwan Toor, Syed Zajif Hussain, Asim Jilani, Zubair Khalid, Eakalak Khan, Tauqeer Abbas","doi":"10.1016/j.cej.2026.182752","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182752","url":null,"abstract":"Manganese sulfide encapsulated nano zero-valent iron-immobilized anionic resin (MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR) was synthesized for treating selenium oxyanions [Se(IV) and Se(VI)] in water. Batch experimental results showed that the removal kinetics of Se(IV) and Se(VI) were fast; 2 g/L of MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR was able to remove &gt;99% of both Se oxyanions from water containing 10 mg/L of each Se oxyanion. The performance of MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR in removing Se oxyanions was pH-independent and highly effective in the presence of competing ions and other heavy metals, with removal efficiencies of &gt;99%. Comprehensive XPS analyses were conducted on fresh, aged, exhausted, and regenerated MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR to determine the roles of two reactive layers (MnS and nZVI) present on the polymeric resin in Se removal and to elucidate the removal mechanism. The MnS outer layer limits the rapid oxidation of Fe(0) to Fe(III) in aging experiments. The removal of both Se oxyanions by aged MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR was comparable to that of fresh MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR (&gt;99%). Regeneration experiments demonstrated the exceptional reusability of MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR after five consecutive cycles, making it suitable for practical application in treating Se-contaminated water. Both adsorption and reduction were involved in the removal of Se oxyanions. The density functional theory indicated that the adsorption of both Se(IV)/Se(VI) was spontaneous and favorable. In column experiments, MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR treated 14,688 bed volumes (filtration time = 102 days) of water containing Se(VI) (C<ce:inf loc=\"post\">0</ce:inf> = 1000 μg/L) with removal &gt;99%. Life cycle impact assessment demonstrated that MnS-nFe<ce:sup loc=\"post\">0</ce:sup>AR reduces environmental impacts by ~38% compared to unmodified AR, highlighting its potential as green adsorbent for Se-contaminated water treatment.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"180 1","pages":"182752"},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-uniformly decorated CdS-Bi2S3 quantum dot aerogels for efficient S-scheme photocatalytic CO2 reduction","authors":"Guangtao Zhang, Jiahang Ni, Guocan Jiang, Ping Lu, Mingchen Li, Junlong Zou, Jing Zhou, Jin Wang, Sheng Li, Guangbo Chen, Zhengquan Li","doi":"10.1016/j.cej.2026.182714","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182714","url":null,"abstract":"S–scheme heterojunction photocatalysts based on three-dimensional (3D) quantum dot (QD) gel networks have emerged as promising platforms for CO<ce:inf loc=\"post\">2</ce:inf> photoreduction. However, constructing efficient S–scheme heterointerfaces within 3D QD gel architectures remains challenging due to the inherent trade–off between maximizing interfacial charge separation and preserving accessible catalytic sites. Conventional uniform coating strategies often fail to achieve this balance, either blocking active sites with thick layers or providing insufficient interfacial contact. Herein, we report a facile single–cycle successive ionic layer adsorption and reaction (SILAR) strategy to achieve non–uniform Bi<ce:inf loc=\"post\">2</ce:inf>S<ce:inf loc=\"post\">3</ce:inf> nanocluster deposition on a continuous CdS QD gel skeleton, enabling the construction of a high–performance S–scheme heterojunction. This island–like architecture generates abundant intimate heterointerfaces for efficient charge migration while maintaining exposed CdS surface sites for CO<ce:inf loc=\"post\">2</ce:inf> adsorption and reduction. Comprehensive investigations including <ce:italic>in-situ</ce:italic> X–ray photoelectron spectroscopy (XPS), time–resolved photoluminescence (TRPL), and density functional theory (DFT) calculations support the proposed S–scheme charge–transfer pathway, in which selective interfacial recombination preserves the highly reducing electrons on CdS for CO<ce:inf loc=\"post\">2</ce:inf>–to–CH<ce:inf loc=\"post\">4</ce:inf> conversion. The optimized CdS–Bi<ce:inf loc=\"post\">2</ce:inf>S<ce:inf loc=\"post\">3</ce:inf>–5.5% (molar ratio of Bi to Cd) catalyst achieves a CH<ce:inf loc=\"post\">4</ce:inf> evolution rate of 142.2 μmol g<ce:sup loc=\"post\">−1</ce:sup> h<ce:sup loc=\"post\">−1</ce:sup>, representing an approximately 9.0–fold enhancement over pristine CdS gel, with a CH<ce:inf loc=\"post\">4</ce:inf> selectivity of 94.3%. Moreover, localized Bi<ce:inf loc=\"post\">2</ce:inf>S<ce:inf loc=\"post\">3</ce:inf> domains provide an additional photothermal contribution that facilitates CO<ce:inf loc=\"post\">2</ce:inf> reduction kinetics. This work demonstrates that single–cycle SILAR–enabled non–uniform deposition offers an effective strategy for balancing interfacial charge dynamics and surface reactivity in QD gel photocatalysts.