New Nigerian Journal of Clinical Research最新文献

{"title":"Young people's willingness to go for HIV/acquired immunodeficiency syndrome counseling and testing in oluku community in South Nigeria","authors":"K. Okafor, Vincent Yakubu Adam, E. Azuike, Greg Abiaziem","doi":"10.4103/nnjcr.nnjcr_33_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_33_19","url":null,"abstract":"Background: Young people are vulnerable to HIV/acquired immunodeficiency syndrome (AIDS) as they significantly contribute to new HIV infections in Nigeria and sub-Saharan Africa. HIV counseling and testing (HCT) provides an opportunity for increased awareness, prevention, treatment, care, and support for HIV/AIDS and contributes to the prevention and control of HIV/AIDS. Objective: This study aims to determine the HIV/AIDS awareness, knowledge of methods of prevention and transmission of HIV/AIDS, HIV status of sexual partner, and willingness to go for HIV/AIDS counseling and testing (HCT) among young people in Oluku Community, Ovia North East, local government, Edo State, South South, Nigeria. Materials and Methods: This was a descriptive cross-sectional study conducted between January and June, 2013, using multistage sampling method. Data were collected using interviewer-administered questionnaire adapted from the 2007 National HIV/AIDS and Reproductive Health Survey (NARHS) plus. Results: A total of 400 young people participated in this study; their mean age was 17.8 years (3.9 years). There were more females (211 [52.8%]) than males (189 [47.3%]). Majority (92.3%) of the young people were aware of HIV/AIDS; most heard of it via electronic media (81%), peers (63.5%), and parents (55.5%). Majority knew the methods of transmission of HIV/AIDS as having multiple sexual partners (80.0%), sharing sharps (78.3%), blood transmission (71.5%), and having unprotected sex (69.8%). Abstinence (50.1%) and condom use (37.8%) and faithfulness to partner (5.3%) were the methods practiced by most young people to prevent disease transmission and pregnancy. Most (61.9%) of the young people did not know the HIV/AIDS status of their partners before sexual intercourse. More than two-thirds (68.0%) had never gone for HCT, however majority (73.0%) of them were willing to go for HCT. Conclusion and Recommendations: Most young people were aware of HIV/AIDS and the methods of transmission, whereas more than two-thirds had never gone for HCT. However, majority of them were willing to go for HCT. Efforts should be geared toward improving access to HCT services by using stand-alone, mobile/outreach, and health facility-based HCT centers and community enlightenment on the importance of avoiding premarital sex and their roles in reducing HIV/AIDS and other sexually transmitted infection transmission.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131239567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurological manifestation of human immunodeficiency virus/Aids","authors":"G. Onwuegbuzie, R. Reng","doi":"10.4103/nnjcr.nnjcr_20_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_20_19","url":null,"abstract":"Neurologic complications occur in human immunodeficiency virus (HIV)-infected patients, but only a few of these complications are directly related to HIV infection of the central nervous system (CNS). The virus can affect virtually every aspect of the central and peripheral nervous system, directly or indirectly with the major target being the immune system, including lymphocytes, microglia, and macrophages. Common neurologic manifestations include meningitis, minor and major cognitive impairment, stroke, seizure, immune-mediated effects and opportunistic infection. Diagnosis usually involves a detailed clinical evaluation, including mini-mental scale, as well as lumbar puncture for serology and culture, nerve conduction studies, electromyogram, and neuroimaging. Treatment is usually targeted at the HIV using highly active antiretroviral therapy (HAART) and specific disease entities. CNS side effects of HAART may be transient, while others may require withdrawal of the antiretroviral drug.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125612636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biting preferences of blackfly in two endemic communities of ose local government area, Ondo state, Nigeria","authors":"O. Afolabi","doi":"10.4103/nnjcr.nnjcr_38_18","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_38_18","url":null,"abstract":"Context: Blackflies are hematophagous dipterans who transmit Onchocerca volvulus; the pathogen of onchocerciasis. Aims: The study was undertaken in Imeri and Idogun to evaluate the knowledge of respondents on the biting preferences of blackflies. Settings and Design: The design is an observational study in epidemiology which involves the use of structured questionnaire to obtain useful epidemiological information from the respondents. Materials and Methods: Structured questionnaire was administered during personal interview and focus group discussion to obtain useful epidemiological information. Statistical Analysis Used: Data obtained were analyzed using Carl Pearson Chi-square at P < 0.05 level of significance. Results: The results showed that only 193 of the 578 respondents interviewed in the two communities had adequate