Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)最新文献

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Preliminary experiment results of a 1.75D ultrasound array 1.75D超声阵列的初步实验结果
Minming Huang, P. Guo, N. Chen, Quing Zhu
{"title":"Preliminary experiment results of a 1.75D ultrasound array","authors":"Minming Huang, P. Guo, N. Chen, Quing Zhu","doi":"10.1109/NEBC.2001.924715","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924715","url":null,"abstract":"The authors have designed a prototype two-dimensional ultrasound and near infrared (NIR) diffusive light imager for simultaneous imaging. Here, they show preliminary results obtained from an improved imager which replaces the lower resolution ultrasound system in the combined imager with a high resolution 1.75 D ultrasound array.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126911645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces 原子力显微镜作为细胞剥离技术量化成骨细胞与种植体表面粘附的可行性
D. Gianoli, S. Kohles, N. Burnham, M. B. Clark, C. Brown, J. Kenealy
{"title":"The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces","authors":"D. Gianoli, S. Kohles, N. Burnham, M. B. Clark, C. Brown, J. Kenealy","doi":"10.1109/NEBC.2001.924692","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924692","url":null,"abstract":"The preliminary data acquired for the roughness parameter (Ra) demonstrate that there is a clear difference between the 4 different surface preparations studied. Based on previous work it can be expected that once each sample has been seeded with cells, there will exist strong variations among the cellular activity on each disk surface. While it is not the goal of this project to quantify differences among the levels of cellular activity, it is believed that they can be inferred from differences in adhesive strength as well as visual differences among the images produced by the AFM. It is expected that differences in extracellular matrix production will be chiefly responsible for not only differences in cellular phenotypes among samples but also differences in adhesive strengths.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126160265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The Mahalanobis distance as a metric in dynamic light scattering particle size analysis: model studies 马氏距离在动态光散射粒度分析中的度量:模型研究
S. Dubin, S. Zietz, K. L. Gabriel, D. Gabriel
{"title":"The Mahalanobis distance as a metric in dynamic light scattering particle size analysis: model studies","authors":"S. Dubin, S. Zietz, K. L. Gabriel, D. Gabriel","doi":"10.1109/NEBC.2001.924723","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924723","url":null,"abstract":"Dynamic Light Scattering (DLS) has been applied to examination of several clinically and biologically important materials including the lens of the eye. The clinical potential of DLS has been demonstrated empirically both in vivo and in vitro. The data supplied by DLS investigation is inherently multivariate and its most efficient interpretation requires a multivariate approach which includes the variability among specimens as well as any correlation among the variables (e.g., across the particle size distribution). The authors discuss the Mahalanobis distance as a metric for statistical analysis of DLS data using model-generated data.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122670297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bump Around automated bumper car 自动碰碰车
D. Martins, M. DaSilva, W. Pruehsner, J. Enderle
{"title":"Bump Around automated bumper car","authors":"D. Martins, M. DaSilva, W. Pruehsner, J. Enderle","doi":"10.1109/NEBC.2001.924735","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924735","url":null,"abstract":"\"Bump Around\" is a project intended to stimulate and entertain children with disabilities by putting them into motion. The bumper car is designed to meet the needs of one individual, but is intended to be versatile enough to accommodate a broad range of children. The bumper car makes life more enjoyable for the underprivileged children that use them. Safety features provided include a system for avoiding collisions with other objects, other students, and walls utilizing ultrasonic proximity sensors. In addition, the car has a Remote Off switch, which is given to the instructor, who has the ability to shut down the car. The vehicle is activated using a toggle switch and is driven by pressing a push-button switch that can be mounted in varying locations to meet the particular needs of the children using the device. An H-Bridge motor control circuit is also presented that has the capability of handling the high currents required for controlling the device.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134534115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental characterization of bone anisotropic poroelasticity parameters 骨各向异性孔隙弹性参数的实验表征
D. W. Young, S. Kohles
{"title":"Experimental characterization of bone anisotropic poroelasticity parameters","authors":"D. W. Young, S. Kohles","doi":"10.1109/NEBC.2001.924710","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924710","url":null,"abstract":"Outlines anisotropic poroelasticity and develops a method for establishing the level of anisotropy in bone, and for determining anisotropic poroelastic parameters mechanically. This work is part of an ongoing effort in the authors' laboratory. It incorporates tests that have been previously developed and employed to study anisotropic solid and fluid properties in bone. This work incorporates a means for validating the results of both drained and undrained parameters through multiple mechanical tests and the use of ultrasound. The culmination of this work will result in the description of bone anisotropic solid and transport properties as well as tissue density. The authors' work attempts to fill the gap in knowledge of the bone anisotropic material parameters. The data will be useful in the developed of complex FEA models which can describe bone response to mechanical stimuli. Furthermore, the test methods developed can be used to study differences in healthy and diseased bone, the effects of aging and disuse, as well as in the mechanical assessment of engineered bone.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126518120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An in vitro model for vascular smooth muscle trauma due to angioplasty 血管成形术致血管平滑肌损伤的体外模型
