New Nigerian Journal of Clinical Research最新文献_第3页

A histopathological study of 752 female lesions of the breast with benign biological behavior 752例女性乳腺良性病变的组织病理学研究

New Nigerian Journal of Clinical Research Pub Date : 2020-02-01 DOI: 10.4103/nnjcr.nnjcr_3_20

I. Emmanuel, Olufunmilayo Abobarin, Samuel Abaniwo, Patrick Nzekwe, Samuel Richard, B. Mandong

{"title":"A histopathological study of 752 female lesions of the breast with benign biological behavior","authors":"I. Emmanuel, Olufunmilayo Abobarin, Samuel Abaniwo, Patrick Nzekwe, Samuel Richard, B. Mandong","doi":"10.4103/nnjcr.nnjcr_3_20","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_3_20","url":null,"abstract":"Introduction: Lesions of the breast with benign biological behavior (LBBBB) are nonmalignant pathologies. They underlie the most common cause of symptomatic breast problems. It is estimated that 30% of women at sometimes in their lifetime are afflicted with LBBBB that requires treatment. The objective of this work is to study the histological pattern of LBBBB in females at the Jos University Teaching Hospital, Nigeria, between January 2010 and December 2020, relating this finding to age and site, and comparing this with reports in published literature. Methodology: This is a descriptive retrospective research of consecutive cases of LBBBBs diagnosed at the Jos University Teaching Hospital, Nigeria, between January 2010 and December 2020. The records at the department were used to obtain the lesions so diagnosed. Results: A total of 1122 female cases of breast lesions were diagnosed during the period of the study: 370 (32.98%) malignancies and 752 (67.02%) benign (malignancy-to-benignity ratio, 1:2.03). Of the 752 cases of female LBBBB, 382 (50.80%) were on the right, whereas 370 (49.20%) were on the left. The five most common LBBBB were fibroadenoma, 382 (50.79%); fibrocystic change, 126 (16.76%); acute mastitis/abscess, 38 (5.05%); intraductal papilloma, 29 (3.86%); and fat necrosis, 21 (2.79%). The age range was 4–85 years, with mean, median, and mode of 30.60 ± 12.0 years, 28 years, and 23 years, respectively. Conclusion: Two-third of breast lesions in the female breast in our environment are benign and slightly more common on the right. Fibroadenoma is the most common histological type constituting more than half of cases and together with fibrocystic change (the second most common lesion) makes up two-third of all cases. The reproductive age is overwhelmingly the commonly affected group. We recommend increasing research in this field to help predict the risk of subsequent malignancy in affected women with LBBB in our environment.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132712433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of endometriosis among women undergoing diagnostic laparoscopy at a tertiary hospital in North-Western Nigeria 在尼日利亚西北部的一家三级医院接受诊断性腹腔镜检查的妇女中子宫内膜异位症的患病率

New Nigerian Journal of Clinical Research Pub Date : 2020-02-01 DOI: 10.4103/nnjcr.nnjcr_43_19

N. Adamou, U. Umar, Faiza Mohammed

{"title":"Prevalence of endometriosis among women undergoing diagnostic laparoscopy at a tertiary hospital in North-Western Nigeria","authors":"N. Adamou, U. Umar, Faiza Mohammed","doi":"10.4103/nnjcr.nnjcr_43_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_43_19","url":null,"abstract":"Background: Endometriosis is a complex gynecological disease in its physiopathological aspects and clinical implications. Signs and symptoms include pain and subfertility. The most common sites are pelvic organs and peritoneum. This study evaluated the prevalence of endometriosis among women undergoing diagnostic laparoscopy for chronic pelvic pain and infertility at a tertiary hospital in North-Western Nigeria over a 3-year period (from January 1, 2015, to December 31, 2017). Materials and Methods: A retrospective study of women who had diagnostic laparoscopy for chronic pelvic pain and infertility in our hospital was conducted. Theater operation register records and files of women who had laparoscopy for the same indications were retrieved and reviewed. Information on sociodemographic and reproductive characteristics as well as laparoscopic findings were extracted and reviewed. Results: The total number of women who had laparoscopy for the above indications over the study period was 92, of which 74 files were retrieved and analyzed. The prevalence of endometriosis was found to be 8.1%. Endometriosis was found to be more common in women whose complaint was chronic pelvic pain and/or dysmenorrhea. Conclusion: Endometriosis is a common, underreported gynecologic condition among women of reproductive age group presenting with infertility and chronic pelvic pain.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121036394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histological pattern of breast diseases in children and adolescents in North Central Nigeria 尼日利亚中北部儿童和青少年乳腺疾病的组织学模式

