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2013 International Workshop on Magnetic Particle Imaging (IWMPI)最新文献

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Experimental setup of receive coils with transaxial sensitivity profiles 具有跨轴灵敏度曲线的接收线圈实验装置
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528355
T. Sattel, S. Heinitz, M. Erbe, T. Buzug
{"title":"Experimental setup of receive coils with transaxial sensitivity profiles","authors":"T. Sattel, S. Heinitz, M. Erbe, T. Buzug","doi":"10.1109/IWMPI.2013.6528355","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528355","url":null,"abstract":"The present work describes the realization of a tube-shaped receive coil set for 2D imaging, which provides sensitivity profiles with high homogeneity. The idea is to resemble a sinusoidal current distribution, which is known to generate an ideal field distribution. To conclude from a magnetic field generated by an electromagnetic coil to it's receive properties, the law of reciprocity is applied. Good agreement with the simulation is obtained by first magnetic field measurements.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123924771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Finding the Sentinel Lymph Node with a handheld differential magnetometer 用手持式差分磁强计寻找前哨淋巴结
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528347
S. Waanders, M. Visscher, T. Oderkerk, B. Ten Haken
{"title":"Finding the Sentinel Lymph Node with a handheld differential magnetometer","authors":"S. Waanders, M. Visscher, T. Oderkerk, B. Ten Haken","doi":"10.1109/IWMPI.2013.6528347","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528347","url":null,"abstract":"In cancer staging, the Sentinel Lymph Node (SLN) procedure is a common method to assess the stage to which a cancer has progressed[1]. Currently, the SLN procedure is performed by injecting both a blue dye and a radionuclide tracer near or into the tumor area, and the first lymph node(s) draining the tumor area are located by means of visual inspection and a gamma probe which detects the radiation emitted by the radionuclide tracer. This combined procedure has proven to be very reliable and is used frequently, but suffers from some serious drawbacks that limit its applicability in general practice. These problems are mostly caused by the usage of ionizing radiation, which poses occupational hazards to medical staff and requires extensive logistics, which not all hospitals can offer.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121278716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
First hybrid MPI-MRI imaging system as integrated design for mice and rats: Description of the instrumentation setup 首个用于小鼠和大鼠的MPI-MRI混合成像系统集成设计:仪器设置描述
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528363
J. Franke, U. Heinen, L. Matthies, V. Niemann, F. Jaspard, M. Heidenreich, T. Buzug
{"title":"First hybrid MPI-MRI imaging system as integrated design for mice and rats: Description of the instrumentation setup","authors":"J. Franke, U. Heinen, L. Matthies, V. Niemann, F. Jaspard, M. Heidenreich, T. Buzug","doi":"10.1109/IWMPI.2013.6528363","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528363","url":null,"abstract":"This hybrid MPI-MRI imaging system (see Fig. 1 RIGHT) is currently under assembly at the research labs of Bruker BioSpin MRI GmbH, whereas single components were already tested. The magnetic field strength and the magnetic field gradient were measured to be up to <sub>Bz</sub>=0.495 T and up to G<sub>z</sub>=2.2 T/m for the PF and the SF, respectively (see Fig. 1 LEFT). The MRI gradient strengths were determined to be G<sub>x</sub>=0.84 mT/A/m, G<sub>y</sub>=0.9 mT/A/m, G<sub>z</sub>=0.87 mT/A/m (I<sub>max</sub>=300 A) and the MRI RF coil was tuned to the Larmor frequency of protons at 0.495 T. The DF resonant circuits were tuned to excitation frequencies of around 25 kHz. With expected maximal DF amplitude of 20 mT and the strongest SF gradient strength a field of view of 18×36×36 mm<sup>3</sup> could be reached.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128694769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Magnetic contaminant imaging using High-TC SQUID ultra-low field MRI technologies 利用高tc SQUID超低场MRI技术进行磁性污染物成像
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528386
S. Tanaka, S. Tsunaki, M. Yamamoto, Y. Hatsukade, J. Hatta
{"title":"Magnetic contaminant imaging using High-TC SQUID ultra-low field MRI technologies","authors":"S. Tanaka, S. Tsunaki, M. Yamamoto, Y. Hatsukade, J. Hatta","doi":"10.1109/IWMPI.2013.6528386","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528386","url":null,"abstract":"We applied back projection method and got a 2D image of the bottle as shown in Fig.1. Two separated bright area can be seen. Each spot is corresponding to the 1H of water. Then we applied this technology to the contaminant detection in food. Two water bottles, one with a small aluminum ball of φ1.5 mm, the other without, were prepared. Figure 2 shows the comparison of the 1H signal intensity between with an aluminum small ball and without. In case of the existing of the aluminum ball, one dip can be observed in the spectrum. At present we don't use MPI technology, but MPI will be applied to the system to enhance the signal in the near future.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124182656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interacting magnetic nanoparticle clusters for enhancing magnetic particle imaging performance 相互作用的磁性纳米颗粒团簇增强磁颗粒成像性能
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528380
S. Sarangi, A. Brazdeikis
{"title":"Interacting magnetic nanoparticle clusters for enhancing magnetic particle imaging performance","authors":"S. Sarangi, A. Brazdeikis","doi":"10.1109/IWMPI.2013.6528380","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528380","url":null,"abstract":"In this paper, improved magnetic properties of interacting MNPs may be very useful not only for MPI but also for magnetic particle hyperthermia, magnetic relaxation imaging, and contrast enhanced magnetic resonance imaging.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126809041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recovery of the magnetic particle imaging system matrix using compressed sensing reconstruction 利用压缩感知重构恢复磁粉成像系统矩阵
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528330
T. Knopp, A. Weber
