Videolaryngoscope-guided intubation without neuromuscular blockade in a patient with Huntington’s disease

Hyun Young Lee, K. Jung, S. Cho, Sang Hun Kim
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Abstract

Huntington’s disease (HD) has a risk of potential perioperative complications such as aspiration, drug interactions with anesthetics, agitation, psychosis, shivering, and spasms. Thus, inexperienced anesthesiologists may face challenges in the management of HD patients. A 54-year-old man with HD was scheduled to undergo open reduction and internal fixation of an intertro-chanteric femur fracture. We successfully performed videolaryngoscope-guided intubation after propofol sedation and oral topical anesthesia, as awake fibreoptic bronchoscopy-guided intubation had failed because of noncooperation and choreiform movements. Total intravenous anesthesia was maintained with propofol and remifentanil infusion, and intraoperative neuromuscular block was controlled with rocuronium and sugammadex successfully, without any postoperative complications. His psychotropic medications were restarted from the morning of postoperative day 1. Videolaryngoscope-guided intubation, total intravenous anesthesia, use of rocuronium and sugammadex, and re-administration of psychotropic medication as soon as possible form one of the successful regimens for HD patients.
视频喉镜引导下无神经肌肉阻滞插管治疗亨廷顿氏病1例
亨廷顿氏病(HD)有潜在的围手术期并发症的风险,如误吸、药物与麻醉剂的相互作用、躁动、精神错乱、颤抖和痉挛。因此,经验不足的麻醉师在治疗HD患者时可能面临挑战。一例54岁男性HD患者计划行股骨粗隆间骨折切开复位内固定。在异丙酚镇静和口服表面麻醉后,我们成功地进行了视频喉镜引导下的插管,因为清醒纤维支气管镜引导下的插管由于不配合和舞蹈样运动而失败。异丙酚和瑞芬太尼输注维持全静脉麻醉,术中罗库溴铵和糖马德控制神经肌肉阻滞成功,无术后并发症。术后第1天上午起重新给予精神药物治疗。视频喉镜引导下插管、全静脉麻醉、使用罗库溴铵和糖马德,并尽快重新给予精神药物治疗是治疗HD患者的成功方案之一。
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