Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005.最新文献_第2页

Image-guided multiscale statistical model to mimic random bone structure 图像引导的多尺度统计模型模拟随机骨结构

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1431980

Z. Fang, W. Sun, B. Regli

引用次数: 1

Ultrasound contrast agents targeted to malignancies: optimizing cellular attachment 针对恶性肿瘤的超声造影剂:优化细胞附着

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1431989

K. Oum, J. Vega, L. Leodore, F. Forsberg, J. Liu, D. Merton, M. Wheatley

引用次数: 0

Development of a microprocessor controlled cryosurgical system 微处理器控制冷冻手术系统的研制

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1431935

P. Flosdorf, J. Enderle

引用次数: 0

Investigating respiratory variation using a forehead reflectance pulse oximeter to identify airway obstruction for automated remote triage 使用前额反射脉搏血氧仪调查呼吸变化，以识别气道阻塞，用于自动远程分诊

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1432011

J. Chang, S. McGrath, G. Blike

引用次数: 2

Computer aided tissue engineering design for a spinal intervertebral disc 椎间盘的计算机辅助组织工程设计

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1432005

P. Evans, B. Starly, W. Sun

{"title":"Computer aided tissue engineering design for a spinal intervertebral disc","authors":"P. Evans, B. Starly, W. Sun","doi":"10.1109/NEBC.2005.1432005","DOIUrl":"https://doi.org/10.1109/NEBC.2005.1432005","url":null,"abstract":"Degeneration of the intervertebral disc with age has been shown to be a significant source of pain and discomfort in the elderly, resulting in decreased mobility and functionality of the intervertebral joints of the spine. Current treatments of disc degeneration disease have focused on the fixation of the vertebra-disc-vertebra interface by fusing the vertebra together, thus limiting and stabilizing the intervertebral motion, reducing the pain associated with degenerated disc motion. Other treatments have consisted of entirely replacing the intervertebral disc, restoring function to the spine without reducing the range of motion. However, the long term results of these two forms of treatment have been less than satisfactory, demanding a new approach to repair degenerated intervertebral discs. The approach used in this study is to develop an intervertebral disc with the mechanical characteristics necessary to function in the lumbar spine environment, while incorporating a scaffold structure into the implant design. This approach will provide a mechanically stable base structure for tissue engineering, allowing for the development of an implant with improved long term characteristics, and enhanced vertebral fixation due to the incorporation of cells into the disc structure, as compared to the currently used methods.","PeriodicalId":256365,"journal":{"name":"Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005.","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122257379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alginate encapsulation and hepatic differentiation of embryonic stem cells 藻酸盐包封与胚胎干细胞肝分化

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1431997

T. Maguire, E. Novik, R. Schloss, M. Yarmush

{"title":"Alginate encapsulation and hepatic differentiation of embryonic stem cells","authors":"T. Maguire, E. Novik, R. Schloss, M. Yarmush","doi":"10.1109/NEBC.2005.1431997","DOIUrl":"https://doi.org/10.1109/NEBC.2005.1431997","url":null,"abstract":"The emergence of cell based clinical technologies has been limited by the need for large cell masses (>10/sup 11/ cells). Embryonic stem cells are a promising solution to this cell source limitation because they are highly proliferative, renewable and pluripotent. Although many investigators have described techniques to effectively differentiate stem cells into a variety of mature cell lineages, these fall short in a number of ways including: 1) low yields of fully differentiated cells, 2) absence of large scale processing considerations and 3) ineffective downstream enrichment. Thus, a tissue culture microenvironment is required that may be modified to increase regulation of embryonic stem cell differentiation, and scaled to increase differentiated cell yield. Microencapsulation provides a vehicle for the discrete control of key cell culture parameters such as cell seeding density, rigidity, and substrate surface microarchitecture. In order to assess the feasibility of directing stem cell differentiation via microenvironment regulation, we have developed a murine embryonic stem cell (ES) alginate poly-L-lysine microencapsulation differentiation system. Our results indicate that the alginate microenvironment is biocompatible, is conductive to ES cell differentiation, and maintains differentiated cellular function. In addition, changes in alginate concentration and cell seeding density have proven effective in modulating differentiation as well as mature hepatic function.","PeriodicalId":256365,"journal":{"name":"Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005.","volume":"110 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132004253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Design of a wearable eye-gaze communication system for people with severe neuromuscular impairment 为严重神经肌肉损伤患者设计的可穿戴式眼睛注视通信系统

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1431909

C. Weaver, R. Martinez, C. Maier, C. Cerqueira, R. Foulds

引用次数: 4

Computer automated experimentation for the control and assessment of the classically conditioned eye blink response 经典条件下眨眼反应控制与评估的计算机自动实验

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1432021

B.R. Chumpitaz, S. Nazir, Y. Patel, M. Bergen

引用次数: 2

Development of a pulse oximeter analyzer for the developing world 为发展中国家开发脉搏血氧仪分析仪

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1432003

H. Deni, D. Muratore, R. Malkin

引用次数: 16

Optical assessment of apparent phase velocity: carotid-temporal photoplethysmograph flow waves in response to apnea 视相速度的光学评估:呼吸暂停反应的颈动脉-颞叶光容积脉搏波

Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005. Pub Date : 2005-04-02 DOI: 10.1109/NEBC.2005.1431969

M. Desiderio

引用次数: 0