{"title":"The relation of SYNTAX score with Carotid Plaque Morphology in Patients who Undergoing Coronary By-pass Surgery","authors":"S. Aksoy, Oğuzhan Birdal, I. Yurdaışık","doi":"10.51645/khj.2021.m136","DOIUrl":"https://doi.org/10.51645/khj.2021.m136","url":null,"abstract":"Objectives: Although there are many studies assessing the relationship between carotid artery ultrasound findings and coronary artery disease, the relationship between carotid plaque types and the complexity of coronary lesions is not assessed. We aimed to examine the relationship between the SYNTAX score and carotid plaque morphology.\u0000 Patients and Methods: We retrospectively screened patients who underwent carotid Ultrasound before the coronary artery bypass graft operation between 2015 and 2020. Syntax score was calculated by two independent interventional cardiologists with online SYNTAX score calculator (www.syntaxscore.com). The lesions of carotid arteries by ultrasound were classified as fibrous, calcific and mixed plaques.\u0000 Results: A total of 407 patients were enrolled. Median age was 65 (58-71) years and 81.6% of patients were male. We used multinomial logistic regression to test the association between plaque types and syntax score. The syntax score was associated with calcified plaque both in right (odds ratio 1.04, 95% CI 1.01-1.07, p=0.006) and left internal carotid artery (odds ratio 1.04, 95% CI 1.02-1.06, p=0.004). However, the syntax score was not associated with fibrous (odds ratio 0.97, 95% CI 0.94-1.01, p=0.155 for right and odds ratio 0.99, 95% CI 0.96-1.02, p=0.759 for left carotid artery) and mixed plaque types (odds ratio 1.02, 95% CI 0.98-1.06, p=0.168 for right and odds ratio 1.00, 95% CI 0.96-1.04, p=0.791 for left carotid artery).\u0000 Conclusion: Syntax score may provide an idea for carotid plaque morphology prediction. Especially higher SYNTAX score may be a predictor of calcific carotid plaque.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126981164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatma Ukil Işıldak, Y. Yavuz, O. Savluk, N. Çine, U. Uslu
{"title":"Preoperative Albumin Level is not Associated with Acute Kidney Injury After Pediatric Cardiac Surgery: A Retrospective Cohort","authors":"Fatma Ukil Işıldak, Y. Yavuz, O. Savluk, N. Çine, U. Uslu","doi":"10.51645/khj.2021.m105","DOIUrl":"https://doi.org/10.51645/khj.2021.m105","url":null,"abstract":"Objectives: This study aimed to evaluate whether the development of acute kidney injury (AKI) was associated with preoperative albumin/prealbumin levels and other clinical features in pediatric patients who underwent open-heart surgery for congenital heart disease.\u0000 Patients and Methods: In this retrospective cohort, patients aged between 1 – 60 months who underwent open-heart surgery (complete correction surgery) with a diagnosis of congenital heart disease at the XXXXXX, between January 1, 2018 - December 31, 2020, were retrospectively included (n = 100). Patient demographics, diagnoses, surgical characteristics, and laboratory findings were recorded and analyzed.\u0000 Results: Mean age was 13.63 ± 12.05 (range 1.5 - 60) months. eGFR was decreased by more than 50% in 13% of the cases. Compared to the preoperative period, it was found that urea (24th and 48th hour) and creatinine levels increased significantly (p< 0.001, for each), and eGFR decreased significantly in the postoperative period (p< 0.001). Linear regression for eGFR value revealed that longer aortic cross-clamp time (ACCT) was associated with a greater decrease in eGFR (p= 0.046). Other variables included in the model, age (p= 0.128), gender (p= 0.358), RACHS (p= 0.865), body mass index (p= 0.862), prealbumin (p= 0.313), albumin (p= 0.806) and duration of cardiopulmonary bypass (p= 0.921) were found to be non-significant.\u0000 Conclusion: While there was no relationship between eGFR and preoperative albumin/prealbumin levels in patients who underwent cardiac surgery due to congenital heart disease, longer ACCT was found to be associated with decreased eGFR.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133898269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. A. Kara, Ergi̇n Arslanoğlu, Fatih Tomrukcu, A. A. Yılmaz, F. Yiğit, H. Ceyran
