Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi最新文献

{"title":"[Abdominal bleeding caused by pit viper bite: a case report and literature review].","authors":"R Z Li, J Li, W H Zhao, H Xu, D Zhao","doi":"10.3760/cma.j.cn121090-20241228-00601","DOIUrl":"10.3760/cma.j.cn121090-20241228-00601","url":null,"abstract":"<p><p>Venomous snake bite is an acute systemic toxic disease, mainly manifested as: flaccid paralysis, systemic muscle lysis, coagulation disorders, bleeding, renal dysfunction, cardiac toxicity, and local tissue damage to bite segments. This article reports a rare case of spontaneous abdominal bleeding caused by a pit viper bite on the 5th day. After receiving additional anti serum injection and strengthening the correction of coagulation function,the patient's condition improved and eventually the abdominal bleeding was absorbed.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"104-106"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Perioperative coagulation management in liver transplantation: a theoretical and practical exploration].","authors":"Y Tang, J X Lyu, C J Cai","doi":"10.3760/cma.j.cn121090-20241130-00508","DOIUrl":"10.3760/cma.j.cn121090-20241130-00508","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the characteristics of changes in coagulation function in different pathophysiological states during the preoperative, intraoperative, and postoperative phases of liver transplantation, along with its corresponding monitoring and clinical management strategies, and to provide our center's experience to other medical institutions. <b>Methods:</b> By reporting and analyzing the diagnosis and treatment process of a patient with secondary liver failure after hepatectomy in the perioperative period of liver transplantation, we summarize the characteristics of coagulation function in the perioperative period of liver transplantation as well as the management strategies, taking into account the consensus of relevant domestic and international guidelines. <b>Results:</b> In this case report, the pathophysiologic mechanisms of the different stages of perioperative liver transplantation differed significantly, and the corresponding changes in coagulation function were complex and difficult to measure. The coagulation characteristics of the perioperative stages can be summarized as preoperative platelet and coagulation factor deficiencies, intraoperative hypocoagulation and hyperfibrinolysis, postoperative incomplete recovery of coagulation function, and the coexistence of the risk of hemorrhage and thrombosis throughout the entire process, which should be treated with goal-oriented transfusion of blood products, anticoagulation, and antifibrinolysis, according to dynamic changes of the coagulation system, platelet counts, thrombus-related test indexes, and the overall function of the coagulation system such as the thromboelastogram. Under the premise of dynamic monitoring of relevant indicators, appropriate and moderate treatment should be given to maintain the relative homeostasis among the three systems of coagulation promotion, anticoagulation, and fibrinolysis, which not only avoids bleeding of vital organs caused by hypocoagulation, but also reduces the risk of perioperative thrombotic complications, and accurate monitoring and individualized treatment can improve the prognosis of the patients. <b>Conclusion:</b> Coagulation management in the perioperative period of liver transplantation is complex and variable, requiring enhanced monitoring and active and effective interventions. This study provides an important reference for the perioperative diagnosis and treatment of patients with end-stage liver disease and summarizes the effective management experience.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[HELLP syndrome: a case report and literature review].","authors":"X Zhang, H B Meng, R Y Cao, L Y Cai","doi":"10.3760/cma.j.cn121090-20241130-00507","DOIUrl":"10.3760/cma.j.cn121090-20241130-00507","url":null,"abstract":"<p><p>HELLP syndrome, also known as hemolytic syndrome, elevated liver enzymes, and thrombocytopenia syndrome, is a severe pregnancy complication associated with hypertension and is associated with poor maternal and child outcomes. Although the understanding of the disease by the obstetrician has been gradually improved in the clinical work, some patients with HELLP syndrome still have difficulties and challenges in the process of clinical diagnosis and treatment due to their rapid onset and rapid progress. This paper reports a case of HELLP syndrome treated in the First Affiliated Hospital of Harbin Medical University, hoping to provide ideas for the clinical diagnosis and treatment of the literature review.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"117-119"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Esophageal rupture induced sepsis with disseminated intravascular coagulation and liver dysfunction: a case report].","authors":"J Zhang, X C Ma","doi":"10.3760/cma.j.cn121090-20241209-00548","DOIUrl":"https://doi.org/10.3760/cma.j.cn121090-20241209-00548","url":null,"abstract":"","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"125"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pregnancy complicated with antithrombin Ⅲ deficiency: a case report and literature review].","authors":"T Y Li, S S Wang, M L Zhou, Z R Zhang, B J Zhu","doi":"10.3760/cma.j.cn121090-20241126-00483","DOIUrl":"10.3760/cma.j.cn121090-20241126-00483","url":null,"abstract":"<p><p><b>Objective:</b> To report the diagnosis and treatment of a pregnant woman with antithrombin (AT) Ⅲ deficiency in pregnancy, and combine the diagnosis and treatment ideas with the literature. <b>Methods:</b> The clinical diagnosis and treatment process of one pregnant woman with AT-Ⅲ deficiency admitted to the Second Affiliated Hospital of Zhengzhou University from October 2023 to June 2024 were retrospectively analyzed. Combined with relevant literature, the effect of pregnancy with AT-Ⅲ deficiency on pregnancy outcome was summarized, and reference was provided for the formulation of anticoagulant regimen. <b>Results:</b> The patient had 3 adverse pregnancy histories and a deep venous thrombosis of the lower limbs. The AT activity fluctuated between 34% and 50% during this pregnancy. The patient received 3 transfusions of fresh frozen plasma during pregnancy and was administered low molecular weight heparin from pre-pregnancy until 24 hours before delivery. Warfarin, hydroxychloroquine, cyclosporine and methylprednisolone were added in the second trimester. The pregnancy was terminated at 35 weeks of gestation. The infant was born with a weight of 2,330 g and was transferred to the pediatric department for treatment. After 14 days, the infant was discharged. Follow-up to date has not revealed any abnormalities. <b>Conclusion:</b> Precise treatment of pregnancy with AT-Ⅲ deficiency can effectively improve pregnancy outcomes.