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"244 1","pages":"182714"},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron salt assisted engineering of activated carbons for high performance aqueous zinc ion capacitors and supercapacitors","authors":"Recep Yuksel, Naile Karakehya","doi":"10.1016/j.cej.2026.182767","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182767","url":null,"abstract":"The rational regulation of carbon microstructure through iron salt-assisted carbonization provides an effective strategy for developing high-performance biomass-derived carbon electrodes. Herein, microcrystalline cellulose (MCC) was impregnated with FeCl<ce:inf loc=\"post\">3</ce:inf> or FeSO<ce:inf loc=\"post\">4</ce:inf> and pre‑carbonized at 400 or 800 °C, followed by KOH activation to investigate the influence of iron precursor chemistry on structural evolution and electrochemical performance. The results reveal two distinct carbonization pathways. FeCl<ce:inf loc=\"post\">3</ce:inf> promotes catalytic graphitization through iron-mediated carbon reconstruction, producing highly graphitized carbon with an interlayer spacing of 0.3362 nm and a graphitization degree of 90.7%. In contrast, FeSO<ce:inf loc=\"post\">4</ce:inf> suppresses graphitic ordering while facilitating the formation of a hierarchically porous architecture with an ultrahigh specific surface area of 2615 m<ce:sup loc=\"post\">2</ce:sup> g<ce:sup loc=\"post\">−1</ce:sup>. Owing to the synergistic combination of abundant accessible pores and favorable surface chemistry, the S-MCC-800-AC electrode delivered superior electrochemical performance, achieving specific capacitances of 240.4 F g<ce:sup loc=\"post\">−1</ce:sup> in a symmetric supercapacitor and 622.6 F g<ce:sup loc=\"post\">−1</ce:sup> in an aqueous Zn-ion hybrid capacitor at 0.1 A g<ce:sup loc=\"post\">−1</ce:sup>. Conversely, although FeCl<ce:inf loc=\"post\">3</ce:inf>-derived carbon exhibited rapid charge-transfer kinetics due to its highly graphitized framework, excessive graphitization significantly reduced the accessible surface area and consequently limited charge-storage capability.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"244 1","pages":"182767"},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Techno-economic and environmental assessment of biomass-to-sustainable aviation fuel production via gasification coupled with a Fischer-Tropsch process","authors":"Chunyu Liu, Yuwen Shao, Hongbin Wan, Jiaqi Jiao, Guanyi Chen, Beibei Yan, Zhanjun Cheng, Weiming Yi, Sunu Herwi Pranolo, Obie Farobie, Jingang Yao","doi":"10.1016/j.cej.2026.182699","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182699","url":null,"abstract":"Sustainable aviation fuel (SAF) is widely recognized as one of the most promising pathways for reducing greenhouse gas emissions from the aviation sector. This work presents an integrated modeling framework for SAF production from dual fluidized bed (DFB) biomass gasification and Fischer-Tropsch (FT) synthesis. By combining process simulation, energy analysis and techno-economic evaluation within a unified platform, the proposed framework enables a comprehensive assessment of technical, environmental and economic performance. At 100.0 kg/h biomass, 800 °C and S/B = 0.8, the process produces 15.0 kg/h SAF. The exported liquid-product energy ratio is 35.1%, while useful-energy utilization reaches 41.8% when internal gas recycling and DFB heat transfer are included. Within the defined foreground gate-to-gate boundary, the SAF-specific global warming potential (GWP) and acidification potential (AP) were 31.06 g CO<ce:inf loc=\"post\">2</ce:inf>-eq/kg SAF and 2.64 × 10<ce:sup loc=\"post\">−3</ce:sup> g SO<ce:inf loc=\"post\">2</ce:inf>-eq/kg SAF, respectively, after LHV-based energy allocation. The screening-level techno-economic assessment gives a total capital investment of approximately 4.8 × 10<ce:sup loc=\"post\">6</ce:sup> USD and an SAF production cost of 6.7 USD/kg, indicating limited economic competitiveness under the present conceptual small-scale design basis. Overall, the work develops an integrated framework for biomass-to-SAF assessment, enabling systematic identification of thermodynamic, environmental and economic bottlenecks to support process optimization.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"78 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The preparation of dual carbon dioxide-responsive gel and its application in the rapid self-healing of cement sheath","authors":"Yujie Ying, Yuetong Wu, Jintang Guo, Miaomiao Hu","doi":"10.1016/j.cej.2026.182753","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182753","url":null,"abstract":"The cement sheaths in CCUS cementing are prone to crack when subjected to coupled loads, threatening to the safety of oil and gas development. Compared with traditional repair methods, self-healing technology can achieve active repair of micro-cracks without human intervention. Among various self-healing technologies, polymer self-healing materials stand out due to diverse properties and structures. However, the repair speed of polymer self-healing materials is slow and the