Koşuyolu Heart Journal最新文献

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Takotsubo syndrome presenting with syncope and third-degree atrioventricular block requiring permanent pacemaker implantation Takotsubo综合征表现为晕厥和三度房室传导阻滞,需要植入永久性起搏器
Koşuyolu Heart Journal Pub Date : 2021-10-28 DOI: 10.51645/khj.2021.m172
Ş. Külahçıoğlu, Z. Güner, B. Kültürsay, M. Aytürk, A. Küp, A. Uslu
{"title":"Takotsubo syndrome presenting with syncope and third-degree atrioventricular block requiring permanent pacemaker implantation","authors":"Ş. Külahçıoğlu, Z. Güner, B. Kültürsay, M. Aytürk, A. Küp, A. Uslu","doi":"10.51645/khj.2021.m172","DOIUrl":"https://doi.org/10.51645/khj.2021.m172","url":null,"abstract":"Takotsubo syndrome (TS) is an acute but transient heart failure syndrome and it is very uncommon for TS to present as syncope with complete atrioventricular (AV)block.In this report,we aimed to present a case of TS complicated by third-degree AV block presented to the emergency department with syncope and requiring permanent pacemaker implantation.A 53-year-old female admitted to our emergency department with complaints of syncopal episodes and chest pain.Due to ongoing chest pain,electrocardiography (ECG) findings and segmentary wall motion abnormality on the transthoracic echocardiography (TTE),she was immediately transferred to cardiac catheterization laboratory.Coronary angiogram revealed normal coronary arteries and left ventriculography demonstrated apical ballooning and hypokinesis of the apex.As the diagnosis of TS was established,patient was transferred to coronary intensive care unit(CICU).Initial ECG at CICU demonstrated complete AV block with a heart rate of 35 beats/min.On third day of hospitalization,repeat TTE showed improved left ventricular functions with an ejection fraction of 50%.During the follow-up period in CICU,complete AV block persisted and the rhythm did not return to normal sinus rhythm after 6 days of monitorization.An electrophysiologic study demonstrated supra-hisian atrioventricular block and atrioventricular dissociation.On seventh day of hospitalization,TTE demonstrated recovered ventricular functions with an ejection fraction of 65% and a dual pacemaker was then implanted.Her third month follow-up was uneventful and TTE showed normal left ventricular functions but pacemaker interrogation revealed 99% of ventricular pacing.This case report demonstrated that,the decision to implant a permanent pacemaker on such patients should be considered on a case-by-case basis,and electrophysiologic study could be valuable on this decision.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114600646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic nutrition index may predict cerebral embolic events following carotid artery stenting procedure 预后营养指数可以预测颈动脉支架植入术后的脑栓塞事件
Koşuyolu Heart Journal Pub Date : 2021-09-15 DOI: 10.51645/khj.2021.m157
A. Güner, Özge Çelik, A. Yalçın, Murat Örten, S. Kahraman, M. Kalçık, E. G. Güner, Ç. Topel, M. Ertürk
{"title":"Prognostic nutrition index may predict cerebral embolic events following carotid artery stenting procedure","authors":"A. Güner, Özge Çelik, A. Yalçın, Murat Örten, S. Kahraman, M. Kalçık, E. G. Güner, Ç. Topel, M. Ertürk","doi":"10.51645/khj.2021.m157","DOIUrl":"https://doi.org/10.51645/khj.2021.m157","url":null,"abstract":"Objectives: Cerebral embolism after carotid artery stenting (CAS) remains a matter of concern in frailty patients. Prognostic nutrition index (PNI), which provides an objective assessment of nutritional status, is a useful prognostic indicator in cardiovascular diseases. We aim to determine the value of pre-procedural PNI in predicting cerebral embolism including stroke, transient ischemic attack (TIA), and silent new ischemic cerebral lesions (SNICLs).\u0000 Patients and Methods: We retrospectively evaluated 138 patients (mean age: 70.6±6.7 years, male:99) who underwent CAS. Inclusion criteria were as follows: I) availability of all medical records including albumin value and lymphocyte count, II) having cranial imaging after CAS, III) having symptomatic carotid stenosis 50-99% or asymptomatic carotid stenosis≥60-99%. The study population was divided into two subgroups according to the presence of cerebral embolism as cerebral embolism (+) cerebral embolism (-) groups.