{"title":"Scimittar Syndrome; Right time to operate? and mid-term results.","authors":"K. A. Kara, Ergi̇n Arslanoğlu, Fatih Tomrukcu, A. A. Yılmaz, F. Yiğit, H. Ceyran","doi":"10.51645/KHJ.2021.M162","DOIUrl":"https://doi.org/10.51645/KHJ.2021.M162","url":null,"abstract":"Objectives: Scimitar syndrome is a combination of rare congenital cardiopulmonary anomalies\u0000 that can occur in 3% to 6% of patients with a partial abnormal venous connection. The\u0000 presence of accompanying cardiac anomalies in these patients and in cases such as severe hypoplasia of the right lung or accompanying pulmonary artery hypertension necessitate early surgery in early infancy.\u0000 Patients and Methods: 9 patients with scimitar syndrome operated on in our pediatric cardiac surgery clinic from 2012 to 2020 were retrospectively examined in our study. The ages of the patients\u0000 ranged from 1 to 47 years, with a mean of 18.11±14.44. 1 patient died and mortality was\u0000 11.11%. Of the patients, 4 were male (44.44%) and 5 were female (55.56%). Patients'\u0000 pulmonary arterial pressure ranged from 0.15 to 94 mmHg, with a mean of 39.22 ±22.49.\u0000 Results: Close to 25% scimitar vein stenosis or scimitar vein drainage occlusion has been\u0000 reported in the postoperative period, mostly in the newborn group in the literature. 2 patients had non-critical stenosis during the 3rd year follow-up despite the absence of stenosis orocclusion during the first 2 years of follow-up of 9 patients we followed. Their surgical follow-up is still ongoing since they are asymptomatic.\u0000 Conclusion: As a result, the course of the disease depends on the follow-up of the patient, the\u0000 timing of the surgery, and the quality of the anastomosis. The follow-up and treatment of\u0000 these patients will be more accurate in advanced centers experienced in scimitar surgery.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133160937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Yıldız, Yasemin Ozsahin, H. Yılmaz Ak, D. Oksen
{"title":"Isolated right ventricular noncompaction in an adult woman with severe pulmonary hypertension following at the intensive care unit","authors":"M. Yıldız, Yasemin Ozsahin, H. Yılmaz Ak, D. Oksen","doi":"10.51645/khj.2021.m148","DOIUrl":"https://doi.org/10.51645/khj.2021.m148","url":null,"abstract":"Pulmonary hypertension is defined by a mean pulmonary artery pressure ≥25 mmHg at rest, measured during right heart catheterization. Ventricular noncompaction is a genetic cardiomyopathy which mostly effects left ventricle. It is related with deterioration of myocardial embryogenesis and commonly together with other cardiac diseases (1).\u0000 Isolated ventricular non-compaction is characterized by modified morphology of myocardial wall, increased trabeculation in ventricular cavity and deep intertrabecular recesses.\u0000 A 43-year-old woman presented exercise induced dyspnea and atypical chest pain. She has not any medical history prior. On admission, her 12 lead ECG showed complete righ bundle branch block, her blood pressure was 120/80 and pulse rate 80 per minutes. Transthoracic 2D echocardiogram and magnetic resonance imaging showed dilated and hypertrophied right ventricle with non-compaction of the right ventricular apex. The systolic pulmonary arterial pressure was 80 mmHg on the Doppler echocardiography. The coronary angiography revealed normal coronary arteries. The catheterization was showed pulmonary hypertension, right ventricle non-compaction and negative pulmonary vasoreactivity testing.\u0000 Ventricular noncompaction, especially right ventricular noncompaction, complicated by severe pulmonary hypertension is exceptional. Only a few isolated right ventricular noncompaction has been reported but inclusion of pulmonary hypertesion cases are rare subsets .\u0000 Diagnosis of pulmonary hypertension may be a consequence of increased pulmonary venous pressures caused by systolic and diastolic ventricular dysfunction secondary to right ventricular noncompaction. Widespread usage of cardiac magnetic resonance imaging, may enhance visual quality and evaluation of ventricular morphology, probably this will provide prevalance increment and clinical outcome improvements. Early diagnosis would bring better results.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"295 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132755954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. E. Işık, Ergi̇n Arslanoğlu, Ö. Şavluk, H. Ceyran