addition amount is high, thus increasing the cost. To achieve the unified optimization of self-healing efficiency, dosage and cost, the dual carbon dioxide-responsive gel NP-Ca were prepared by introducing tertiary amine groups and phosphate groups. The NP-Ca owns good thermal stability and water absorption properties, showing excellent application properties in well cementing. In the self-healing test, the cementitious composites containing 0.25%, 0.5% and 1% NP-Ca respectively attain 95.76%, 99.67% and 95.23% crack volume self-healing rate after 7d healing. The self-healing mechanism is confirmed by reactive force field molecular dynamics simulation and experiments. When contacting with carbon dioxide, NP-Ca can expand to seal micro-cracks. The tertiary amine groups can capture carbon dioxide to form carbonates and the phosphate groups loses the cross-linking effect with calcium ions to release additional calcium ions. The carbonates and calcium ions can react to form calcium carbonate, thus repair the micro-cracks of cement matrix. Compared with the existing work, NP-Ca can demonstrate a higher self-healing efficiency at a lower addition amount, which exhibits a new path for cement sheath self-healing.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"78 1","pages":"182753"},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carrier confinement in type-I 2D van der Waals heterostructures: Band-alignment engineering and emerging photodetection applications","authors":"Waqas Ahmad, Akbar Bashir, Muhammad Ahsan Saeed, Wen Lei, Hammad Ghazanfar, Zhiming Wang, Hocine Bahlouli","doi":"10.1016/j.cej.2026.182648","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182648","url":null,"abstract":"Type-I band alignment in two-dimensional (2D) van der Waals (vdW) heterostructures offers a compelling platform for carrier confinement, enabling optoelectronic functionalities distinct from widely studied type-II systems. Unlike charge-separating architectures, type-I configurations localize both electrons and holes within the same material. This carrier confinement promotes enhanced radiative recombination and can suppress dark current, which is advantageous for photodetection. In this focused review, we examine the fundamental mechanisms governing carrier confinement in type-I 2D vdW heterostructures, including band-offset engineering, interfacial coupling, and quantum confinement effects. Theoretical frameworks, such as Anderson's rule and density functional theory, are discussed to clarify band alignment formation and tunability. We further summarize recent advances in the design of lateral and vertical vdW heterostructures, emphasizing interface engineering strategies for precise control of electronic properties. Key experimental and computational techniques, including Kelvin probe force microscopy and first-principles simulations, are highlighted for probing interfacial energetics and validating band alignment. Finally, we critically evaluate recent progress in photodetectors based on type-I vdW heterostructures, demonstrating their potential for broadband operation, high responsivity, and fast response. Emerging opportunities and remaining challenges are outlined to guide future development of confined-carrier optoelectronic systems.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"11 1","pages":"182648"},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Realization of high-capacity Lithium metal batteries across carbonate- and ether-based electrolytes via adoption of organic–inorganic hybrid surface protection material","authors":"Jinhyeon Jo, Changhyeon Lee, Kiyeon Sim, KwangSup Eom","doi":"10.1016/j.cej.2026.182804","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182804","url":null,"abstract":"In lithium metal batteries, modifying lithium metal with a stable solid electrolyte interphase (SEI) is of tremendous interest for the development of safe and cost-effective energy storage systems. Herein, we propose an organic-inorganic hybrid material as a protective SEI layer composed of Mg(NO<ce:inf loc=\"post\">3</ce:inf>)<ce:inf loc=\"post\">2</ce:inf> and poly(vinylidene fluoride-<ce:italic>co</ce:italic>-hexafluoropropylene) (PVDF-HFP) to stabilize the Li metal interface by facile drop-casting onto the electrodes. The sustained release of Mg<ce:sup loc=\"post\">2+</ce:sup> cations may contribute to interfacial anion decomposition and the formation of the inorganic-rich SEI components. The inorganic-rich SEI provides high ionic conductivity and mechanical strength, effectively suppressing Li dendrite formation during Li plating/stripping. Furthermore, the phase-separated PVDF-HFP generates a grain-boundary-rich organic layer that may facilitate Li-ion diffusion, while its inherent flexibility accommodates large volume changes during cycling, ensuring interfacial stability under high-energy conditions. As a result, the MN-HFP@Li electrode achieves a high Coulombic efficiency of 94% over 250 cycles in Li||Cu half cells and exhibits stable cycling performance in full cells with a high-loading NCM cathode (≈ 4.4 mAh cm<ce:sup loc=\"post\">−2</ce:sup>). Furthermore, the MN-HFP@Li configuration delivers outstanding long-term cycling