Ç. Sarıkamış, K. Memiç Sancar, A. Birand, T. Aktemur, A. R. Demir, İffet Doğan, Ömer Aydıner, İ. Aktürk
{"title":"Distal Versus Proximal Radial Intervention; Is It Really Worth of It?","authors":"Ç. Sarıkamış, K. Memiç Sancar, A. Birand, T. Aktemur, A. R. Demir, İffet Doğan, Ömer Aydıner, İ. Aktürk","doi":"10.51645/khj.2024.427","DOIUrl":"https://doi.org/10.51645/khj.2024.427","url":null,"abstract":"Objectives: Distal transradial approach (dTRA) is a promising technique with a decreased risk of radial artery occlusion and puncture-related injuries. There has been no data which compare dTRA and proximal transradial approach (pTRA) in Turkish population group, so far. Thus, researchers aimed to compare the efficacy and safety of the dTRA versus the conventional pTRA in coronary procedures in this study.\u0000 Methods: Between September 2021 and June 2022, patients scheduled for transradial angiography at a tertiary cardiac center were enrolled in this study. Patients were randomly selected to undergo coronary imaging using either the distal dTRA or the conventional pTRA in equal numbers. A total of 79 patients were randomized to the proximal approach, and 77 patients were randomized to the dTRA. The primary endpoint was defined as procedural failure.\u0000 Results: The success rate of cannulation of the dTRA was significantly lower compared to proximal pTRA (pTRA [89.6%] and pTRA [79%] p=0.002). The rate of radial artery thrombotic complications was not different between groups (proxymal %10.6 vs. distal %5.8, p=0.288). The time of cannulation and total procedural time were longer in the dTRA group (20–40 min, median 25 min) compared to the proximal radial group (15–30 min, median 20 min) p = 0.005. However, this did not affect the total scope time duration 3.3 min. (1.6–6.4) versus 2.4 min (1.6–3.7).\u0000 Conclusion: dTRA has a relatively long access time with no advantages in terms of thrombotic complications in the radial artery.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"79 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140764718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kaya, Cemalettin Yılmaz, Mehmet Hasan Özdil, Serdar Soner, Mehmet Özbek
{"title":"Is There a Relationship between Anxiety-depression Level and SYNTAX Score in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention?","authors":"A. Kaya, Cemalettin Yılmaz, Mehmet Hasan Özdil, Serdar Soner, Mehmet Özbek","doi":"10.51645/khj.2024.390","DOIUrl":"https://doi.org/10.51645/khj.2024.390","url":null,"abstract":"Objectives: The SYNergy between percutaneous coronary interventions with TAXUS and Cardiac Surgery (SYNTAX) score is a quantitative scoring system used to evaluate the severity and extent of the disease in patients with coronary artery disease. Hospital Anxiety and Depression Scale (HADS) is a scale that measures the anxiety and depression levels of patients. The relationship between psychosocial stress and atherosclerosis is well known. In this study, we aimed to examine the relationship between SYNTAX score and HADS in patients who performed percutaneous coronary intervention due to acute coronary syndrome (ACS).\u0000 Methods: A total of 130 subjects with ACS were included in our study. The SYNTAX score, which was calculated by two independent interventional cardiologists, was divided into three groups: 0–22, low; 23–32, moderate; 33 and above, high. In our study, patients’ anxiety and depression levels were evaluated with HADS 1 month after ACS.\u0000 Results: Of the total subjects, 68, 39, and 23 patients were determined in SYNTAX scores of 0–22, 23–32, and >33 groups, respectively. A significant relationship was observed between the high SYNTAX score and the HADS-depression and anxiety scale (p<0.001, p<0.001, respectively). In the correlation analysis found that, a moderate positive correlation between the SYNTAX score and depression level, and a weak positive correlation between the SYNTAX and anxiety level (r=0.642, r=0.538, respectively).\u0000 Conclusion: In our study, we found that HADS and SYNTAX scores were significantly correlated in ACS patients who performed percutaneous coronary intervention.