New Nigerian Journal of Clinical Research Pub Date : 2020-02-01 DOI: 10.4103/nnjcr.nnjcr_10_20

S. Raphael, K. Ezike

{"title":"Histological pattern of breast diseases in children and adolescents in North Central Nigeria","authors":"S. Raphael, K. Ezike","doi":"10.4103/nnjcr.nnjcr_10_20","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_10_20","url":null,"abstract":"Background: Breast lesions are said to be rare and predominantly benign in the pediatric population. However, several case reports of malignant breast lesions in this demography exist, hence, the need to carefully examine breast masses when seen in children and adolescents to ascertain their nature. Aim: The aim of this study is to document the frequency, sex, and age distribution of the histologic subtypes of breast diseases seen in children and adolescents in a district hospital. Patients and Methods: Data were collated retrospectively from patients' request forms and duplicate copies of histology reports of all cases of breast lesions seen over a 5-year period at the pathology unit of Asokoro District hospital, Abuja, North Central Nigeria. Data were analyzed using Microsoft Excel, expressed using measures of central tendencies and percentages, and displayed using simple tables. Results: One-hundred and thirty-six cases of breast lesions were seen in the children and adolescent population (≤19 years), representing 16% of all the breast specimens during the study period. Females accounted for 97% with female-to-male ratio of 33:1. Their ages ranged from 10 to 19 years with modal age at presentation of 16 years. One (0.74%) case of invasive cribriform carcinoma was seen in a 17-year old boy. They presented as unilateral breast lesions in 88.6%, bilateral lesions in 9.6%, and unstated in 5.8% of patients, respectively. The most common lesion was fibroadenoma (74.3%), followed by fibrocystic change (10.3%). Conclusion: Breast lesions are common among older children and adolescents in our environment, mostly benign in nature and strikingly affect females. Fibroadenoma was the most common histologic lesion seen.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129447450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Premalignant and malignant lesions of the esophagus: A single-institutional experience 食管的癌前病变和恶性病变:单一机构的经验

New Nigerian Journal of Clinical Research Pub Date : 2020-02-01 DOI: 10.4103/nnjcr.nnjcr_22_20

M. Ajani, O. Adegoke, I. Nwanji, S. Omenai, K. Akande

{"title":"Premalignant and malignant lesions of the esophagus: A single-institutional experience","authors":"M. Ajani, O. Adegoke, I. Nwanji, S. Omenai, K. Akande","doi":"10.4103/nnjcr.nnjcr_22_20","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_22_20","url":null,"abstract":"Background: Esophageal malignancy is a highly aggressive tumor with a poor prognosis. A number of lesions occurring in the esophagus are associated with a high risk of malignant transformation. While the patterns of esophageal cancers have been documented in a number of African countries, there is a limited data on the Nigerian situation. This study was aimed at reviewing the histological patterns of premalignant and malignant lesions of the esophagus. Methods: This was a 10-year retrospective study of histologically confirmed premalignant and malignant lesions of the esophagus seen at the University College Hospital, Ibadan, between January 2009 and December 2018. Data retrieved from the departmental records were analyzed using the SPSS computer software version 20.0. Results: There were 45 cases diagnosed with premalignant lesions and 32 cases diagnosed with malignant lesions out of the 363 biopsies during the study period. The most common premalignant lesion was Barret's esophagus (68.9%). Premalignant lesions were more common in males (64.4%). The mean age for patients with a diagnosis of premalignant lesions was 55 years. The mean age at the diagnosis for esophageal cancer was 61.5 years. Squamous cell carcinoma was the predominant histological subtype seen (65.6%) with adenocarcinomas accounting for the remainder of cases (35.4%). Conclusion: Squamous cell carcinoma is the most common malignancy of the esophagus in our study. Adenocarcinomas of the esophagus were not as rare as documented in previous African studies. This finding may imply a changing pattern in esophageal malignancies in tandem with the pattern in Western countries.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125897416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical success of fixed space maintainers: Conventional band and loop versus fiber-reinforced composite loop space maintainer 固定空间维持器的临床成功:传统的带子和环与纤维增强复合环空间维持器

New Nigerian Journal of Clinical Research Pub Date : 2020-01-01 DOI: 10.4103/nnjcr.nnjcr_32_19