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"40-46"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Acute myeloid leukemia with translocation t (8;16) (p11;p13) and prominent coagulation abnormalities at onset: case report and review of literature].","authors":"J W Dai, F Xue, W Liu, L Zhang, R C Yang, X F Liu","doi":"10.3760/cma.j.cn121090-20241130-00503","DOIUrl":"10.3760/cma.j.cn121090-20241130-00503","url":null,"abstract":"<p><p>Acute Myeloid Leukemia with t (8;16) (p11;p13) is a rare subtype of AML. This article presents a retrospective analysis of a 19-year-old female patient with t (8;16) (p11;p13) AML, focusing on her clinical features and treatment course, alongside a review of relevant literature. The patient was admitted due to skin ecchymosis and gastrointestinal bleeding, rapidly progressing to disseminated intravascular coagulation. Bone marrow examination revealed an abnormal blast morphology resembling early promyeloblasts, and the initial diagnosis was acute promyelocytic leukemia. However, chromosomal analysis identified the t (8;16) (p11.2;p13.3) translocation. The patient was finally diagnosed with acute monocytic leukemia. Following intensive induction chemotherapy, she achieved complete remission, but relapse occurred during consolidation therapy. The overall prognosis was poor. AML with t (8;16) (p11;p13) is relatively rare and characterized by distinct clinical and laboratory features, with a generally unfavorable prognosis. Early recognition by clinicians is crucial for appropriate management.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Coagulation dysfunction due to traumatic hemorrhagic shock: a case report].","authors":"N Luo, Y Li","doi":"10.3760/cma.j.cn121090-20241127-00486","DOIUrl":"https://doi.org/10.3760/cma.j.cn121090-20241127-00486","url":null,"abstract":"","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"120-121"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Amniotic fluid embolism combined with disseminated intravascular coagulation: a case report].","authors":"Y Yuan, W Zhang, M Tang","doi":"10.3760/cma.j.cn121090-20241227-00598","DOIUrl":"https://doi.org/10.3760/cma.j.cn121090-20241227-00598","url":null,"abstract":"","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"127-128"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Acquired FX deficiency: a case report and literature review].","authors":"J Zhang, W Liu, Y H Wang, R C Yang, L Zhang, F Xue","doi":"10.3760/cma.j.cn121090-20241130-00512","DOIUrl":"10.3760/cma.j.cn121090-20241130-00512","url":null,"abstract":"<p><p><b>Objective:</b> To introduce the clinical features, laboratory findings, diagnostic approaches, and treatment of acquired factor X deficiency. <b>Methods:</b> This study reviewed a case of primary light-chain amyloidosis with acquired factor X deficiency admitted to our hospital. The patient's clinical course and diagnostic process were described, and a literature review was conducted. <b>Results:</b> The patient, a 69-year-old male, was admitted to our hospital due to abdominal bleeding. He was diagnosed with primary light-chain amyloidosis complicated by acquired factor X deficiency. Recurrent bleeding was attributed to amyloid deposits in peripheral blood vessels and organs, which adsorbed circulating factor X, causing its sequestration in the reticuloendothelial system (e.g. the spleen) and leading to decreased factor X levels. After active hemostasis and treatment of the underlying disease, the patient was discharged. <b>Conclusion:</b> This case provides insights and a reference for the diagnosis and management of the rare clinical presentation of acquired coagulation factor deficiency.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"18-21"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Perioperative coagulation management during left ventricular assist device implantation surgery for end-stage heart failure: four cases and literature review].","authors":"H X Wang, H W Wang","doi":"10.3760/cma.j.cn121090-20241128-00488","DOIUrl":"10.3760/cma.j.cn121090-20241128-00488","url":null,"abstract":"<p><p><b>Objective:</b> Exploring the management of perioperative coagulation function in patients with end-stage heart failure undergoing left ventricular assist device implantation surgery. <b>Methods:</b> Collect clinical data of four end-stage heart failure cases who underwent left ventricular assist device implantation surgery at TEDA International Cardiovascular Hospital from September to November 2023, including surgical conditions, coagulation indicators, application of blood products and coagulation drugs, and conduct literature review. <b>Results:</b> Four patients underwent left ventricular assist device implantation surgery, as well as tricuspid valve shaping and left atrial appendage closure surgery. One patient underwent mitral valve shaping surgery, while the other underwent aortic valve replacement surgery. All patients used blood products such as platelets and cryoprecipitate during the surgery. They also used clotting drugs such as fibrinogen and recombinant human coagulation factor VIIa during surgery. After returning to the intensive care unit, all patients received oral warfarin and heparin bridged anticoagulant therapy. All patients did not experience any coagulation related complications and were discharged smoothly. Currently, all patients have a good quality of life. <b>Conclusions:</b> The coagulation management of left ventricular assist device implantation surgery for end-stage heart failure is influenced by multiple factors such as etiology and surgical impact, and The management strategy presented in this paper can serve as a reference method for reducing coagulation-related complications in clinical practice.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"47-52"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}