Appetite最新文献

{"title":"Changes of food-cue processing in major depressive disorder patients with decreased appetite: An event-related potential study","authors":"Shanshan Lin ,&nbsp;Yiwei Du ,&nbsp;Yujie Xia ,&nbsp;Cai Nan ,&nbsp;Shenhong Weng ,&nbsp;Lin Zhou ,&nbsp;Ling Xiao ,&nbsp;Gaohua Wang","doi":"10.1016/j.appet.2025.107939","DOIUrl":"10.1016/j.appet.2025.107939","url":null,"abstract":"<div><div>Appetite decrease is a common symptom in major depressive disorder (MDD). However, published research discussing the cognitive process to food stimuli in MDD patients with decreased appetite is lacking, as are objective indicators to assess their degree of appetitive loss. The current study evaluated the disparities in food-related cognition between healthy controls and MDD patients, explored the brain regions contributing to these changes, and evaluated the potential of event-related potentials for assessing appetite loss severity. A total of 149 subjects (healthy controls, n = 50; MDD patients with decreased appetite, n = 52; MDD patients without appetite change, n = 47) were included in this study. We used the Dimensional Anhedonia Rating Scale (DARS) to measure the degree of appetite decrease, and assessed their alterations in food-related cognition with the late positive potential (LPP). The standardized low-resolution brain electromagnetic tomography (sLORETA) method was used to explore the source activity of the LPP. We found the two groups of MDD patients did not differ in the disease severity, while those with appetite decrease got the lowest DARS food/drink score. And MDD patients with decreased appetite allocated fewer attentional resources to food stimuli with significantly lower LPP amplitude evoked by food in this group. Within depressed patients, LPP source activations were reduced in lingual gyrus, cuneus, inferior and middle occipital lobe, and inferior occipital gyrus in appetite-decreased patients, indicating altered occipital activity may be associated with attentional processing in MDD patients with decreased appetite. And correlation analysis revealed a moderate, positive correlation between LPP amplitude and DARS food/drink score. This study demonstrates the cognitive differences between MDD patients with appetite decrease and without appetite change, and provides a potential biomarker for evaluating the degree of appetite loss in MDD patients experiencing decreased appetite.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107939"},"PeriodicalIF":4.6,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure of family health and its association with obesity-related eating behavior and depressive symptoms: Insights from network analysis","authors":"Junxu Lin ,&nbsp;Zijuan Ma ,&nbsp;Haihui Chen,&nbsp;Haoxian Ye,&nbsp;Wei Wang,&nbsp;Weishi Lin,&nbsp;Luning Yin,&nbsp;Rui Zhang,&nbsp;Dongfang Wang,&nbsp;Yunge Fan,&nbsp;Fang Fan","doi":"10.1016/j.appet.2025.107985","DOIUrl":"10.1016/j.appet.2025.107985","url":null,"abstract":"<div><div>The health of families is inextricably linked to the health of individuals and communities, providing the foundation for their development. Family health is a multifaceted concept and has been suggested to impact individuals' obesity-related eating behavior and the alleviation of depressive symptoms. However, existing studies have not comprehensively examined the structure of family health and its' potential associations with obesity-related eating behavior and depressive symptoms. The present study employed network analysis to ascertain the most pivotal characteristics within the interdisciplinary and holistic concept of family health. In addition, this study investigated the moderating effect of family health on the association between obesity-related eating behavior and depressive symptoms, and identified the characteristics of family health that were the most strongly linked to the association.</div><div>A total of 9091 adults participated in this nationally representative study between 10 July and September 15, 2021. The participants completed self-report assessments of family health, obesity-related eating behavior, and depressive symptoms. The results of network analysis indicated that helping each other in seeking health care services when needed (such as making physician's appointments) had the highest node expected influence (1.154) within the network. The results of moderation analysis showed that family health significantly buffered the association between obesity-related eating behavior and depressive symptoms (<em>B</em> = −0.06, 95 % CI = −0.077, −0.042). Further investigation demonstrated that not trusting doctors and other health professionals in the family presented the strongest negative correlation (−0.125) with obesity-related eating behavior, and not having adequate housing in the family showed the strongest negative correlation (−0.069) with depressive symptoms. These findings provide further insight into the critical aspects of family health and its significant correlations with obesity-related eating behavior and depressive symptoms.