\u0000 Results: Among the study population, 22 patients (16%) had at least 1 SNICL, seven patients (5.0%) had ischemic stroke, and five patients (3.6%) had TIA. The cerebral embolism (+) group had a significantly lower PNI, older age, more frequent history of stroke, a higher proportion of type III aortic arch, and longer fluoroscopy time than the cerebral embolism (-) group. Low PNI was identified as one of the independent predictors of cerebral embolism (OR=0.808; 95%CI: 0.670-0.975; p=0.026), and PNI lower than 44.7 predicted cerebral embolism with a sensitivity of 70.6% and a specificity of 61.1% (AUC: 0.739; 95% CI: 0.651 to 0.827; p<0.001).\u0000 Conclusion: The current data suggest that PNI is an independent prognostic factor for cerebral embolic complications after CAS procedures.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134263213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TOTALLY ANOMALOUS PULMONARY VENOUS CONNECTION OUTCOMES FROM A SINGLE CENTER 单中心肺静脉连接完全异常
Koşuyolu Heart Journal Pub Date : 2021-09-15 DOI: 10.51645/khj.2021.m147
M. Çi̇çek, O. Korun, Okan Yurdakök, H. F. Altın, M. A. Önalan, M. Bulut, Filiz Izgi Çoşkun, A. Şaşmazel, F. Özdemir, N. Aydemir
{"title":"TOTALLY ANOMALOUS PULMONARY VENOUS CONNECTION OUTCOMES FROM A SINGLE CENTER","authors":"M. Çi̇çek, O. Korun, Okan Yurdakök, H. F. Altın, M. A. Önalan, M. Bulut, Filiz Izgi Çoşkun, A. Şaşmazel, F. Özdemir, N. Aydemir","doi":"10.51645/khj.2021.m147","DOIUrl":"https://doi.org/10.51645/khj.2021.m147","url":null,"abstract":"Objectives: There is limited data on totally anomalous pulmonary venous connection (TAPVC) repair results in our country. The aim of this study is to evaluate the early postoperative results of a large series of TAPVC patients operated in our clinic.\u0000 Patients and Methods: The data of the patients who underwent TAPVC repair in our clinic between May 2005 and May 2021 were retrospectively reviewed using hospital records\u0000 Results: A total of 150 TAPVC patients aged between 0 days and 39 years (median 3 months, IQR: 18 days – 9 months), 92 males (61%) and 58 females (39%) underwent surgical intervention. The median length of hospital stay was 12 (IQR:7-16) days. Overall mortality was 14% (21 patients). Seventeen out of 32 patients with additional cardiac anomalies (53%) and 4 out of 118 patients with isolated TAPVC (3%) died. The presence of additional cardiac anomalies was associated with mortality (p<0.00001). Mortality rate in univentricular patients was 59% (10 patients). This rate was higher in comparison to the mortality rate of biventricular patients (8%; p<0,00001). Three patients were reoperated due to postoperative pulmonary venous stenosis.\u0000 Conclusion: The TAPVC outcomes in isolated and biventricular patients were favorable with a low mortality and postoperative pulmonary venous stenosis in this cohort. Patients with a single ventricle physiology and/or heterotaxia had a significantly increased risk of mortality, which might be due to the intrinsic challenges of the univentricular physiology regarding the balance between the pulmonary and systemic circulations. Tendency for increased mortality in the cases with preoperative pulmonary venous obstruction is a potential target for improvement.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114232863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-hospital and long-term outcomes of ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention 经皮冠状动脉介入治疗st段抬高型心肌梗死患者的住院和远期预后
Koşuyolu Heart Journal Pub Date : 2021-09-15 DOI: 10.51645/khj.2021.m54
D. Oksen, Mert Sarilar, Gursu Demirci, I. Haberal, O. Abacı
{"title":"In-hospital and long-term outcomes of ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention","authors":"D. Oksen, Mert Sarilar, Gursu Demirci, I. Haberal, O. Abacı","doi":"10.51645/khj.2021.m54","DOIUrl":"https://doi.org/10.51645/khj.2021.m54","url":null,"abstract":"Objectives: We evaluated in-hospital and long-term outcomes of patients who underwent primary percutaneous coronary intervention (PCI) in a tertiary center.\u0000 Patients and Methods: We examined 1550 patients (mean age: 58.5 years, 83.1% male) admitted with acute ST-segment elevation myocardial infarction (AMI) who underwent primary PCI and were followed-up prospectively. The primary outcomes were in-hospital death and major adverse cardiac events (MACE) at follow-up.