[Progress in hematopoietic stem cell transplantation for acute myeloid leukemia].

Q3 Medicine
X L Zhu, X J Huang, Y Wang
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引用次数: 0

Abstract

Acute myeloid leukemia (AML) is a malignant disease of myeloid hematopoietic stem/progenitor cells. Although new drugs have emerged in recent years, the status of hematopoietic stem cell transplantation (HSCT) in AML still remains irreplaceable. This article reviews the adjustment of indications for HSCT in AML, donor selection, and updates of conditioning regimens, new prevention strategies for post-transplant relapse, new targeted drugs, immunotherapy combined with HSCT to improve the prognosis of relapsed and refractory AML, and optimization of transplantation technology for elderly AML.

[造血干细胞移植治疗急性髓系白血病进展]。
急性髓系白血病(AML)是一种髓系造血干细胞/祖细胞恶性疾病。虽然近年来出现了新的药物,但造血干细胞移植(HSCT)在AML中的地位仍然不可替代。本文综述了移植适应症的调整、供体的选择和调理方案的更新、移植后复发的新预防策略、新的靶向药物、免疫治疗联合移植改善复发难治性AML预后、老年AML移植技术的优化等。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
0.80
自引率
0.00%
发文量
100
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