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107985"},"PeriodicalIF":4.6,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social mobility beliefs lower preferences for genetically-modified foods","authors":"Eugene Y. Chan ,&nbsp;Najam U. Saqib ,&nbsp;Ali Gohary","doi":"10.1016/j.appet.2025.107981","DOIUrl":"10.1016/j.appet.2025.107981","url":null,"abstract":"<div><div>This multi-study investigation explores the influence of Social Mobility Beliefs (SMB) on consumer preference for genetically-modified (GM) foods. Study 1 (<em>N</em> = 500) involved a survey, while Studies 2 (<em>N</em> = 261) and 3 (<em>N</em> = 300) employed experimental manipulations of SMB. Results demonstrate that higher SMB correlate with less favorable preferences for GM foods due to a heightened importance of adhering to social norms, which include those against GM food consumption. Experimental manipulations of SMB confirmed the causal effect of SMB on lower GM food preferences, while alterations in social norms moderate the effect. These findings underscore the significant role of SMB in shaping preferences toward GM foods. Implications extend to policy-making and communication strategies aimed at fostering sustainable food consumption practices. This research contributes novel insights to the understanding of consumer behavior and its implications for sustainable production.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107981"},"PeriodicalIF":4.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring comfort food cravings during pregnancy: A cross-sectional survey study","authors":"Elizabeth Agbor Epse Muluh ,&nbsp;Jessica C. McCormack ,&nbsp;Stephanie C. McLeod ,&nbsp;Sashie Abeywickrema ,&nbsp;Jane Hooton ,&nbsp;Mike Garratt ,&nbsp;Jamin Halberstadt ,&nbsp;Mei Peng","doi":"10.1016/j.appet.2025.107983","DOIUrl":"10.1016/j.appet.2025.107983","url":null,"abstract":"<div><div>The current study explored “comfort food” cravings during pregnancy and compared them with a non-pregnant control group, focusing on the types of craved foods, their associated sensory characteristics and emotional valence. With an online questionnaire, participants were asked about their craved foods during pregnancy or in general through open-ended questions, followed by descriptions of the sensory and affective associations of these items using the Check-All-That-Apply (CATA) method. A total of 867 women participated int eh study, distributed across the pregnancy-diet group (197 pregnant women, 288 postpartum women) and control group (382 non-pregnant) took part. While a significant portion of participants in both groups reported cravings for confectionery/sweets, these cravings were less frequent in the pregnancy group (35.9 % vs. 62.0 %, <em>p &lt;</em> 0.001). Non-citrus fruits were more commonly craved during pregnancy than in the control group (29 % vs. 13 %, <em>p</em> &lt; 0.001). The sensory characteristics of cravings showed that both groups favoured ‘sweet’ and ‘salty’ foods, but the pregnancy group exhibited a marked preference for foods described as ‘cold’ (29 % vs. 13 %, <em>p</em> &lt; 0.001), while the control group preferred ‘warm’, ‘creamy’, or ‘thick’ foods. The most frequently selected descriptors for the Emotion-CATA were ‘satisfied’, ‘happy’ and ‘pleasant’ across both groups, although the control group were more likely to associate comfort foods with ‘guilty’ (19.5 % vs 11.7 %, <em>p</em> &lt; 0.001). These findings suggest potential alterations of chemosomatosensory functions associated with pregnancy and underscore the importance of understanding these cravings. Recognising the role of comfort foods on dietary choices during pregnancy can help us develop dietary strategies that can help mitigate the negative health impacts of comfort food consumption during pregnancy and highlight the importance of emotional and psychological support during this period.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107983"},"PeriodicalIF":4.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion regulation difficulties during pregnancy mediate the relationship between childhood maltreatment and emotional, external, and restraint eating.","authors":"Sara F Stein, Alison L Miller, Amy K Nuttall, G Anne Bogat, Joseph S Lonstein, Maria Muzik, Alytia A Levendosky","doi":"10.1016/j.appet.2025.107984","DOIUrl":"https://doi.org/10.1016/j.appet.2025.107984","url":null,"abstract":"<p><strong>Purpose: </strong>Childhood maltreatment is a common and severe form of stress associated with compromised functioning in women including emotion regulation difficulties and eating behaviors associated with negative health outcomes. Although pregnancy is a sensitive period for women's health, mechanisms by which childhood maltreatment may drive eating behaviors during pregnancy remain unknown. The aim of this study was to determine if emotion regulation difficulty was a mechanism by which women's childhood maltreatment leads to emotional, external, and restraint eating during pregnancy and which types of maltreatment drive these associations.</p><p><strong>Methods: </strong>Women (N = 446) were recruited during pregnancy based on experiences of pregnancy stress, including intimate partner violence. They reported on history of childhood maltreatment and emotion regulation difficulties and eating behaviors in pregnancy. We tested if emotion regulation difficulties mediated associations between childhood maltreatment and emotional, external, and restraint eating in pregnancy.</p><p><strong>Results: </strong>Maternal childhood maltreatment was associated with greater emotion regulation difficulties and, in turn, greater severity of emotional, external, and restraint eating during pregnancy. Emotional abuse and neglect were each positively associated with emotion regulation difficulties and, in turn, all three eating behaviors.