C. Heckman, M.D. Johnson, A. Hyngstrom, E. Perreault
{"title":"Mapping 3D sensory inputs onto spinal interneurons","authors":"C. Heckman, M.D. Johnson, A. Hyngstrom, E. Perreault","doi":"10.1109/IEMBS.2003.1280999","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1280999","url":null,"abstract":"Extracellular recordings of 43 spinal interneurons were performed in the decerebrate cat while its hindlimb was manipulated in 3 dimensional space with a 6-degree of freedom robotic arm. Internal/external rotations, toe in/toe out and flexion/extension movements were performed about the ankle joint. Peripheral nerve stimulation was used to categorize cells by field potential threshold into gr Ila and gr II types. 80% (16/20) of the gr la cells showed firing frequency changes to less than half of the rotations imposed by the robot and only 20% to more than half. 39% (9/23) of the gr II cells showed responses to less than half of the imposed movements and 61% (14/23) of the gr II cells responded to more than half of the imposed movements.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127375745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stretch reflex gain and threshold changes as a function of elbow stretch velocity in hemiparetic stroke","authors":"J. Dewald, B. Schmit","doi":"10.1109/IEMBS.2003.1279609","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1279609","url":null,"abstract":"The main emphasis of this study is to determine the effect of stretch velocity on stretch reflex gain and threshold during elbow extension in the paretic upper limb of 13 hemiparetic stroke subjects. Ten velocities ranging from 6 to 150/spl deg//s were applied in random fashion. The resulting reflex torques were subjected to two different quantitative approaches following subtraction of passive torques obtained at the 6/spl deg//s velocity to determine the reflex threshold and gain. Both approaches determined changes in reflex threshold and gain as a function of stretch velocity in all subjects tested. The relative effects of threshold versus gain changes on stretch reflex induced flexion torques were tested for a 60/spl deg//s increase in stretch velocity from 45/spl deg/to 105/spl deg//s. In all but one of the 13 subjects the effect of reflex gain became the predominant contributor to the reflex torque before the end of the stretch. The neurophysiological and clinical implications of these findings are discussed in the paper.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125286795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiuquan Ji, Jingfei Ma, M. Aref, E. Wiener, Zhi-Pei Liang
{"title":"An improved MRI method for dynamic contrast-enhanced imaging of tumors","authors":"Xiuquan Ji, Jingfei Ma, M. Aref, E. Wiener, Zhi-Pei Liang","doi":"10.1109/IEMBS.2003.1279733","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1279733","url":null,"abstract":"Acquiring high-resolution dynamic images is desirable but often technically challenging in contrast-enhanced tumor imaging due to the limited data acquisition speed. This paper presents an improved Magnetic Resonance Imaging (MRI) method for dynamic contrast-enhanced imaging of tumors, which involves a new data acquisition scheme and a reconstruction algorithm using a generalized-series model. Simulation results using phantom and real tumor MRI imaging data show that the method can provide significant improvements in spatiotemporal resolution over previous methods such as Keyhole.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131830648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Perreault, V. Ravichandran, C. Heckman, T. Sandercock
{"title":"Muscle contributions to limb stiffness and stability in three dimensions","authors":"E. Perreault, V. Ravichandran, C. Heckman, T. Sandercock","doi":"10.1109/IEMBS.2003.1279594","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1279594","url":null,"abstract":"Successful task completion requires strength to counter external forces acting on a limb and stability to maintain limb posture. However, these simultaneous requirements can be at odds with each other as reaction forces directed towards the joints can interact with limb geometry to reduce limb stability. Net stability is due to these external force effects combined with the stability provided by muscles resisting those forces. The goal of this study was to quantify the contributions of cat hindlimb muscles to the 3D force generation and stability properties of the entire limb. Our hypothesis is that anti-gravity extensors must be co-activated with flexors to counter the destabilizing effects of the ground reaction forces directed towards the joints. Data were collected during three experimental conditions: passive, electrical stimulation of the triceps surae on its own, and in conjunction with the hamstrings. We found that the hamstrings muscle group, a leg extensor, destabilized hindlimb posture. These instabilities could be countered by simultaneous co-contraction of the triceps surae muscle group, which had a net ground reaction force in flexion direction. These initial results support our hypothesis that muscles generating downward forces (leg extensors) decrease limb stability.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115066352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Reddy, Yi-Heng Li, T. Pham, G. Taffet, L. Michael, M. Entman, C. Hartley
{"title":"Indices of aortic stiffness in mice","authors":"A. Reddy, Yi-Heng Li, T. Pham, G. Taffet, L. Michael, M. Entman, C. Hartley","doi":"10.1109/IEMBS.2003.1279605","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1279605","url":null,"abstract":"Ascending aortic input impedance spectra and pressure augmentation index was determined in young (8-month) and old (29-month) mice to see if arterial stiffening occurred with age in mice as it does in humans. Pressure and blood velocity signals measured simultaneously from the same location in the ascending aorta of a mouse were used to determine input impedance spectra (DC-10 harmonics). The first minimum of the impedance modulus shifted from the 2nd harmonic in young mice to the 4th harmonic in old mice. Characteristic impedance (estimated as average of 2nd to 10th harmonic) was significantly higher in old mice (mean/spl plusmn/SEM, 471/spl plusmn/62 vs. 299110 dynes-s/cm/sup 3/, p<0.05). Pulse pressure and augmentation index, determined from the aortic pressure signals were also higher in old mice: pulse pressure (42/spl plusmn/2.2 vs. 29/spl plusmn/4.9 mmHg, p<0.05) and augmentation index (37/spl plusmn/5 vs. 14/spl plusmn/2 %, p<0.005). These results are similar to the findings reported in humans and confirm that mice may be used as models of age-related vascular stiffening.