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"823 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140772723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive Value of Post-operative Cardiac Troponin I and Lactate Levels After Ventricular Septal Defect Closure","authors":"S. Genç, A. Ulus, Mustafa Paç","doi":"10.51645/khj.2024.425","DOIUrl":"https://doi.org/10.51645/khj.2024.425","url":null,"abstract":"Objectives: Although the mortality rate of primary ventricular septal defect (VSD) closure surgery has been reduced to <0.5% in many centers, low cardiac output syndrome and multi-organ failure syndrome development in the post-operative period are still the most common causes of mortality and morbidity. The use of biochemical markers in the early period can be used as effective predictors for reducing mortality and morbidity. In this study, the effect of post-operative serum lactate and cardiac troponin I (cTNI) levels on hospital mortality in patients who underwent primary closure of VSD was investigated retrospectively.\u0000 Methods: The effect of lactate and cTNI values on hospital mortality in 52 patients who underwent surgical repair for VSD was investigated. Serum lactate levels of all patients in the first 6 h after the operation; on the first post-operative day, cTNI values were examined retrospectively. Serum lactate levels exceeding 3.5 mmol/ lt and cTNI values exceeding 35 ng/mL were determined as the cut-off points.\u0000 Results: Serum lactate level and cTNI increase were found to be statistically different in the mortality group (p<0.05). It was shown that increased cTNI was associated with weight, left ventricular end-diastolic diameter, and cardiopulmonary bypass time (p<0.05). Serum lactate levels were 4.1±0.5 mmol/lt in the non-mortality group and 15.3±8.3 mmol/lt in the mortality group, and the difference was statistically significant (p<0.05). Hospital mortality was observed in 6 patients.\u0000 Conclusion: In patients undergoing VSD closure surgery, serum lactate levels measured in the first 6 h postoperatively and cTNI levels measured on the first post-operative day are associated with hospital mortality. Concomitant elevations of lactate and cTNI values in patients after VSD closure should suggest to take caution and early supportive treatments to reduce mortality.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"38 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140756244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Şengör, Mustafa Akbulut, S. Taş, M. Şişmanoğlu
{"title":"Clinical Outcomes and Quality of Life Following TEVAR with or without Revascularization of the Left Subclavian Artery","authors":"Mehmet Şengör, Mustafa Akbulut, S. Taş, M. Şişmanoğlu","doi":"10.51645/khj.2024.413","DOIUrl":"https://doi.org/10.51645/khj.2024.413","url":null,"abstract":"Objectives: This study aims to evaluate the clinical outcomes and quality of life of patients with or without the left subclavian artery (LSA) revascularization in patients with thoracic aortic diseases undergoing endovascular repair of the ishimaru zone 2.\u0000 Methods: A total of 48 patients with the closure of the LSA after thoracic endovascular aortic repair (TEVAR) were enrolled in the study between 2014 and 2018, of whom 21 had undergone the LSA (revascularization group), and the remaining 27 cases (non-revascularization group). The study was planned as a single-center retrospective design. Data were retrieved from the patients’ files. Short form-36 scales were administered to assess quality of life.\u0000 Results: There was no difference between the two groups with and without LSA revascularization in 30-day paraplegia (4.8% vs. 0.0%, p=0.449), 4-year cerebrovascular events (0.0% vs. 3.8%, p=0.998), upper extremity ischemia (9.6% vs. 0.0%, p=0.207), death (28.6% vs. 25.9%, p=0.887), rate of endoleak (23.8% vs. 29.6%, p=0.896), and length of intensive care unit stay (2.3±2.1 days vs. 2.1±1.8 days, p=0.645). Regarding the quality of life, only physical functioning was improved slightly more in the group that underwent LSA without revascularization (90.7±26.7 vs. 82.3±14.9, p=0.032).\u0000 Conclusion: The current study showed no significant differences with respect to neurological outcomes, upper extremity ischemia, quality of life, and mortality among patients undergoing TEVAR with or without revascularization of the LSA.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"211 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140758310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tayfun Aygün, Sait Altıntaş, H. Barman, Nurullah Yücel, Gulam Hekimoğlu, Hakan Hasdemir, Mustafa Yıldız