</p><p><strong>Conclusions: </strong>Emotion regulation difficulties may be a mechanism by which childhood maltreatment leads to emotional, external, and restraint eating during pregnancy. Interventions should address emotion regulation difficulties in women with histories of childhood emotional maltreatment and neglect as a way to mitigate these eating behaviors in pregnancy.</p>","PeriodicalId":242,"journal":{"name":"Appetite","volume":" ","pages":"107984"},"PeriodicalIF":4.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of family characteristics on food parenting practices among parents with school-age children and adolescents: A systematic review","authors":"Syazana Shahdan,&nbsp;Suriati Sidek","doi":"10.1016/j.appet.2025.107979","DOIUrl":"10.1016/j.appet.2025.107979","url":null,"abstract":"<div><div>Family characteristics can influence parents' implementation of food parenting practices. However, with a growing body of research on family characteristics and food parenting practices, a systematic review of the related topic has yet to be found in the current literature. Hence, the study aimed to review existing studies on family characteristics and food parenting practices among parents with school-age children and adolescents. Family characteristics refer to the family background or demographics that involve race/ethnicity, family income, parents' education levels, food security, culture, acculturation, and family structure. The study used Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for the review process. The data was collected from EBSCOhost Discovery, PubMed, and Scopus databases. Forty-five relevant articles were analyzed and summarized, and the findings were presented in three themes, including (1) culture, races/ethnicities, and acculturation, (2) socioeconomic status and food security, and (3) family structure. The results showed that the family characteristics identified in this study can influence the engagement of food parenting practices among parents with school-age children and adolescents. Several issues have been addressed for the advancement of future research, which can lead to better suggestions and implementation of food parenting practices among parents. Therefore, parents can improve their food parenting experiences and enhance their children's health, growth, and development.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107979"},"PeriodicalIF":4.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome measurement instruments used to measure diet-related outcomes in infancy: A scoping review","authors":"Karen Matvienko-Sikar ,&nbsp;Moira Duffy ,&nbsp;Eibhlín Looney ,&nbsp;Reindolf Anokye ,&nbsp;Catherine S. Birken ,&nbsp;Vicki Brown ,&nbsp;Darren Dahly ,&nbsp;Ann S. Doherty ,&nbsp;Dimity Dutch ,&nbsp;Rebecca Golley ,&nbsp;Brittany J. Johnson ,&nbsp;Patricia Leahy-Warren ,&nbsp;Marian McBride ,&nbsp;Elizabeth McCarthy ,&nbsp;Andrew W. Murphy ,&nbsp;Sarah Redsell ,&nbsp;Caroline B. Terwee","doi":"10.1016/j.appet.2025.107980","DOIUrl":"10.1016/j.appet.2025.107980","url":null,"abstract":"<div><h3>Introduction</h3><div>Supporting positive diet behaviours during infancy is essential to support child health and prevent childhood obesity. How infant diet-related outcomes are measured in trials is crucial to determining intervention effectiveness. This scoping review examined what and how outcome measurement instruments are currently used to measure 13 infant diet-related outcomes from a previously developed core outcome set.</div></div><div><h3>Methods</h3><div>The databases EMBASE, MEDLINE, CINAHL and PsycINFO were searched from inception to September 2023. Eligible studies reported trials that included infants ≤1 year old and at least one diet-related outcome measurement instrument. Titles/abstracts and full texts were independently screened in duplicate. Data were narratively synthesised.</div></div><div><h3>Results</h3><div>136 studies reporting 133 trials were included. Outcome measurement instruments used included 66 questionnaires (n = 70 studies), 65 individual questions (n = 45 studies), 24 food diaries/records (n = 21 studies), 11 24-hour dietary recall (n = 11 studies), and healthcare record data (n = 6 studies). Outcome measurement instruments were predominantly self-administered by researchers in participants homes. There was a lack of reporting for some outcome measurements used.</div></div><div><h3>Conclusion</h3><div>Review findings highlight the need to improve clarity and completeness of outcome reporting. The findings also provide an important first step to address heterogeneity in measurement of infant diet-related outcomes. Consistent measurement of diet-related outcomes is needed to improve synthesis and evaluation of obesity prevention interventions.