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133884457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Motor unit action potential counts in surface electrode array EMG","authors":"P. Zhou, Z. Erim, W. Rymer","doi":"10.1109/IEMBS.2003.1280143","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1280143","url":null,"abstract":"The number of motor unit action potentials (MUAPs) appearing in the surface electromyogram (EMG) signal offers potentially valuable information about both motor unit recruitment and firing rates. Estimates of the numbers of MUAPs are likely to be a more accurate reflection of the neural command to muscle than are current EMG quantification methods. In this paper, we describe a method to estimate the number of MUAPs present in the surface EMG signals. The four-step procedure for MUAP counting takes advantage of the high selectivity and resolution of a two dimensional surface electrode array recording system . We illustrate the performance of the method of MUAP counting from surface EMG recordings at different contraction levels.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"98 1-2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114027397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.C. Slaboda, J. Boston, T. Rudy, S. Lieber, D. M. Rasetshwane, D. Weiner
{"title":"Effects of pain on shoulder jerk in elderly subjects during repetitive lifting","authors":"J.C. Slaboda, J. Boston, T. Rudy, S. Lieber, D. M. Rasetshwane, D. Weiner","doi":"10.1109/IEMBS.2003.1279732","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1279732","url":null,"abstract":"The purpose of this study was to determine if jerk, (rate of change of acceleration) differs in elderly control and CLBP patients during a lifting task. Jerk was calculated for the shoulder trajectory, since shoulder motion depends on motion at both the hips and knees. To reduce noise, Woltring's GCV hepatic spline was fitted to the data and derivatives were calculated through differentiation of the spline coefficients. A root mean square (rms) measure of jerk was used for comparison. The rms jerk values for the lifts were designated as early, middle or late based on the number of repetitions completed by the subject, and a repeated measures analysis of variance allowed testing for changes over time during the task. Lift duration was also analyzed. Significant group differences were found for lift duration and rms jerk, with controls lifting faster and generating greater values of jerk than CLBP patients. Changes over time were also observed in which lift duration decreased and jerk increased with task time. A group by time interaction occurred for lift duration but not for jerk. In general, patients had slower lifts with lower jerk values than controls, suggesting that pain impacts lifting style.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114259944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Izzetoglu, S. Bunce, M. Izzetoglu, B. Onaral, K. Pourrezaei
{"title":"fNIR spectroscopy as a measure of cognitive task load","authors":"K. Izzetoglu, S. Bunce, M. Izzetoglu, B. Onaral, K. Pourrezaei","doi":"10.1109/IEMBS.2003.1280883","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1280883","url":null,"abstract":"Functional near infrared (fNIR) sensor measures hemodynamic changes in the cortex using a portable, safe, affordable and negligibly intrusive NIR based optical brain imaging system. We hypothesize that there is a positive correlation between blood oxygenation in the relevant areas of dorsolateral prefrontal cortex and cognitive effort defined as attention and working memory. In this paper, we present the employment of the fNIR sensor to assess the cognitive state of the user. The paper also introduces the experimental setup and analysis of the fNIR data acquired from the forehead during a video-game like task namely, \"Warship Commander Task\" (WCT). In the WCT, the primary task is air warfare management. While performing the air warfare task, task difficulty and task load are manipulated by changing the number of tracks per wave and the number of more difficult \"yellow\" tracks. We explored in this paper, the correlation between cognitive task load, the subject's performance and dorsolateral prefrontal cortex oxygenation level changes. Our data analysis results show that fNIR blood oxygenation changes are significantly sensitive to wave size (task load) changes.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115461607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proposing the IOC pedagogy for Japanese higher education in the Universalize era","authors":"K. Soetanto","doi":"10.1109/IEMBS.2003.1280911","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1280911","url":null,"abstract":"During the past decade, there has been a deregulation in the Japanese higher education system caused by the mass education era. Usually, the Japanese University is difficult to get into and easy to get out of; however, recently, more universities have become more easy to get in and easy to get out of, because of the mass education era and decreased population of 18 years old students. The faculty has to face the less motivated students who come to class without the basic knowledge of science and engineering. Therefore, there is a need for changes in the teaching and learning system. A pilot study of an experimental design for assessing impact on changes in student motivation on the Japanese higher education system is presented. This paper will discuss the experiences over the last eight years from 1993 to 2001 in the course of digital circuit design of biomedical engineering study in the Toin University of Yokohama by using the Interactive Operational Control, IOC. The IOC technique combines innovative learning strategies, such as interactive and cooperative learning, with uses of the discipline, the role model, the presentation and the feedback. The students have reacted positively to this novel approach, which can be adapted to many others courses. The technique has been proven to be effective, shown by the students'grades. In this paper, the teaching strategy and responses of the students will be presented.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127542184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.K. Li, G. Drzewiecki, T. Barton, K. Khaw, J. Kedem
{"title":"Myocardial stunning analyzed by a single muscle fiber model","authors":"J.K. Li, G. Drzewiecki, T. Barton, K. Khaw, J. Kedem","doi":"10.1109/IEMBS.2003.1279520","DOIUrl":"https://doi.org/10.1109/IEMBS.2003.1279520","url":null,"abstract":"Mechanisms underlying myocardial stunning are yet to be clarified. We investigated this with a computer model in conjunction with experimental data obtained from canine subjects. A modified Hill's 3-element muscle model was subjected to parametric changes similar to regional ventricular measurements and perturbed by reductions in contractility and rates of activation and deactivation. Results show that many of the myocardial stunning features can be reproduced even in a single muscle fiber model.","PeriodicalId":258551,"journal":{"name":"Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128158149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}