\u0000 Results: The mean duration of ischemia at admission was 2.85 ± 2.49 hours; and the mean door-to-device time was 43.2 ± 20.3 minutes. During hospitalization, all-cause mortality occurred in 73 patients (4.7%). Multivariate analysis revealed that advanced age, impaired left ventricular ejection function, high Killip functional class, hemoglobin level at admission, ventricular arrhythmias, and advanced atrioventricular block were independent predictors of poor prognosis (OR: 1.07, 0.93, 15.34, 1.44, 3.79, and 4.26, respectively). Among discharged patients with a median follow-up of 49.5 (25‒73) months, 12.4% experienced all-cause mortality, 12.5% had recurrent myocardial infarction (MI), and 2.3% had a cerebrovascular accident. The strongest independent MACE predictors were impaired left ventricular function, poor glomerular filtration rate, low albumin level, and a history of cerebrovascular disease (HR: 0.97, 0.99, 0.65, and 2.50, respectively). Secondary outcomes were contrast-induced acute kidney injury (16.7%), ventricular arrhythmias (6.1%), advanced atrioventricular block (3.7%), atrial fibrillation (7.6%), and major bleeding (1.6%).\u0000 Conclusion: AMI still has a poor long-term prognosis. These results emphasize the advantages of rapid, non-delayed revascularization. Patients should be followed-up closely after discharge in both the short- and long-term.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121084427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pacemaker lead related severe tricuspid stenosis and a history of severe COVID-19 pneumonia: A case report 起搏器导联相关性严重三尖瓣狭窄与重症COVID-19肺炎史1例
Koşuyolu Heart Journal Pub Date : 2021-08-29 DOI: 10.51645/khj.2021.m169
K. Memiç Sancar, G. Babur Guler, Enes Arslan, E. Oner, E. Güler, M. Yıldız
{"title":"Pacemaker lead related severe tricuspid stenosis and a history of severe COVID-19 pneumonia: A case report","authors":"K. Memiç Sancar, G. Babur Guler, Enes Arslan, E. Oner, E. Güler, M. Yıldız","doi":"10.51645/khj.2021.m169","DOIUrl":"https://doi.org/10.51645/khj.2021.m169","url":null,"abstract":"Tricuspid stenosis occurs after the implantation of a ventricular pacemaker lead and is a rare complication. An inflammatory response is stimulated when the pacemaker leads are passing through the tricuspid valve which leads to fibrosis in the long-term. In our case report, we aim to present a patient with asymptomatic multiple pacemaker lead related tricuspid stenosis and with a history of severe COVID-19 pneumonia.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133825057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare combination of pulmonary sling and aberrant right subclavian artery with left aortic arch in the same infant 罕见的合并肺动脉悬吊和异常右锁骨下动脉与左主动脉弓在同一婴儿
Koşuyolu Heart Journal Pub Date : 2021-08-25 DOI: 10.51645/khj.2021.m81
B. Cinar, Sezen Ugan Atik, Aysel Türkvatan Cansever, Sertaç Haydın, A. Güzeltaş
{"title":"Rare combination of pulmonary sling and aberrant right subclavian artery with left aortic arch in the same infant","authors":"B. Cinar, Sezen Ugan Atik, Aysel Türkvatan Cansever, Sertaç Haydın, A. Güzeltaş","doi":"10.51645/khj.2021.m81","DOIUrl":"https://doi.org/10.51645/khj.2021.m81","url":null,"abstract":"Although rare, vascular sling-ring complexes together in the same patient may be encountered. Once clinical complaints compatible with vascular ring anomalies are described, it should be kept in mind that more than one anomaly may be associated. By this case, the diagnostic and therapeutic course of pulmonary sling (PS) and aberrant right subclavian artery (ARSA) in an infant with breathing and feeding difficulties was presented.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121377797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Our Treatment Outcomes in Patients with Acute Deep Vein Thrombosis Associated with Congenital Inferior Vena Cava Agenesis 急性深静脉血栓合并先天性下腔静脉发育不全患者的治疗结果
Koşuyolu Heart Journal Pub Date : 2021-08-25 DOI: 10.51645/khj.2021.m139
H. Erdem, E. Selçuk