{"title":"Healthcare-associated Infections in Pediatric Cardiovascular Surgery Intensive Care Unit between 2016-2020","authors":"M. E. Işık, Ergi̇n Arslanoğlu, Ö. Şavluk, H. Ceyran","doi":"10.51645/khj.2021.m125","DOIUrl":"https://doi.org/10.51645/khj.2021.m125","url":null,"abstract":"Objectives: Healthcare-associated infections are the most common problem in intensive care unit worldwide. Children with congenital heart diseases have many complications such as developmental problems, respiratory tract infections, endocarditis,pneumonia and after long-term hospital and intensive care stays and surgeries patients become vulnerable to healthcare-associated infections.\u0000 Patients and Methods: The study presents the frequency of infection, microorganisms in patients hospitalized at SBÜ Koşuyolu High Spesialization Research and Training Hospital pediatric cardiovascular surgery intensive care unit between 2016-2020.\u0000 Results: One hundred-eight HAI episodes were seen in 83 of 1920 patients hospitalized in pediatric cardiovascular surgery intensive care unit between 2016-2020.HAI rates varied between 4.8% and 7.77%. In the 5-year period,a total of 118 different microorganisms were detected.Among all microorganisms, Candida species (n: 43, 36.4%) ranked first. central line-associated bloodstream infections (CLABSI) 53 (49%), ventilator-associated pneumonia (VAP)40 (37%), surgical site infection (SSI) 8 (6.5%), catheter -associated urinary tract infection (CAUTI) 7 (6%)\u0000 Conclusion: Healthcare-associated infections are require special attention in pediatric cardiovascular intensive care units. In order to prevent, innovations such as bundle applications should be implemented as well as personnel training.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130320976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ergi̇n Arslanoğlu, K. A. Kara, F. Yiğit, Babürhan Özbek, Y. Yavuz, Fatma Ukil Işıldak, E. Tunçer, N. Çine, H. Ceyran
{"title":"Disease oriented ECMO results; specific considerations for different pathologies","authors":"Ergi̇n Arslanoğlu, K. A. Kara, F. Yiğit, Babürhan Özbek, Y. Yavuz, Fatma Ukil Işıldak, E. Tunçer, N. Çine, H. Ceyran","doi":"10.51645/khj.2021.m103","DOIUrl":"https://doi.org/10.51645/khj.2021.m103","url":null,"abstract":"Objectives: Extracorporeal membrane oxygenation (ECMO), whose use has increased with technological developments in pediatric heart surgery, is a life-saving treatment modality that is used in patients with cardiac or pulmonary insufficiency who are unresponsive to medical treatment. We investigated the effect of operation technique and cardiac morphology of patients undergoing pediatric cardiac surgery in our clinic on ECMO prognosis in this retrospective cohort study.\u0000 Patients and Methods: 70 patients in need of ECMO after pediatric heart surgery were enrolled between May 2010 and April 2020 in our clinic. 44.3% (n=31) of patients were female and 55.7% (n=39) were male. Their ages ranged from 0 to 575 months, with a mean of 32.59±147.26. RACHS-1 was 25%, RACHS-2 was 23.07%, RACHS-3 was 33.33%, RACHS-4 was 35.71%, RACHS-5 was 100%, and RACHS-6 was 50% according to the ECMO result. No statistically significant difference was found between mortality and RACHS scoring.\u0000 Results: As a consequence, scoring systems used in the evaluation and measurement of ECMO use in the pediatric age group can be deceptive.\u0000 Conclusion: We attribute this to the fact that ECMO is a complex and complicated treatment that affects all systems in general and has a lot of mechanical and physiological complications. We think that the combination of scoring systems used in these patients with other scoring methods will give more accurate results than using them alone.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125872765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ergi̇n Arslanoğlu, K. A. Kara, A. Hatemi, Berrra Zümrüt Tan, Ö. Şavluk, Fatma Ukil Işıldak, E. Tunçer, N. Çine, H. Ceyran
