{"title":"Early Palliative Care in Non-Small-Cell Lung Cancer","authors":"F. Hodi, S. O'Day","doi":"10.1093/med/9780197533642.003.0049","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0049","url":null,"abstract":"This chapter provides a summary of a landmark study in systems-based practice. Can early palliative care improve the quality of life of patients with metastatic non-small-cell lung cancer (NSCLC)? Also, what is the impact of early palliative care on survival? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"19 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124318449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early versus Delayed Initiation of Antiretroviral Therapy in Patients with HIV","authors":"","doi":"10.1093/med/9780197533642.003.0017","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0017","url":null,"abstract":"This chapter provides a summary of a landmark study in internal medicine. At what CD4+ count should antiretroviral therapy be initiated in asymptomatic patients with HIV? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"242 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114325027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carotid Endarterectomy for Asymptomatic Carotid Stenosis","authors":"G. Hankey","doi":"10.1093/med/9780197533642.003.0025","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0025","url":null,"abstract":"This chapter provides a summary of a landmark study in surgery. Is carotid endarterectomy (CEA) beneficial in asymptomatic patients with severe carotid stenosis? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116831919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Heijer, F. Lijn, W. J. Niessen, Monique M.B. Breteler
{"title":"Postmenopausal Hormone Therapy","authors":"T. Heijer, F. Lijn, W. J. Niessen, Monique M.B. Breteler","doi":"10.1093/med/9780197533642.003.0004","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0004","url":null,"abstract":"This chapter provides a summary of a landmark study in preventive medicine. Should postmenopausal women take combined hormone therapy for the prevention of cardiovascular disease and fractures? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133341267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Imaging for Back Pain in Older Adults","authors":"Christoph I. Lee","doi":"10.1093/med/9780197533642.003.0040","DOIUrl":"https://doi.org/10.1093/med/9780197533642.003.0040","url":null,"abstract":"This chapter provides a summary of a landmark study in radiology. What is the impact of early imaging for back pain among older adults? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"286 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121829616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Multimodal Treatment Study of Children with Attention Deficit/Hyperactivity Disorder (MTA)","authors":"M. Hochman","doi":"10.1093/med/9780190625085.003.0007","DOIUrl":"https://doi.org/10.1093/med/9780190625085.003.0007","url":null,"abstract":"This chapter provides a summary of a landmark study in pediatrics. What is the most effective management strategy in children with attention deficit hyperactivity disorder (ADHD): (1) medication management; (2) behavioral treatment; (3) a combination of medication management and behavioral treatment; or (4) routine community care? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130054880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Trial of Arthroscopic Knee Surgery","authors":"M. Hochman","doi":"10.1093/med/9780199343560.003.0028","DOIUrl":"https://doi.org/10.1093/med/9780199343560.003.0028","url":null,"abstract":"This chapter provides a summary of a landmark study in surgery. Is arthroscopic surgery for osteoarthritis of the knee effective? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132693197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Artery Catheters in Critically Ill Patients","authors":"M. Hochman","doi":"10.1093/MED/9780199343560.003.0022","DOIUrl":"https://doi.org/10.1093/MED/9780199343560.003.0022","url":null,"abstract":"This chapter provides a summary of a landmark study in internal medicine. Do critically ill patients benefit from early insertion of a pulmonary artery catheter to help guide management? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126954514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Initial Treatment of Depression","authors":"M. Hochman","doi":"10.1093/MED/9780199343560.003.0044","DOIUrl":"https://doi.org/10.1093/MED/9780199343560.003.0044","url":null,"abstract":"This chapter provides a summary of a landmark study in psychiatry. Is pharmacotherapy or psychotherapy more effective for the treatment of depression? Also, are these treatments superior to usual depression care from primary care doctors? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130341329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-Term Impact of Bariatric Surgery","authors":"M. Hochman","doi":"10.1093/MED/9780199343560.003.0031","DOIUrl":"https://doi.org/10.1093/MED/9780199343560.003.0031","url":null,"abstract":"This chapter provides a summary of a landmark study in surgery. Does bariatric surgery in obese individuals reduce mortality? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116960298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}