{"title":"Intercoronary Continuity between the Right Coronary Artery and the Left Anterior Descending Coronary Artery in the Acute Coronary Syndrome: An Anatomical View","authors":"Tayfun Aygün, Sait Altıntaş, H. Barman, Nurullah Yücel, Gulam Hekimoğlu, Hakan Hasdemir, Mustafa Yıldız","doi":"10.51645/khj.2024.428","DOIUrl":"https://doi.org/10.51645/khj.2024.428","url":null,"abstract":"Intercoronary continuity, a rare variant of the coronary circulation, is a congenital open-ended connection between two major epicardial coronary arteries. This connection may play a protective role against possible obstructive coronary artery disease or may be related to the phenomenon of coronary steal. In this case, we discuss intercoronary continuity between the right coronary artery and the left anterior descending coronary artery in the acute coronary syndrome by the anatomical view.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"62 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gokhan Demirci, A. Şahin, Mehmet Altunova, T. Aktemur, M. Tekin, Mustafa Yıldız, Mehmet Ertürk
{"title":"The Relationship of CHADS2 Score with In-stent Restenosis in Patients Undergoing Iliac Artery Stenting","authors":"Gokhan Demirci, A. Şahin, Mehmet Altunova, T. Aktemur, M. Tekin, Mustafa Yıldız, Mehmet Ertürk","doi":"10.51645/khj.2023.416","DOIUrl":"https://doi.org/10.51645/khj.2023.416","url":null,"abstract":"Objectives: Percutaneous intervention to aortoiliac occlusive disease (AIOD) is an approved choice of treatment instead of open surgery. However, despite improvement stent technology, in-stent restenosis (ISR) still remains a potential problem, especially in long-term follow-up of these patients. CHADS2 score is mainly a risk stratification tool for atrial fibrillation; however, it is found to be associated with the severity of atherosclerosis and worse outcome of percutaneous interventions. Thus, we aimed to interrogate the relationship between CHADS2 score and ISR in patients with stent implantation for AIOD.\u0000 Methods: This was a retrospective, observational study that included 419 consecutive patients who had successful common iliac artery (CIA) and external iliac artery stent implantation. Post-procedural ISR is evaluated by either ultrasonography or angiography for each patient in the follow-up period. Patients were then divided into two groups ISR (+) and ISR (–). CHADS2 score was calculated for every patient.\u0000 Results: ISR was detected in 47 out of 419 patients. Patients who had ISR had smaller stent diameter (8.4±0.9 vs. 7.2±2.8, p=0.005) and longer stent length (80 [59–120] mm vs. 59 [39–100] mm, p<0.001) than those without ISR. CHADS2 score was significantly found increased in patients with ISR than those without ISR (2.04 ± 0.98 vs. 1.45±0.93, p<0.001). Chronic obstructive pulmonary disease (COPD) (hazard ratios [HR]: 2.85, 95% confidence interval [CI]: 1.535–5.293, p=0.001), CHADS2 score (HR: 1.571, 95% CI: 1.186–2.081, p=0.002), and decreased stent diameter (HR: 0.582, 95% CI: 0.366–0.926, p=0.022) were found to be independently associated with ISR.\u0000 Conclusion: Our study demonstrated that COPD, CHADS2 score, and stent diameter were associated with ISR for patients who had successful iliac artery stent implantation. According to our study, this simple and applicable scoring system can be used to predict patients at high risk for ISR.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"80 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140770768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Soy, Mustafa Yıldız, Aslı Özmaden Hantal Özmaden Hantal, Tuba Çiftçi Küsbeci, İffet Doğan