{"title":"The importance of gestational age as a prognostic factor on Norwood Stage 1 outcome","authors":"Ergi̇n Arslanoğlu, K. A. Kara, A. Hatemi, Berrra Zümrüt Tan, Ö. Şavluk, Fatma Ukil Işıldak, E. Tunçer, N. Çine, H. Ceyran","doi":"10.51645/khj.2021.m102","DOIUrl":"https://doi.org/10.51645/khj.2021.m102","url":null,"abstract":"Objectives: The Norwood operation performed for hypoplastic left heart syndrome (HLHS) in the neonatal period remains to be a high-risk and difficult surgical procedure. It is known that preterm birth often accompanied by low birth weight is associated with high mortality and morbidity in these patients.\u0000 Patients and Methods: The study included 54 patients who underwent the Norwood procedure in our clinic in the period between December 2012 and December 2019. Patient data were evaluated retrospectively; including gestational week, age, body weight, total bypass time, aortic cross-clamp time, extubation time, the length of stay in the intensive care unit, the length of hospital stay, and the preoperative and postoperative levels of urea, creatinine, ALT, AST, and platelet counts.\u0000 Results: The body weight of the patients ranged from 2350 to 4500 grams with an average of 3296.3±486.7 grams. The age of the patients at the time of operation ranged from 1 to 374 days with an average of 30.31±70.51 days. The comparison of patients by term pregnancies resulted in no statistically significant differences but the comparison by gestational weeks revealed a statistically significant result.\u0000 Conclusion: Preoperative risk factors affect prognosis more than the surgical technique and the treatment approach in patients with a functional single ventricle. When the gestational week was evaluated as a preoperative risk factor for its effects on the postoperative prognosis of stage 1 Norwood operation in our study, it was found that mortality decreased significantly after the 38.8th gestational week (272 gestational days).","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130601899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. A. Yılmaz, M. Üstündağ, Y. Yavuz, Fatma Ukil Işıldak, Ö. Şavluk, H. Ceyran
{"title":"Investigation of anxiety, depression and perceived caregiving burden in parents of pediatric patients undergoing open heart surgery and being followed up in intensive care","authors":"A. A. Yılmaz, M. Üstündağ, Y. Yavuz, Fatma Ukil Işıldak, Ö. Şavluk, H. Ceyran","doi":"10.51645/khj.2021.m95","DOIUrl":"https://doi.org/10.51645/khj.2021.m95","url":null,"abstract":"Objectives: This study aims to investigate the relationship between anxiety levels and perceived caregiver burden in mothers of children who had undergone Congenital Heart Disease Surgery (CHDS) and who were followed up in the intensive care unit with the surgical type and clinical variables applied.\u0000 Patients and Methods: The study was conducted with the mothers of both patient groups who underwent Palliative Surgery (PS) (n:32) or Corrective (Biventricular) Repair (CR) (n:35) in the Pediatric Cardiovascular Surgery clinic of Istanbul Koşuyolu High Specialty Educational and Research Hospital. Sociodemographic-Clinical Data Form, Beck Depression Inventory (BDI), Standardized Mini-Mental Test, State-Trait Anxiety Inventory (STAI TX I-II), and Zarit Burden Interview (ZBI) were applied to the parents.\u0000 Results: The rate of interventional birth was higher in the PS group whereas there was no difference between the PS and CR groups in terms of age, gender, birth weights, and presence of additional diseases (p: 0.001). There was no difference between maternal education levels and pregnancy duration. This difference was not significant even though the mean age of the mothers in the CR group was higher compared to the PS group. The mean STAI-S scores of the PS group (State Anxiety) were lower than the CR group, and the STAI-T scores of the PS group (Trait Anxiety) were higher. The ZBI scores were significantly higher in the PS group (p: 0.03)\u0000 Conclusion: Congenital heart diseases and surgical interventions, as a result, are a major source of distress for affected families. Mothers are mainly affected by this situation. Changes in the mental status of the caregiver may have serious adverse effects on the operated child at every stage of the disease. Caregiving in parents is perceived as a burden and increased anxiety leads to different psychiatric clinical manifestations. Therefore, it is recommended that parents of children who have undergone congenital cardiac surgery receive routine psychiatric support from the early stages of the disease.