{"title":"Recovery of the magnetic particle imaging system matrix using compressed sensing reconstruction","authors":"T. Knopp, A. Weber","doi":"10.1109/IWMPI.2013.6528330","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528330","url":null,"abstract":"In magnetic particle imaging the system matrix is commonly obtained by performing a tedious calibration scan, which requires measuring the system response at various positions in the field-of-view. In this work, a method for significantly reducing the number of required calibration scans is proposed. It exploits the fact that the MPI system matrix can be sparsified using certain basis transformations such as the discrete Fourier transformation and applies compressed sensing reconstruction techniques. Experiments show that the calibration scan can be accelerated by a factor of ten with only marginal loss of image quality.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122122981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Improving conspicuity in MPI by equalization of the “broad tails” of the MPI point spread function 通过均衡MPI点扩散函数的“宽尾”来提高MPI的显著性
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528384
D. A. Price, G. Sun, P. Goodwill, E. Saritas, S. Conolly
{"title":"Improving conspicuity in MPI by equalization of the “broad tails” of the MPI point spread function","authors":"D. A. Price, G. Sun, P. Goodwill, E. Saritas, S. Conolly","doi":"10.1109/IWMPI.2013.6528384","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528384","url":null,"abstract":"The point spread function (PSF) in MPI has been found to be the derivative of the Langevin function. This PSF has noticeably longer “tails” than a single Gaussian. These tails of the PSF manifest as baseline blurring, which significantly decreases contrast and “glare” in MPI. Here, we develop a robust post-processing method to equalize (similar to deconvolution) the PSF, to essentially remove these tails. Fortunately we find this equalization method does not incur the enormous loss of SNR observed in conventional deconvolution.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131323860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Imaging atherosclerotic plaques in vivo using peptide-functionalized iron oxide nanoparticles 利用肽功能化氧化铁纳米颗粒在体内成像动脉粥样硬化斑块
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528388
L. B. Drews, L. Croft, H. Kosuge, E. Saritas, P. Goodwill, M. McConnell, S. Conolly, M. Tirrell
{"title":"Imaging atherosclerotic plaques in vivo using peptide-functionalized iron oxide nanoparticles","authors":"L. B. Drews, L. Croft, H. Kosuge, E. Saritas, P. Goodwill, M. McConnell, S. Conolly, M. Tirrell","doi":"10.1109/IWMPI.2013.6528388","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528388","url":null,"abstract":"Atherosclerosis, or the formation of plaques in the arterial wall, leads to cardiovascular disease, the number one cause of death in the United States. Atherosclerosis develops through multiple stages, which makes it a particularly difficult disease to detect. Markers of these different stages of plaque development have been discovered, however. Our work aims to selectively target and deliver a contrast agent to atherosclerotic plaques through the use of peptides that bind to unique markers of plaque development. Our goal is to use Magnetic Particle Imaging (MPI) to diagnose atherosclerotic plaques.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134274601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Mri of spio-labeled mesenchymal stem cells in an animal model of acute renal failure at a clinical 3T system 临床3T系统急性肾衰竭动物模型中脊髓标记间充质干细胞的Mri
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528362
H. Ittrich, C. Lange, F. Toegel, A. Zander, C. Westenfelder, G. Adam, C. Nolte-Ernsting
{"title":"Mri of spio-labeled mesenchymal stem cells in an animal model of acute renal failure at a clinical 3T system","authors":"H. Ittrich, C. Lange, F. Toegel, A. Zander, C. Westenfelder, G. Adam, C. Nolte-Ernsting","doi":"10.1109/IWMPI.2013.6528362","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528362","url":null,"abstract":"Optimized methods in MRI allow for qualitative and quantitative in-vivo cell-tracking and monitoring of organ distribution of SPIO-labeled MSC in clinical acute renal failure (ARF) in rate at a clinical 3T MR system. The study demonstrates the potential of in-vivo MRI for qualitative tracking and quantification of SPIO-labeled stem cells in future therapeutic treatment protocols.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115861160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo magnetic nanoparticle cytometer for stem cells in small animals 小动物干细胞体内磁性纳米颗粒细胞仪
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528383
W. Yang, B. Zheng, T. Vazin, P. Goodwill, E. Saritas, D. Schaffer, S. Conolly
{"title":"In vivo magnetic nanoparticle cytometer for stem cells in small animals","authors":"W. Yang, B. Zheng, T. Vazin, P. Goodwill, E. Saritas, D. Schaffer, S. Conolly","doi":"10.1109/IWMPI.2013.6528383","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528383","url":null,"abstract":"Parkinson's Disease (PD) is a degenerative disorder that causes the malfunction and death of neurons in the substantia nigra and afflicts hundreds of thousands of Americans. There is no known cure for PD. However, stem cell transplant therapy holds promise for reversing the effects of PD. Preclinically, the mouse model of stem cell therapy for PD is used to assess stem cell viability and analyze neuron regeneration in the substantia nigra. However, tracking stem cell viability in these experiments remains difficult at best because conventional imaging methods may inaccurately quantify stem cell number in vivo due to penetration depth or other effects. Here, we propose a new magnetic nanoparticle cytometer for small animals to quantify cells implanted in vivo labeled with superparamagnetic iron oxide (SPIO) nanoparticles. This cytometer, which uses MPI principles, is well-suited for determining stem cell viability as it provides linear signals for accurate quantification of cell number in vivo without suffering from depth or tissue attenuation or relying on ionizing radiation or radioactive materials with short half-lives.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115739029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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