stability exceeding 500 cycles when paired with an LFP cathode. This strategy offers a simple and scalable route toward practical realization of high-energy lithium metal batteries (LMBs).","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"9 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesostructure engineering decouples the lifetime-selectivity trade-off in methanol-to-aromatics reaction over ZSM-5 catalysts","authors":"Zhaoqi Ye, Zhizheng Sheng, Kexin Yan, Yifan Zhang, Yaxuan Xu, Yahong Zhang, Hongbin Zhang, Yi Tang","doi":"10.1016/j.cej.2026.182445","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182445","url":null,"abstract":"Balancing molecular diffusion and spatial confinement is central to designing ZSM-5 catalysts for methanol-to-aromatics (MTA), yet their individual roles are difficult to disentangle because mesostructural changes often couple with variations in composition or acidity. Herein, we construct a mesostructure-regulated ZSM-5 platform with comparable framework composition, acid properties, and Al siting <ce:italic>via</ce:italic> a low-water, seed-induced synthesis. By simply switching alkali metal ions (Na<ce:sup loc=\"post\">+</ce:sup><ce:italic>vs.</ce:italic> K<ce:sup loc=\"post\">+</ce:sup>) and introducing trace amounts of TPABr, two continuously adjustable mesostructural regimes are obtained: open mesoporous nanocrystal assemblies (Na<ce:sup loc=\"post\">+</ce:sup> system) and confined intracrystalline mesoporous single crystals (K<ce:sup loc=\"post\">+</ce:sup> system). MTA catalysis reveals that these two mesostructural regimes impose intrinsically competing demands. Open mesopores enhance molecular transport and coke accommodation, extending catalyst lifetime, but promote premature olefin desorption and weaken BTX shape selectivity. Confined intracrystalline mesopores act as reaction reservoirs that retain intermediates, boosting aromatization and BTX selectivity, yet they are more prone to internal coke accumulation. This establishes a diffusion-confinement competition that governs the lifetime-selectivity trade-off. Guided by this mechanistic distinction, we further construct Z5-Na8@K0, an intraparticle integration of a diffusion-favorable nanocrystal-assembly core and a confinement-providing shell. This architecture moves the lifetime-selectivity frontier forward, achieving a more favorable balance of stability, aromatics selectivity, and cumulative target-product productivity. This work provides a decoupled platform for elucidating structure-performance relationships in zeolites and sheds new light on the rational catalyst design for complex reactions governed by coupled transport and confinement.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"31 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"All-in-one SERS biochip for high-efficiency isolation and multiplexed profiling of exosomes for osteosarcoma diagnosis","authors":"Junjie Zhang, Xinyi Wu, Ying Jin, Tingting Liu, Na Xue, Cheng Wang, Yi Yang, Qi Liu, Yu-Chen Wang, Yue Yuan, Honglin Liu, Zhenzhen Han","doi":"10.1016/j.cej.2026.182676","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182676","url":null,"abstract":"Early diagnosis of osteosarcoma (OS) is critical for improving patient survival. Although exosomes have emerged as promising noninvasive biomarkers for early cancer detection, their clinical translation remains hindered by technical limitations in high-efficiency isolation and multiplex molecular profiling. To address these challenges, we develop a novel all-in-one surface-enhanced Raman spectroscopy (SERS) biochip that integrates herringbone-embedded microfluidics, tangential flow filtration (TFF), and SERS detection, enabling simultaneous Ca<ce:sup loc=\"post\">2+</ce:sup>-dependent TIM4 affinity capture, EDTA-mediated release, and multiplexed on-device detection of exosomes. Leveraging TIM4-based affinity SERS substrates in conjunction with TFF, the platform achieves a high exosome recovery efficiency of 87.8%, outperforming the gold-standard ultracentrifugation method and avoiding SERS substrate aggregation and microchannel clogging. Multiplex quantitative analysis of three exosomal protein biomarkers using antibody-conjugated SERS probes further enables precise discrimination among different OS cell lines. Using plasma-derived exosomes from OS patients (<ce:italic>n</ce:italic> = 15) and healthy controls (<ce:italic>n</ce:italic> = 15), we construct a logistic regression diagnostic model. On an independent test set (40% of samples), the model achieves a diagnostic accuracy of 93.33%, with a sensitivity of 90%, a specificity of 96.67%, and an area under the curve of 0.93. To our knowledge, this is the first study to integrate TIM4-based affinity capture, TFF purification, and SERS-based multiplex profiling with machine learning for noninvasive OS diagnosis. This strategy not only overcomes key technical barriers in exosome-based cancer diagnostics, such as low isolation efficiency and limited multiplexing capability, but also presents significant clinical value for noninvasive OS detection.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"464 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}