Medical Biological Science and Engineering最新文献_第5页

Role of coronary CT angiography in anomalous high take-off of right coronary artery with ST elevation myocardial infarction: a case report 冠状动脉CT血管造影在右冠状动脉异常高起飞合并ST段抬高型心肌梗死中的作用1例

Medical Biological Science and Engineering Pub Date : 2021-07-31 DOI: 10.30579/mbse.2021.4.2.111

Hyun Kuk Kim, Sung Soo Kim, Y. Ki, D. Choi, K. Park

引用次数: 0

A short review of history and technical advances in quantitative neuromuscular monitoring devices 简要回顾定量神经肌肉监测装置的历史和技术进展

Medical Biological Science and Engineering Pub Date : 2021-07-31 DOI: 10.30579/mbse.2021.4.2.83

Wonjin Lee, K. Jung

{"title":"A short review of history and technical advances in quantitative neuromuscular monitoring devices","authors":"Wonjin Lee, K. Jung","doi":"10.30579/mbse.2021.4.2.83","DOIUrl":"https://doi.org/10.30579/mbse.2021.4.2.83","url":null,"abstract":"Corresponding author Ki Tae Jung Department of Anesthesiology and Pain Medicine, Chosun University Hospital, 365 Pilmun-dearo, Donggu, Gwangju 61453, Korea Tel: +82-62-220-3223 Fax: +82-62-223-2333 E-mail: mdmole@chosun.ac.kr ORCID: https://orcid.org/0000-0002-2486-9961 Anesthetic procedures using a neuromuscular blocking drug (NMBD) always have a potential risk of residual neuromuscular block (RNMB) associated with serious respiratory complications despite the use of reversal agents. Due to the risk of RNMB, neuromuscular monitoring is a very important tool for assessing patient safety. Recently, the importance of quantitative neuromuscular monitoring has been highlighted because of the advent of sugammadex, which determines dosage based on the degree of NMB. Neuromuscular monitoring, which has been used clinically since the 1970s, is an appropriate method for assessing the level of neuromuscular blockade (NMB) after the use of a NMBD during anesthesia. Although the basic principles have not changed considerably, recent technical advances in neuromuscular monitoring devices can help anesthesiologists with convenient quantitative neuromuscular monitoring to accurately evaluate the levels of NMB, choose an appropriate NMBD, and avoid RNMB. The recently released electromyography-based devices provide more accurate values than acceleromyography (AMG). Although AMG has a problem with overestimation, modern AMG devices with new three-dimensional technology overcome this limitation. Anesthesiologists should increase their knowledge of neuromuscular mechanisms and monitoring, including how to use the latest device for proper neuromuscular monitoring and patient safety. In this review, we have explored the short history of neuromuscular monitoring devices and the latest trends in technology development.","PeriodicalId":259565,"journal":{"name":"Medical Biological Science and Engineering","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124923791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tension pneumothorax and pulmonary embolism during neurosurgery: a case report 神经外科中的张力性气胸和肺栓塞1例

Medical Biological Science and Engineering Pub Date : 2021-01-31 DOI: 10.30579/MBSE.2021.4.1.48

Doosik Kim, Ho Chul Lee, S. Ryu, Ju Deok Kim

引用次数: 0

Effect of intravenous fluid warming devices on intraoperative core temperature during maintenance fluid therapy: a prospective randomized controlled trial 一项前瞻性随机对照试验:维持液体治疗期间静脉液体加热装置对术中核心温度的影响

Medical Biological Science and Engineering Pub Date : 2021-01-31 DOI: 10.30579/MBSE.2021.4.1.10

Jeong-Wook Park, K. Jung, Bo Hyun Jang, Sang Hun Kim

{"title":"Effect of intravenous fluid warming devices on intraoperative core temperature during maintenance fluid therapy: a prospective randomized controlled trial","authors":"Jeong-Wook Park, K. Jung, Bo Hyun Jang, Sang Hun Kim","doi":"10.30579/MBSE.2021.4.1.10","DOIUrl":"https://doi.org/10.30579/MBSE.2021.4.1.10","url":null,"abstract":"Background: We investigated the effects of intravenous fluid warmers on intraoperative core temperatures at low flow rates during the maintenance fluid therapy. Methods: We conducted a prospective, non-blinded, randomized controlled trial in 99 patients, scheduled for elective spinal fusion surgery with more than 3 hours of general anesthesia. They were randomly distributed into groups using Mega Acer Kit (group M; n=30), Ranger (group R; n=32), or ThermoSens (group T; n=32). The infused flow rate of the fluid was determined as one-third of the preoperative fluid deficit (4-2-1 rules) during fasting times, and the third space loss during surgery (2 mL/kg), per hour. The primary outcome was intraoperative final and lowest esophageal temperature (T eso _ Final, lowest T eso ). Results: T eso _Final, lowest T eso , and intraoperative T eso were not significantly different between groups (p=0.512, and p=0.393, p=0.066, respectively). However, the temperature change from baseline T eso to T eso _Final was significantly different between the groups (p=0.044), which of group M were significantly lower than group T (p=0.033). After adjustment with baseline T eso , the differences of least squares means showed the significant differences between groups M and T at 2.5 hours (p=0.020) and 3 hours (p=0.006). Conclusions: The Mega Acer Kit, Ranger, and ThermoSens have a similar effect on intraoperative core temperatures with the low flow rates, but The Mega Acer Kit is more effective at controlling core temperature than the ThermoSens if the fluid infusion time is over 2.5 hours.","PeriodicalId":259565,"journal":{"name":"Medical Biological Science and Engineering","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124248681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ticagrelor does not affect left ventricular remodeling following acute myocardial ischemia 替格瑞洛不影响急性心肌缺血后左心室重构