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130324239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early and Mid-term Results of Mitral Valve Repair in Patients with Degenerative Mitral Regurgitation","authors":"H. Erdem, E. Selçuk","doi":"10.51645/khj.2021.m133","DOIUrl":"https://doi.org/10.51645/khj.2021.m133","url":null,"abstract":"Objectives: In this study, we present the mid-term results of patients who underwent valve repair due to degenerative mitral valve regurgitation in the first five years of our mitral valve repair program.\u0000 Patients and Methods: In this retrospective study, all patients who were operated for degenerative mitral regurgitation by a single surgical team between 2013 and 2017 were investigated. We determined early and mid-term cumulative survival rates, repair failure and freedom from reoperation. In addition, as a specific subgroup, the results of patients under 18 years of age after mitral valve repair were investigated\u0000 Results: Mitral repair was performed in 121 of 153 degenerative mitral regurgitation patients during the study period. The overall repair rate was 79%. Mitral valve repair rate increased significantly over years. The Median follow-up time was 63 (range 10-92) months. Early mortality was 2.5% (n=3 patients). During the follow-up period, moderate-to-severe mitral regurgitation was observed in 14 (11.8%) patients, mitral valve reoperation was required in 7 (5.9%) patients. Valve repair was performed in 4 of 7 patients under the age of 18. There was no pediatric case requiring reoperation during the follow-up period (median 46 months).\u0000 Conclusion: Mid-term results of mitral valve repair in degenerative mitral valve patients are satisfactory. The success rate of repair increases in line with surgical experience.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126875902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gorkem Citoglu, S. Genç, Hacer Kamalı, F. Şengül, I. Onan
{"title":"Outcomes of Partial Atrioventricular Septal Defect Repair in Children","authors":"Gorkem Citoglu, S. Genç, Hacer Kamalı, F. Şengül, I. Onan","doi":"10.51645/KHJ.2021.M91","DOIUrl":"https://doi.org/10.51645/KHJ.2021.M91","url":null,"abstract":"Objectives: Repair of the partial atrioventricular septal defect (pAVSD) has an excellent survival but reoperation is still an issue. Left atrioventricular (AV) valve regurgitation (LAVVR) is the most common reason for reoperation. This study aimed to retrospectively analyze the results of patients undergoing pAVSD repair to determine the morbidity and mortality rates.\u0000 Patients and Methods: Follow-up data of a total of 25 patients younger than 18 years of age, who underwent pAVSD at our centre within the period from 2011 to 2019, were obtained from hospital records. The incidence of Down syndrome, death, complications and reoperation rates were analyzed.\u0000 Results: Mean age at operation was 4.64 years. Preoperative LAVVR grade was found to be relatively high in patients who underwent surgery at an older age (p<0.05). Two patients (8%) had Down syndrome. Follow-up ranged from two months to 96 months (mean: 33.48 months). There was no perioperative mortality. Arrhythmia were observed in four patients (16%) after the operation. One patient (4%) had complete AV block requiring permanent pacemaker implantation. The rate of postoperative LAVVR was observed to increase as the time elapsed after the operation increased. The presence of Down syndrome was observed to be protective against postoperative LAVVR (p<0.05). Two patients (8%) had reoperation for LAVVR. The mean time from the initial operation to reoperation was six years. The absence of Down syndrome was found to be a risk factor for reoperation (p<0.05)\u0000 Conclusion: Repair of pAVSD is performed with low mortality and favourable outcomes. Major indication for reoperation following the initial repair of pAVSD is LAVVR and regurgitation rate increases as the time elapsed following the operation increases. Furthermore, preoperative LAVVR rate becomes higher as the operation age of the patient increases. Down syndrome is protective in terms of postoperative LAVVR whereas it is a risk factor for reoperation. High reoperation rate suggest the requirement of close follow-up.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"45 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114024898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}