R. Rani, S. Chachra, A. Dhindsa, Manu Sharma

引用次数: 2

Prevalence of urinary tract infections and risk factors among pregnant women attending antenatal clinics in government primary health-care centers in Akure, Nigeria 在尼日利亚阿库雷政府初级保健中心产前诊所就诊的孕妇中尿路感染的流行率和危险因素

New Nigerian Journal of Clinical Research Pub Date : 2020-01-01 DOI: 10.4103/nnjcr.nnjcr_18_19

I. Simon-Oke, O. Odeyemi, M. Oniya

{"title":"Prevalence of urinary tract infections and risk factors among pregnant women attending antenatal clinics in government primary health-care centers in Akure, Nigeria","authors":"I. Simon-Oke, O. Odeyemi, M. Oniya","doi":"10.4103/nnjcr.nnjcr_18_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_18_19","url":null,"abstract":"Background: Urinary tract infection (UTI) has become the most common bacterial infection in humans, both at the community and hospital settings. It has been reported in all age groups and in both sexes. This is also a leading cause of Gram-negative sepsis in hospitalized patients. This study was carried out to identify and evaluate the associated risk factors of UTIs in relation to the sociodemographic characteristics among pregnant women in the study area. Materials and Methods: A cross-sectional study was conducted from February to June, 2018, on the urine of pregnant women, and the sociodemographic information of the women was collected. A total of 300 clean midstream urine samples were collected, and a general urine microscopic examination and culture were carried out. Results: Out of the 300 urine samples cultured, 183 (61.0%) yielded significant growth of urinary pathogens, whereas 117 (39.0%) yielded either insignificant growth or no growth of any urinary pathogen. Prevalence of UTI was statistically significantly associated with the type of toilet used, symptoms of UTI, and previous history of UTI (P < 0.05). Conclusion: This study justifies that pregnant women are at high risk of UTI; therefore, screening of pregnant women during antenatal clinics should be considered very important to avoid complications. Health education with regular antenatal and personal hygiene is recommended as a precautionary measure to UTI.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129380796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peripheral arterial disease and its predictors in type 2 diabetic patients in Nnewi, South-Eastern Nigeria 尼日利亚东南部Nnewi地区2型糖尿病患者外周动脉疾病及其预测因素

New Nigerian Journal of Clinical Research Pub Date : 2020-01-01 DOI: 10.4103/nnjcr.nnjcr_34_19

O. Oguejiofor, C. Onwukwe, C. Ezeude, E. Okonkwo, J. Nwalozie, Charles Odenigbo, C. Oguejiofor

{"title":"Peripheral arterial disease and its predictors in type 2 diabetic patients in Nnewi, South-Eastern Nigeria","authors":"O. Oguejiofor, C. Onwukwe, C. Ezeude, E. Okonkwo, J. Nwalozie, Charles Odenigbo, C. Oguejiofor","doi":"10.4103/nnjcr.nnjcr_34_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_34_19","url":null,"abstract":"Background: Peripheral arterial disease (PAD) is a cause of foot disease in type 2 diabetes mellitus (T2DM) patients. Data on associated predictors of PAD in Nigerian T2DM patients are scanty, especially from Southeastern Nigeria. Objectives: The objective was to evaluate the prevalence and predictors of PAD in T2DM patients in Southeastern Nigeria. Materials and Methods: This is a cross-sectional study involving consenting T2DM patients at the Diabetes Clinic of the Nnamdi Azikiwe University Teaching Hospital, Nnewi, Southeastern Nigeria. History was obtained and physical examination was done on the study participants. Doppler ultrasound of the peripheral vessels was done using the Imex PD II Doppler device. Records of fasting plasma glucose on the day of Doppler assessment, glycated hemoglobin, fasting lipid profile, and electrocardiogram, done within the preceding 3 months, were obtained from the patients' clinic folders. PAD was defined as ankle–brachial pressure index <0.9 or >1.3. Data collection was done using researcher-administered study pro forma and analyzed using the Statistical Package for the Social Sciences version 20.P < 0.05 was considered statistically significant. Results: Of 100 T2DM patients (45 males and 55 females) recruited for the study, 74 (30 [40.5%] males and 44 [59.5%] females) had a complete data for analysis. The prevalence of PAD among the study participants was 59.5%. Significant predictors of PAD include the duration of DM, abdominal obesity, hypertension, triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C) levels. Conclusion: PAD is prevalent in T2DM patients in Southeastern Nigeria, with duration of DM, abdominal obesity, hypertension, TG, and HDL-C levels being significant predictors of PAD.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117056040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myasthenia gravis-like symptoms in an adolescent with amyotrophic lateral sclerosis 青少年肌萎缩侧索硬化症的重症肌无力样症状