{"title":"Pulmonary Hypertension in Connective Tissue Diseases","authors":"Mehmet Soy, Mustafa Yıldız, Aslı Özmaden Hantal Özmaden Hantal, Tuba Çiftçi Küsbeci, İffet Doğan","doi":"10.51645/khj.2024.433","DOIUrl":"https://doi.org/10.51645/khj.2024.433","url":null,"abstract":"Pulmonary hypertension (PH) is defined as mean pulmonary artery pressure >20 mmHg at rest, confirmed by right heart catheterization (RHC). The European Society of Cardiology and the European Respiratory Society (ESC/ ERS) published a new guideline in 2022 with recommendations for the classification, diagnosis, and treatment of PH. Pulmonary arterial hypertension (PAH) is a subgroup of PH and is most commonly seen together with connective tissue diseases after the idiopathic form. PAH may develop in connective tissue patients, most commonly in cases of systemic scleroderma. The presence of PAH significantly affects the quality of life and survival in connective tissue patients, especially in scleroderma. In PAH cases, early diagnosis and treatment before organ damage develops is the golden rule in treatment. Diagnosis should first be triggered by complaints such as unexplained dyspnea and syncope that develop in the presence of an underlying connective tissue disease such as scleroderma, which increases the risk of PAH and is made by RHC in the light of data obtained from examinations such as electrocardiogram, echocardiography, pulmonary function tests, and diffusing capacity for carbon monoxide. When planning treatment, pharmacological treatments are used in addition to non-pharmacological measures. Drug selection should be made by taking into account the patient’s other characteristics. Combination oral therapy with an endothelin receptor antagonist and a phosphodiesterase 5 inhibitor is often the first-line treatment in scleroderma-PAH. During follow-ups, treatment may be changed according to the patient’s clinical and laboratory data and risk analysis. For patients with functional class IV (the most severely ill patients), additional triple combination therapy consisting of a prostaglandin analog may be considered. Treatment is determined and followed according to the ERS/ESC 2022 guideline and other guidelines mostly developed in light of this guideline. Lung transplantation should not be ignored in cases resistant to these treatments. Despite current developments, the prognosis in PH cases is still poor and patients should be followed and treated in experienced centers specialized for PH.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"60 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontan Coronary Artery Dissection: What a Surprise","authors":"Gokhan Demirci, T. Aktemur, Mustafa Yıldız","doi":"10.51645/khj.2024.435","DOIUrl":"https://doi.org/10.51645/khj.2024.435","url":null,"abstract":"Spontaneous coronary artery dissection (SCAD) is a less recognized form of acute coronary syndrome, often observed in young female patients. Knowledge regarding the diagnosis and treatment of SCAD has increased in recent years, yet gaps in treatment persist. Herein, we present the case of an 18-year-old male student, who, without a regular exercise habit, started a football match on a rug without prior warm-up and experienced exertional chest discomfort, leading him to present to the emergency department with crushing chest pain. The patient, with ST elevation noted, underwent angiography, revealing SCAD in the left anterior descending artery. Managed conservatively, the patient was discharged on the 4th day with successful outcomes. Distinguishing between SCAD and coronary artery occlusion can be challenging, particularly in young patients without any medical history. Moreover, conservative treatment can prevent unnecessary percutaneous coronary intervention and potential complications.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140794875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current Position and Future Perspectives of Melatonin and Its Supplements in Pulmonary Hypertension","authors":"Mustafa Yıldız, Sahra Asena Balcıoğlu","doi":"10.51645/khj.2024.429","DOIUrl":"https://doi.org/10.51645/khj.2024.429","url":null,"abstract":"Melatonin, which is secreted principally by the pineal gland at night, affects several cardiovascular conditions including arterial hemodynamics, right ventricle functions, and pulmonary artery functions. Pulmonary hypertension is a hemodynamic and pathophysiological condition defined as an increase of average pulmonary artery pressure exceeding 20 mmHg at rest. In the light of the literature data, as discussed in this study, melatonin and its supplements may play a role in the pathogenesis and treatment of pulmonary hypertension.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"97 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140766703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}