Medical Biological Science and Engineering Pub Date : 2021-01-31 DOI: 10.30579/MBSE.2021.4.1.34

Hyun Kuk Kim, K. Lim, Sung Soo Kim, Joo-Young Na

{"title":"Ticagrelor does not affect left ventricular remodeling following acute myocardial ischemia","authors":"Hyun Kuk Kim, K. Lim, Sung Soo Kim, Joo-Young Na","doi":"10.30579/MBSE.2021.4.1.34","DOIUrl":"https://doi.org/10.30579/MBSE.2021.4.1.34","url":null,"abstract":"Despite ticagrelor’s proven superiority to clopidogrel in treating patients with acute coronary syndrome, it is unclear whether its actions are mediated by antiplatelet inhibition or by some other pleotropic effect. In this study, we used a porcine model of acute myocardial infarction (AMI) to evaluate the efficacy of ticagrelor administered at a similar level of platelet inhibition to that seen with clopidogrel. Twenty pigs were grouped according to the P2Y12-receptor inhibitors (ticagrelor or clopidogrel). Platelet inhibition was monitored by measuring adenosine diphosphate - induced platelet aggregation. A chronic ischemic heart model was artificially generated by embolization of the middle left anterior descending coronary artery. Animals received a maintenance dose of the antiplatelet agents. Two-dimensional echocardiography was performed on the surviving animals 2 weeks later. Both 180 mg ticagrelor and 600 mg clopidogrel exerted a significant and consis-tent antiplatelet effect showing platelet aggregation inhibition of 50.7±22.9% and 45.5±21.0%, respectively, p=0.614), which persisted for up to 2 weeks. However, no significant differences were observed in ventricular arrhythmia (40% vs. 50%, respectively; p=0.886). The ejection fraction measured 2 weeks after surgery was 44.6±7.4% in the ticagrelor group and 36.9±5.7% in the clopidogrel group (p=0.091). In a chronic ischemic heart failure model with a similar level of platelet inhibition, ticagrelor was no better than clopidogrel in reducing mortality and improving cardiac function.","PeriodicalId":259565,"journal":{"name":"Medical Biological Science and Engineering","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131305389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Presenting as Suspected Cervical Osseous Metastasis : A Case Report and Literature Review 弥漫性硬化型甲状腺乳头状癌疑似颈椎骨转移一例报告及文献复习

Medical Biological Science and Engineering Pub Date : 2020-11-12 DOI: 10.21203/rs.3.rs-103081/v1

A. Chong, Kweon-cheon Kim, Y. Kim, R. Hong

引用次数: 0

Pericardial effusion complicated by percutaneous central venous catheterization treated with pericardial window in a very low birth weight infant 心包积液合并经皮心包窗置管治疗1例极低出生体重儿

Medical Biological Science and Engineering Pub Date : 2020-07-31 DOI: 10.30579/mbse.2020.3.2.36

B. Lee, C. So, Seung Hyun Lee, S. Yu

引用次数: 0

Opioid-induced hyperalgesia after implantation of intrathecal morphine pump: a case report 鞘内吗啡泵植入后阿片类药物致痛觉过敏1例

Medical Biological Science and Engineering Pub Date : 2020-07-31 DOI: 10.30579/mbse.2020.3.2.47

S. Yoon, Rakmin Choi, Jaedo Lee, Jongchan Won, Bousung Lee, K. Lee, Dongseok Kim, Jaeyoung Yang

引用次数: 0

Videolaryngoscope-guided intubation without neuromuscular blockade in a patient with Huntington’s disease 视频喉镜引导下无神经肌肉阻滞插管治疗亨廷顿氏病1例

Medical Biological Science and Engineering Pub Date : 2020-07-31 DOI: 10.30579/mbse.2020.3.2.56

Hyun Young Lee, K. Jung, S. Cho, Sang Hun Kim

{"title":"Videolaryngoscope-guided intubation without neuromuscular blockade in a patient with Huntington’s disease","authors":"Hyun Young Lee, K. Jung, S. Cho, Sang Hun Kim","doi":"10.30579/mbse.2020.3.2.56","DOIUrl":"https://doi.org/10.30579/mbse.2020.3.2.56","url":null,"abstract":"Huntington’s disease (HD) has a risk of potential perioperative complications such as aspiration, drug interactions with anesthetics, agitation, psychosis, shivering, and spasms. Thus, inexperienced anesthesiologists may face challenges in the management of HD patients. A 54-year-old man with HD was scheduled to undergo open reduction and internal fixation of an intertro-chanteric femur fracture. We successfully performed videolaryngoscope-guided intubation after propofol sedation and oral topical anesthesia, as awake fibreoptic bronchoscopy-guided intubation had failed because of noncooperation and choreiform movements. Total intravenous anesthesia was maintained with propofol and remifentanil infusion, and intraoperative neuromuscular block was controlled with rocuronium and sugammadex successfully, without any postoperative complications. His psychotropic medications were restarted from the morning of postoperative day 1. Videolaryngoscope-guided intubation, total intravenous anesthesia, use of rocuronium and sugammadex, and re-administration of psychotropic medication as soon as possible form one of the successful regimens for HD patients.","PeriodicalId":259565,"journal":{"name":"Medical Biological Science and Engineering","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134255917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Papain-like 2 protease of coronavirus and innate immune response 冠状病毒木瓜样2蛋白酶与先天免疫反应

Medical Biological Science and Engineering Pub Date : 2020-07-31 DOI: 10.30579/mbse.2020.3.2.31

Y. Jeon

引用次数: 1