New Nigerian Journal of Clinical Research Pub Date : 2020-01-01 DOI: 10.4103/nnjcr.nnjcr_14_17

Uduak Offiong, P. Alabi

引用次数: 0

Self-reported ear symptoms among mobile phone users at a tertiary institution 大专院校手机使用者自我报告的耳部症状

New Nigerian Journal of Clinical Research Pub Date : 2020-01-01 DOI: 10.4103/nnjcr.nnjcr_2_19

Auwal Adamu, Abdulazeez Ahmed, A. Aluko, Yasir J. Nuhu, E. Kolo

{"title":"Self-reported ear symptoms among mobile phone users at a tertiary institution","authors":"Auwal Adamu, Abdulazeez Ahmed, A. Aluko, Yasir J. Nuhu, E. Kolo","doi":"10.4103/nnjcr.nnjcr_2_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_2_19","url":null,"abstract":"Background: Globally, the use of mobile phones has increased considerably and as such there have been increasing concern about its effects on the ear. It was observed that university students used mobile phones excessively not only for communication purpose but also for leisure (such as listening to music/radio), thus possibly predisposing their ears to untoward effects. Aims: The aim was to determine the prevalence of self-reported ear symptoms among mobile phone users. Materials and Methods: It was a cross-sectional descriptive study, conducted among university students aged 16–40 years. Participants were recruited using multistage random sampling technique. A self-administered, pretested, and validated questionnaire was used to collect the data, which were analyzed using Statistical Product and Service Solution version 20.0. Results: A total of 388 participants were recruited into the study. The duration of usage of mobile phone ranged between 1 and 17 years with a mean of 7 ± 3.5 years. The time spent on phone use per day ranged between 1 and 16 h with a mean of 2.6 ± 2.3 h. The overall prevalence of self-reported ear symptoms was 29.1%. Eighty-four (21.6%) of the respondents had ear pain, 68 (17.5%) had tinnitus, 44 (11.3%) had hearing impairment, 20 (5.2%) had vertigo, and 38 (9.8%) had other symptoms. The self-reported ear symptoms were found to have a statistically significant association with the time spent on the phone per day (P = 0.001) and the duration of use of the phone in years (P = 0.001). Conclusions: The prevalence of self-reported ear symptoms among mobile phone users was low. More detailed studies on the association between mobile phone use and ear symptoms, particularly tinnitus and hearing impairment would be worthwhile.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134087787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Dental caries, missing teeth, and oral health behavior among smokers 吸烟者的龋齿、缺牙和口腔健康行为

New Nigerian Journal of Clinical Research Pub Date : 2020-01-01 DOI: 10.4103/nnjcr.nnjcr_22_19

C. Azodo, A. Umoh

{"title":"Dental caries, missing teeth, and oral health behavior among smokers","authors":"C. Azodo, A. Umoh","doi":"10.4103/nnjcr.nnjcr_22_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_22_19","url":null,"abstract":"Objective: To determine dental caries, missing teeth, and oral health behavior among smokers and to correlate same with nicotine dependence. Materials and Methods: The study was carried out among smokers and age-matched nonsmokers in Benin-City, Edo State Nigeria. Nicotine dependence, periodontal knowledge, subjectively rated periodontal status, and oral self-care were assessed with questionnaire while carious, missing, and filled teeth were recorded during oral examination. Results: The mean periodontal health knowledge was 1.65 for smokers and 2.75 for nonsmokers. The mean subjectively rated periodontal status was 4.25 for smokers and 3.40 for nonsmokers. The mean oral health behavior was 9.05 for smokers and 10.50 for nonsmokers. The mean carious teeth was 2.10 for smokers and was 1.00 for nonsmokers. Nicotine addiction was negative correlated with periodontal knowledge, oral behavior, carious teeth, filled teeth, and abrasion teeth but positively correlated with subjectively rated periodontal status and missing teeth. Conclusion: Smokers had lower periodontal knowledge, poorer subjectively rated periodontal health, poorer oral self-care behavior and more carious teeth than nonsmokers. Further studies to include smokers with high nicotine dependence are recommended.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130787275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1