A.B. Bhavnani, K. Barbee
{"title":"An in vitro model for vascular smooth muscle trauma due to angioplasty","authors":"A.B. Bhavnani, K. Barbee","doi":"10.1109/NEBC.2001.924721","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924721","url":null,"abstract":"Percutaneous Transluminal Coronary Angioplasty (PTCA) has proven to be beneficial to patients in danger of death from myocardial infarction. The major limitation with this modern success in conquering coronary (or any other vessel) obstruction is the phenomenon of restenosis. The pathology underlying restenosis differs substantially from the pathology of the disease leading to the obstruction of the blood vessel, namely, atherosclerosis. PTCA mitigates the consequences of an old disease, atherosclerosis, while at the same time elicits a new pathology, restenosis. The purpose of this study was to determine the mechanical loading conditions that VSM cells can withstand without leading to restenosis. We have designed a device for applying a uniform and isotropic 2-D strain to a flexible cell culture membrane. This device allows precise control of the applied strain and strain rate and quantification of cell responses in terms of cell membrane damage. The determination of the threshold criteria for VSM cell injury has important implications for the possible modification and/or automation of the PTCA technique in order to minimize VSM injury and avoid restenosis.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133012691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A graphical user interface and system to measure foot pressures in diabetic patients 一个测量糖尿病患者足压的图形用户界面和系统
Jennifer N. Novak, E. Bauer, P. Blume, James, Beaty, John, Enderle
{"title":"A graphical user interface and system to measure foot pressures in diabetic patients","authors":"Jennifer N. Novak, E. Bauer, P. Blume, James, Beaty, John, Enderle","doi":"10.1109/NEBC.2001.924702","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924702","url":null,"abstract":"Many techniques are available to analyze the plantar pressure of the foot both quantitatively and qualitatively. In this paper, the two techniques that will be used to analyze the planter pressures are the Harris Mat and Tekscan. The purpose of this project is to optimize the system of measuring the plantar pressures of the feet of a diabetic patient. A correlation between the two techniques will be determined in order to save time for the physician and patient, while allowing for the prevention of ulceration in the diabetic patient. This correlation will lead to the development of a program that can process the scanned Harris Mat image and yield quantitative results. Once the image has been processed, it will be imported into a Matlab graphical user interface (GUI), where the physician can analyze pressure distributions and areas of increased pressure.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"125 30","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120929339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A new model of passive limb motion 一种新的被动肢体运动模型
J. Fee
{"title":"A new model of passive limb motion","authors":"J. Fee","doi":"10.1109/NEBC.2001.924724","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924724","url":null,"abstract":"Reports on ongoing work in the modeling of the leg drop pendulum test as a means of assessment in spastic cerebral palsy. In previous papers it was demonstrated that a passive model might fit data taken from the passive motion of limbs with and without spastic cerebral palsy outside of the influence of the monosynaptic reflex loop. This paper tests that model further by performing leg drop pendulum tests under anesthesia and muscle paralysis on 11 subjects. The model which best fits the data is different from others reported in the literature. The model consists of 2 nonlinear springs and 2 nonlinear dampers, one for each direction of motion. The nonlinearities consist of simple power functions of position for the springs and velocity for the dampers. Two additional damping elements are added based on the inverse of velocity as the motion comes to rest. The paper demonstrates the accuracy of this model.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122736201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Preliminary mechanical characterization of a tissue scaffold for coronary artery replacement 冠状动脉置换术组织支架的初步力学特性研究
K. Young, E. Prechtel, R. Kronengold, M. Marcolongo
{"title":"Preliminary mechanical characterization of a tissue scaffold for coronary artery replacement","authors":"K. Young, E. Prechtel, R. Kronengold, M. Marcolongo","doi":"10.1109/NEBC.2001.924703","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924703","url":null,"abstract":"A first step has been established toward design and processing parameters for a tissue engineered vascular graft. Compliance curves mimic the shape of those of the native coronary artery. Refinements in processing may lead to a mechanically suitable construct for tissue engineering a small diameter vascular graft.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124868247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimization of drive screw pitch in a pulsatile ventricle assist device 脉动心室辅助装置驱动螺杆螺距的优化
N. Vitale, G. Hirschman, W. A. Smith
{"title":"Optimization of drive screw pitch in a pulsatile ventricle assist device","authors":"N. Vitale, G. Hirschman, W. A. Smith","doi":"10.1109/NEBC.2001.924708","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924708","url":null,"abstract":"A dynamic simulation model of an electric-motor-driven pulsatile ventricle assist device has been developed and used to optimize key design parameters, including the pitch of the magnetic screw that translates motor rotary motion into linear pulsatile motion.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132233639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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