{"title":"Our Treatment Outcomes in Patients with Acute Deep Vein Thrombosis Associated with Congenital Inferior Vena Cava Agenesis","authors":"H. Erdem, E. Selçuk","doi":"10.51645/khj.2021.m139","DOIUrl":"https://doi.org/10.51645/khj.2021.m139","url":null,"abstract":"Objectives: In this study, we present the treatment outcomes of patients with acute deep venous thrombosis (DVT) associated with congenital agenesis of the inferior vena cava (IVCA).\u0000 Patients and Methods: In this retrospective study, the clinical findings and follow-up data of patients who were scheduled for an interventional procedure due to acute DVT in 2019-2021 and who were found to have IVCA in venography were analyzed retrospectively.\u0000 Results: A total of 11 patients with acute DVT associated with IVCA were identified during the study period. Eight of the patients (72.7%) were male. The mean age of the patients was 25.5±6.5 years (16-36 years). Five of the patients were followed up with conservative medical treatment. Endovascular procedure was performed in six patients. At the end of the first year, moderate post-thrombotic syndrome was found in 1 patient and mild post-thrombotic syndrome was detected in 2 patients. Patients who received only medical treatment had a significantly higher Villalta score at the end of the first year than patients who received endovascular treatment (6.6±4.1 and 2.1±1.9, p=0.04).\u0000 Conclusion: Congenital IVCA is a rare diagnosis that should be kept in mind in young patients with deep venous thrombosis. In these patients, endovascular approach may be effective to prevent postthrombotic syndrome.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122005569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Bi-ventricular systolic function on mortality in patients with sepsis and septic shock 双心室收缩功能对脓毒症和感染性休克患者死亡率的影响
Koşuyolu Heart Journal Pub Date : 2021-07-26 DOI: 10.51645/khj.2021.m120
Elif Tükenmez Tigen, A. Kepez, M. Sünbül, B. Özben, Buket Ertürk Şengel, B. Bilgili, Ş. Olgun Yıldızeli, K. Tigen
{"title":"Impact of Bi-ventricular systolic function on mortality in patients with sepsis and septic shock","authors":"Elif Tükenmez Tigen, A. Kepez, M. Sünbül, B. Özben, Buket Ertürk Şengel, B. Bilgili, Ş. Olgun Yıldızeli, K. Tigen","doi":"10.51645/khj.2021.m120","DOIUrl":"https://doi.org/10.51645/khj.2021.m120","url":null,"abstract":"Objectives: We aimed to evaluate left ventricular (LV) and right ventricular (RV) systolic performance in patients with sepsis or septic shock and possible functional alteration on in-hospital mortality.\u0000 Patients and Methods: Thirty-seven consecutive patients with the diagnosis of sepsis or septic shock were included in the study. All patients underwent comprehensive transthoracic echocardiographic examination. Data of patients discharged from the intensive care unit was compared with data of patients who died in the hospital.\u0000 Results: Fifteen patients (40.5%) survived, while 22 patients were died in the hospital (59.5%). A significant difference was detected between survivor and non-survivor groups regarding before discharge or death level of inflammatory markers such as CRP (p=0.05) and procalcitonin (p=0.03) besides BNP (p=0.01) and SOFA (p=0.009) score. There were two patients (5.4%) with EF value less than %50 in the study population. Eight patients (21.6%) displayed hypokinesia on the apical segment, and four patients (10.8%) had TAPSE values below 17 mm. One patient (6.6%) in the survivor group, but seven patients (31.8%) in the non-survivor group had apical hypokinesia with a trend towards significance (p=0.068). One patient in the survivor group (6.6%) and three patients (13.6%) in the non-survivor group had RV systolic dysfunction (p: 0.51).\u0000 Conclusion: We found a much lower rate of LV and RV systolic dysfunction in patients with sepsis or septic shock compared with previous studies. None of the myocardial dysfunction types was associated with in-hospital mortality. Apical hypokinesia was also more prevalent in non-survivors despite borderline significance.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123043109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role Of Shunt In The Norwood Procedure 分流术在诺伍德手术中的作用
Koşuyolu Heart Journal Pub Date : 2021-07-26 DOI: 10.51645/khj.2021.m113
N. Çine, F. Yiğit, Ergi̇n Arslanoğlu, H. Ceyran