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107980"},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Hunger the Best Sauce for Unfamiliar Foods? A Study Investigating the Effect of Hunger on Young Children's Food Intake of a Familiar and Unfamiliar Fruit","authors":"Britt Fleischeuer,&nbsp;Rosalie Mourmans,&nbsp;Pauline Dibbets,&nbsp;Katrijn Houben,&nbsp;Anouk E.M. Hendriks-Hartensveld,&nbsp;Anouk J.P. van den Brand,&nbsp;Chantal Nederkoorn","doi":"10.1016/j.appet.2025.107977","DOIUrl":"10.1016/j.appet.2025.107977","url":null,"abstract":"<div><div>Sufficient fruit and vegetable intake is crucial for healthy development, yet many children fail to meet the recommended levels, partly due to food rejection. This study aimed to identify an effective, easy-to-implement strategy to increase fruit intake in children by examining the impact of hunger on the consumption of a familiar and unfamiliar fruit. Additionally, it explored the moderating role of picky eating within this relationship. A total of 177 children aged 4–6 were assigned to a hungry condition (food-deprived for 3–4 h) or a non-hungry condition (food-deprived for less than 30 min). The children were then asked to taste either a familiar fruit (apple) or an unfamiliar fruit (lychee), with up to 9 pieces available for tasting. It was hypothesized that children in the hungry condition would consume more fruit compared to those in the non-hungry condition, and that intake would be higher for the familiar fruit than the unfamiliar fruit. Additionally, the effect of hunger on intake was expected to be moderated by picky eating, with a weaker effect in children who were more picky eaters. Results from a 2x2 ANOVA showed hunger significantly increased fruit consumption, regardless of familiarity, and the familiar fruit was consumed more than the unfamiliar fruit. No interaction between hunger and fruit familiarity was found, and picky eating did not moderate the relationship between hunger, familiarity, and intake. These findings suggest that mild hunger can be an effective strategy to increase children's fruit intake, and offering fruits when children are hungry may promote healthier eating.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107977"},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Junk food or healthy food? The relationship between odor identification performance and dietary patterns among children and adolescents","authors":"Han Zhou ,&nbsp;Yi-qi Qiu ,&nbsp;Qian-wen Ma ,&nbsp;Lai-quan Zou","doi":"10.1016/j.appet.2025.107978","DOIUrl":"10.1016/j.appet.2025.107978","url":null,"abstract":"<div><h3>Purpose</h3><div>Children and adolescents with an insecure dietary pattern are at risk of experiencing adverse health effects. In general, olfactory capacity is particularly important in shaping food-flavor perception, affecting nutritious food intake, and ultimately influencing eating behaviors such as food selection, appetite, and consumption. Therefore, the present study aimed to explore the relationship between odor identification ability and dietary patterns in this population.</div></div><div><h3>Methods</h3><div>607 children and adolescents (275 boys and 332 girls) aged 6–17 years from China were recruited for this study. Odor identification performance was assessed using the Universal Sniff (U-Sniff) test, and dietary patterns were measured using the Food Frequency Questionnaire (FFQ).</div></div><div><h3>Results</h3><div>Children and adolescents who poorly behaved in the U-Sniff test exhibited a greater tendency to choose processed foods, beverages and snacks, while this tendency was mainly observed in children aged 6–8 years.</div></div><div><h3>Conclusions</h3><div>Better odor identification ability has a positive impact on children and adolescents’ choice for healthier foods in their daily dietary intake.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107978"},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing the acceptance of alternative protein sources","authors":"Mojca Stubelj,&nbsp;Erika Gleščič,&nbsp;Boštjan Žvanut,&nbsp;Klemen Širok","doi":"10.1016/j.appet.2025.107976","DOIUrl":"10.1016/j.appet.2025.107976","url":null,"abstract":"<div><h3>Introduction</h3><div>The adequate consumption of protein-rich foods is essential for optimal human growth, development and health. However, climate change threatens global food security by disrupting agriculture and food supply chains. One possible strategy to avoid this is a sustainable diet and the consumption of plant-based protein substitutes, insect-derived proteins and cultured meat.</div></div><div><h3>Methods</h3><div>The factors that could explain the (non-)acceptance of such foods in the population were investigated. The study included 458 adults who responded to our online questionnaire.</div></div><div><h3>Results</h3><div>The results of our survey showed that 66.2 % of the respondents were open to including plant-based sources in their diet. 23.1 % were willing to eat meals derived from insects and 21 % were willing to eat cultured meat. Acceptance of these alternative protein sources was found to be influenced by a number of factors, including demographics, familiarity, frequency of meat consumption and the intention to reduce meat consumption in the future. Men and people who had tried insect-based foods in the past were more favourable towards the consumption of insect-based foods and cultured meat. The regression analysis showed that the higher the level of neophobia towards food technologies and aversion to eating insects, the lower the interest in trying cultured meat. Women have a lower interest in trying cultured meat.</div></div><div><h3>Conclusions</h3><div>The consumer acceptance of new protein sources in the diet can be measured by assessing their attitudes towards such sources. This understanding can in turn facilitate the formulation of future public health strategies to create more sustainable dietary standards in the face of climate change.</div></div>","PeriodicalId":242,"journal":{"name":"Appetite","volume":"210 ","pages":"Article 107976"},"PeriodicalIF":4.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}