{"title":"Cell-Free DNA Analysis for Antenatal Diagnosis","authors":"","doi":"10.1093/med/9780197533642.003.0032","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0032","url":null,"abstract":"This chapter provides a summary of a landmark study in obstetrics. How does cell-free DNA analysis compare with standard biomarker screening for prenatal diagnosis in women? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117285127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Introduction of Peanuts in Young Children","authors":"","doi":"10.1093/med/9780197533642.003.0039","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0039","url":null,"abstract":"This chapter provides a summary of a landmark analysis in pediatrics. Does early introduction of peanuts in infants lower the rate of peanut allergy? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122141956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Screening for Lung Cancer with Low-Dose Computed Tomography versus Chest Radiography","authors":"K. White","doi":"10.1093/med/9780199349937.003.0007","DOIUrl":"https://doi.org/10.1093/med/9780199349937.003.0007","url":null,"abstract":"This chapter provides a summary of a landmark study in preventive medicine. Is screening for lung cancer with a low-dose CT scan effective? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123097349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer Risk from Pediatric Computed Tomography","authors":"Christoph I. Lee","doi":"10.1093/med/9780197533642.003.0042","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0042","url":null,"abstract":"This chapter provides a summary of a landmark study in radiology. How much radiation do children receive from computed tomography and what is the cancer risk from this radiation exposure? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114638013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statins for Primary Cardiovascular Disease Prevention","authors":"","doi":"10.1093/med/9780197533642.003.0011","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0011","url":null,"abstract":"This chapter provides a summary of a landmark study in internal medicine. Are statins effective among patients without a history of cardiovascular disease? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130652243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Meta-Analysis on the Role of Aspirin in the Primary Prevention of Cardiovascular Disease","authors":"","doi":"10.1093/med/9780197533642.003.0003","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0003","url":null,"abstract":"This chapter provides a summary of a landmark meta-analysis in preventive medicine. Is aspirin effective for the prevention of cardiovascular disease in apparently healthy adults? Starting with that question, it describes the basics of the analysis, including funding, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124700142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Induction of Labor at 39 Weeks","authors":"","doi":"10.1093/med/9780197533642.003.0030","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0030","url":null,"abstract":"This chapter provides a summary of a landmark study in obstetrics. What are the pros and cons of labor induction in women at 39 weeks gestation? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116272657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of Stable Coronary Disease","authors":"","doi":"10.1093/med/9780197533642.003.0013","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0013","url":null,"abstract":"This chapter provides a summary of a landmark study in internal medicine. Should patients with stable coronary artery disease (CAD) be managed initially with medical therapy versus percutaneous coronary intervention (PCI)? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125989699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endovascular Therapy for Acute Ischemic Stroke","authors":"Matthew D. Kalp, D. Hwang","doi":"10.1093/med/9780197533642.003.0045","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0045","url":null,"abstract":"This chapter provides a summary of a landmark study in neurology. Is intraarterial treatment effective for an acute ischemic stroke? Starting with this question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127064256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pre-Exposure Prophylaxis to Prevent HIV Infection","authors":"","doi":"10.1093/med/9780197533642.003.0018","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0018","url":null,"abstract":"This chapter provides a summary of a landmark study in internal medicine. Is pre-exposure prophylaxis effective for preventing the transmission of HIV? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133575549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}