{"title":"The Role Of Shunt In The Norwood Procedure","authors":"N. Çine, F. Yiğit, Ergi̇n Arslanoğlu, H. Ceyran","doi":"10.51645/khj.2021.m113","DOIUrl":"https://doi.org/10.51645/khj.2021.m113","url":null,"abstract":"Objectives: In this study we observed that the effect of post-Norwood 3.5 mm modified BTS(mBTS and 5 mm right ventricle to pulmonary (Sano modification) shunt models on clinical outcomes.\u0000 Patients and Methods: 54 patients who were operated in our hospital between 2011and 2020 years, were included in our study and this is a retrospective, observational, single-center case series study.\u0000 Results: The effect of shunt type on mortality was statistically significant, and the rate of death was lower in patients who used SANO type shunts. (p <0.05) The effect of VISC score on early mortality was significant, and VISC score was higher in the group with exitus. (p <0.05).\u0000 Conclusion: Although Sano shunt seems more preferred in Norwood, the experience of the surgeon and the center's experience may have led to variation in results at HLHS. Nevertheless, it will be clinically important for studies to evaluate the long-term results between the two shunt types.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125064760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in Clinical Features, Hemodynamic Findings and Clinical Outcomes of Ischemic and Non-ischemic Cardiomyopathy in End-Stage Heart Failure 终末期心力衰竭缺血性和非缺血性心肌病的临床特征、血流动力学表现和临床结局的差异
Koşuyolu Heart Journal Pub Date : 2021-07-26 DOI: 10.51645/khj.2021.m106
Z. Bayram, S. Efe, A. Karagoz, C. Doğan, B. Guvendi, S. Uysal, R. D. Acar, O. Akbal, Fatih Yılmaz, H. C. Tokgoz, M. Kırali, C. Kaymaz, N. Ozdemir
{"title":"Differences in Clinical Features, Hemodynamic Findings and Clinical Outcomes of Ischemic and Non-ischemic Cardiomyopathy in End-Stage Heart Failure","authors":"Z. Bayram, S. Efe, A. Karagoz, C. Doğan, B. Guvendi, S. Uysal, R. D. Acar, O. Akbal, Fatih Yılmaz, H. C. Tokgoz, M. Kırali, C. Kaymaz, N. Ozdemir","doi":"10.51645/khj.2021.m106","DOIUrl":"https://doi.org/10.51645/khj.2021.m106","url":null,"abstract":"Objectives: The aim of this study was to investigate the effect of heart failure (HF) etiology on clinical, echocardiographic, and hemodynamic findings, right ventricular (RV) function, and outcomes in patients with end-stage HF.\u0000 Patients and Methods: A total of 470 end-stage HF patients who undergoing evaluation for heart transplantation (HT) were divided into two groups: ischemic cardiomyopathy (ICMP, n=249) and nonischemic cardiomyopathy (NICMP, n=221). RV dysfunction was defined as tricuspid annular plane systolic excursion (TAPSE) ≤1.5 cm (TAPSE-defined RV dysfunction) and right ventricular stroke work index (RVSWI) <5 g/m/beat/m2 (RVSWI-defined RV dysfunction). The primary outcome was defined as left ventricular assist device implantation, urgent HT, or death.\u0000 Results: Patients with ICMP had higher pulmonary vascular resistance, systolic and mean pulmonary artery pressures (PAPs and PAPm) than those with NICMP [3.0 (1.1-6.0) vs. 2.0 (1.0-5.0),P=0.013; 53.5 (42.0-68.0) vs. 46.0 (32.5-64.5),P <0.001 and 35.512.9 vs. 31.812.3,P=0.002]. RVSWI levels were lower in NICMP patients than in ICMP patients [5.4 (3.7-7.6) vs. 6.5 (4.6-9.6),P <0.001]. While TAPSE-defined RV dysfunction was comparable between NICMP and ICMP, RVSWI-defined RV dysfunction was higher in NICMP (44.3% vs. 55.0%,P=0.069 and 45.2% vs. 31.3%,P=0.012). NICMP was an independent predictor for RVSWI-defined RV dysfunction, but not for TAPSE-defined RV dysfunction, according to multivariate analyses (OR:1.79, 95% CI:1.13-2.82,P=0.012 and OR:0.63, 95% CI:0.28-1.39,P=0.254). Over a median follow-up of 503.5 days, it was demonstrated that HF etiology was not a predictor of primary outcome according to unadjusted and adjusted models (OR:0.99, 95% CI:0.80-1.23,P=0.936 ve OR:0.89, 95% CI:0.60-1.31,P=0.542).\u0000 Conclusion: We that demonstrated patients with end-stage HF, ICMP had greater RV afterload and RVSWI value than NICMP and HF etiology was not predictor of primary outcome. However, we couldn't say for sure whether HF etiology has an effect on RV function because of the conflicting results in TAPSE-defined RV dysfunction and RVSWI-defined RV dysfunction.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117077476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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