ACS Photonics最新文献

{"title":"","authors":"Shu Li, Xinlei Kou, Jingyao Xu, Min Gu and Jing Wang*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00658","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Zhuoshi Li, Yefeng Shu, Linpeng Lu, Jiasong Sun, Qian Shen, Peng Gao*, Piotr Zdańkowski, Maciej Trusiak*, Malgorzata Kujawinska*, Qian Chen* and Chao Zuo*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.4c02010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Keita Ikeda, Yiyang Chen, Peng Wang, Yoshiyuki Miyamoto, Takashi Taniguchi, Shinobu Onoda, Mutsuko Hatano and Takayuki Iwasaki*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.4c02490","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Gopal Verma*, Iver Brevik and Wei Li*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00525","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the Absolute Concentration of Rayleigh Particles via Interferometric Scattering Microscopy","authors":"Il-Buem Lee, Hyeon-Min Moon, Jin-Sung Park, Se-Hwan Lee, Jaewon Lee, Sung Hun Park, Seungwoo Lee, Seok-Cheol Hong, Minhaeng Cho","doi":"10.1021/acsphotonics.5c00736","DOIUrl":"https://doi.org/10.1021/acsphotonics.5c00736","url":null,"abstract":"Nanoparticles play vital roles across healthcare, electronics, and energy, where their nanoscale dimensions enable unique functionalities, such as crossing biological barriers to enhance drug delivery. However, this same small size also raises safety concerns, making accurate characterization essential, especially in biomedical applications. Traditional techniques, including dynamic light scattering and mass spectrometry, often fall short in sensitivity, resolution, and versatility. To overcome these limitations, we introduce iCOUNT (interferometric concentration observer and ultrasmall nanoparticle tracker), a method that integrates interferometric scattering (iSCAT) microscopy with deep learning-based particle detection to enable the detection and quantification of nanoparticles smaller than 50 nm (Rayleigh particles, RPs), well below the diffraction limit and in the Rayleigh regime. Our machine learning-based analysis framework facilitates automated, accurate identification and robust tracking of individual RPs from high-frame-rate iSCAT image sequences. This label-free, real-time approach yields multiple key properties of RPs, including size, diffusion coefficients, scattering contrast, and absolute concentration in aqueous environments. iCOUNT reliably detects and tracks dielectric nanoparticles as small as 20 nm in diameter, achieving high spatial and temporal resolutions. We demonstrate its performance by characterizing diverse biological Rayleigh particles, such as immunoglobulin M, simian virus 40, and DNA origami. These results validate the method’s accuracy in size and concentration measurements and uncover single-particle heterogeneity in both optical and dynamic behavior. As a noninvasive optical technique, iCOUNT addresses critical shortcomings of conventional methods and provides a powerful, generalizable platform for nanoparticle analysis in native environments, with broad implications for diagnostics, therapeutics, and nanoscience.","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"145 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Baichuan Jiang, Zhagen Miao, Yingxuan Zhao, Can Gao, Wenbin Li, Huanli Dong, Cailing Ou, Jun Li, Nannan Dou, Tingyu Ji, Zixiao Han, Xiaoru Cao, Paolo Samorì and Lei Zhang*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00576","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144355682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Long Zhang, Zhituo Chen, Gaopeng Wang, Dajian Liu, Penghui Dong, Da Lv, Haorui Liu, Yiwei Xie, Yaocheng Shi and Daoxin Dai*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00427","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Hongzhi Li, Yurong Jiang*, Suicai Zhang, Leiming Yu, Xueping Li, Xiaohui Song and Congxin Xia*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00355","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Boyi Zhou, Ran Jing, Wenjun Zheng, Xinzhong Chen, Jiacheng Sun, Zijian Zhou, Heng Wang, Lukas Wehmeier, Erdong Song, Bing Cheng, Yinan Dong, Matthew Cothrine, David Mandrus, G. L. Carr, Xu Du, Erik A. Henriksen, D. N. Basov and Mengkun Liu*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00296","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Tong Yu, Ying Luo, Jiawei Shi, Changxu Liu, Yu Luo, Stefan A. Maier, Xiaofeng Li* and Cheng Zhang*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23,"journal":{"name":"ACS Photonics","volume":"12 6","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":6.5,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.5c00379","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144424112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}