Clinical Outcomes and Quality of Life Following TEVAR with or without Revascularization of the Left Subclavian Artery

Mehmet Şengör, Mustafa Akbulut, S. Taş, M. Şişmanoğlu
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Abstract

Objectives: This study aims to evaluate the clinical outcomes and quality of life of patients with or without the left subclavian artery (LSA) revascularization in patients with thoracic aortic diseases undergoing endovascular repair of the ishimaru zone 2. Methods: A total of 48 patients with the closure of the LSA after thoracic endovascular aortic repair (TEVAR) were enrolled in the study between 2014 and 2018, of whom 21 had undergone the LSA (revascularization group), and the remaining 27 cases (non-revascularization group). The study was planned as a single-center retrospective design. Data were retrieved from the patients’ files. Short form-36 scales were administered to assess quality of life. Results: There was no difference between the two groups with and without LSA revascularization in 30-day paraplegia (4.8% vs. 0.0%, p=0.449), 4-year cerebrovascular events (0.0% vs. 3.8%, p=0.998), upper extremity ischemia (9.6% vs. 0.0%, p=0.207), death (28.6% vs. 25.9%, p=0.887), rate of endoleak (23.8% vs. 29.6%, p=0.896), and length of intensive care unit stay (2.3±2.1 days vs. 2.1±1.8 days, p=0.645). Regarding the quality of life, only physical functioning was improved slightly more in the group that underwent LSA without revascularization (90.7±26.7 vs. 82.3±14.9, p=0.032). Conclusion: The current study showed no significant differences with respect to neurological outcomes, upper extremity ischemia, quality of life, and mortality among patients undergoing TEVAR with or without revascularization of the LSA.
进行或不进行左锁骨下动脉再通术(TEVAR)后的临床疗效和生活质量
研究目的本研究旨在评估接受ishimaru 2区血管内修复术的胸主动脉疾病患者接受或不接受左锁骨下动脉(LSA)血管再通手术的临床疗效和生活质量。研究方法2014年至2018年期间,共有48例胸主动脉内膜修复术(TEVAR)后LSA闭合的患者纳入研究,其中21例进行了LSA(血管重建组),其余27例(非血管重建组)。研究计划采用单中心回顾性设计。数据取自患者档案。采用短表-36量表评估生活质量。研究结果998)、上肢缺血(9.6% vs. 0.0%,p=0.207)、死亡(28.6% vs. 25.9%,p=0.887)、内漏率(23.8% vs. 29.6%,p=0.896)和重症监护室住院时间(2.3±2.1 天 vs. 2.1±1.8天,p=0.645)。在生活质量方面,接受 LSA 而未进行血管重建的组别中,只有身体功能的改善程度略高(90.7±26.7 vs. 82.3±14.9,P=0.032)。结论目前的研究显示,接受TEVAR治疗的患者在神经功能预后、上肢缺血、生活质量和死亡率方面与接受或不接受LSA血管再通治疗的患者没有明显差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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