knowledge of the cause and mode of transmission of onchocerciasis. This group knew that the disease is transmitted by the bite of infected blackflies. Other respondents (66.6%) had wrong perception about the cause and mode of transmission of the disease. The wrong perceptions observed in the communities include transmission by sexual intercourse, stepping on charms, and transmission from infected parent to offspring. The knowledge on the biting preference of the blackflies as tested among 193 respondents that were knowledgeable about the disease varied significantly (P = 0.05). Some respondents believed the fly bites in the farm (48.7%) and others believed the fly bites by the riverside (36.3%), in the village (5.2%), whereas 9.8% of the respondents believed the fly bites both on the farm and the riverside. Similarly, others believed the fly bites on the exposed legs (54.4%), hands (9.9%), and face (6.7%). Meanwhile, 29% of respondents believed the fly bites on any exposed part of the body. Conclusions: The results revealed that ignorance on the bioecology of the vector is still very high in these communities.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122066060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol use among secondary school students in Nigeria: A worrisome trend","authors":"Adewoyin Osonuga, B. Ogunmoroti, A. Osonuga, Adebayo Da'costa","doi":"10.4103/nnjcr.nnjcr_40_18","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_40_18","url":null,"abstract":"Background: Alcohol abuse is a global health problem, resulting in a spectrum of biopsychosocial and medical consequences. In recent times, there has been a surge in the number of adolescents who have been exposed to alcohol abuse and its attending consequences. This study aimed at identifying the reasons for alcohol abuse and assessed the knowledge of students about the harmful effects of alcohol. Materials and Methods: The study was a cross-sectional study involving 384 students who were selected by convenience sampling after ethical approval and consent was granted. A pretested questionnaire was administered to get basic biodata. This questionnaire also had five-scale questions to elicit other variables of interest. Data were analyzed using Microsoft Excel and SPSS. Results: 66% of respondents reported to have taken alcohol before, at ceremonies or while hanging out with friends. Alcohol caused problems with the law and family problems in about half of the respondents. Assault and high-risk sexual behaviors were not uncommon (5% and 12%, respectively). Most respondents knew of the consequences of alcohol abuse but gave reasons for taking alcohol; social media (96.2%), fun (94.8%), coping with stress of school (73.9%), and adolescence (93.8%) were common among other reasons. Conclusion: Alcohol problems are common in our secondary schools, stakeholders should be aware of this. We recommend expert support for students, especially in secondary schools, so that we can save the next generation from self-destructing.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130379455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between ABO blood group phenotypes and hypertensive disorders of pregnancy: A hospital-based cross-sectional study in Kano, North-West Nigeria","authors":"I. Mukhtar, A. Yakubu, B. Yakasai, Salisu Ahmed, Shamsuddeen Mansur","doi":"10.4103/nnjcr.nnjcr_28_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_28_19","url":null,"abstract":"Background: Hypertensive disorders of pregnancy (HDP) complicate an estimated 5%–10% of pregnancies globally. Studies have linked non-O blood group with the development of HDP, especially preeclampsia (PE). However, these reports have not been consistent. This study aimed to determine the relationship between ABO blood group and HDP among pregnant women attending antenatal clinic at Murtala Muhammad Specialist Hospital, Kano, Nigeria. Materials and Methods: Two hundred and ten pregnant women with clinically diagnosed HDP and an equal number of age-matched normotensive controls were recruited for the study. Blood pressure was measured using a mercury sphygmomanometer and a Littman's stethoscope which was positioned on the medial aspect of the right arm at sitting position. Urinalysis was performed using a urine dipstick (Medi-Test Combi 9®). ABO blood groups were determined by tile agglutination method using potent monoclonal anti-A, anti-B, and anti-D reagents (Plasmatec Lab., Bridport, UK). Data were analyzed using Statistical Package for Social Sciences version 23.0. Chi-square test of association, Student's t-test, and logistic regression were used as statistical tools, and results were presented as frequencies, percentages, mean ± standard, odds ratio (OR), and confidence interval (CI); P ≤ 0.05 was considered statistically significant. Results: The mean age of the cases and controls was 26.20 ± 6.96 and 25.90 ± 6.37, P = 0.65, respectively. The mean gestational age of the cases and controls was 32.30 ± 4.15 and 29.06 ± 4.25, P = 0.01, respectively. The mean systolic and diastolic blood pressure of the cases and controls in mmHg were 176.62 ± 32.62 and 123.08 ± 6.40, P = 0.01, and 114.20 ± 20.08 and 76.43 ± 5.07, P = 0.01, respectively. Of the 210 individuals in the HDP group (cases), 90 (42.86%) had