Myasthenia gravis-like symptoms in an adolescent with amyotrophic lateral sclerosis

Abstract

Juvenile onset amyotrophic lateral sclerosis (JALS) is a rare form of motor neuron disease. The symptoms of upper and lower motor neuron degeneration manifest before 25 years of age. Juvenile ALS is more frequently familial in nature though sporadic forms have been found to occur. Myasthenia gravis (MG) also a neuromuscular disorder shares some common features with ALS. There have been reports of atypical forms of juvenile ALS; however, the occurrence with MG in the same patient is a rare. Here is presented a 13-year-old male child with a history and clinical feature of JALS coexisting with MG symptomatology.