gestational hypertension (GH), 50 (23.81%) had PE, and 70 (33.33%) had eclampsia. Type O blood group was the most common group in both cases (93 [44.3%]) and controls (98 [46.7%]). This was followed by groups A (40 [19.0%] and 45 [21.45]), B (58 [27.6%] and 53 [25.2%]), and AB (19 [9.0%] and 14 [6.7%]) for cases and controls, respectively. There was no statistically significant difference in the frequencies of ABO blood group between the cases and controls (χ2 = 1.41, P = 0.70, df = 3). Compared to type O blood group individuals, non-O blood group individuals had 1.106 times odd of developing HDP than the controls (OR: 1.106, 95% CI: 0.753–1.625, P = 0.61). Similarly, types A, B, and AB blood group individuals had 1.292, 1.492, and 1.882 times odds of developing GH compared to blood Group O and controls (OR: 1.292, 95% CI: 0.670–2.490, P = 0.45; OR: 1.492, 95% CI: 0.813–2.740, P = 0.20; and OR: 1.882, 95% CI: 0.746–4.748, P = 0.18), respectively. Equally, types A, B, and AB blood group individuals had 1.243, 0.990, and 1.699 times odds of developing PE compared to blood group O individuals and controls (OR: 1.243, 95% CI: 0.561–2.754, P = 0.59; O","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"50 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114090104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to isoniazid preventive therapy for tuberculosis among HIV patients in Kano, Nigeria","authors":"I. Jalo, U. Ibrahim","doi":"10.4103/nnjcr.nnjcr_14_19","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_14_19","url":null,"abstract":"Background: Tuberculosis (TB) is the most common opportunistic infection among human immunodeficiency virus (HIV)-infected individuals. It is a major cause of mortality among patients with HIV and poses a risk throughout the course of HIV disease. Adherence to isoniazid preventive therapy (IPT) is a critical factor that needs to be considered in scaling up services in developing countries. Objectives: The study aimed to assess adherence and associated factors to IPT among HIV patients in Kano. Methods: Using a cross-sectional study design, interviewer-administered questionnaire was used to collect information from 320 HIV patients from two comprehensive health centers (CHCs). Results: Up to two-third, 211 (65.9%) of the participants were aware of the use of isoniazid for the prevention of TB among HIV/AIDS patients, but only about half 172 (53.8%) of the respondents interviewed were currently using IPT for TB prevention. Up to 158 (89.5%) of the 172 respondents interviewed had good level of adherence to IPT and the main reasons to enhance adherence were disclosure of HIV status to partner/relatives (77.9%), adequate counseling about IPT (62.8%), and awareness of IPT for TB prevention (65.9%). Conclusion: Good level of adherence to IPT from this study implies that the need for improve strategies to ensure IPT scale up as adherence to IPT among HIV clients in Kano is optimal, but uptake remains low.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"198 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120901035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of skeletal-related events in advanced and metastatic prostate cancer patients treated with androgen deprivation therapy in a low- and middle-income country","authors":"O. Aisuodionoe-Shadrach, S. Abu","doi":"10.4103/nnjcr.nnjcr_12_17","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_12_17","url":null,"abstract":"Context: Skeletal-related events (SREs) occur in men with prostate cancer (CaP) and may result from androgen deprivation therapy (ADT). Aims: The purpose of this study was to determine the incidence of SREs in patients with CaP treated with HT while highlighting the burden of advanced and metastatic CaP in a low- and middle-income country practice. Settings and Design: Eligible cases were newly diagnosed patients with CaP seen at the University of Abuja Teaching Hospital, Abuja, Nigeria between January 2012 and December 2015 with bone metastases and treated with ADT. Subjects and Methods: Data compiled from patient's medical records showed tumor diagnosis, laboratory and radiology results. SREs included spinal cord compression, surgery to bone, pathologic fracture, and radiation to bone. Statistical Analysis Used: The data were analyzed using SPSS version 20 for windows (SPSS INC: Chicago Illinois). Results: Two hundred and nineteen cases of CaP were seen over the period of which 142 (64.8%) cases were first diagnosed as American Joint Committee on Cancer Stage IV CaP and commenced on ADT. More than half the patients on ADT were older >65 years with a mean (standard deviation [SD]) of 68.3 (±9.5) years. Serum prostate-specific antigen range was 1.4–2461.58 ng/ml with a mean (SD) of 113.7 (±288.9) ng/ml. Twenty nine patients (20.5%) had one or more SREs with spinal cord compression (19.1%), pathological fractures (1.4%), and radiotherapy to the affected bone (1.4%) being the most common SREs. ADT was orchiectomy, LHRH, anti-androgens, and complete androgen blockade (orchiectomy plus antiandrogens) in 14 (9.8%), 3 (2.1%), 44 (30.9%), and 81 (57%) patients, respectively. Conclusions: Sixty-five percent of the cases in this series were either advanced or metastatic CaP at first diagnosis majority of whom went on to orchiectomy plus antiandrogens as ADT. This lends credence not only to late presentation and increased morbidity and mortality of CaP in our environment but also to significantly low penetration of radiotherapy services and access to LHRH.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122575259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alobar holoprosencephaly in one of twin neonates","authors":"B. Idowu","doi":"10.4103/nnjcr.nnjcr_1_18","DOIUrl":"https://doi.org/10.4103/nnjcr.nnjcr_1_18","url":null,"abstract":"Holoprosencephaly (HPE) is a congenital structural anomaly of the forebrain which is often diagnosed prenatally, usually in singleton pregnancies. This is a case of alobar HPE affecting one of 19-day-old twin neonates which was only detected postnatally. The other twin was unaffected. The anomaly was not diagnosed in utero because a prenatal sonogram was not performed. This case is presented to reemphasize the need for thorough routine prenatal/obstetrics sonography. After birth, transfontanelle ultrasonography is a useful imaging modality for diagnosing this debilitating cerebral structural anomaly, but definitive classification requires cross-sectional brain imaging with computed tomography or magnetic resonance imaging.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125763175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicolegal analysis of sexual assault victims in Benin, Nigeria","authors":"C. Nwafor, W. Akhiwu","doi":"10.4103/NNJCR.NNJCR_18_17","DOIUrl":"https://doi.org/10.4103/NNJCR.NNJCR_18_17","url":null,"abstract":"Aim: The aim of this study, done in a police clinic, was to understand sexual assault (SA) victim characteristics. Subjects and Methods: All SA cases seen at the Police Clinic, Benin City, Edo State, Nigeria, were retrospectively reviewed. Results: A total of 146 cases were seen involving 144 females and 2 males. Age group of 11–15 years was mostly affected (37%). The majority of SA victims (72.6%) had no sexual activity before the assault. In 95.9% of cases, no contraceptive was used. The perpetrators were known in 52.7% of cases, and most of them (20.5%) were cotenants. There was penovaginal penetration in 91.8% of situations, with verbal threats been the most common means of subjugation. About 76.9% of SA occurred during the daytime. The hymen in 56.2% of cases showed signs of fresh injury and, in 17.9% of cases, it was intact. Seminal acid phosphatase was seen in 29.6% of cases. Conclusion: SA victims should present very early so that adequate evidence will be collected. Modern diagnostic kits including DNA profiling are needed so that perpetrators can be convicted beyond doubt, while psychological care of victims should be included in medical care.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123873477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postincision wound infiltration with bupivacaine versus pethidine for postoperative pain relief following myomectomy under spinal anesthesia","authors":"Uche C Jaja, F. Amadasun, Idehen Osazuwa Hanson","doi":"10.4103/NNJCR.NNJCR_27_18","DOIUrl":"https://doi.org/10.4103/NNJCR.NNJCR_27_18","url":null,"abstract":"Context: Bupivacaine is commonly used agent for wound infiltration because of its local anesthetic effect. However, pethidine an opioid has both local anesthetic and systemic analgesic effect. The combined analgesic effect of pethidine may be superior to bupivacaine that has only a local anesthetic effect. Few studies have however supported the superiority of pethidine over bupivacaine for wound infiltration. Aims: The aim of this study is to evaluate the analgesic effect of pethidine in comparison with bupivacaine wound infiltration for postoperative pain control in nonparturients scheduled for myomectomy under spinal anesthesia. Setting and Design: This study is a prospective, randomized, double-blinded control trial of the analgesic efficacy of plain bupivacaine versus pethidine for patients scheduled for myomectomy under spinal anesthesia in a Tertiary Healthcare center in Nigeria. Subjects and Methods: Seventy-six American Society of Anesthesiologists 1 and 11 patients billed for myomectomy using spinal anesthesia were randomized into two groups. Group bupivacaine had wound infiltration with 50 mg isobaric bupivacaine at a concentration of 0.25%. Group pethidine had 1 mg/kg pethidine. In the ward, pain was assessed at various intervals at rest and on coughing using the numerical rating scale (NRS) pain assessment tool and the time of the first analgesic request. Statistical Analysis: NRS scores were presented as median with interquartile range, Continuous variables such as duration of analgesia and total analgesic consumption were analyzed using the unpaired Student's t-test. Results: The pethidine group had a longer time to first analgesic request, lower pain scores and a higher level of satisfaction. Conclusion: This study showed that postincision wound infiltration with pethidine at 1 mg/kg as a component in multimodal analgesia is more effective than 0.25% bupivacaine in the management of postmyomectomy pain.","PeriodicalId":261902,"journal":{"name":"New Nigerian Journal of Clinical Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116480198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}